Search clinical trials for: [11C]AZ10419369

Total 2192 results

Janssen Research & Development, LLC

Completed

A Study to Investigate the Regional Brain Kinetics of Brain Drug Transporters Using P-glycoprotein and Breast Cancer Resistance Protein Substrates and by Using the Positron Emission Tomography Ligand 11C-JNJ-63779586 in the Human Brain

Alzheimer Disease

Belgium
Tulane University
Louisiana Clinical and Translational Science Center

Completed

Vaccine Efficacy in Diabetic and Elderly Patients

Inflammation

United States
St. Jude Children's Research Hospital

Recruiting

Methionine PET/CT Studies In Patients With Cancer

Hodgkin Lymphoma | Osteosarcoma | Ewing Sarcoma | Ependymoma | Medulloblastoma | Non Hodgkin Lymphoma | Neuroblastoma | Craniopharyngioma | Rhabdomyosarcoma | Other | Brain Stem Glioma | Brain Tumors and/or Solid Tumors Including | High Grade CNS Tumors | Low Grade CNS Tumors

United States
Yale University

Completed

PET Imaging in Cocaine Self Administration

Cocaine Dependence

United States
Reata, a wholly owned subsidiary of Biogen

Completed

A Human AME Study for Omaveloxolone

Healthy Male Subjects

United States
Cyclerion Therapeutics

Completed

A Trial to Study the Absorption, Metabolism, and Excretion of [14C]-Olinciguat in Healthy Male Volunteers

Healthy Volunteers

United States
University of Texas Southwestern Medical Center
National Cancer Institute (NCI); Howard Hughes Medical Institute

Recruiting

An Investigation of Kidney and Urothelial Tumor Metabolism in Patients Undergoing Surgical Resection and/or Biopsy

Kidney Cancer | Renal Cell Carcinoma | Urothelial Carcinoma | Hereditary Leiomyomatosis and Renal Cell Cancer | Metastatic Urothelial Carcinoma | Chromophobe Renal Cell Carcinoma | Papillary Renal Cell Carcinoma | HLRCC | Clear Cell Carcinoma | Metastatic Kidney Cancer | Fumarate Hydratase Deficiency | Succinate...

United States
Indivior Inc.

Completed

Single Dose Study of [14C]-IDV184001AN ([14C]-IDV184001) in Healthy Adult Male Participants

Opioid Use Disorder

United States
Arcus Biosciences, Inc.
Gilead Sciences

Completed

A Study Investigating the Safety, Absorption, and Elimination of Radioactively Labeled Etrumadenant, a New Compound in the Treatment of Cancer

Healthy Participants

Netherlands
Biogen
Denali Therapeutics Inc.

Completed

A Study of Mass Balance, Pharmacokinetics, Metabolite Profile, and Metabolite Identification of BIIB122/DNL151 in Healthy Male Subjects

Healthy Volunteers

United States
PegBio Co., Ltd.
Tigermed Consulting Co., Ltd

Completed

Dose-finding of PB-119 Administered Subcutaneously Once-weekly Versus Placebo in Drug-naïve T2DM Subjects

Type 2 Diabetes Mellitus

China
Dow Pharmaceutical Sciences

Unknown

A Phase 2 Dose Ranging, Evaluator-Blinded Study to Evaluate the Safety of Topical IDP-118 (IDP-118)

Plaque Psoriasis

United States
University of Southern California
National Institute on Aging (NIA); Alzheimer's Therapeutic Research Institute; Alzheimer's Clinical Trials Consortium

Recruiting

Trial-Ready Cohort-Down Syndrome (TRC-DS) (TRC-DS)

Dementia | Alzheimer Disease | Down Syndrome

United States, Spain, United Kingdom
Tammie L. S. Benzinger, MD, PhD

Recruiting

Imaging Biomarkers in Preclinical and Symptomatic AD (ACS_PIB_IND)

Alzheimer Disease

United States
Henrik Wiggers

Completed

Cardiac Uptake of Metformin, Visualized by Positron Emission Tomography

Heart Failure, Systolic

Denmark
Turku University Hospital

Completed

PET/MRI and Biomarkers in Bladder Cancer (ACEBIB)

Bladder Cancer

Finland
Aarhus University Hospital

Completed

Metformin in Breast Cancer, Visualized With Positron Emission Tomography

Breast Cancer

Denmark
Biogen
Denali Therapeutics Inc.

Completed

A Study to Determine the Absolute Bioavailability of BIIB122/DNL151 in Healthy Subjects

Healthy Volunteers

United States
Loma Linda University

Terminated

Non-invasive Clinical Imaging of Cerebral Metabolism Following Brain Injury Using 13C Magnetic Resonance Spectroscopy.

Traumatic Brain Injury
AstraZeneca
Quotient Sciences

Completed

Study Evaluating the Pharmacokinetic and Mass Balance of Single Dose [14C] AZD5718 in Volunteers

Cardiovascular Disease

United Kingdom
Brigham and Women's Hospital
Massachusetts General Hospital

Recruiting

Feasibility of [11C]Acetate-PET in LAM and TSC

Tuberous Sclerosis Complex | Lymphangioleiomyomatosis

United States
Promontory Therapeutics Inc.

Active, not recruiting

A Study Evaluating the Safety, Pharmacokinetics, and Clinical Effects of Intravenously Administered PT-112 Injection in Subjects With Advanced Solid Tumors and Subsequent Dose Expansion Cohorts

Urogenital Neoplasms | Neoplasms by Site | Genital Neoplasms, Male | Prostatic Neoplasms | Advanced Solid Tumors | mCRPC | Metastatic Castrate-resistant Prostate Cancer | CRPC | PT-112

United States, France
Denovo Biopharma LLC

Completed

A Study of LY2140023 in Healthy Participants

Healthy Participants

United Kingdom
Athira Pharma
Alturas Analytics, Inc.; Labcorp Drug Development Inc

Completed

A Study of the Absorption, Metabolism, and Excretion of [14C]-Fosgonimeton (ATH-1017)

Healthy Volunteers

United States
University Hospital Birmingham NHS Foundation Trust
Pancreatic Cancer UK

Recruiting

The Development of a Metabolomic Test to Diagnose and Quantify Pancreatic Exocrine Insufficiency (The DETECTION Study) (DETECTION)

Pancreatic Exocrine Insufficiency

United Kingdom
Otsuka Pharmaceutical Co., Ltd.

Completed

Safety and Pharmacokinetic Study of C13-URA in Healthy Volunteers

Gastroparesis

United States
Cerevel Therapeutics, LLC

Recruiting

Positron Emission Tomography (PET) Trial to Evaluate Target Occupancy of CVL-354 at Kappa and Mu Opioid Receptors in Brain Following Oral Dosing

Opioid Use Disorder

United States
Hope Medicine (Nanjing) Co., Ltd

Recruiting

A Study to Assess the Efficacy and Safety of HMI-115 in Male Subjects With Androgenetic Alopecia

Androgenetic Alopecia

China
AstraZeneca

Completed

Absorption, Distribution, Metabolism and Excretion (ADME) Study With Single Oral Administration of [14C] NKTR-118

Healthy Volunteers

United Kingdom
University of Colorado, Denver

Terminated

Amyloid Imaging With 11C-PiB in Healthy Aging and Mild Cognitive Impairment

Alzheimer Disease | Healthy Aging

United States
GlaxoSmithKline

Completed

Positron Emission Tomography (PET) Study to Evaluate Biodistribution of [11C]-GSK2256098 in Healthy Subjects and Idiopathic Pulmonary Arterial Hypertension (PAH) Patients

Hypertension, Pulmonary

United Kingdom
Gilead Sciences

Terminated

Phase I/II Study of hLL1-DOX in Relapsed NHL and CLL

Non-Hodgkin's Lymphoma | Chronic Lymphocytic Leukemia

United States
Sidra Medical and Research Center

Completed

Predictive A1c Based on CGM Data Using CGM Data (A1c)

Diabetes Mellitus, Type 1

Qatar
Home Access Health Corporation

Completed

Comparison Study of Lay Person Finger Stick Versus Blood Draw

Diabetes

United States
Rutgers, The State University of New Jersey
National Cancer Institute (NCI)

Recruiting

Investigating Targetable Metabolic Pathways Sustaining Pancreatic Cancer

Pancreatic Ductal Adenocarcinoma

United States
PegBio Co., Ltd.

Completed

MAD Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PB-119 to Subjects With T2DM

Type2 Diabetes Mellitus

United States
Kejal Kantarci
National Institute of Neurological Disorders and Stroke (NINDS)

Enrolling by invitation

Longitudinal Imaging Biomarkers of Disease Progression in DLB

Lewy Body Disease

United States
Mayo Clinic
National Institute on Aging (NIA)

Active, not recruiting

Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's Disease

Alzheimer Disease

United States
Merck Sharp & Dohme LLC

Completed

Positron Emission Tomography (PET) Study of Brain Calcitonin Gene-Related Peptide (CGRP) Receptor Occupancy After Telcagepant Administration (MK-0974-067)

Migraine
Amsterdam UMC, location VUmc

Completed

Tumor Kinase Inhibitor Concentrations Measured by PET (PIKTURE)

Disseminated Malignant Neoplasm

Netherlands
Pfizer

Completed

A Study Testing A Radioactive Compound Given Through A Vein With And Without The Non-Radioactive Compound, Given By Mouth, To Characterize Tissue Distribution Using Positron Emission Tomography Scanning

Healthy

United States
Qlaris Bio, Inc.

Recruiting

Qlaris Study of QLS-111 in Combination With a PGA for OAG and/or OHT Patients

Glaucoma | Open-angle Glaucoma (OAG) | Ocular Hypertension (OHT)

United States
Weill Medical College of Cornell University
National Institute of Neurological Disorders and Stroke (NINDS)

Active, not recruiting

Quantitative Mapping of Substantia Nigra Iron in Parkinson's Disease (Stages I-IV, REM Sleep Behavior Disorder) and Controls

Healthy | Parkinson Disease | REM Sleep Behavior Disorder

United States
Sunnybrook Health Sciences Centre
University Health Network, Toronto; GE Healthcare; Centre for Addiction and Mental... and other collaborators

Recruiting

BEAM: Brain-Eye Amyloid Memory Study (BEAM)

Parkinson's Disease | Mild Cognitive Impairment | Lewy Body Disease | Alzheimer's Disease | Vascular Cognitive Impairment

Canada
Bausch Health Americas, Inc.
Dow Pharmaceutical Sciences

Completed

Safety and Efficacy of IDP-118 in the Treatment of Plaque Psoriasis

Plaque Psoriasis

United States
argenx

Completed

SAD and MAD Study With IV and SC Doses of ARGX-117 (ARGX-117)

Healthy Volunteers

Netherlands
Pfizer
Arvinas Estrogen Receptor, Inc.

Completed

A Study to Understand How the Study Medicine Called ARV-471 is Processed in Healthy Adults

Healthy

United States
University of California, Davis
National Institutes of Health (NIH); National Center for Complementary and...

Recruiting

EXPLORER Total Body PET/CT Imaging for Myofascial Pain

Myofascial Pain

United States
Centre for Addiction and Mental Health

Completed

MAO-B Occupancy in Depressed Patients (MOCP)

Major Depressive Disorder | Treatment Resistant Depression

Canada
Janssen Research & Development, LLC

Completed

A Study to Investigate the Regional Brain Kinetics of the Positron Emission Tomography Ligand 11C-MK-3168 and the Blocking of the Retention of the Ligand in the Human Brain by JNJ-42165279

Healthy

Belgium

Search clinical trials for: [11C]AZ10419369

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