Search clinical trials for: [14C] BIIB122 ([14C] DNL151)

Total 2752 results

Poznan University of Medical Sciences
University at Buffalo; The Greater Poland Cancer Centre

Active, not recruiting

Translational PKPD Modeling of Anti-infective Drugs Used in Pediatric Units.

Population Modeling of Anti-infective Drugs

Poland
South Plains Oncology Consortium
The Evan Foundation

Terminated

Fenretinide Lym-X-Sorb + Ketoconazole + Vincristine for Recurrent or Resistant Neuroblastoma (SPOC2013-001)

Neuroblastoma | Recurrent Neuroblastoma

United States
Bayer

Completed

Study to Find Out if Cream V61-044 Used to Treat Fungal Infections Causes an Allergic Skin Reaction to Sunlight in Healthy Participants

Dermatitis, Photoallergic

United States
Corcept Therapeutics

Completed

Mifepristone Drug-Drug Interaction Study With CYP3A Inhibitor

Healthy | Drug Interaction Potentiation

United States
GlaxoSmithKline

Completed

A Study to Assess the Safety and Interaction Between Casopitant and Ketoconazole When Taken By Healthy Adults

Nausea and Vomiting, Chemotherapy-Induced

United States
Bristol-Myers Squibb

Completed

Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BMS-986141 in Healthy Subjects

Thrombosis

United States
Pfizer

Completed

A Study to Estimate the Effect of CYP3A4 Inhibitors (Itraconazole, Diltiazem or Verapamil) on the Pharmacokinetics of Single Dose PF- 00489791 in Healthy Volunteers

Healthy Volunteers

Belgium
Indiana University
National Institutes of Health (NIH); National Institute of General Medical...

Completed

Determine the Effects of Gene Differences and Voriconazole on Enzyme CYP2B6 Activity in the Liver in Healthy Volunteers

Efavirenz, Metabolism and Pharmacokinetics Changes

United States
Boehringer Ingelheim

Completed

Effects of Single-dose and Steady-state TPV/RTV on the Steady-state Pharmacokinetics of Fluconazole in Healthy Adult Volunteers

Healthy
Shanghai Jiao Tong University School of Medicine

Completed

Efficiency Study of Clarithromycin and Bismuth-containing Quadruple Therapy to Treat H.Pylori

Functional Dyspepsia | Peptic Ulcer | Helicobacter Pylori

China
University Hospital, Grenoble

Completed

Role of Epoxy-eicosatrienoic Acids in Post-occlusive Hyperemia and Thermal Hyperemia (EETY)

Healthy Volunteers

France
Turku University Hospital

Completed

Effect of Itraconazole and Ticlopidine on the Pharmacokinetics and Pharmacodynamics of Oral Tramadol

Pharmacokinetics | Pharmacodynamics

Finland
Zodiac Produtos Farmaceuticos S.A.

Unknown

Evaluate Efficacy, Tolerability & Safety of Combination of Clindamycin and Ketoconazole for the Treatment of Mixed-Type Vaginosis, Bacterial Vaginosis and Candidiasis

Candidiasis | Bacterial Vaginosis

Brazil
The University of Texas Health Science Center,...

Terminated

Hormonal Therapy and Chemotherapy Followed by Prostatectomy in Patients With Prostate Cancer

Prostate Cancer

United States
University of Washington
GlaxoSmithKline; AstraZeneca

Completed

Maximal Suppression of the Androgen Axis in Clinically Localized Prostate Cancer (TAPS)

Cancer | Prostate Neoplasms

United States
Sahlgren´s University Hospital
Sahlgrenska University Hospital, Sweden

Withdrawn

Pain as Indication for Operative Treatment of Traumatic Rib Fractures (potf)

Pain | Trauma | Surgery | Rib Fractures

Sweden
MEDRx USA, Inc.

Completed

Etodolac-Lidocaine Patch in the Treatment of Acute Low Back Pain

Low Back Pain

United States
Pierre Fabre Dermo Cosmetique
Quanta Medical

Unknown

Efficacy, Safety and Cost-effectiveness of a Sequential Therapy With RV4104A Ointment, Ciclopiroxolamine Cream and Ciclopirox Film-forming Solution Compared With Amorolfine Nail Lacquer in Dermatophytic Onychomycosis (ONICO)

Onychomycosis

France
Université de Sherbrooke
Canadian International Development Agency

Completed

Study of the Management of Vaginal Discharge in West African Using Single Dose Treatments

Candidiasis | Vaginitis | Bacterial Vaginosis

Ghana, Guinea, Togo
Sohag University

Not yet recruiting

Pack Cross Linking for Infectious Keratitis

Infectoius Keratitis

Egypt
Radboud University Medical Center

Not yet recruiting

The Effects of Gut Micribiota Disruption on the Immune Response After Open Heart Surgery (REMEDI)

Coronary Artery Disease | Systemic Inflammatory Response Syndrome | Extracorporeal Circulation; Complications | Postoperative Shock

Netherlands
Azidus Brasil

Suspended

Efficacy and Comparative of the Association Beclomethasone Clotrimzaol + Gentamicin in Patients With Acne Contaminated (acne)

Folliculitis

Brazil
Hams Hamed Abdelrahman

Unknown

Vitamin D Oral Gel for Prevention of Radiation Induced Oral Mucositis

Oral Mucositis Due to Radiation

Egypt
Astellas Pharma Global Development, Inc.

Completed

Dose Escalation Study Investigating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics of ASP2215 in Patients With Relapsed or Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia

United States, Germany, Italy
The University of Texas Health Science Center,...

Terminated

Hormone Therapy Plus Chemotherapy as Initial Treatment for Local Failures or Advanced Prostate Cancer

Prostatic Neoplasms

United States
International Partnership for Microbicides, Inc.

Completed

To Assess the Drug-drug Interaction Potential Between Dapivirine Vaginal Ring-004, Containing 25 mg of Dapivirine, and Clotrimazole 10 mg/g (1%)

HIV- Prevention
Johns Hopkins University
National Institute of Mental Health (NIMH)

Completed

Study of Paroxetine and Fluconazole for the Treatment of HIV Associated Neurocognitive Disorder (ParaFlu)

HIV Associated Neurocognitive Disorder

United States
Farabi Eye Hospital

Unknown

UVX as an Adjuvant in the Treatment of Fungal Keratitis

Treatment
Aravind Eye Care System

Unknown

Clinical & Visual Outcomes of Collagen Cross Linking for Fungal Keratitis

Mycotic Corneal Ulcer

India
AstraZeneca
Parexel

Recruiting

Drug-Drug Interaction and Safety of AZD4041 Study (Part 1) and Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of AZD4041 Study in Opioid Use Disorder (Part 2).

Opioid Use Disorder

United States
Assistance Publique Hopitaux De Marseille

Not yet recruiting

Screen-and-treat Strategy for Vaginal Flora Abnormalities in Pregnant Women at High Risk of Preterm Birth (AUTOP2)

Bacterial Vaginosis | Premature Delivery | Vaginal Dysbiosis
TYK Medicines, Inc

Recruiting

Studies Evaluating the Effects of Itraconazole or Rifampicin on the Pharmacokinetics of TY-9591 Tablets in Healthy Subjects

NSCLC

China
State Budgetary Healthcare Institution, National...

Recruiting

First Line Chemotherapy for Classical Hodgkin Lymphoma in Russia (HL-Russia-1) (HL-Russia-1)

Hodgkin Lymphoma, Adult

Russian Federation
Vigonvita Life Sciences

Completed

Drug-Drug Interaction (DDI) Study for TPN171H

Erectile Dysfunction

China
Hutchmed

Completed

HMPL-523 CYP3A/P-gp Inhibitor and CYP Inducer Study

Relapsed or Refractory Lymphoma

United States
Seoul National University Hospital

Completed

Evaluation of Metabolic Markers for the Prediction of DDI of Various CYP3A Substrates and Inhibitors

Healthy

Korea, Republic of
Shanghai Pharmaceuticals Holding Co., Ltd

Completed

Drug-drug Interaction Study of SPH3127

Drug Drug Interaction

China
Loxo Oncology, Inc.

Completed

Study of the Effects of Itraconazole and Rifampin on LOXO-305 in Healthy Participants

Healthy Volunteers

United States
Bridge Biotherapeutics, Inc.
KCRN Research, LLC

Completed

Assess the Drug Interactions of BBT-877 and Midazolam, Itraconazole, and Esomeprazole in Healthy Adult Subjects

Healthy Participants

United States
Oxford University Clinical Research Unit, Vietnam
University of Rochester; University of Liverpool; Liverpool School of Tropical... and other collaborators

Completed

Treatment With Tamoxifen in Cryptococcal Meningitis

Hiv | Meningitis | Meningoencephalitis | Meningitis Streptococcal

Vietnam
University of Iowa

Completed

ATRA, Celecoxib, and Itraconazole as Maintenance

Relapsed Multiple Myeloma

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Ketoconazole, Dexamethasone, and Hydrocortisone in Treating Patients With Prostate Cancer That Did Not Respond to Androgen-Deprivation Therapy

Prostate Cancer
Roswell Park Cancer Institute

Completed

Calcitriol, Ketoconazole, and Dexamethasone in Treating Patients With Metastatic or Unresectable Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

United States
Vertex Pharmaceuticals Incorporated

Recruiting

A Phase 1, Open-label Study Evaluating the Pharmacokinetics and Drug-drug Interaction of VX-993 in Healthy Adults

Pain

United Kingdom
Celgene

Recruiting

A Study to Evaluate the Effect of Cytochrome P450 (CYP) 3A Inhibitor (Itraconazole) and Inducer (Rifampin) on the Drug Levels of Golcadomide (BMS-986369) in Healthy Participants

Healthy Volunteers

United States
Bayer

Recruiting

A Study to Learn About How Itraconazole and Carbamazepine Affect the Level of BAY2927088 in the Blood When These Drugs Are Taken Together by Healthy Participants

Healthy Volunteers | Advanced Non-small Cell Lung Cancer | EGFR Mutation | HER2 Mutation

United States
Manchester University NHS Foundation Trust

Not yet recruiting

Interferon-gamma as Adjunctive Therapy in Chronic Pulmonary Aspergillosis: a Randomised Feasibility Study (INCAS)

Aspergillosis | Chronic Pulmonary Aspergillosis
Eli Lilly and Company
Loxo Oncology, Inc.

Completed

A Study of the Effects of Itraconazole or Carbamazepine on LY3537982 in Healthy Participants

Healthy

United States
Zhejiang ACEA Pharmaceutical Co. Ltd.

Completed

A Study to Evaluate the Relative Bioavailability of STI-1558 and the Effect of Itraconazole and Rifampin on the Pharmacokinetics of STI-1558

COVID-19 Pneumonia

China
DICE Therapeutics, Inc.

Completed

A Drug-Drug Interaction Study to Assess the Pharmacokinetics of DC-806 When Orally Administered Alone, When Coadministered With Itraconazole, and When Coadministered With Carbamazepine in Healthy Adult Participants

Healthy Volunteers

United States

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