Search clinical trials for: [14C] Subasumstat

Total 2740 results

Takeda

Completed

Study to Assess Absolute Bioavailability of TAK-935 (OV935) and to Characterize Mass Balance, Pharmacokinetics, Metabolism, and Excretion of [14C]TAK-935 (OV935) in Healthy Male Participants

Healthy Volunteers

United States
Boehringer Ingelheim

Completed

Metabolism and Pharmacokinetics of [14C]-DK-AH 269 CL in 12 Healthy Male Volunteers

Healthy
Insmed Incorporated

Completed

A Study of the Absorption, Metabolism, and Excretion of [14C]-Brensocatib Following a Single Oral Administration in Healthy Male Participants

Healthy Volunteers

United States
Kirilys Therapeutics, Inc.

Completed

Phase 1 Study to Evaluate ASN002 Absorption, Metabolism, and Excretion of [14C] Following a Single Oral Dose in Healthy Male Subjects

Healthy Volunteer

United States
Cara Therapeutics, Inc.

Completed

Study to Evaluate the Pharmacokinetics and Metabolism of [14C] CR845 (Difelikefalin) in Patients With End Stage Renal Disease on Hemodialysis and in Healthy Subjects

Healthy | Hemodialysis

United States
GlaxoSmithKline

Completed

Radiolabel Study In Healthy Volunteers For Insomnia-Targeting Drug

Sleep Initiation and Maintenance Disorders

United Kingdom
Pfizer

Completed

Phase I Study to Determine the Absorption, Distribution, Metabolism and Excretion of Esreboxetine (ADME)

Healthy

United States
Oregon State University
National Institute of Environmental Health Sciences (NIEHS); Pacific Northwest... and other collaborators

Completed

Ultralow Dose PAH Binary Mixture Study

Environmental Exposure

United States
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Examine the Safety, Tolerability, and Pharmacokinetics of Single- and Multiple-ascending Doses of ACT-1014-6470 in Healthy Subjects

Healthy

Netherlands
Oregon State University
National Institute of Environmental Health Sciences (NIEHS); Pacific Northwest... and other collaborators

Completed

Benzo[a]Pyrene Ultralow Dose-Response Study

Environmental Exposure

United States
Sunshine Lake Pharma Co., Ltd.

Completed

Study on the Body Mass Balance and Biotransformation of [14C]-HEC585

Healthy Volunteer

China
MedDay Pharmaceuticals SA
Quotient Sciences

Completed

Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-MD1003 in Healthy Male Subjects

Healthy Volunteers

United Kingdom
Eli Lilly and Company

Completed

A Study of LY2940680 in Healthy Participants

Healthy Volunteers

United States
Eli Lilly and Company

Terminated

A Study of [14C]-LY3023703 in Healthy Participants

Healthy Volunteers

United States
GlaxoSmithKline

Completed

A Single Dose Study to Determine the Excretion, Balance and Metabolic Disposition of Radiolabelled GW642444.

Pulmonary Disease, Chronic Obstructive

Netherlands
Amicus Therapeutics

Completed

A Study to Assess the Absorption, Metabolism and Excretion of Migalastat Hydrochloride (AT1001-014)

Fabry Disease
Eli Lilly and Company

Completed

A Study of LY2157299 Monohydrate in Healthy Volunteers

Healthy Volunteers

United States
AstraZeneca

Terminated

Open-Label Absorption, Distribution, Metabolism, Excretion (ADME) and Pharmacokinetics (PK) Following a Single Oral Dose of AZD1236 in Healthy Male Subjects

Healthy

United Kingdom
Kazia Therapeutics Limited
Quotient Sciences

Completed

Mass Balance Recovery, Metabolite Profile, and Metabolite Identification of [14C]-Paxalisib in Healthy Male Subjects

Healthy

United Kingdom
Aristea Therapeutics, Inc.

Completed

A Study of the ADME of [14C]RIST4721 in Healthy Male Subjects

Healthy | ADME

United Kingdom
GlaxoSmithKline
Hammersmith Medicines Research

Completed

A Microdose Study in Healthy Subjects to Describe Intravenous Pharmacokinetics of GSK3191607

Malaria, Falciparum

United Kingdom
GlaxoSmithKline

Completed

A Study to Investigate the Recovery, Excretion, and Pharmacokinetics of 14C -GSK1322322 After an Intravenous and an Oral Dose

Infections, Bacterial

United States
Eli Lilly and Company

Completed

A Study of Carbon-14-Labeled [14C]-LY3549492 in Healthy Participants

Healthy Male

United Kingdom
Ascentage Pharma Group Inc.

Completed

The Absorption, Metabolism and Excretion of [14C]APG-2575 in Healthy Subjects

Pharmacokinetics

China
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

Study of Radiolabeled Danicopan in Healthy Male Participants

Healthy

New Zealand
Chugai Pharmaceutical

Completed

Excretion Balance, PK and Metabolism of a Single Oral Dose of [14C]PCO371

Healthy Volunteers

United Kingdom
Eli Lilly and Company

Completed

A Study of Carbon-14-Labeled LY2835219 ([^14C]-LY2835219) in Healthy Participants

Healthy Volunteers

United States
GlaxoSmithKline

Completed

GSK2251052 Mass Balance in Healthy Adult Subjects

Community-acquired Infection

Netherlands
Yuhan Corporation

Completed

AME Study of [14C]-YH4808 in Healthy Male Subjects

Healthy

United States
Bristol-Myers Squibb

Completed

Absorption, Distribution, Metabolism and Excretion (ADME) Study of BMS-986020

Immunosuppression For Disease
Pfizer

Completed

Radiolabel ADME (Absorption, Distribution, Metabolism, and Excretion) Study Of [14C] PF-00868554 In Healthy Adult Male Subjects

HCV

United States
Corcept Therapeutics

Completed

Absolute Bioavailability and Metabolism Study of CORT118335 in Healthy Male Participants

Healthy

United Kingdom
Xuanzhu Biopharmaceutical Co., Ltd.

Not yet recruiting

A Study of the Absorption, Metabolism and Excretion of [14C]XZP-3621 in Human

Healthy Volunteers

China
Supernus Pharmaceuticals, Inc.

Completed

Mass Balance Study of NV-5138 in Healthy Male Subjects

Healthy Volunteers

United Kingdom
Zeria Pharmaceutical

Completed

Mass Balance and Metabolism Study of 14C-Z-215

Healthy Male Subjects

United Kingdom
Hepion Pharmaceuticals, Inc.

Completed

Single Dose ADME Study of [14C]-Rencofilstat in Healthy Male Subjects

NASH With Fibrosis

United Kingdom
Zhejiang ACEA Pharmaceutical Co. Ltd.

Completed

[14C] Study on Mass Balance and Biotransformation of STI-1558 in Healthy Chinese Adult Male Subjects

COVID-19

China
Bayer

Completed

A Trial to Learn How a New Liquid Form of BAY1817080 is Tolerated and Taken up by the Body of Healthy Male Participants (Part A). By Labeling BAY1817080 With a Radioactive Substance (Carbon 14) Researchers Want to Learn How the Study Drug is Processed and Excreted by the Body After Dosing (Part B)

Overactive Bladder | Diabetic Neuropathic Pain | Endometriosis Related Pain | Refractory or Unexplained Chronic Cough

Netherlands
Navitor Pharmaceuticals, Inc.
Supernus Pharmaceuticals, Inc.

Completed

Mass Balance Study of NV-5138 in Healthy Male Subjects.

Healthy Volunteers

United Kingdom
Celgene

Completed

A Study to Evaluate the Metabolism and Excretion of [14C]-CC-92480 in Healthy Male Participants

Healthy Volunteers

United States
Nanjing Sanhome Pharmaceutical, Co., Ltd.

Completed

The Absorption, Metabolism and Excretion of [14C]SH-1028 in Chinese Healthy Male Volunteers

Healthy Male Volunteers

China
Nerre Therapeutics Ltd.

Completed

Mass Balance Study of [14C]-Orvepitant Oral Solution in Healthy Male Subjects

Healthy

United Kingdom
Crinetics Pharmaceuticals Inc.

Completed

Mass Balance and Pharmacokinetics of [14C]-CRN00808 in Healthy Volunteers

Healthy Volunteers

Netherlands
Concert Pharmaceuticals
Celerion

Completed

Study Evaluating Pharmacokinetics and Mass Balance of [14C]-CTP-543 in Healthy Adult Male Volunteers

Healthy Volunteers

United States
Celtaxsys, Inc.
Quotient Sciences

Completed

Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-Acebilustat (CTX-4430)

Heathy Volunteers

United Kingdom
Celgene

Completed

Radiolabeled Study of CC-220 in Healthy Male Subjects

Healthy Volunteer

United States
AstraZeneca

Completed

Bioavailability of AZD0284 and IV Microtracer Study

Plaque Psoriasis Vulgaris

United Kingdom
Boehringer Ingelheim

Completed

Olmutinib (BI 1482694) ADME Study

Healthy

Netherlands
Boehringer Ingelheim

Completed

Investigation of the Metabolism and Pharmacokinetics of Ambroxol in Healthy Male Volunteers

Healthy
Cyclerion Therapeutics

Completed

A Trial to Study the Absorption, Metabolism, and Excretion of [14C]-Praliciguat in Healthy Male Volunteers

Healthy Volunteers

United States

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