Search clinical trials for: 0.9% NaCl physiological saline Nasal-spraying

Total 1196 results

University Hospital Inselspital, Berne

Completed

Hypertonic Saline for Fluid Resuscitation After Cardiac Surgery (HERACLES)

Cardiovascular Diseases | Valvular Heart Disease

Switzerland
Atox Bio Ltd
Biomedical Advanced Research and Development Authority

Completed

Phase III Efficacy and Safety Study of AB103 in the Treatment of Patients With Necrotizing Soft Tissue Infections (ACCUTE)

Necrotizing Fasciitis | Necrotizing Soft Tissue Infections | Fournier's Gangrene

United States, France
Hamilton Health Sciences Corporation

Completed

Hypotonic Versus Isotonic Parenteral (HIP) Fluid Trial

Hyponatremia | Hypernatremia

Canada
Noveome Biotherapeutics, formerly Stemnion

Completed

Safety, Efficacy and Treatment Regimen Study of ST266 in Subjects With Moderate to Severe Periodontitis

Periodontal Disease

United States
Vasopharm GmbH

Completed

Phase 2 a Study to Assess Safety and Pharmacokinetics of VAS203 in Patients With Traumatic Brain Injury (NOSTRA)

Traumatic Brain Injury

Austria, France, Spain, Switzerland, United Kingdom
Medical University of Vienna

Completed

Changes in Adaptive Immune Responses and Effector Cell Responses Upon Nasal Allergen Exposure - a Pilot Study

Allergic Rhinitis | Allergic Inflammation

Austria
University of Haifa
Western Galilee Hospital-Nahariya

Recruiting

Physiological, Cognitive, and Personal Features in the Link Between Placebo-effect and Variability of Pain Reports

Chronic Back Pain

Israel
Meshalkin Research Institute of Pathology of Circulation

Completed

The Efficacy and Safety of Hypertonic Saline in Cardiac Surgery Patients. (ESHHS)

Coronary Artery Disease | Edema

Russian Federation
University Hospital, Basel, Switzerland
Fresenius AG

Completed

BaSES Trial: Basel Starch Evaluation in Sepsis (BaSES)

Sepsis | Septic Shock | Severe Sepsis

Switzerland
Polyheal Ltd.

Unknown

Study to Evaluate Polyheal-1 in Treatment of Recalcitrant Wounds

Wounds and Injuries

Israel
University of Arkansas

Recruiting

Candida Therapeutic Vaccine in Head and Neck Cancer Patients to Reduce Recurrence

Squamous Cell Carcinoma of Head and Neck

United States
Alnylam Pharmaceuticals

Completed

A Safety and Tolerability Study of an Investigational Drug, ALN-TTRSC02, in Healthy Subjects

Transthyretin-mediated Amyloidosis (ATTR Amyloidosis)

United Kingdom
Alnylam Pharmaceuticals
The Medicines Company

Completed

A Phase 1 Study of an Investigational Drug, ALN-PCSSC, in Subjects With Elevated Low Density Lipoprotein Cholesterol (LDL-C)

Hypercholesterolemia

United Kingdom
Alnylam Pharmaceuticals

Completed

Trial to Evaluate Safety, Tolerability, and Parmacokinetics of ALN-TTR02 in Healthy Volunteer Subjects

TTR-mediated Amyloidosis

United Kingdom
Alnylam Pharmaceuticals

Completed

Trial to Evaluate Safety and Tolerability of ALN-PCS02 in Subjects With Elevated LDL-Cholesterol (LDL-C)

Elevated LDL-Cholesterol (LDL-C)

United Kingdom
Alnylam Pharmaceuticals

Completed

Trial to Evaluate Safety and Tolerability of ALN-TTR01 in Transthyretin (TTR) Amyloidosis

Transthyretin Mediated Amyloidosis (ATTR)

United Kingdom, France, Portugal, Sweden
Arrowhead Pharmaceuticals

Completed

Study of ARO-ANG3 in Healthy Volunteers and in Dyslipidemic Patients

Dyslipidemias | Hypertriglyceridemia | Familial Hypercholesterolemia

Australia, New Zealand
Arrowhead Pharmaceuticals

Completed

Study of ARO-APOC3 in Healthy Volunteers, Hypertriglyceridemic Patients and Patients With Familial Chylomicronemia Syndrome (FCS)

Hypertriglyceridemia | Familial Chylomicronemia

Australia, Canada, New Zealand
Alnylam Pharmaceuticals

Completed

A Phase 1/2 Study of an Investigational Drug, ALN-CC5, in Healthy Adult Volunteers and Patients With PNH

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Spain, United Kingdom
Karolinska Institutet
Danderyd Hospital

Completed

Endotoxin-induced Inflammatory and Behavioral Responses and Predictors of Individual Differences

Sickness Behavior
University Hospital, Basel, Switzerland

Completed

Smoking Cessation Facilitated by Glucagon-like Peptide-1 (GLP-1) Analogues (SKIP)

Smoking Cessation | Craving | Weight Change, Body | Glucagon-like Peptide-1

Switzerland
Ahmed Mohamed ELbadawy

Unknown

Prophylaxis Versus Treatment for TURP Syndrome.

Transurethral Resection of Prostate Syndrome

Egypt
Alnylam Pharmaceuticals

Completed

ENDEAVOUR: Phase 3 Multicenter Study of Revusiran (ALN-TTRSC) in Patients With Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC)

Amyloid Neuropathies | Amyloid Neuropathies, Familial | Amyloidosis, Hereditary | Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC) | Amyloidosis, Hereditary, Transthyretin-Related | Familial Transthyretin Cardiac Amyloidosis

United States, France, Italy, Spain, Canada, Germany, Belgium, Sweden, United Kingdom
Alnylam Pharmaceuticals

Completed

A Phase 1 Study of Givosiran (ALN-AS1) in Patients With Acute Intermittent Porphyria (AIP)

Acute Intermittent Porphyria

United States, United Kingdom, Sweden
MiMedx Group, Inc.

Completed

Micronized dHACM Injectable for the Treatment of Plantar Fasciitis (dHACM)

Fasciitis, Plantar

United States
Alnylam Pharmaceuticals

Completed

APOLLO: The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis

Amyloid Neuropathies | Amyloid Neuropathies, Familial | TTR-mediated Amyloidosis | Amyloidosis, Hereditary | Amyloidosis, Hereditary, Transthyretin-Related | Familial Amyloid Polyneuropathies

United States, Canada, Argentina, Australia, Bulgaria, Cyprus, Italy, Japan, Malaysia, Mexico, Netherlands, Portugal, Spain, Sweden, Germany, France, Brazil, Turkey, Korea, Republic of, Taiwan, United Kingdom
Alnylam Pharmaceuticals

Completed

A Phase 1, Single- and Multi-Dose, Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneously Administered ALN-TTRSC (Revusiran) in Healthy Volunteers

TTR-mediated Amyloidosis

United Kingdom
Alnylam Pharmaceuticals

Active, not recruiting

HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

United States, Poland, Argentina, Australia, Belgium, France, Germany, Japan, Netherlands, Portugal, Spain, Sweden, United Kingdom, Canada, Czechia, Denmark, Hungary, Ireland, Norway, Korea, Republic of, Austria, Croatia, Israel, Latvia, Lithuan... and more
Universitas Bali Internasional

Completed

The Effects of Intra-articular Platelet-Rich Plasma Injection on The Severity of Knee Osteoarthritis

Osteoarthritis, Knee

Indonesia
Arrowhead Pharmaceuticals

Completed

Study of ARO-HSD in Healthy Volunteers and Patients With Non-Alcoholic Steatohepatitis (NASH) or Suspected NASH

Non-alcoholic Steatohepatitis

New Zealand
Dicerna Pharmaceuticals, Inc.

Completed

Study to Evaluate Safety, Tolerability, PK and PD of DCR-PHXC in PH Type 3 Patients (PHYOX4)

Primary Hyperoxaluria Type 3

United States, Germany, Netherlands, United Kingdom
Arrowhead Pharmaceuticals

Completed

Study of ARO-HBV in Normal Adult Volunteers and Patients With Hepatitis B Virus (HBV)

Hepatitis B

Australia, Hong Kong, New Zealand
Alnylam Pharmaceuticals

Completed

A Study of the Safety, Tolerability and Pharmacokinetics of ALN-TTR02 in Japanese Healthy Volunteers

Transthyretin (TTR)-Mediated Amyloidosis

United Kingdom
Ionis Pharmaceuticals, Inc.
Akcea Therapeutics

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS APO(a)-LRx in Healthy Volunteers With Elevated Lipoprotein(a)

Elevated Lipoprotein(a)

Canada
Zurita Laboratorio Farmaceutico Ltda.

Unknown

A Study of Luffa Operculate Nasal Solution 5mg/mL Compared With Saline (NaCl 09%) for the Relief of Nasal Obstruction

Sinusitis | Rhinitis

Brazil
Assistance Publique - Hôpitaux de Paris

Completed

Ilomedin in Septic Shock With Persistent Microperfusion Defects (I-MICRO) (I-MICRO)

Septic Shock Hyperdynamic

France
Rawalpindi Medical College

Completed

Effect of Hot Saline Irrigation on the Operative Field During Endoscopic Sinus Surgery

Rhinosinusitis

Pakistan
Hospital General de Niños Pedro de Elizalde

Completed

Variation in Natremia Using Two Different Maintenance Intravenous Fluids in Postsurgical Hospitalized Children (surgical-Na)

Hyponatremia

Argentina
University of Arkansas, Fayetteville
Danone Research

Completed

The Effect of Vasopressin on Glucose Regulation (HYPERGlu)

Insulin Resistance

United States
Rigshospitalet, Denmark

Completed

Acute Exercise and NK Cell Regulation in Tissue and Circulation After IL-6R Blockade

Appetitive Behavior | Physical Stress | Interleukin-6 Inhibition

Denmark
MiMedx Group, Inc.

Completed

Micronized dHACM Injectable for the Treatment of Plantar Fasciitis

Fasciitis, Plantar

United States
MiMedx Group, Inc.

Completed

Micronized dHACM Injectable for the Treatment of Achille Tendonitis

Tendonitis;Achilles

United States
Noveome Biotherapeutics, formerly Stemnion

Completed

Evaluation of the Effectiveness of ST266 Ophthalmic Drops Compared to Placebo to Treat Allergic Conjunctivitis

Allergic Conjunctivitis

United States
Larissa University Hospital

Completed

Effect of Nasopharyngeal Wash With Normal Saline on SARS-CoV2 Viral Load

SARS-CoV2 Infection

Greece
Chulalongkorn University
National Research Council of Thailand

Terminated

Randomized Controlled Study of the Effectiveness of IV Fluid Infusion in Patients With Acute Ischemic Stroke (IVIS) (IVIS)

Ischemic Stroke

Thailand
Huro Biotech Joint Stock Company
Thai Binh University of Medicine and Pharmacy

Completed

Safety Evaluation of Intranasal Use of DSM 32444 Postbiotic in Humans

Rhino Sinusitis

Vietnam
IRCCS National Neurological Institute "C. Mondino...
University of Pavia

Recruiting

Habituation of the Nociceptive Blink Reflex in Experimentally Induced Migraine Attack

Pain | Migraine | Migraine Disorders

Italy
Arrowhead Pharmaceuticals

Completed

Study of ARO-AAT in Normal Adult Volunteers

Alpha 1-Antitrypsin Deficiency

New Zealand
Alnylam Pharmaceuticals

Terminated

A Study of an Investigational Drug, ALN-AAT, in Healthy Adult Subjects and Patients With ZZ Type Alpha-1 Antitrypsin Deficiency Liver Disease

Antitrypsin Deficiency Liver Disease

United Kingdom
Stefania La Grutta, MD

Completed

Effects of Hypertonic Saline Solution (NACL 3%+NAHCO3) on Nasal Inflammation in Children With AR. RinASol- Pilot Study (RinASol)

Allergic Rhinitis

Italy

Search clinical trials for: 0.9% NaCl physiological saline Nasal-spraying

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