Search clinical trials for: 11C-PS13

Total 2247 results

GlaxoSmithKline

Completed

Radiolabel Study In Healthy Volunteers For Insomnia-Targeting Drug

Sleep Initiation and Maintenance Disorders

United Kingdom
Protalix

Completed

An Open-Label, Dose Escalation Study to Evaluate the Safety and the Pharmacokinetics of Oral PRX-112

Gaucher Disease

Israel
Santen Pharmaceutical Co., Ltd.

Completed

A Pharmacokinetic Study of DE-117 Ophthalmic Solution in Healthy Adult Male Subjects - Phase I Study -

Healthy Male Adults

Japan
Pfizer

Completed

Phase I Study to Determine the Absorption, Distribution, Metabolism and Excretion of Esreboxetine (ADME)

Healthy

United States
Celltrion

Completed

To Compare the Efficacy, Pharmacokinetics and Safety Between CT-P13 and China Approved Remicade When Co-administered With Methotrexate in Patients With Active Rheumatoid Arthritis

Rheumatoid Arthritis

China
Rutgers, The State University of New Jersey
Ludwig Institute for Cancer Research

Not yet recruiting

Investigating the Metabolic Pathways in Hormone Receptor Positive/HER2 Negative Breast Cancer

Breast Cancer

United States
argenx

Recruiting

A Phase 3 Study to Evaluate the Safety and Efficacy of Efgartigimod PH20 Subcutaneous in Adult Patients With Primary Immune Thrombocytopenia (ADVANCE SC+)

Primary Immune Thrombocytopenia

United States, Australia, Bulgaria, China, Georgia, Greece, Italy, Japan, Poland, Portugal, Romania, Russian Federation, Thailand, Turkey, Argentina, Chile, Ireland, Jordan, Tunisia, Korea, Republic of, Mexico, New Zealand, South Africa and more
AbbVie

Terminated

Study to Evaluate Adverse Events and Change in Disease Activity With Oral Capsules of Galicaftor/Navocaftor/ABBV-119 or Galicaftor/Navocaftor/ABBV-576 Combination Therapies in Adult Participants With Cystic Fibrosis

Cystic Fibrosis (CF)

United States, Australia, Belgium, Hungary, Netherlands, New Zealand, Slovakia, United Kingdom
Angiocrine Bioscience
California Institute for Regenerative Medicine (CIRM)

Completed

Trial of AB-110 in Adults With Hematologic Malignancies Undergoing Cord Blood Transplantation

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Acute Lymphoblastic Leukemia in Remission | Other Acute Leukemias

United States
Gilead Sciences

Completed

Phase I/II Study of hLL1 in Multiple Myeloma

Multiple Myeloma | Myeloma, Plasma-Cell | PLASMACYTOMA

United States
miRagen Therapeutics, Inc.

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MRG-110 Following Intradermal Injection in Healthy Volunteers

Healthy Volunteer

United States
Universitaire Ziekenhuizen KU Leuven

Completed

A Dose-finding and Feasibility Study for a Prolonged 13C-octanoate Breath Test for Gastric Emptying (ANTERO-AC-7)

Healthy | Gastric Emptying

Belgium
Oregon State University
National Institute of Environmental Health Sciences (NIEHS); Pacific Northwest... and other collaborators

Completed

Ultralow Dose PAH Binary Mixture Study

Environmental Exposure

United States
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Examine the Safety, Tolerability, and Pharmacokinetics of Single- and Multiple-ascending Doses of ACT-1014-6470 in Healthy Subjects

Healthy

Netherlands
Michael Ohliger, MD PhD
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Hyperpolarized Pyruvate (13C) Magnetic Resonance Imaging In Patients With Fatty Liver Disease

NAFLD | Non-Alcoholic Fatty Liver Disease | NASH | Non Alcoholic Fatty Liver | Non Alcoholic Steatohepatitis

United States
Bayer

Completed

A Study to Learn How BAY2927088 is Taken up and Handled by the Body in Healthy Male Participants

Healthy Volunteers | Advanced Non-small Cell Lung Cancer | EGFR Mutation | HER2 Mutation

Netherlands
Debiopharm International SA

Completed

Mass Balance Recovery and Metabolic Profile of 14C Debio 1450 Following Single Oral and Intravenous Doses in Healthy Male Subjects

Healthy

United Kingdom
Praxis Precision Medicines

Terminated

A Clinical Trial of PRAX-114 in Participants With Post-Traumatic Stress Disorder

Stress Disorders, Post-Traumatic | Trauma and Stressor Related Disorders | Post Traumatic Stress Disorder | Stress Disorder | Post-traumatic Stress Disorder | Mental Disorder

United States
Imperial College London

Terminated

A Human In Vivo Feeding Study Of The Blood Monocyte Response To Dietary Lipid Intake (Lipophage14)

Atherosclerosis

United Kingdom
Peking Union Medical College Hospital

Not yet recruiting

Characterizing LAM With 11C-Choline PET/CT

Lymphangioleiomyomatosis

China
Centre for Addiction and Mental Health

Completed

Exploring Regulation and Function of Dopamine D3 Receptors in Alcohol Use Disorders: A [11C]-(+)-PHNO Study

Alcohol Use Disorder

Canada
Boehringer Ingelheim

Completed

Metabolism and Pharmacokinetics of [14C]-DK-AH 269 CL in 12 Healthy Male Volunteers

Healthy
BioMarin Pharmaceutical

Completed

A Double-Blind Study to Evaluate the Efficacy and Safety of BMN 110 in Patients With Mucopolysaccharidosis IVA (Morquio A Syndrome)

MPS IV A

United States, Canada, France, United Kingdom, Taiwan, Argentina, Colombia, Japan, Saudi Arabia, Netherlands, Denmark, Korea, Republic of, Brazil, Germany, Portugal, Italy, Qatar
Takeda

Completed

Study to Assess Absolute Bioavailability of TAK-935 (OV935) and to Characterize Mass Balance, Pharmacokinetics, Metabolism, and Excretion of [14C]TAK-935 (OV935) in Healthy Male Participants

Healthy Volunteers

United States
Celltrion

Completed

CT-P13 (Infliximab) Subcutaneous Administration in Patients With Moderately to Severely Active Ulcerative Colitis (LIBERTY-UC)

Ulcerative Colitis

Poland
Bausch Health Americas, Inc.

Completed

Safety and Efficacy of IDP-118 Lotion to Ultravate® in the Treatment of Plaque Psoriasis

Psoriasis

United States
IRCCS San Raffaele

Completed

11C-choline PET/CT Based Helical Tomotherapy as Innovative Treratment Approach for Bone Metastases in Prostate Cancer Patients.

Prostate Cancer

Italy
University of Pennsylvania
Washington University School of Medicine; Yale University; University of Maryland and other collaborators

Completed

11C-acetate/18Fluorodeoxyglucose-FDG PET/CT and Cardiac MRI in Pulmonary Hypertension

Pulmonary Hypertension

United States
Commissariat A L'energie Atomique
Assistance Publique - Hôpitaux de Paris

Unknown

Evaluation of 11 C-Choline PET-CT for Detection of Hepatocellular Carcinoma (CHOLPET)

Hepatocellular Carcinoma

France
Nocion Therapeutics

Completed

Placebo-controlled, Single and Multiple Dose Study in Healthy Volunteers and Refractory Chronic Cough Patients to Assess the Safety, Tolerability, and Pharmacokinetics of Two Formulations of NTX-1175

Refractory Chronic Cough

United States
Cardix Therapeutics LLC

Not yet recruiting

An Exploratory Safety and Efficacy Clinical Study of CARDIX-101 for the Treatment of Chronic Bradycardia

Bradycardia
Kazia Therapeutics Limited
Quotient Sciences

Completed

Mass Balance Recovery, Metabolite Profile, and Metabolite Identification of [14C]-Paxalisib in Healthy Male Subjects

Healthy

United Kingdom
University of Texas Southwestern Medical Center

Completed

Pediatric Solid Tumor Metabolism [A Prospective Study Exploring Metabolism of Solid Tumors in Pediatrics]

Sarcoma | Neuroblastoma | Pediatric Cancer

United States
Aristea Therapeutics, Inc.

Completed

A Study of the ADME of [14C]RIST4721 in Healthy Male Subjects

Healthy | ADME

United Kingdom
GlaxoSmithKline
Hammersmith Medicines Research

Completed

A Microdose Study in Healthy Subjects to Describe Intravenous Pharmacokinetics of GSK3191607

Malaria, Falciparum

United Kingdom
Radboud University Medical Center

Completed

Effects of Oxygen Status on Endotoxemia Induced Inflammation and Hypoxia Inducible Factor-1α

Hypoxia | Hyperoxia | Normoxia

Netherlands
argenx

Not yet recruiting

A Phase 1b Study to Investigate Safety and Tolerability of ARGX-119 in Adult Participants With DOK7-Congenital Myasthenic Syndromes (CMS)

Congenital Myasthenic Syndrome
Lipum AB
QPS Netherlands B.V.

Recruiting

First in Human Study of a Monoclonal Antibody (SOL-116) Targeting BSSL (Bile Salt-Stimulated Lipase), Single and Multiple Dose Parts

Rheumatoid Arthritis

Netherlands
Eli Lilly and Company

Completed

A Study of Carbon-14-Labeled [14C]-LY3549492 in Healthy Participants

Healthy Male

United Kingdom
Andrew Dauber

Active, not recruiting

Vosoritide for Selected Genetic Causes of Short Stature

Short Stature

United States
Ascentage Pharma Group Inc.

Completed

The Absorption, Metabolism and Excretion of [14C]APG-2575 in Healthy Subjects

Pharmacokinetics

China
Taisho Pharmaceutical Co., Ltd.

Completed

Mass Balance Study of TS-142 in Healthy Adult Subjects.

Healthy Male Subjects

Japan
Syndesi Therapeutics
P1vital Limited

Withdrawn

A Study of SDI-118 in Participants in Remission From Depression

Depression in Remission

United Kingdom
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

Study of Radiolabeled Danicopan in Healthy Male Participants

Healthy

New Zealand
Chugai Pharmaceutical

Completed

Excretion Balance, PK and Metabolism of a Single Oral Dose of [14C]PCO371

Healthy Volunteers

United Kingdom
Eli Lilly and Company

Completed

A Study of Carbon-14-Labeled LY2835219 ([^14C]-LY2835219) in Healthy Participants

Healthy Volunteers

United States
GlaxoSmithKline

Completed

GSK2251052 Mass Balance in Healthy Adult Subjects

Community-acquired Infection

Netherlands
Yuhan Corporation

Completed

AME Study of [14C]-YH4808 in Healthy Male Subjects

Healthy

United States
Bristol-Myers Squibb

Completed

Absorption, Distribution, Metabolism and Excretion (ADME) Study of BMS-986020

Immunosuppression For Disease
Pfizer

Completed

Radiolabel ADME (Absorption, Distribution, Metabolism, and Excretion) Study Of [14C] PF-00868554 In Healthy Adult Male Subjects

HCV

United States

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