Search clinical trials for: 11C-Trimethoprim

Total 2398 results

Jacobio Pharmaceuticals Co., Ltd.

Completed

Mass Balance Study of [14C]JAB-21822

Mass Balance Study in Healthy Subjects

China
Aptabio Therapeutics, Inc.
Covance

Terminated

A Phase 2 Study of APX-115 in Hospitalized Patients With Confirmed Mild to Moderate COVID-19.

COVID-19

United States
argenx

Completed

A Safety and Tolerability Study of ARGX-113 in Patients With Myasthenia Gravis Who Have Generalized Muscle Weakness. (ADAPT+)

Generalized Myasthenia Gravis

United States, Belgium, Canada, Czechia, Denmark, France, Georgia, Germany, Hungary, Italy, Japan, Netherlands, Poland, Russian Federation, Serbia
Shandong Luoxin Pharmaceutical Group Stock Co.,...

Completed

Mass Balance and Biotransformation Study of [14C]LXI-15028 in Humans

Healthy Subjects | Pharmacokinetics of 14C-labeled of LXI-15028

China
Veru Inc.

Completed

VERU-111 in the Treatment of SARS-Cov-2 Infection by Assessing Its Effect on the Proportion of Patients Who Die on Study (VERU-111)

SARS-CoV Infection

United States, Argentina, Brazil, Bulgaria, Colombia, Mexico
Sunshine Lake Pharma Co., Ltd.

Completed

ADME Study of [14C] Antaitavir Hasophate in Healthy Male Subjects

Healthy Male Subjects

China
Veru Inc.

Completed

COVID-19 Treatment of Severe Acute Respiratory Syndrome With Veru-111

Respiratory Distress Syndrome, Adult

United States
argenx

Approved for marketing

Efgartigimod Expanded Access for Generalized Myasthenia Gravis

Generalized Myasthenia Gravis

United States
H. Lundbeck A/S

Completed

A Study Investigating Lu AG06466 in Healthy Men

Healthy Volunteers

United Kingdom
Millennium Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Mass Balance, Pharmacokinetics (PK), Metabolism and Excretion of TAK-954 Containing Microtracer ([14C]-TAK-954) in Healthy Male Participants

Healthy Volunteers

Netherlands
Poxel SA

Completed

Pharmacokinetics and Metabolism of (14C)-Labelled PXL770

Healthy

United Kingdom
argenx

Completed

IV Dose Study to Assess the Safety, Tolerability, PK, PD and Immunogenicity of ARGX-113 in Healthy Volunteers

Healthy Volunteers
PegBio Co., Ltd.

Completed

Continuous Multiple Dose PB-119 Injection in Health Volunteers

Type2 Diabetes Mellitus

China
Sanwa Kagaku Kenkyusho Co., Ltd.

Completed

A Study to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-SK-1405

Pruritus

United Kingdom
ViiV Healthcare
GlaxoSmithKline

Withdrawn

A Study to Investigate the Recovery, Excretion, and Pharmacokinetics of 14C-GSK2248761 Administered as an Oral Suspension to Healthy Adult Subjects

Infection, Human Immunodeficiency Virus

United States
LG Life Sciences

Completed

Study in Healthy Male Subjects Designed to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C] LC15-0444

Healthy

Korea, Republic of
Cardiometabolics

Completed

A Clinical Trial in Higher Risk Geriatric Patients Undergoing OHSP (MiniMetrxics)

Heart Disease

Canada
Umeå University

Unknown

Antibiotic Prophylaxis for Transrectal Prostate Biopsy-Ciprofloxacin vs. Trimethoprim/Sulfamethoxazole

Prostate Infection

Sweden
Sanofi

Completed

Study to Determine Absorption, Metabolism, and Excretion of [14C]-SAR439859, and to Assess Absolute Oral Bioavailability of Amcenestrant (SAR439859), in Healthy Post-menopausal Women

Breast Cancer | Healthy Volunteers

United Kingdom
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

Enpatoran Human Mass Balance and Absolute Bioavailability Study

Healthy

Netherlands
University of Minnesota

Completed

Pilot Study of Meat-Borne Carcinogens and Pancreatic Cancer

Pancreatic Cancer

United States
Ascentage Pharma Group Inc.

Recruiting

A Study Evaluating APG-115 as a Single Agent or in Combination With APG-2575 in Subjects With T-PLL

T-Prolymphocytic Leukemia

United States
argenx

Completed

An Efficacy and Safety Study of ARGX-113 in Patients With Myasthenia Gravis Who Have Generalized Muscle Weakness (ADAPT)

Generalized Myasthenia Gravis

United States, Belgium, Canada, Czechia, Denmark, France, Georgia, Germany, Hungary, Italy, Japan, Netherlands, Poland, Russian Federation, Serbia, United Kingdom
Jazz Pharmaceuticals

Completed

Study Assessing Effects of JZP-110 on Driving Performance in the Treatment of Excessive Sleepiness in OSA

Obstructive Sleep Apnea | Excessive Sleepiness

Netherlands
InQpharm Group

Withdrawn

Vasoactive Effects of IQP-AS-118 in Healthy Individuals

Cardiovascular Disease | Blood Flow

Germany
InQpharm Group

Completed

Benefit of IQP-AS-118 on Blood Pressure and LDL-cholesterol

Blood Pressure | Low Density Lipoprotein Cholesterol Level

Germany
Taiho Pharmaceutical Co., Ltd.

Completed

A Study of TAS-114 in Combination With S-1 in Patients With Advanced Solid Tumors

Advanced Solid Tumors

Japan
Biogen

Completed

Single Ascending Dose Study of the Safety, Tolerability, and Pharmacokinetics of BIIB061 in Healthy Adult Volunteers Including Absolute Bioavailability and Food Effect

Healthy

United States
AstraZeneca

Completed

Study to Assess the Distribution, Metabolism and Excretion of [14C]AZD6765 After a Single-Dose Intravenous Administration (AZD6765)

Major Depressive Disorder

United Kingdom
Lexicon Pharmaceuticals

Completed

An Open-label Study to Evaluate the Absorption, Metabolism, and Excretion of [14C]-Telotristat Etiprate in Males (LX1606-104)

Carcinoid Syndrome

United Kingdom
Hospices Civils de Lyon

Completed

[11C]Yohimbine PET Study of alpha2-AR ([11C]Yohimbine)

Healthy Controls

France
Indonesia University

Recruiting

Administration of Antibiotic Prophylaxis for Transperineal Prostate Biopsy in Cipto Mangunkusumo Hospital

Sepsis | Bacteriuria | Urinary Tract Infections | Prostate Cancer | Perioperative Complication | Prostate Biopsy

Indonesia
59th Medical Wing
Emergency Medicine Foundation

Completed

Prospective Randomized Trial of Bactrim on 7 Day Outcome in Patients With Uncomplicated Abscesses

Abscesses

United States
Protalix

Recruiting

A Study to Evaluate the Safety, Tolerability, PK, and PD Properties of PRX-115 in Adult Volunteers With Elevated Uric Acid Levels

Gout

New Zealand
Mayo Clinic

Not yet recruiting

Nasal Iodine Swab Versus Oral Antibiotic to Prevent Surgical Site Infection After Undergoing Mohs Micrographic Surgery

Skin Cancer | Skin Cancer Face | Malignant Cutaneous Adnexal Neoplasm

United States
Radboud University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Culture-guided Antimicrobial Prophylaxis in Men Undergoing Prostate Biopsy. (pro-SWAP)

Prostate Cancer | Infection | Complication

Netherlands
Pfizer
Forest Laboratories

Completed

Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections)

Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis

Croatia, Bulgaria, Korea, Republic of, Mexico, Peru, Poland, Russian Federation, Spain, Romania, Ukraine, United States, Argentina, Czechia, Israel, Taiwan, Germany, Italy
University Hospital, Geneva

Completed

Randomized Clinical Trial to Compare a Regimen of Trimethoprim-sulfamethoxazole Plus Rifampicin With a Regimen of Linezolid in the Treatment of Methicillin-Resistant Staphylococcus Aureus (MRSA) Infection

MRSA Infection

Switzerland
Jonsson Comprehensive Cancer Center
Merck Sharp & Dohme LLC; Highlight Therapeutics

Terminated

BO-112 and Pembrolizumab for the Treatment of PD-1/PD-L1 Refractory Liver Cancer

Advanced Hepatocellular Carcinoma | BCLC Stage B Hepatocellular Carcinoma | BCLC Stage C Hepatocellular Carcinoma | Refractory Hepatocellular Carcinoma

United States
The Cleveland Clinic
American Urogynecologic Society

Terminated

Prevention of Catheter-Associated Urinary Tract Infection in Incontinence and Reconstructive Pelvic Surgery Patients (PRECAUTION)

Catheter-Associated Urinary Tract Infection

United States
Pfizer

Completed

A Study to Understand How the Study Medicine (PF-07081532) is Processed and Eliminated in Healthy Men

Healthy Participants

Netherlands
Boehringer Ingelheim

Completed

Pharmacokinetics of Talsaclidine After Administration to Healthy Subjects

Healthy
Chang Gung Memorial Hospital
National Science and Technology Council

Not yet recruiting

Hyperpolarized 13C MRI for Cancer Immunotherapy (DNPSPIO)

Cervical Cancer | Gynecologic Cancer | Ovarian Cancer | Endometrial Cancer

Taiwan
Takeda

Completed

Study to Evaluate Absorption, Metabolism, and Excretion, of TAK-994 in 6 Healthy Male Adults

Healthy Volunteers

United States
Theravance Biopharma

Completed

TD-1473 Absorption, Distribution, Metabolism and Excretion (ADME) Study in Healthy Male Subjects

Bowel Diseases, Inflammatory | Intestinal Disorders

United States
PegBio Co., Ltd.
Covance

Completed

Dose-finding of PB-119 Administered Subcutaneously Once Weekly Versus Placebo in Subjects With Type 2 Diabetes

Type 2 Diabetes Mellitus (T2DM)

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Dysregulation of Glutamine Activity in the Pathogenesis of Multiple Myeloma

Monoclonal Gammopathy of Undetermined Significance | Plasma Cell Myeloma

United States
Array Biopharma, now a wholly owned subsidiary...

Completed

A Study of MEK162 and Paclitaxel in Patients With Epithelial Ovarian, Fallopian Tube or Peritoneal Cancer

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Peritoneal Cancer

United States
MRC/UVRI and LSHTM Uganda Research Unit
Medical Research Council

Unknown

Cotrimoxazole Prophylaxis Cessation Study Among Stabilized HIV-Infected Adult Patients on HAART in Entebbe, Uganda (CCS)

HIV Infections

Uganda
59th Medical Wing

Completed

Trial of Antibiotic Treatment for Skin Abscess in Patients at Risk for Methicillin-Resistant Staphylococcus Aureus (MRSA) Infection

Abscess

United States

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