Search clinical trials for: 50 mg AP1189

Total 10822 results

Bial - Portela C S.A.

Completed

Bioavailability and Bioequivalence Between Two Active Pharmaceutical Ingredient (API) Sources of Opicapone (OPC)

Parkinson Disease

United Kingdom
Kremers Urban Development Company
Watson Laboratories, Inc.

Completed

Bioequivalence Study of Bicalutamide 50 mg Tablet and Casodex 50 mg Tablet in Healthy Subjects Under Fasting Conditions

Bioequivalency

Canada
CymaBay Therapeutics, Inc.

Terminated

Study to Evaluate the Effects of Two Doses of MBX-8025 in Subjects With Primary Biliary Cirrhosis (PBC)

Primary Biliary Cirrhosis (PBC)

Germany, United States, Canada, United Kingdom, Poland
Kowa Research Institute, Inc.

Completed

Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of K-312 in Healthy Subjects

Hyperlipidemia

United States
Ache Laboratorios Farmaceuticos S.A.

Terminated

Study to Assess Tolerability, Safety and Pharmacokinetics of a New Drug (ACH15)

Healthy

Brazil
LG Chem

Unknown

Food-effect Bioavailability of Fixed Dose Combination Zemimet® SR Tab. 50/1000 mg Under Fed and Fasting Conditions

Type2 Diabetes
Lexicon Pharmaceuticals

Completed

A Study to Determine the Safety and Efficacy of LX3305 in Subjects With Active Rheumatoid Arthritis

Rheumatoid Arthritis

United States
Biolab Sanus Farmaceutica

Withdrawn

Pharmacokinetics of Eplerenone Tablet

Healthy Volunteers
Janssen Research & Development, LLC

Completed

A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components

Healthy Volunteers

United States
Boehringer Ingelheim

Completed

Relative Bioavailability of Different Formulations of BI 671800 in Healthy Male and Female Volunteers

Healthy
Spanish Clinical Pharmacology Society
Spanish reumatology Society

Completed

Evaluation of a Protocol for Dose Reduction in Patients With Spondylarthropathies and Clinical Remission With Anti-TNF (REDES-TNF)

Spondylarthropathies

Spain
International Bio service

Not yet recruiting

Bioequivalence Study of Diacerein 50 mg Capsule in Healthy Thai Volunteers

Healthy Volunteer
Antios Therapeutics, Inc

Terminated

Ethnobridging Study in Healthy Volunteers, Chinese and Japanese Subjects

Chronic Hepatitis b

United States
IntegoGen, LLC

Withdrawn

Allogeneic Micronized Amniotic Membrane Product for the Treatment of Hidradenitis Suppurativa

Hidradenitis Suppurativa

United States
Merck Sharp & Dohme LLC

Completed

Efficacy and Safety of Elbasvir (MK-8742) + Grazoprevir (MK-5172) in Treatment-Naïve/Treatment-Experienced (TN/TE) French Participants With Hepatitis C Virus (HCV) Genotype 4 (GT4) Infection (MK-5172-096)

Hepatitis C Virus (HCV) Infection

France
Novartis Pharmaceuticals

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of APL180

Coronary Heart Disease

Germany, United States, Denmark, Israel, Netherlands
Novartis Pharmaceuticals

Withdrawn

Effect of APL180 on Endothelial Function in Familial Hypercholesterolemia Patients

Familial Hypercholesterolemia
PHARMENTERPRISES LLC

Completed

Double-blind, Randomized, Placebo-controlled Study of the Safety, Tolerability and Pharmacokinetics of Ascending Doses of XC243 After Single and Multiple Oral Administration in Healthy Volunteers.

Healthy Volunteers

Russian Federation
Boehringer Ingelheim

Completed

This Study is Done in Patients With Plaque Psoriasis and Tests How Well They Tolerate BI 730357 and How Effective it is

Psoriasis

United States, Canada, Germany
Bod Australia
Woolcock Institute of Medical Research

Completed

The CANabidiol Use for RElief of Short Term Insomnia (CANREST)

Insomnia | Sleep Disturbance | Insomnia Type; Sleep Disorder | Insomnia, Transient | Insomnia Due to Anxiety and Fear | Insomnia Due to Other Mental Disorder

Australia
Janssen Research & Development, LLC
GlaxoSmithKline

Completed

Long-term Safety and Efficacy of Sirukumab in Participants With RA Completing Studies CNTO136ARA3002 or CNTO136ARA3003 (SIRROUND-LTE)

Arthritis, Rheumatoid

United States, Poland, Ukraine, United Kingdom, Germany, Taiwan, Mexico, Portugal, Spain, Bulgaria, Malaysia, Romania, Serbia, South Africa, Korea, Republic of, Japan, Canada, Russian Federation, Chile, Puerto Rico, Austria, Argen... and more
Janssen Research & Development, LLC

Completed

A Mass Balance Study With a Microtracer Dose of 14C-esketamine in Healthy Male Participants

Healthy

United States
National Institute of Mental Health (NIMH)
Taisho Pharmaceutical Co., Ltd.

Recruiting

Antidepressant Effects of TS-161 in Treatment-Resistant Depression

Depression | Major Depressive Disorder | Treatment-Resistant Depression

United States
Novartis Pharmaceuticals

Completed

Aliskiren in Combination With Losartan Compared to Losartan on the Regression of Left Ventricular Hypertrophy in Overweight Patients With Essential Hypertension (ALLAY)

Hypertension | Overweight | Left Ventricular Hypertrophy

United States, Finland, Sweden, Germany, Italy, Spain, Argentina, Colombia, Russian Federation
Reata, a wholly owned subsidiary of Biogen

Completed

RTA 408 Capsules in Patients With Melanoma - REVEAL

Melanoma | Unresectable (Stage III) Melanoma | Metastatic (Stage IV) Melanoma

United States
Sadat City University
Beni-Suef University

Completed

Which is Better to Start With DPP-4 Inhibitors or SGLT-2 Inhibitors in Egyptian Diabetic Patients?

Diabete Type 2

Egypt
Empros Pharma AB
CTC Clinical Trial Consultants AB

Completed

A Proof of Concept Trial in Overweight and Obese Patients, Investigating Effect of EMP16-02 on Body Weight (Primary)

Overweight or Obesity

Sweden
Janssen Inc.

Completed

A Study to Evaluate CNTO 1959 in the Treatment of Patients With Moderate to Severe Plaque-type Psoriasis (X-PLORE)

Psoriasis

United States, Poland, Canada, Belgium, Germany
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Hydrochlorothiazide Tablets 50 mg to Hydrochlorothiazide Tablets 50 mg

Healthy

United States
Genuine Research Center, Egypt
Hikma Pharma

Completed

Bioequivalence Study of Solifenacin Succinate & Mirabegron From Mirfenacin MR 5/50 mg Extended Release Tablets (Hikma Pharma, Egypt) Versus Vesicare 5 mg FCT & Betmiga 50 mg Prolonged-Release Tablets (Astellas Pharma Europe B.V, the Netherlands / Astellas Pharma Europe B.V, the Netherlands)

Healthy

Egypt
Mutual Pharmaceutical Company, Inc.

Completed

Fasted Bioequivalence Study of Primidone Tablets and Mysoline Tablets

Therapeutic Equivalency
Merck Sharp & Dohme LLC

Completed

A Study to Demonstrate the Bioequivalence of Sitagliptin/Metformin Combination Tablets and Co-administration of Sitagliptin and Metformin as Individual Tablets (0431A-095)

Type 2 Diabetes
The Lymphoma Academic Research Organisation
Institute of Cancer Research, United Kingdom

Recruiting

Study of Ibrutinib + CD20 Antibody and Venetoclax in Patients With Untreated Mantle Cell Lymphoma

Mantle Cell Lymphoma

France, United Kingdom, Belgium
University of Cape Town
Wellcome Trust; Médecins Sans Frontières, Belgium

Completed

Tenofovir-lamivudine-dolutegravir Combination as Second-line ART: a Randomised Controlled Trial (ARTIST)

HIV Infections

South Africa
Bayer

Completed

Evaluate Analgesic/Sedative Efficacy of Naproxen Sodium and Diphenhydramine in Patients With Postsurgical Dental Pain (Morpheus II)

Pain, Postoperative

United States
Jena University Hospital

Active, not recruiting

Pentaerithrityl Tetranitrate (PETN) for Secondary Prevention of Intrauterine Growth Restriction (PETN)

Pregnancy Related | Fetal Growth Retardation | Intrauterine Growth Restriction

Germany
Johns Hopkins University
National Heart, Lung, and Blood Institute (NHLBI); American Lung Association

Completed

Pilot of Zinc Acetate to Improve Chronic Cough (ZICO)

Cough

United States
University of Saskatchewan

Recruiting

Evaluation of 89Zr-DFO-nimotuzumab for Non-invasive Imaging of EGFR+ Cancers by Positron Emission Tomography (PET)

Colorectal Cancer | Lung Cancer

Canada
Janssen Research & Development, LLC

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-42165279 in Healthy Young and Elderly Participants

Healthy

Belgium
Rare Disease Research, LLC
Sarepta Therapeutics, Inc.

Terminated

An Open-Label Study of Golodirsen in Non-Ambulant Patients With Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy

United States
University of Cape Town
Wellcome Trust; Medecins Sans Frontieres, Netherlands

Completed

Standard Versus Double Dose Dolutegravir in Patients With HIV-associated Tuberculosis (RADIANT-TB)

HIV Infections | Tuberculosis

South Africa
Novartis

Completed

Efficacy of add-on Therapy With Vildagliptin in Chinese Patients With Type 2 Diabetes Inadequately Controlled With Prior Metformin Monotherapy

Type 2 Diabetes Mellitus

China
Lyndra Inc.

Terminated

Study Determining Gastric-Retentive and Modified Release Properties of Prototype Capsules in Healthy Subjects

Healthy | Gastric Retention

United Kingdom
Otsuka Pharmaceutical Development & Commercialization...

Completed

Pharmacokinetic and Safety Trial to Determine the Appropriate Dose for Pediatric Patients With Multidrug Resistant Tuberculosis

Pediatric | Multidrug Resistant Tuberculosis

Philippines, South Africa
Shanghai Public Health Clinical Center

Not yet recruiting

Efficacy and Tolerability of DTG Plus 3TC in HIV Infected Adults With Virologically Suppression and TDF Toxicity

Acquired Immunodeficiency Syndrome
Reseach Laboratory of Clinical and Experimental...
Société Arabe des Industries Pharmaceutiques SAIPH - Tunisia; Centre National...

Completed

Bioequivalence Study to Compare Metformin / Vildagliptin (850 mg/50 mg) Versus Galvumet®

Fed Conditions

Tunisia
Ain Shams University
Drug Research Centre, Cairo, Egypt

Completed

A Comparative Pharmacokinetic and Pharmacodynamic Study of Sildenafil in Adult Smokers and Non Smokers

Smoking | Erectile Dysfunction | Pharmacokinetics | Pharmacodynamics

Egypt
Stendhal Americas, S.A.
LG Chem; Universidad Nacional Autonoma de Mexico

Completed

An Assessment of Pharmacokinetic Gemigliptin and Metformin Interactions in Healthy Mexican Volunteers

Diabetes Mellitus, Type 2

Mexico
Janssen Research & Development, LLC

Terminated

A Study to Investigate Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-64140284 in Healthy Participants

Healthy

Belgium
University of Alberta

Recruiting

The Impact of Sildenafil on the Pulmonary Circulation in Healthy Trained and Untrained Humans

Healthy

Canada

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