Search clinical trials for: A randomized controlled open-label clinical trial.

Total 191 results

Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

A Study of SHR-A1811 in First-line Treatment of Patients With Advanced or Metastatic Non-small Cell Lung Cancer With HER2 Mutations

Non-Small Cell Lung Cancer With HER2- Mutations

China
Janssen Research & Development, LLC

Recruiting

A Study of Lazertinib as Monotherapy or in Combination With Amivantamab in Participants With Advanced Non-small Cell Lung Cancer (Chrysalis-2)

Carcinoma, Non-Small-Cell Lung

Taiwan, United States, Korea, Republic of, Germany, France, China, Japan, Italy, Spain, Puerto Rico
Henry Ford Health System
Pfizer

Terminated

Pregabalin for Abdominal Pain From Adhesions

Abdominal Pain | Surgical Adhesions

United States
Pfizer

Active, not recruiting

Continued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are Closing

Ovarian Cancer | NSCLC | Solid Tumors | Urothelial Cancer | Advanced Malignancies

Hungary, Spain, United States, Canada, Taiwan, Japan, Serbia, Italy, New Zealand, Australia, Mexico, Russian Federation, United Kingdom, France, Korea, Republic of, Belgium, Poland, Denmark, Israel
Janssen Research & Development, LLC

Active, not recruiting

A Study of Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy Compared With Platinum-Based Chemotherapy in Patients With Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non- Small Cell Lung Cancer After Osimertinib Failure (MARIPOSA-2)

Carcinoma, Non-Small-Cell Lung

Canada, Germany, Italy, China, Belgium, United States, Taiwan, Israel, United Kingdom, Korea, Republic of, Sweden, Japan, Poland, Malaysia, Netherlands, Spain, Turkey, France, India, Mexico, Argentina, Brazil, Portugal, Russian Federation and more
Cheng-Chia (Fred) Wu
Focused Ultrasound Foundation

Active, not recruiting

FUS Etoposide for DMG

Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant

United States
AstraZeneca

Completed

Efficacy and Safety Study of Benralizumab for Patients With Severe Nasal Polyposis (OSTRO)

Nasal Polyposis

United States, Canada, Denmark, Belgium, Germany, Hungary, Austria, Poland
Joseph Tuscano
Millennium Pharmaceuticals, Inc.

Completed

Bortezomib and Doxil for the Treatment of Patients With Acute Myelogenous Leukemia

Acute Myelogenous Leukemia

United States
Johannes Kepler University of Linz

Recruiting

Personalized Therapy of Patients Suffering From Rare Genodermatoses

Rare Diseases

Austria
Guangxi Medical University

Unknown

Adjuvant Therapies for Patients With HCC and MVI (A-TACE/S-HCC)

Hepatocellular Carcinoma

China
Cambridge Health Alliance

Completed

Efficacy of N-Acetylcysteine (NAC) in Preventing COVID-19 From Progressing to Severe Disease

COVID | Oxidative Stress | Sars-CoV2 | SARS-Associated Coronavirus as Cause of Disease Classified Elsewhere

United States
Shenzhen People's Hospital

Not yet recruiting

Clinical Study of Clevidipine Butyrate Injection in the Treatment of Hypertensive Emergency and Sub-emergency

Hypertensive Emergency

China
Medical University of Vienna

Completed

Concentration of Ampicillin / Sulbactam and Amoxicillin / Clavulanic Acid in the Blood During Renal Replacement Therapy in Longterm Renal Replacement Therapy Patients

Infection During Hemodialysis

Austria
National Cancer Institute (NCI)

Terminated

RO4929097 and Erlotinib Hydrochloride in Treating Patients With Stage IV or Recurrent Non-small Cell Lung Cancer

Recurrent Non-Small Cell Lung Carcinoma | Stage IV Non-Small Cell Lung Cancer

United States
Shandong Cancer Hospital and Institute

Unknown

Sorafenib Combined With Transarterial Chemoembolization in Treating HBV-infected Patients With Intermediate Hepatocellular Carcinoma

Liver Diseases | Neoplasms by Histologic Type | Neoplasms by Site | Adenocarcinoma | Carcinoma | Neoplasms, Glandular and Epithelial | Digestive System Neoplasms | Carcinoma, Hepatocellular | Liver Neoplasms | HBV | PHENYTOIN/SORAFENIB [VA Drug Interaction] | DOXORUBICIN/TRASTUZUMAB [VA Drug Interaction]

China
Croma-Pharma GmbH

Completed

Botulinum Toxin Treatment of Glabellar Lines: Efficacy and Safety Study II (BLESS-II)

Glabellar Frown Lines
Bristol-Myers Squibb

Completed

Study to Assess Safety and Effectiveness of Branebrutinib Treatment in Participants With Active Systemic Lupus Erythematosus or Primary Sjögren's Syndrome, or Branebrutinib Treatment Followed by Open-label Abatacept Treatment in Study Participants With Active Rheumatoid Arthritis

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Autoimmune Disorder | Primary Sjögren's Syndrome

United States, Argentina, Belgium, France, Germany, Mexico, Poland, Spain, Netherlands, United Kingdom
University of Pennsylvania
Abbott

Completed

The Fenofibrate and Metformin for Atherogenic Dyslipidemia (FAMA) Study

Metabolic Syndrome x

United States
University of Concepcion, Chile
Comisión Nacional de Investigación Científica y Tecnológica

Completed

Evaluation of N-Acetylcysteine Efficacy to Reduce the Craving and to Prolong Abstinence Time of Coca Paste (NAC-PBC)

Cocaine-Related Disorders

Chile
Regeneron Pharmaceuticals

Recruiting

A Trial to Learn How the Combination of Fianlimab With Cemiplimab and Chemotherapy Works Compared With Cemiplimab and Chemotherapy for Treating Adult Patients With Advanced Non-small Cell Lung Cancer

Non-small Cell Lung Cancer

Korea, Republic of, United States, Malaysia, Australia, Georgia, Israel, Canada
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

Intranasal Dexmedetomidine for Severe Dental Anxiety: a Randomized Trial

Dental Anxiety
Sichuan University

Recruiting

Safety and Efficacy of Whole Brain LDRT+ICI+Intrathecal Chemotherapy in Refractory Meningeal Metastasis of Lung Cancer

NSCLC | PD-1 Inhibitor | Leptomeningeal Metastasis | Low Dose Radiotherapy

China
Assiut University

Not yet recruiting

Effect of IV Nalbuphine on Nausea and Vomiting Following Intrathecal Morphine

Inguinal Hernia
University of Pennsylvania
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Dopamine Receptor Imaging to Predict Response to Stimulant Therapy in Chronic TBI (DAPET-TBI)

Traumatic Brain Injury | Attention Deficit Disorder | Cognition Disorder

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Completed

Cetuximab, Cisplatin, Fluorouracil, and Radiation Therapy in Treating Patients With Anal Cancer

Anal Cancer

United States
University Hospital, Basel, Switzerland
Triemli Hospital

Completed

Influence of Epidural Analgesia in Elective Laparoscopic Colorectal Resections

Pain

Switzerland
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Ph II Gemcitabine, Erlotinib, and Gemcitabine With Erlotinib/Elderly Patients W/ IIIB/IV NSCLC

Lung Cancer

United States
University of Iowa
National Institute of Nursing Research (NINR)

Completed

Listening Visits for Emotionally Distressed Mothers of Hospitalized Newborns

Emotional Distress | Nurse Delivered Counseling

United States
Janssen Research & Development, LLC

Active, not recruiting

Study of Amivantamab, a Human Bispecific EGFR and cMet Antibody, in Participants With Advanced Non-Small Cell Lung Cancer (CHRYSALIS)

Non-Small-Cell Lung Cancer

United States, France, Taiwan, United Kingdom, China, Spain, Japan, Australia, Korea, Republic of, Canada
Merck Sharp & Dohme LLC

Recruiting

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

Non Small Cell Lung Cancer

United States, Israel, Taiwan, Korea, Republic of, Switzerland
Institute of Hematology & Blood Diseases Hospital...

Recruiting

A Study of VRD-based Regimen Combined With CART-ASCT-CART2 Treatment in Patients With Primary Plasma Cell Leukemia

Plasma Cell Leukemia

China
Dutch Society of Physicians for Pulmonology and...

Completed

Paclitaxel-Carboplatin-Bevacizumab +/- Nitroglycerin in Metastatic Non-Squamous-Non-Small Cell Lung Cancer (NVALT12)

Non Small Cell Lung Cancer

Netherlands
Hadassah Medical Organization

Completed

A Protocol for the Use of Chlorhexidine Gluconate Saturation for the Reduction of Dental Biofilm Formation on Polymethylmethacrylate Restoration

Dental Plaque

Israel
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Completed

Gemcitabine Hydrochloride, Oxaliplatin, and Erlotinib Hydrochloride in Treating Patients With Advanced Biliary Tract Cancer, Pancreatic Cancer, Duodenal Cancer, or Ampullary Cancer

Pancreatic Cancer | Small Intestine Cancer | Liver Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer | Periampullary Adenocarcinoma

United States
Alcon Research

Completed

Patient Preference Comparison of AZARGA Versus COSOPT in Patients With Glaucoma

Glaucoma

Argentina
UNC Lineberger Comprehensive Cancer Center

Terminated

18-FLT PET/MR Imaging to Predict Graft Failure and GVHD in Bone Marrow Transplant Patients

Graft Vs Host Disease

United States
Pontificia Universidad Catolica de Chile

Completed

Premedication With Simethicone or Simethicone Plus N-acetylcysteine in Improving Visibility During Upper Endoscopy (PRUE)

Stomach Neoplasms

Chile
R-Pharm

Terminated

A Study of Ixabepilone as Second-line Therapy for Locally Advanced, Recurrent, or Metastatic Endometrial Cancer (IXAMPLE2)

Endometrial Cancer

Brazil, Czech Republic, Italy, Mexico, Russian Federation, Sweden, United Kingdom, United States, Spain, Canada, Denmark, France, Peru, Belgium, Hungary, Norway, Argentina, Australia, Greece
Federal University of Minas Gerais

Completed

A Randomized Trial of Carvedilol in Chronic Chagas Cardiomyopathy

Heart Failure | Chagas Cardiomyopathy | Dilated Cardiomyopathy

Brazil
Duke University
The Emmes Company, LLC

Completed

Long-term Antipsychotic Pediatric Safety Trial (LAPS)

Weight, Body

United States
Herbert Irving Comprehensive Cancer Center
National Cancer Institute (NCI)

Unknown

Doxorubicin Hydrochloride Liposome, Melphalan, and Bortezomib in Treating Patients With Relapsed or Refractory Stage I, Stage II, or Stage III Multiple Myeloma

Multiple Myeloma and Plasma Cell Neoplasm

United States
Duke University

Completed

Splanchnic Nerve Anesthesia in Heart Failure

Heart Failure

United States
St. Louis University

Completed

A Cost Effective Treatment for Headache in Pregnancy When Acetaminophen Alone is Ineffective. (MAD)

Headache

United States
Janssen Research & Development, LLC

Recruiting

A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer (PALOMA-2)

Carcinoma, Non-small-Cell Lung

United States, Korea, Republic of, Italy, Israel, Malaysia, United Kingdom, China, Brazil, Spain, Germany, Japan, France
AstraZeneca

Active, not recruiting

Study of Durvalumab With Tremelimumab Versus SoC as 1st Line Therapy in Metastatic Non Small-Cell Lung Cancer (NSCLC) (NEPTUNE) (NEPTUNE)

Non Small Cell Lung Carcinoma NSCLC

Denmark, United Kingdom, United States, Poland, Brazil, India, Japan, Mexico, Peru, Russian Federation, Turkey, China, Malaysia, Hong Kong, Korea, Republic of, Chile, Israel, Ukraine, Portugal, Greece, Bulgaria, Philippines, Sweden, A... and more
National Cancer Institute (NCI)

Completed

Erlotinib Hydrochloride With or Without Carboplatin and Paclitaxel in Treating Patients With Stage III-IV Non-small Cell Lung Cancer

Lung Adenocarcinoma | Minimally Invasive Lung Adenocarcinoma | Malignant Pleural Effusion | Stage IIIB Lung Non-Small Cell Cancer AJCC v7 | Stage IV Lung Non-Small Cell Cancer AJCC v7 | Malignant Pericardial Effusion | Lung Adenosquamous Carcinoma

United States
Northwestern University

Terminated

Analgesic Effect of Perioperative Systemic Lidocaine in Patients Undergoing Unilateral Mastectomy Surgery

Pain
China Medical University Hospital

Completed

Anti-histamines Promote Electroacupuncture Analgesia: Basic and Clinical Research

Pain

Taiwan
Hospital Universitari de Bellvitge

Terminated

To Evaluate Reduction of Pain in Wounds Treatment Previously Applying Lidocaine Topical Solution vs Placebo

Local Anesthesia | Wounds

Spain
Azidus Brasil

Suspended

Effectiveness of Association Mometasone Furoate 0.1% and Salicylic Acid 5% Compared With Mometasone Furoate (Psoriasis)

Plaque Psoriasis

Search clinical trials for: A randomized controlled open-label clinical trial.

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