Search clinical trials for: ACE-2494 or placebo

Total 1154 results

Arthrex, Inc.

Completed

Autologous Conditioned Plasma (ACP) Intra-articular (IA) Injections for Knee Osteoarthritis (OA)

Osteoarthritis

United States
Kubota Vision Inc.
Otsuka Pharmaceutical Co., Ltd.

Completed

Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ACU-4429 in Subjects With Geographic Atrophy

Geographic Atrophy | Dry Age-related Macular Degeneration

United States
Biotest

Completed

Safety and Efficacy of Multiple Doses of BT061 in Patients With Moderate to Severe Chronic Plaque Psoriasis

Psoriasis Vulgaris

Czech Republic, Hungary
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

A Study of Multiple Doses of ALXN2050 in Healthy Adults

Healthy

New Zealand
Acceleron Pharma, Inc., a wholly-owned subsidiary...

Recruiting

A Study of Sotatercept for the Treatment of Cpc-PH Due to HFpEF (MK-7962-007/A011-16) (CADENCE)

Hypertension, Pulmonary

United States, Belgium, France, Germany, Israel, Italy, Spain, Sweden, United Kingdom, Poland, Canada
Idorsia Pharmaceuticals Ltd.

Completed

Study to Investigate the Tolerability, Safety, Pharmacokinetics, and Pharmacodynamics of ACT-389949

Healthy Subjects

Netherlands
Xinnate AB
Region Skane

Completed

Safety, Tolerability, and Pharmacokinetics of Ascending Topical Doses of TCP-25 Applied to Epidermal Suction Blister Wounds, Non-Healing Leg Ulcers and Patients With Dystrophic Epidermolysis Bullosa.

Blister | Epidermolysis Bullosa | Wound of Skin | Varicose Ulcer of Lower Limb

Sweden
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

A Study of Single-dose ALXN2050 in Healthy Adults

Healthy

New Zealand
University of Cincinnati

Active, not recruiting

Early Intervention in Cognitive Aging

Overweight, Obesity and Other Hyperalimentation (E65-E68)

United States
Acceleron Pharma Inc. (a wholly owned subsidiary...

Completed

A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (PAH) (PULSAR)

Pulmonary Arterial Hypertension

Spain, United States, Israel, Australia, Germany, United Kingdom, France, Brazil
H. Lundbeck A/S

Completed

Study Investigating the Safety, Tolerability, and Pharmacokinetic Properties of Lu AE58054 in Healthy Japanese and Caucasian Subjects

Healthy

United Kingdom
Grand Medical Pty Ltd.
Grand Pharmaceutical (China) Co., Ltd.

Recruiting

A Study to Evaluate the Safety and Effect of STC314 Injection Continuous Infusion in Subjects With Acute Respiratory Distress Syndrome

Acute Respiratory Distress Syndrome

China
Alexion Pharmaceuticals

Completed

Study of ALXN2050 in Healthy Adult Participants of Japanese Descent

Healthy

United States
Idorsia Pharmaceuticals Ltd.

Completed

Single Oral Dose of 4 mg Cenerimod in Healthy Japanese and Caucasian Subjects

Healthy Volunteers

United States
Children's Hospital of Philadelphia

Completed

Obstructive Sleep Apnea and Neurocognitive and Cardiovascular Function in Children With Down Syndrome (TRIO)

Obstructive Sleep Apnea Syndrome | Down Syndrome

United States
University Hospital, Ghent

Completed

Pathophysiological Mechanisms of Hepatopulmonary Influence in the Fontan Circulation

Children With a Univentricular Heart Undergoing Surgery for Creation of a Fontan Circulation

Belgium
Midnight Pharma, LLC

Completed

Almorexant (ACT-078573) in Elderly Subjects With Chronic Primary Insomnia

Chronic Primary Insomnia

United States
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Assess the Tolerability, Safety, Pharmacodynamics, and Pharmacokinetics of Ascending Single Doses (Including Food Interaction) and Ascending Multiple Doses of ACT-453859, and Multiple Doses of Setipiprant (ACT-129968)

Healthy
HeNan Sincere Biotech Co., Ltd

Completed

A Study of CL-197 Capsules in Healthy Participants

HIV-1

China
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Examine the Safety, Tolerability, and Pharmacokinetics of Single- and Multiple-ascending Doses of ACT-777991 in Healthy Subjects

Healthy

Netherlands
Shanghai Hengrui Pharmaceutical Co., Ltd.

Not yet recruiting

A STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF MULTIPLE SUBCUTANEOUS INJECTIONS OF SHR-1819 IN PATIENTS WITH MODERATE TO SEVERE ATOPIC DERMATITIS

Moderate to Severe Atopic Dermatitis
Guangdong Hengrui Pharmaceutical Co., Ltd

Enrolling by invitation

Safety and Tolerance of Increased Doses of SHR-2106 Injection in Healthy Subjects

Kidney Transplantation

China
University Hospital, Bonn

Active, not recruiting

An Exploratory Clinical Study on Autophagy and Multi-level Molecular Profiling During Spermidine Supplementation

Depression | Healthy

Germany
Alzheon Inc.
Quotient Clinical

Completed

Multiple Ascending Dose Study of ALZ-801

Alzheimer Disease

United Kingdom
Neurogen Corporation

Terminated

Efficacy and Safety Study of Aplindore in Patients With Early Parkinson Disease

Early Parkinson Disease

United States
Shandong Suncadia Medicine Co., Ltd.

Active, not recruiting

Safety and Tolerance of Increased Doses of HRS-1780 Tablets in Healthy Subjects

Chronic Kidney Disease

China
Bridge Biotherapeutics, Inc.
Covance

Completed

Efficacy and Safety of Orally Administered BBT-401-1S in Subjects With Ulcerative Colitis

Ulcerative Colitis

United States, Korea, Republic of, Poland, Ukraine
7TM Pharma A/S

Terminated

A Study to Determine the Effects of TM30339 on Weight Loss in Obese Individuals.

Obesity
Vertex Pharmaceuticals Incorporated

Completed

Study of VX-985 in Subjects With Chronic Hepatitis C

Chronic Hepatitis C

United States
Neurogen Corporation

Terminated

Efficacy and Safety Study of Aplindore in Patients With Restless Legs Syndrome

Restless Legs Syndrome

United States
University Hospital, Strasbourg, France

Unknown

Arteriopathy and Endothelial Function

Peripheral Arterial Disease

France
Ionis Pharmaceuticals, Inc.

Completed

Safety, Tolerability, and Pharmacodynamic Study of ISIS CRP Rx in Rheumatoid Arthritis

Rheumatoid Arthritis

Canada, Russian Federation
University of South Florida

Completed

Repeated Nasal Challenge in Skin Prick-puncture Negative and Intradermal Positive Dust Mite Allergic Rhinitis Patients (DUSTMITE)

ALLERGIC RHINITIS

United States
University Hospital, Ghent

Completed

A Trial Investigating the Effect of a Treatment With Zinkgluconaat for Verrucae Vulgares

Verrucae Vulgares

Belgium
Takeda

Completed

Single-Dose Study of MT203

Healthy Volunteers

Japan
Alexion Pharmaceuticals, Inc.

Terminated

Study of ALXN2050 in Adult Participants With Generalized Myasthenia Gravis

Generalized Myasthenia Gravis | Myasthenia Gravis

United States, Italy, Spain, Canada, Germany, Korea, Republic of, Serbia, Taiwan
Kubota Vision Inc.
Otsuka Pharmaceutical Co., Ltd.

Completed

Safety and Efficacy Assessment Treatment Trials of Emixustat Hydrochloride (SEATTLE)

Geographic Atrophy

United States
Kubota Vision Inc.
Otsuka Pharmaceutical Co., Ltd.

Completed

Safety and Tolerability of Repeat Doses of ACU-4429 in Healthy Subjects

Healthy

United States
Evolve BioSystems, Inc.

Terminated

The COLIC Study: Colonization of the Infant Gut With B. Infantis EVC001 to Reduce Symptoms of Colic (COLIC)

Infantile Colic

United States
Idorsia Pharmaceuticals Ltd.

Completed

Single-ascending Dose Study to Investigate the Tolerability, Safety, Pharmacokinetics, and Pharmacodynamics of ACT-462206

Pharmacokinetics | Pharmacodynamics | Tolerability | Safety

Netherlands
University of British Columbia
University of Pennsylvania; Wuhan University; Canadian Institutes of Health Research... and other collaborators

Unknown

Host Response Mediators in Coronavirus (COVID-19) Infection (ARBS CORONA I)

COVID-19 | SARS-CoV2

Canada
IRCCS Centro San Giovanni di Dio Fatebenefratelli
IRCCS San Raffaele; Fondazione Don Carlo Gnocchi Onlus; IRCCS Centro Neurolesi...

Active, not recruiting

Telerehabilitation in Mild Cognitive Impairment

Mild Cognitive Impairment

Italy
An-Najah National University

Recruiting

Continuing or Discontinuing ACE/ARBs in Patients With Chronic Kidney Disease Undergoing Coronary Angiography

Chronic Kidney Diseases | Ischemic Heart Disease | Contrast-induced Nephropathy

Palestinian Territory, occupied
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

The Mechanism of Vaginal Flora and Its Metabolites in the Pathogenesis of Cervical Cancer

Cervical Cancer

China
Boston Pharmaceuticals

Completed

Study to Determine the Relative Bioavailability, Single and Repeat Dose Pharmacokinetics, Safety and Tolerability of BOS172767 Enantiomers in Healthy Subjects

Healthy Participants

United Kingdom
Akros Pharma Inc.

Terminated

Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Oral Doses of JTT-252

Diabetes Mellitus

United States
Hellenic Institute for the Study of Sepsis

Completed

The Benefit of Bermekimab in Patients With Systemic Sclerosis

Scleroderma, Systemic

Greece
Pfizer

Completed

A Study to Evaluate Safety and Efficacy of PF-06826647 For Moderate To Severe Plaque Psoriasis

Psoriasis

Canada, United States, Japan, Poland
Nathaniel Jenkins

Completed

Energy Drink Effects on Performance, Mood, and Cardiovascular Outcomes

Mood | Caffeine | Exercise Performance | Energy Drink | Cardiovascular Safety

United States
University of Maryland, Baltimore
National Center for Complementary and Integrative Health (NCCIH)

Terminated

Safety of VSL#3 in Adult Asthmatics

Asthma

United States

Search clinical trials for: ACE-2494 or placebo

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Bahrain

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations