Search clinical trials for: ALS-L1023

Total 256296 results

AngioLab, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of ALS-L1023 in Subjects With NASH

Nonalcoholic Steatohepatitis

Korea, Republic of
Hanmi Pharmaceutical Company Limited

Terminated

Efficacy and Safety Study of ALS-L1023 in Patients With Abdominal Obesity of Metabolic Syndrome

Abdominal Obesity Metabolic Syndrome

Korea, Republic of
Rocket Pharmaceuticals Inc.

Unknown

A Clinical Trial to Evaluate the Safety of RP-L102 in Pediatric Subjects With Fanconi Anemia Subtype A

Fanconi Anemia Complementation Group A

United States
Melior Pharmaceuticals
Bukwang Pharmaceutical, Co., Ltd.

Completed

Adult Subjects With Uncontrolled Type 2 Diabetes

Type 2 Diabetes

United States
Rocket Pharmaceuticals Inc.

Active, not recruiting

Lentiviral-mediated Gene Therapy for Pediatric Patients With Fanconi Anemia Subtype A

Fanconi Anemia Complementation Group A

Spain, United Kingdom
Rocket Pharmaceuticals Inc.

Active, not recruiting

Gene Therapy for Fanconi Anemia, Complementation Group A

Fanconi Anemia Complementation Group A

United States
Biotie Therapies Corp.

Completed

BTT-1023 in Rheumatoid Arthritis

Rheumatoid Arthritis

Bulgaria
Melior Pharmaceuticals
Bukwang Pharmaceutical, Co., Ltd.

Unknown

An Add-on Study of MLR-1023 in Adults With Uncontrolled Type 2 Diabetes on Metformin Therapy

Type 2 Diabetes Mellitus

United States
AngioLab, Inc.

Completed

Evaluation of the Safety and Efficacy of ALS-L1023 Administered in Combination With Ranibizumab in Patients With Wet-AMD

Age-Related Macular Degeneration

Korea, Republic of
Janssen Research & Development, LLC

Completed

Study to Assess the Taste Profile of Different ALS-008176 Oral Liquid Formulations in Healthy Adult Participants

Healthy

United Kingdom
Alios Biopharma Inc.

Completed

A Phase 2a Study to Evaluate ALS-008176 in the Virus Challenge Model

Respiratory Syncytial Virus Infections

United Kingdom
Johann Wolfgang Goethe University Hospital

Unknown

Intraoperative MRI and 5-ALA Guidance to Improve the Extent of Resection in Brain Tumor Surgery (IMAGER)

Glioma | Glioblastoma | Primary Malignant Neoplasm of Nervous System | Metastasis

Germany
Janssen Research & Development, LLC

Terminated

A Study to Evaluate the Antiviral Activity, Clinical Outcomes, Safety, Tolerability, and Pharmacokinetics of Orally Administered Lumicitabine (JNJ-64041575) Regimens in Hospitalized Infants and Children Aged 28 Days to 36 Months Infected With Respiratory Syncytial Virus

Respiratory Syncytial Viruses

United States, Belgium, Canada, Hungary, Japan, Poland
Janssen Research & Development, LLC

Withdrawn

Antiviral Activity, Clinical Outcomes, Safety, Tolerability, and Pharmacokinetics of Oral Lumicitabine Regimens in Hospitalized Adult Participants Infected With Human Metapneumovirus (STEP)

Metapneumovirus

Netherlands, United States, France, Taiwan, Korea, Republic of, Australia, Japan, Spain, Malaysia, Russian Federation, Sweden, Poland, Bulgaria, Argentina, Brazil, Ukraine
Janssen Research & Development, LLC

Terminated

Study to Evaluate the Antiviral Activity, Clinical Outcomes, Safety, Tolerability, and Pharmacokinetics of Orally Administered Lumicitabine Regimens in Adult Participants Hospitalized With Respiratory Syncytial Virus

Respiratory Syncytial Viruses

Australia, France, United Kingdom, Belgium, Taiwan, United States, Spain, Argentina, Mexico, Bulgaria, Malaysia, Japan, Sweden, Korea, Republic of, Canada, Netherlands, Brazil, Germany, Poland
Alios Biopharma Inc.

Completed

A Study of Orally Administered JNJ-440 to Evaluate the Safety, Tolerability, and Pharmacokinetics After Single Ascending Doses Including Food Effect Evaluation; After Multi-Day Dosing in Healthy Participants; and After Multiple (Ascending) Doses in Participants With Chronic Hepatitis B

Chronic Hepatitis B

Korea, Republic of, Moldova, Republic of, New Zealand, Thailand, Ukraine
National Institute of Allergy and Infectious Diseases...

Completed

Safety and Immunogenicity of a First-in-Human Mosquito Saliva Peptide Vaccine

Mosquito-Borne Disease

United States
Allegro Ophthalmics, LLC

Completed

A Safety And Efficacy Study Of ALG-1001 In Human Subjects With Wet Age-Related Macular Degeneration

Macular Degeneration

Mexico
Astellas Pharma Inc
Agensys, Inc.

Completed

AGS-1C4D4 in Patients With Advanced Hormone Refractory Prostate Cancer

Prostate Cancer

United States
Sun Yat-sen University

Recruiting

Serum Estradiol (E2) Levels in Breast Cancer Patients During Endocrine Therapy by High Performance Liquid Chromatography-tandem Mass Spectrometry (LC-MS /MS)

Breast Cancer

China
The University of Hong Kong

Completed

Volatility and Heterogeneity of Vaccine Sentiments Means Continuous Monitoring is Needed When Measuring Message Effectiveness

Vaccine-Preventable Diseases | Vaccine Refusal

Hong Kong
University Medical Center Groningen
PRA Health Sciences; TRACER Europe BV

Recruiting

Anti-COVID19 VaccinaTion AKS-452 BOOSTER (ACT-BOOSTER Study) (ACT-BOOSTER)

COVID-19

Netherlands
University Medical Center Groningen
Akston Biosciences Corporation

Completed

Anti-COVID19 AKS-452 Fusion Protein Vaccine - ACT Study (ACT)

Covid19

Netherlands
Assiut University

Unknown

Antiphospholipid Antibodies & Osteopontin as Risk Factors for Cerebrovascular Stroke in Young Adults

Stroke in Young Adults

Egypt
Aqualung Therapeutics Corp.

Not yet recruiting

Study of Safety and Efficacy of ALT-100mAb in Participants With Moderate/Severe ARDS

Acute Respiratory Distress Syndrome (ARDS)
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co...

Completed

Pharmacokinetics and Safety of ALA in Acne Vulgaris

Acne Vulgaris

China
Zimmer Biomet
Biomet Biologics, LLC

Completed

Safety of NStride Autologous Protein Solution in the Treatment of Knee Osteoarthritis (PROGRESS I)

Osteoarthritis, Knee

United States
Zimmer Biomet

Completed

Prospective Post-Market Data Collection on Patients With Knee OA and Treated With nSTRIDE APS (PROGRESS III)

Osteoarthritis, Knee

United Kingdom
Alnylam Pharmaceuticals

Completed

Dose Escalation Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Intravenous ALN-VSP02 In Patients With Advanced Solid Tumors With Liver Involvement

Solid Tumors

United States, Spain
Alnylam Pharmaceuticals

Terminated

A Study to Evaluate ALN-XDH in Healthy Subjects and Patients With Gout

Gout

United Kingdom
Alnylam Pharmaceuticals

Completed

Multi-center, Open Label, Extension Study of ALN-VSP02 in Cancer Patients Who Have Responded to ALN-VSP02 Treatment

Solid Tumors

United States, Spain
Institut d'Investigació Biomèdica de Bellvitge

Recruiting

Infectious Diseases Experts as Part of the Antibiotic Stewardship Team in Primary Care (IDASP)

Infectious Disease

Spain
Regeneron Pharmaceuticals

Not yet recruiting

A Trial to Learn if Receiving ALN-PNP siRNA is Safe and Well Tolerated, and How it Works in Adult Participants With Nonalcoholic Fatty Liver Disease (NAFLD) and a Genetic Risk Factor

Nonalcoholic Steatohepatitis (NASH) | Nonalcoholic Fatty Liver Disease (NAFLD) | Genetic Risk Factor
Alnylam Pharmaceuticals

Terminated

A Study of ALN-HSD in Healthy Adult Subjects and Adult Patients With Nonalcoholic Steatohepatitis (NASH)

Nonalcoholic Steatohepatitis | NASH

United States, Bulgaria, United Kingdom, Belgium, Turkey
Alnylam Pharmaceuticals

Terminated

A Study of Cemdisiran in Adults With Immunoglobulin A Nephropathy (IgAN)

IgA Nephropathy (IgAN) | Berger Disease | Glomerulonephritis, IgA

Canada, Malaysia, France, Sweden, United Kingdom, Philippines, Singapore, Spain, Taiwan
Zimmer Biomet

Completed

APSS-33-00: A Multicenter, Pilot Study of Autologous Protein Solution (APS) in Knee Osteoarthritis (OA) (PROGRESS II)

Osteoarthritis, Knee

Italy, Austria, Belgium, Norway
Synvista Therapeutics, Inc

Completed

The SAPPHIRE Study (Systolic And Pulse Pressure Hemodynamic Improvement By Restoring Elasticity)

Hypertension
Alios Biopharma Inc.

Completed

A Phase 1, Open-Label Study of the Absorption, Metabolism, Excretion and Absolute Bioavailability of ALS-008176

Respiratory Syncytial Virus Infections

United Kingdom
Regeneron Pharmaceuticals

Recruiting

A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Non-Alcoholic Steatohepatitis (NASH) in Adult Participants at Increased Genetic Risk for This Condition (NASHGEN-2)

Non-alcoholic Steatohepatitis (NASH) | Metabolic Dysfunction Associated Steatohepatitis (MASH)

United States, Korea, Republic of, Puerto Rico, Japan
Jan Frystyk

Recruiting

Cross-sectional Study of 1200 Recreational Athletes With Former or Current Use of Androgenic Anabolic Steroids (FIDODK/BIC)

Heart Failure | Cardiovascular Morbidity | Androgen Deficiency

Denmark
Fox Chase Cancer Center

Recruiting

Phase I Study in Advanced Malignancies With 5-ALA

Solid Tumor

United States
Alnylam Pharmaceuticals

Terminated

A Study of ALN-AAT02 in Healthy Participants and Participants With ZZ Type Alpha-1 Antitrypsin Deficiency Liver Disease

ZZ Type Alpha-1 Antitrypsin Deficiency Liver Disease

United Kingdom
Shanghai Changzheng Hospital

Unknown

ALK Inhibitor in Metastatic Colorectal Cancer With ALK Mutation.

Colorectal Cancer

China
Henry Friedman

Completed

Pilot Study of Bone Marrow/Stem Cells in Grade IV Malignant Glioma

Grade IV Malignant Glioma

United States
Synvista Therapeutics, Inc

Completed

The SILVER Study: Systolic Hypertension Interaction With Left Ventricular Remodeling

Hypertension | Hypertrophy, Left Ventricular
Yale University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Juvenile...

Completed

Anti-CD3 mAb Treatment of Recent Onset Type 1 Diabetes

Type 1 Diabetes Mellitus

United States
First Affiliated Hospital Xi'an Jiaotong University

Recruiting

Registry Study for Optimal Management of Liver Failure in the Chinese Population (RESOLVE-C)

Liver Failure

China
Aligos Therapeutics

Active, not recruiting

ALG-055009 in Non-cirrhotic Adults With MASH (HERALD) (HERALD)

Nonalcoholic Steatohepatitis | NASH | MASH | Metabolic Dysfunction-Associated Steatohepatitis

United States
Biogen
Alkermes, Inc.

Completed

A Study of ALKS 8700 in Adults With Relapsing Remitting Multiple Sclerosis (MS) EVOLVE-MS-1

Multiple Sclerosis

United States, Bulgaria, Poland, Belgium, Canada, Germany, Russian Federation, Serbia, Spain, Ukraine
Alume Biosciences, Inc.

Completed

A Study of ALM-488 to Highlight Nerves in Patients Undergoing Head & Neck Surgery

Head and Neck Neoplasms | Surgery | Thyroid Neoplasms | Nerve Injury | Parotid Neoplasm | Imaging

United States

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