Search clinical trials for: AMG 553

Total 3157 results

Amgen

Withdrawn

Study Evaluating the Safety, Tolerability, and Efficacy of FLT3 CAR-T AMG 553 in FLT3-positive Relapsed/Refractory AML

Relapsed/Refractory Acute Myeloid Leukemia

United States
Amgen

Terminated

Safety Study of AMG 557 in Subjects With Subacute Cutaneous Lupus Erythematosus

Cutaneous Lupus | Lupus

United States, Australia, Canada
GlaxoSmithKline

Completed

A Study in Asthmatics to Determine the Efficacy and Dose Response of Repeat Doses of GW870086X on Forced Expiratory Volume in 1 Second (FEV1)

Asthma

Germany, South Africa, Bulgaria
Amgen

Completed

A Study of AMG 557 in Adults With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United States, Canada
J2H Biotech

Completed

Phase 1 Study to Investigate Safety, Tolerability, PK/PK of J2H-1702 in Healthy Males

Non-alcoholic Steatohepatitis

Korea, Republic of
Amgen

Completed

AMG 853 Phase 2 Study in Subjects With Inadequately Controlled Asthma

Asthma
Amgen

Completed

A Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of AMG 557 in Subjects With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United States, United Kingdom
Amgen

Completed

Safety, Tolerability, and Pharcodynamics of AMG 853 in Adolescents With Asthma

Asthma
Amgen

Completed

Safety Study of AMG 557 in Subjects With Lupus Arthritis

Lupus Arthritis, Systemic Lupus Erythematosus

United States, Taiwan, Germany, Denmark, Australia, United Kingdom, Malaysia, France
Amgen

Terminated

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Clinical Effects of AMG 557 in Adults With Psoriasis

Psoriasis

United States
MedImmune LLC
Amgen

Completed

A Phase 2a, Randomized, Placebo Controlled, Study to Evaluate the Safety and Efficacy of AMG 557/MEDI5872 in Primary Sjögren's Syndrome

Primary Sjögren's Syndrome

United States, Sweden, France, United Kingdom
Helixmith Co., Ltd.

Completed

Safety Study of Gene Therapy in Treating Lower Leg Ischemia

Critical Limb Ischemia

United States
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin China Pharmaceutical Co., LTD.

Completed

Pharmacokinetic Study of KHK7580 in Healthy Adult Volunteers

Healthy Volunteer

China
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating AGG-523 in Subjects With Osteoarthritis

Osteoarthritis

United States
Multitude Therapeutics (Australia) Pty Ltd

Recruiting

AMT-253 in Patients With Selected Advanced Solid Tumours

Advanced Solid Tumor

Australia
Can-Fite BioPharma

Completed

Safety and Efficacy Study of CF101 to Treat Psoriasis

Plaque Psoriasis

Israel
GlaxoSmithKline

Completed

A Comparison of Atorvastatin and Glimepiride Fixed Dose Combination and Atorvastatin and Glimepiride Loose Combination in the Treatment of Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

Korea, Republic of, Malaysia, Philippines, Thailand, Russian Federation, Mexico
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Doses in Healthy

Osteoarthritis | Healthy Subjects

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

A Study of the Safety, Tolerability, and Pharmacokinetics of AGG-523 in Healthy Japanese Males

Healthy

Japan
Johns Hopkins University
Cultivate Biologics

Completed

The Pharmacokinetics and Pharmacodynamics of a Single Acute Dose of a Hemp-derived Oral Product With a 1:1 Ratio of CBD:CBD-A

Cannabis

United States
Multitude Therapeutics Inc.

Recruiting

AMT-253 in Patients With Advanced Solid Tumours

Advanced Solid Tumors | Malignant Melanoma

China
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating AGG-523 in Subjects With Severe Osteoarthritis Requiring Total Knee Replacement

Osteoarthritis

United States
Amgen

Recruiting

A Study Evaluating Bemarituzumab in Solid Tumors With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression (FORTITUDE-301)

Solid Tumors

Canada, Korea, Republic of, Australia, Netherlands, United States, Israel, Austria, Spain, United Kingdom, France, Belgium, Japan, Czechia, Hungary, Poland, Brazil, Argentina, Denmark, Greece, Mexico, Switzerland, Romania, Italy, Finland and more
Amgen

Completed

Single-dose, Pharmacokinetics of AMG 853 in Healthy Adult Subjects

Healthy Volunteers
Beijing Immunochina Medical Science & Technology...

Not yet recruiting

Safety and Efficacy of Chimeric Antigen Receptor T Lymphocytes for Patients With Intermediate and Advanced Tumors

Melanoma | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma

China
MingSight Pharmaceuticals, Inc
Shenzhen MingSight Relin Pharmaceutical Co., Ltd

Recruiting

A Study of MS-553 in Patients With Relapsed or Refractory B-cell Lymphoma

Chronic Lymphocytic Leukemia (CLL) | Small Lymphocytic Lymphoma (SLL) | Mantle Cell Lymphoma (MCL) | Diffuse Large B-cell Lymphoma (DLBCL) | Follicular Lymphoma (FL) | Relapsed or Refractory B-cell Lymphoma | Marginal Zone Lymphoma (MZL)

China
Yuhan Corporation

Completed

Phase 1/2a Trial of YH12852 in Healthy Subjects and Patients With Functional Constipation

Functional Constipation

Korea, Republic of
Pfizer

Completed

Multiple Oral Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PF-04878691

Hepatitis C Virus

United States
Hangzhou Grand Biologic Pharmaceutical, Inc.
Peking Union Medical College Hospital

Unknown

Study of Pharmacokinetics, Pharmacodynamics, Safety, and Immunogenicity of of HZBio1 in Healthy Subjects

Healthy Participants

China
Shenzhen MingSight Relin Pharmaceuticals Co., Ltd.

Recruiting

A Study to Investigate the Efficacy and Safety of MS-553 in CLL/SLL

Small Lymphocytic Lymphoma | Lymphocytic Leukemia

China
Shenzhen MingSight Relin Pharmaceuticals Co., Ltd.
Fountain Medical Development Co., Ltd.

Recruiting

MS-553 in Diabetic Retinopathy Patients With Central Involved Macular Edema

Diabetic Retinopathy | Diabetic Macular Edema | Macular Edema | Type 2 Diabetes With Diabetic Macular Edema | Type 1 Diabetes With Diabetic Macular Edema

China
MingSight Pharmaceuticals Pty Limited

Completed

A Multiple-Ascending Dose Study of MS-553 in Healthy Volunteers

Safety and PK in Healthy Volunteers

Australia
University of Edinburgh
NHS Lothian

Completed

Cardiovascular Effects of Apelin In Healthy Volunteers

Healthy

United Kingdom
Otsuka Pharmaceutical Co., Ltd.

Recruiting

A Dose-ranging Trial of OPC-131461 in Cardiac Edema (Congestive Heart Failure [CHF])

Cardiac Edema (CHF)

Japan
Technical University of Munich

Completed

Comparison of AMG and EMG to Avoid Residual Paralysis After General Anesthesia (CAMEM)

Anaesthesia | Respiratory Paralysis | Observation of Neuromuscular Block

Germany
University of Southampton

Not yet recruiting

Attentional Bias Modification Training for People With Chronic Musculoskeletal Pain (I-ABMT)

Chronic Pain

United Kingdom
AbbVie

Terminated

A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of ABBV-553 in Healthy Volunteers and in Subjects With Psoriasis and Efficacy of ABBV-553 in Subjects With Psoriasis

Psoriasis

United States
Newish Technology (Beijing) Co., Ltd.

Recruiting

NWRD06 DNA Plasmid for HCC After Radical Resection

Hepatocellular Carcinoma

China
Amgen

Completed

A Rheumatoid Arthritis (RA) Study Treating Signs and Symptoms of RA in People With RA & Receiving Methotrexate

Rheumatoid Arthritis
Boryung Pharmaceutical Co., Ltd

Completed

A Multi Doses Study to Compare the Pharmacokinetics of BR9003A and BR9003 in Healthy Adult Subjects

Smoking Cessation

Korea, Republic of
Mitsubishi Tanabe Pharma Corporation

Completed

A Pharmacokinetic Study of MP-214 in Patients With Schizophrenia

Schizophrenia

Japan
Five Prime Therapeutics, Inc.
Zai Lab (Shanghai) Co., Ltd.

Completed

A Study of Bemarituzumab (FPA144) Combined With Modified FOLFOX6 (mFOLFOX6) in Gastric/Gastroesophageal Junction Cancer (FIGHT)

Gastric Cancer

United States, Spain, China, Italy, Korea, Republic of, Portugal, Taiwan, Japan, Turkey, France, Hungary, Thailand, Germany, Poland, Australia, Belgium, Romania, United Kingdom
Sunovion

Completed

A Study to Evaluate a Drug (Dasotraline) on the Safety, Effectiveness and How Well the Body Tolerates it, in Adults With Moderate to Severe Binge Eating Disorder

Binge Eating Disorder

United States
Abalonex, LLC

Not yet recruiting

Safety and Efficacy of ABX-101 in Participants Aged 18 to 50 Years of Age With Moderate to Severe Traumatic Brain Injury

Traumatic Brain Injury | Cerebral Edema
Rigel Pharmaceuticals

Completed

A Safety and Efficacy Study of Inhaled R940343 in Patients With Mild to Moderate Asthma (SITAR)

Asthma

United States, Canada
Hanmi Pharmaceutical Company Limited

Completed

Duration of P-glycoprotein Inhibition After Oral Administration of HM30181AK Tablet (PGP inhibitor)

Healthy

Korea, Republic of
Pfizer

Completed

A Study To Examine Safety, Pharmacokinetics, And Pharmacodynamic Of Pf 06412562 In Subjects With Schizophrenia

Schizophrenia

United States
Amgen

Completed

Study of AMG 994 Monotherapy and AMG 994 and AMG 404 Combination Therapy in Participants With Advanced Solid Tumors

Advanced Solid Tumors

Belgium, Canada, Australia, United States, Spain, Poland, France, Germany, Japan, United Kingdom
GeneScience Pharmaceuticals Co., Ltd.
Peking University People's Hospital

Completed

A Phase 2, Randomized, Placebo-controlled, Double-blind Study of EG017 in Female Patients With Stress Urinary Incontinence

Stress Urinary Incontinence

China
Zydus Therapeutics Inc.

Completed

Saroglitazar Magnesium in the Treatment of Non-Alcoholic Steatohepatitis (EVIDENCES VI)

Non Alcoholic Steatohepatitis

United States

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