Search clinical trials for: AP 12009

Total 428 results

Merck Sharp & Dohme LLC
Ariad Pharmaceuticals

Completed

Study of Oral Ridaforolimus (AP23573, MK-8669) to Treat Patients With Refractory or Advanced Malignancies (MK-8669-016 AM4)(COMPLETED)

Cancer
Medical University of Gdansk

Completed

Optimalization of Nephroprotection Using N-Acetylcysteine

Proteinuria | Chronic Kidney Disease
VA Office of Research and Development

Terminated

PTSD Symptom Reduction by Propranolol Given After Trauma Memory Activation

Posttraumatic Stress Disorders

United States
Rambam Health Care Campus

Unknown

Dietary Intervention Program for Pre-eclampsia in Women at Risk

Pre-eclampsia
Merck Sharp & Dohme LLC
Ariad Pharmaceuticals

Completed

Phase II Study of Ridaforolimus (MK-8669) With Metastatic Bone or Soft-tissue Sarcoma Patients (MK-8669-030 AM1)

Sarcoma
Tianjin Medical University General Hospital

Not yet recruiting

Propranolol on Post Stroke Immune Status and Infection

Cardiovascular Diseases | Stroke | Cerebrovascular Disorders | Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Ischemic Stroke | Molecular Mechanisms of Pharmacological Action | Physiological Effects of Drugs | Propranolol | Immunologic Factors | Beta Blocker

China
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Brigatinib and Bevacizumab for the Treatment of ALK-Rearranged Locally Advanced, Metastatic, or Recurrent NSCLC

Metastatic Lung Non-Small Cell Carcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Stage IIIC Lung Cancer AJCC v8 | Locally Advanced Lung Non-Small... and other conditions

United States
Merck Sharp & Dohme LLC
Ariad Pharmaceuticals

Completed

Safety Study of AP23573 in Patients With Advanced, Refractory or Recurrent Malignancies (8669-013)(COMPLETED)

Lymphoma | Multiple Myeloma | Tumors

United States
University of Pittsburgh
National Institutes of Health (NIH); National Institute on Aging (NIA)

Completed

Zoledronic Acid for Osteoporosis in the Elderly (ZEST)

Osteoporosis | Bone Loss | Fragility Fractures

United States
Merck Sharp & Dohme LLC
Ariad Pharmaceuticals

Completed

AP23573 in Female Adult Patients With Recurrent or Persistent Endometrial Cancer (8669-019)(COMPLETED)

Endometrial Cancer
Bial - Portela C S.A.
Sunovion

Completed

Efficacy and Safety of Eslicarbazepine Acetate (BIA 2-093) as Adjunctive Therapy for Refractory Partial Seizures

Partial Epilepsy

United States, Argentina, Germany, France, Belgium, Canada, Italy, Poland, Greece, Brazil, Cyprus
Bial - Portela C S.A.

Completed

Eslicarbazepine Acetate (BIA 2-093) as Monotherapy in Patients With Newly Diagnosed Partial-onset Seizures

Epilepsy
People's Hospital of Guangxi

Unknown

Icotinib With Concurrent Radiotherapy vs. Chemoradiotherapy in Non-small Cell Lung Cancer

Non-small Cell Lung Cancer

China
Betta Pharmaceuticals Co., Ltd.

Unknown

Sequential and Maintenance Icotinib Plus Chemotherapy Versus Icotinib Maintenance After Chemotherapy in Advanced NSCLC

Adenocarcinoma | EGFR Positive Non-small Cell Lung Cancer

China
MacroGenics

Completed

A Study of MGD013 in Patients With Unresectable or Metastatic Neoplasms

Cervical Cancer | Hematologic Neoplasms | Ovarian Cancer | Non Small Cell Lung Cancer | Advanced Solid Tumors | Squamous Cell Carcinoma of Head and Neck | Cholangiocarcinoma | Small-cell Lung Cancer | TNBC - Triple-Negative Breast Cancer | HER2-positive Advanced Solid Tumors

Hong Kong, United States, Thailand, Australia, Spain, Bulgaria, Poland, Ukraine
Merck Sharp & Dohme LLC
Ariad Pharmaceuticals

Terminated

A Study of Ridaforolimus in Non-Small Cell Lung Cancer (NSCLC) Patients With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutations (MK-8669-021 AM1)

Non-Small Cell Lung Cancer
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Effect of MK-8669 (Ridaforolimus) on QTc Interval in Participants With Advanced Cancer (MK-8669-037)

Metastatic or Locally Advanced Cancer
Merck Sharp & Dohme LLC
Ariad Pharmaceuticals

Completed

Ridaforolimus in Treatment of Sarcoma-SUCCEED (Sarcoma Multi-Center Clinical Evaluation of the Efficacy of Ridaforolimus)(8669-011 AM6) (SUCCEED)

Metastatic Soft-Tissue Sarcomas | Metastatic Bone Sarcomas
Bial - Portela C S.A.

Completed

Efficacy and Safety of Eslicarbazepine Acetate as Therapy in Subjects With Fibromyalgia

Fibromyalgia
Blokhin's Russian Cancer Research Center

Recruiting

Neoadjuvant Combination of Doxorubicin, Cisplatin and Methotrexate in Patients Aged 24-40 Years With Primary Bone Tumors

Sarcoma | Neoplasms, Connective and Soft Tissue | Osteosarcoma | Neoplasms, Connective Tissue | Sarcoma of Bone

Russian Federation
Jorge L Poo

Completed

Prolonged Release Pirfenidone Versus Placebo in Compensated Cirrhosis. (ODISEA)

Cirrhosis, Liver | Liver Fibrosis | Chronic Liver Disease
Cadila Pharnmaceuticals
New Millennium Indian Technology Leadership Initiative (NMITLI) program of...

Completed

Effect of CPL-2009-0031 in the Treatment of Patients With Uncontrolled Type 2 Diabetes Mellitus

Uncontrolled Type 2 Diabetes Mellitus

India
Bial - Portela C S.A.

Terminated

Efficacy and Safety of Eslicarbazepine Acetate (BIA 2-093) in Acute Manic Episodes Associated With Bipolar I Disorder

BIPOLAR I DISORDER
University of Cologne

Completed

Effect of Red Wine, White Wine and Beer on Contrast-Medium Induced Acute Kidney Injury (RenPro-II-WINE)

Chronic Renal Failure/ Kidney Disease | Contrast-medium Induced Acute Kidney Injury

Germany
Assaf-Harofeh Medical Center

Unknown

Effect of N-Acetylcysteine on Peritoneal Membrane Function in Chronic Peritoneal Dialysis Patients

Peritoneal Dialysis | ESRD

Israel
Beijing Bio-Fortune Ltd.

Completed

Recombinant Human Serum Albumin/Interferon alpha2a Fusion Protein Phase I Study in Chinese Healthy Volunteers

Healthy Volunteers

China
N.N. Petrov National Medical Research Center of...
The Foundation for Cancer Research Support (RakFond)

Recruiting

Multicentral Preventive Antibiotics With Cystectomy Within Enhanced Recovery After Surgery (MACS)

Bladder Cancer

Russian Federation
Olivia Newton-John Cancer Research Institute
Austin Health; Roche Products Pty Limited; Ballarat Health Services

Active, not recruiting

Frontline Treatment of Follicular Lymphoma With AtezolizUmab and Obinutuzumab With and Without RadiOtherapy (FLUORO)

Follicular Lymphoma

Australia
Merck Sharp & Dohme LLC
Ariad Pharmaceuticals

Terminated

Extension Trial of Deforolimus (Ridaforolimus, MK-8669) in Participants With Advanced Cancer (MK-8669-038)

Advanced Cancers
Assaf-Harofeh Medical Center

Unknown

Effect of NAC on Sleep Apnea

Sleep Apnea | ESRD

Israel
CicloMed LLC
Cmed Clinical Services

Completed

Safety, Dose Tolerance, Pharmacokinetics, and Pharmacodynamics Study of CPX-POM in Patients With Advanced Solid Tumors

Advanced Solid Tumors

United States
Merck Sharp & Dohme LLC

Completed

Oral Deforolimus With Trastuzumab for Patients With HER2-positive Trastuzumab-Refractory Metastatic Breast Cancer (8669-009)

Breast Cancer | Breast Neoplasms
Fondazione Melanoma Onlus
Clinical Research Technology S.r.l.

Active, not recruiting

Combination or Sequence of Vemurafenib, Cobimetinib, and Atezolizumab in High-risk, Resectable Melanoma (NEO-TIM)

Melanoma

Italy
Children's Hospital Los Angeles

Completed

Change in Oxygen Consumption Following Inhalation Beta Agonists in Healthy Adults

Oxygen Consumption
Pfizer

Completed

A Study To Assess The Effect Of Linezolid On QTc Interval

Bacterial Infections

Singapore
St. Louis University

Completed

SSRIs vs. TCAs for Depression in ALS Patients

Depression | Amyotrophic Lateral Sclerosis

United States
ClinAssess
Sanofi; Merck Sharp & Dohme LLC

Completed

Docetaxel, Cisplatin (TP) + Radiation +/- Cetuximab in Larynx Carcinoma (CA) (DeLOS II)

Squamous Cell Carcinoma of the Hypopharynx | Larynx Carcinoma

Germany, Austria
Bausch Health Americas, Inc.

Completed

Daily-Dose Consensus Interferon and Ribavirin: Efficacy of Combined Therapy

Chronic Hepatitis C
Janssen Pharmaceutica N.V., Belgium

Completed

A Study of Ponesimod in Healthy Adult Participants Receiving Propranolol at Steady State

Healthy

Belgium
Instituto Oncológico Dr Rosell
Roche Pharma AG; Fundacion Clinic per a la Recerca Biomédica

Active, not recruiting

Combination of Atezolizumab With Dendritic Cell Vaccine in Patients With Lung Cancer (VENEZO-LUNG)

Extensive-stage Small Cell Lung Cancer

Spain
AstraZeneca

Completed

A Study to Assess the Bioavailability and to Compare the Pharmacokinetics of AZD7594 Inhaled Via Monodose Inhaler and Multiple-dose Dry Powder Inhalers (DPI) or Pressurized Metered-dose Inhaler (pMDI) in Healthy Male Subjects

Asthma | Chronic Obstructive Pulmonary Disease (COPD)

United States
Bausch Health Americas, Inc.

Completed

Daily-Dose Consensus Interferon and Ribavirin: Efficacy of Combined Therapy

Chronic Hepatitis C
Seoul National University Hospital

Completed

Effect of SLCO2B1 Genotype and Apple Juice on Pharmacokinetics of Atenolol After Oral Administration in Healthy Male Korean

Healthy

Korea, Republic of
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Cardiac Safety of a Single Dose of AL-335 Administered on a Background of Simeprevir and Odalasvir and of Repeated Doses of Odalasvir Administered Alone in Healthy Participants

Healthy

United States
German Cancer Research Center
Charite University, Berlin, Germany; Roche Pharma AG; Johannes Gutenberg University... and other collaborators

Recruiting

A MultIceNTER Phase I Peptide VaCcine Trial for the Treatment of H3-Mutated Gliomas (INTERCEPT-H3)

Newly Diagnosed H3-mutated Glioma

Germany
International Medical University

Completed

Vitamin D Supplementation and PTH Response Among Malaysian Adults

Healthy

Malaysia
University Hospital Heidelberg
Dietmar Hopp Stiftung

Recruiting

Predicting Response to Neoadjuvant ATEZOLIZUMAB Plus Carboplatin/Nab Paclitaxel in Resectable Non-squamous NSCLC (iReP)

NSCLC Stage IIIB | NSCLC Stage II | NSCLC, Stage IIIA

Germany
Darell Bigner
National Cancer Institute (NCI); Genentech, Inc.; Istari Oncology, Inc.

Active, not recruiting

D2C7-IT With Atezolizumab for Recurrent Gliomas

Malignant Glioma

United States
I.M. Sechenov First Moscow State Medical University
Prokhorov General Physics Institute of the Russian Academy of Sciences (GPI...

Completed

COVID-19 Treatment Using Methylene Blue and Photodynamic Therapy

SARS-CoV-2

Russian Federation
Christoph Gasche
Prof. Dr. Gabriela Möslein, Germany; Prof. Dr. Hans Vasen, The Netherlands; Prof... and other collaborators

Terminated

Mesalamine for Colorectal Cancer Prevention Program in Lynch Syndrome (MesaCAPP)

Colorectal Cancer

Netherlands, Austria, Germany, Israel, Poland, Sweden

Search clinical trials for: AP 12009

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