Search clinical trials for: APTO-253

Total 3251 results

Bayer

Active, not recruiting

A Study to Assess How Radium-223 Distributes in the Body of Patients With Prostate Cancer Which Spread to the Bones

Bone Metastatic Castration-resistant Prostate Cancer

France, Lithuania, Israel, Italy, United Kingdom, Austria
Hoffmann-La Roche

Completed

Safety and Tolerability of Atezolizumab (ATZ) in Combination With Radium-223 Dichloride (R-223-D) in Metastatic Castrate-Resistant Prostate Cancer (CRPC) Progressed Following Treatment With an Androgen Pathway Inhibitor

Castrate-Resistant Prostate Cancer

United States
University Health Network, Toronto
GlaxoSmithKline

Not yet recruiting

Belimumab in Autoimmune Hepatitis (BELief)

Autoimmune Hepatitis
Amgen

Completed

Efficacy and Safety Study of ABP 501 Compared to Adalimumab in Subjects With Moderate to Severe Rheumatoid Arthritis

Arthritis, Rheumatoid

United States, Canada, Germany, United Kingdom
Genentech, Inc.

Completed

A Study to Evaluate Pain, Tolerability, Safety, and Usability of a Single Self-administered Etrolizumab by Auto-injector in Healthy Participants

Healthy Volunteer

United States
Philips Respironics

Completed

Sleep Disordered Breathing and Chronic Pain

Sleep Apnea Syndromes

United States
M.D. Anderson Cancer Center
Bayer

Completed

Trial of Ra-223 Dichloride in Combination With Hormonal Therapy and Denosumab in the Treatment of Patients With Hormone-Positive Bone-Dominant Metastatic Breast Cancer

Breast Cancer

United States
Bayer

Completed

Descriptive Analysis of Clinical Outcomes in Patients With Prostate Gland Cancer, Which Spreads to Other Parts of the Body, Who Were Treated First With Novel Anti-hormone Therapy Followed by a Second Line Treatment With Novel Anti-Hormone Therapy or RadIum-223 (Xofigo). (PHENIX)

Metastatic Castration-resistant Prostate Cancer (mCRPC)

United States
Bayer

Completed

PRECISE, a Study to Gather More Information About Bone Fractures and Survival in Castration-resistant PRostate Cancer (CRPC) patiEnts Treated With Radium-223 in Routine Clinical practIce in SwedEn (PRECISE)

Metastatic Castration-Resistant Prostate Cancer

Sweden
Carolina Research Professionals, LLC
Astellas Pharma Inc

Completed

Open Label Phase Two Study of Enzalutamide With Concurrent Administration of Radium Ra 223 Dichloride in Castration-Resistant (Hormone-Refractory) Prostate Cancer Subjects With Symptomatic Bone Metastasis

Prostate Carcinoma Metastatic to the Bone

United States
Bayer

Withdrawn

Outcomes of mCRPC Patients Treated With Ra-223 Concomitant With Abiraterone or Enzalutamide- A Chart Review Study

Prostatic Neoplasms, Castration-Resistant
Tehran University of Medical Sciences

Completed

Treatment of Non Promyelocytic Acute Myeloid Leukaemia on Elderly Patients by Low Dose Cytosar Plus Arsenic Trioxide

Leukemia, Myeloid, Acute

Iran, Islamic Republic of
Bayer

Completed

BAY88-8223, Alpharadin, Breast Cancer Patients With Bone Dominant Disease

Breast Cancer | Bone Metastases

Belgium, United Kingdom, Norway
University Health Network, Toronto
Canadian Institutes of Health Research (CIHR); University of Toronto

Completed

Can Valacyclovir Attenuate Inflammation in Antiretroviral-Treated HIV-Infected Individuals With Herpes Simplex Virus Type 2? (VALIANT Pilot)

Herpes Simplex | Human Immunodeficiency Virus

Canada
Peter MacCallum Cancer Centre, Australia

Recruiting

Combination of Radium-223 and Lutetium-177 PSMA-I&T in Men With Metastatic Castration-Resistant Prostate Cancer (AlphaBet)

Prostate Cancer | Metastatic Castration-resistant Prostate Cancer | mCRPC

Australia
North Dakota State University

Terminated

microRNA Testing for Identification of Personalized Weight Management

Weight Loss | Overweight and Obesity

United States
Zeria Pharmaceutical

Completed

Pharmacokinetics, Pharmacodynamics and Safety Study of Z-213 to Iron Deficiency Anemia

Iron Deficiency Anemia

Japan
Wyeth is now a wholly owned subsidiary of Pfizer
Pfizer

Completed

Study Evaluating Multiple Doses Of GSI-953 Within The Elderly Population

Healthy

United States
Sanofi

Completed

Association of Type 1 Diabetes Mellitus in Offsprings With Positive Parental History of Diabetes (SHINE)

Type 1 Diabetes

Pakistan
Memorial Sloan Kettering Cancer Center
BioMed Valley Discoveries, Inc

Recruiting

Ulixertinib in People With Histiocytic Neoplasms

Histiocytic Neoplasms

United States
Zhongshan Ophthalmic Center, Sun Yat-sen University

Recruiting

Pars-plana Vitrectomy vs Panretinal Photocoagulation for Severe NPDR

Non Proliferative Diabetic Retinopathy

China
Janssen Research & Development, LLC

Completed

A Study of JNJ-77242113 for the Treatment of Moderate-to-Severe Plaque Psoriasis (SUMMIT)

Plaque Psoriasis

United States, Canada, Germany, France, Spain, Poland
GenMont Biotech Incorporation

Completed

Effects of Genmont Probiotic on Improve the Level of Blood Glucose and Other Diabetic Associate Parameter in Type 2 Diabetes Patients

Type 2 Diabetes

Taiwan
University of Missouri-Columbia

Recruiting

Dietary Fiber Effects on the Microbiome and Satiety (FEMS)

Dietary Fiber

United States
The S.N. Fyodorov Eye Microsurgery State Institution
Alcon Research

Completed

Evaluation of Axial Stability of Two Models of Intraocular Lenses in Patients With an Eye Length More Than 26 mm

Corneal Astigmatism | Cataract Senile | Myopia, High-Grade

Russian Federation
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Gene Therapy in Treating Patients With Non-small Cell Lung Cancer That Cannot Be Surgically Removed

Lung Cancer

United States
Vaccinex Inc.
PRA Health Sciences

Completed

Evaluation of Safety, Tolerability, and PK of VX15/2503 In Patients With MS

Multiple Sclerosis

United States
Tioga Pharmaceuticals

Completed

A Metabolite Identification, Mass Balance, and PK Study of [14C]-Asimadoline to Healthy Adult Male Volunteers

Healthy

United States
National Cancer Institute (NCI)

Completed

Gene Therapy in Treating Patients With Recurrent or Progressive Brain Tumors

Brain and Central Nervous System Tumors
Fisher and Paykel Healthcare

Completed

Validation of HC250 and HC240 Series.

Obstructive Sleep Apnea (OSA)

New Zealand
Eli Lilly and Company

Terminated

A Study of Tabalumab (LY2127399) Using Two Different Injection Methods in Participants With Lupus

Lupus Erythematosus, Systemic

Korea, Republic of, Puerto Rico, United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

P53MVA and Pembrolizumab in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Recurrent Platinum-Resistant Ovarian Carcinoma | Recurrent Platinum-Resistant Fallopian Tube Carcinoma | Recurrent Platinum-Resistant Primary Peritoneal Carcinoma

United States
Dana-Farber Cancer Institute
Bayer

Completed

Exploratory Study of Radium-223 and VEGF-Targeted Therapy in Patients With Metastatic Renal Cell Carcinoma and Bone Mets

Metastatic Renal Cell Carcinoma

United States
Aalborg University Hospital

Completed

Effects of Marine n-3 Fatty Acids on Heart Rate Variability and Arrhythmias in Patients Receiving Chronic Dialysis

Kidney Failure Chronic | Arrhythmias Cardiac

Denmark
Clinical Research Center Kiel GmbH
Nofima

Completed

Glycemic Response to Two Doses of Low Sugar Apple Juice (HB-RCT2-2015)

Prediabetes

Germany
Centre for Addiction and Mental Health
The Physicians' Services Incorporated Foundation

Recruiting

Minocycline as Adjunctive Treatment for Treatment Resistant Depression (MINDEP2)

Treatment Resistant Depression

Canada
Massachusetts General Hospital
Dana-Farber Cancer Institute

Completed

Tandem Auto-Allo Transplant for Lymphoma

Hodgkin's Lymphoma | Chronic Lymphocytic Leukemia | Lymphoma, Low-Grade | Diffuse, Large B-Cell, Lymphoma | T-Cell Lymphoma | Mantle-Cell Lymphoma | Lymphoma, Small Lymphocytic

United States
Vertex Pharmaceuticals Incorporated
Cystic Fibrosis Foundation

Completed

Safety Study of Ivacaftor in Subjects With Cystic Fibrosis

Cystic Fibrosis

United States, Canada, Germany
Double Bond Pharmaceutical AB

Not yet recruiting

A Dose Escalation Study to Estimate MTD, DLTs and Pharmacokinetics After a Single Intracranial Dose of SI-053 as an add-on to the Current Standard of Care, in Adult Patients With Newly Diagnosed GBM (TARGLIO)

Newly Diagnosed Glioblastoma
Duke University
National Heart, Lung, and Blood Institute (NHLBI); American Heart Association

Completed

Ketone Pharmacokinetic Study in HFrEF

Heart Failure With Reduced Ejection Fraction

United States
October 6 University

Completed

A Comparative Study Between Three Different Plating Techniques in Management of Mandibular Parasymphyseal Fractures.

Mandibular Fractures

Egypt
Allievex Corporation

Active, not recruiting

A Treatment Extension Study of Mucopolysaccharidosis Type IIIB

Mucopolysaccharidosis Type IIIB | MPS III B

Germany, United States, Turkey, United Kingdom, Colombia, Spain, Taiwan
Sidney Kimmel Comprehensive Cancer Center at Johns...
Bayer; Dendreon

Completed

Study of Sipuleucel-T W/ or W/O Radium-223 in Men With Asymptomatic or Minimally Symptomatic Bone-MCRPC

Prostate Cancer

United States
Celgene

Completed

A Phase 1 Open-Label Study to Evaluate the Metabolism and Excretion of CC-223 and the Effect of Food on the Pharmacokinetics of CC-223 in Healthy Male Adult Subjects (AME/FE)

Safety and Pharmacokinetics in Healthy Volunteer Subjects

United States
Tatyasaheb Kore Dental College

Completed

Effect Of A Locally Delivered Probiotic Sacchraomyces Boulardii In The Management Of Chronic Periodontitis

Chronic Periodontitis

India
GlaxoSmithKline

Completed

Dose Ranging Efficacy And Safety With Mepolizumab in Severe Asthma (DREAM)

Asthma

United States, Argentina, Australia, Germany, Poland, Romania, Russian Federation, Ukraine, Canada, Chile, France, Korea, Republic of, United Kingdom
National Cancer Institute (NCI)

Terminated

Gene Therapy in Treating Patients With Cancer of The Liver

Liver Cancer

United States
Shenzhen SiBiono GeneTech Co.,Ltd

Unknown

Surgery Combined With rAd-p53 Gene in Treatment Advanced Non-small-cell Carcinoma (rAd-p53)

Non-small Cell Lung Cancer

China
Basque Health Service

Completed

Comparison of Two Telemonitoring Auto-titrating Modalities in OSA Patients

Sleep Apnea Syndromes | Sleep Apnea, Obstructive | Apnea | Sleep Disorders, Intrinsic | Sleep Wake Disorders | Sleep Disordered Breathing | Respiratory Tract Disease | Respiration; Sleep Disorder

Spain
Sanofi

Completed

GLP-1 Receptor Agonist Lixisenatide (Morning or Evening) in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Metformin (GETGOAL-M)

Diabetes Mellitus, Type 2

United States, Canada, Romania, Russian Federation, Ukraine, Germany, Spain, Philippines, Czech Republic, Mexico, Croatia, Chile, Morocco, South Africa, Australia, Venezuela

Search clinical trials for: APTO-253

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