Search clinical trials for: ARRY-142886, MEK inhibitor; oral
Total 3588 results
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Array Biopharma, now a wholly owned subsidiary...Completed
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National Cancer Institute (NCI)Completed
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National Cancer Institute (NCI)TerminatedRecurrent Adult Diffuse Large Cell LymphomaUnited States
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National Cancer Institute (NCI)CompletedRefractory Plasma Cell Myeloma | Recurrent Plasma Cell MyelomaUnited States
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National Cancer Institute (NCI)CompletedStage IV Skin Melanoma | Recurrent Melanoma | Stage III Skin MelanomaUnited States
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National Cancer Institute (NCI)NRG OncologyCompletedRecurrent Uterine Corpus Carcinoma | Endometrial Clear Cell Adenocarcinoma | Endometrial Adenocarcinoma | Endometrial Adenosquamous CarcinomaUnited States
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Array Biopharma, now a wholly owned subsidiary...CompletedRheumatoid ArthritisBrazil, Argentina, United States, Poland, Hungary, Peru, Romania
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Array Biopharma, now a wholly owned subsidiary...Completed
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National Cancer Institute (NCI)Active, not recruitingLow Grade Glioma | Recurrent Visual Pathway Glioma | Refractory Visual Pathway Glioma | Recurrent Childhood Pilocytic Astrocytoma | Recurrent Neurofibromatosis Type 1 | Refractory Neurofibromatosis Type 1United States
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AstraZenecaActive, not recruitingCancer | TumorUnited States, Netherlands, United Kingdom
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Great Ormond Street Hospital for Children NHS Foundation...AstraZenecaCompletedNeurofibromatosis Type 1 | Optic Nerve Glioma | Plexiform NeurofibromaUnited Kingdom
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National Cancer Institute (NCI)CompletedRecurrent Thyroid Gland Carcinoma | Stage I Thyroid Gland Papillary Carcinoma | Stage II Thyroid Gland Papillary Carcinoma | Stage III Thyroid Gland Papillary Carcinoma | Stage IV Thyroid Gland Papillary CarcinomaUnited States, Canada
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National Cancer Institute (NCI)CompletedMyelodysplastic Syndromes | Recurrent Adult Acute Myeloid Leukemia | Secondary Acute Myeloid Leukemia | Adult Acute Promyelocytic Leukemia (M3) | Adult Acute Myeloid Leukemia With t(15;17)(q22;q12) | Myelodysplastic/Myeloproliferative NeoplasmsUnited States
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AstraZenecaCompletedHealthy Volunteers Pharmacokinetic StudyUnited Kingdom
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National Cancer Institute (NCI)Active, not recruitingAdvanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Recurrent Neuroblastoma | Refractory Neuroblastoma | Refractory Non-Hodgkin Lymphoma | Refractory Primary Central Nervous System Neoplasm | Ann Arbor Stage III Childhood Non-Hodgkin Lymphoma and other conditionsUnited States, Puerto Rico
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Array Biopharma, now a wholly owned subsidiary...CompletedMetastatic Colorectal Cancer | Advanced Solid Tumors | Advanced or Metastatic Biliary CancerUnited States
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National Cancer Institute (NCI)NRG OncologyCompletedPrimary Peritoneal Carcinoma | Low Grade Ovarian Serous Adenocarcinoma | Borderline Ovarian Serous Tumor | Micropapillary Serous Carcinoma | Primary Peritoneal Low Grade Serous Adenocarcinoma | Recurrent Borderline Ovarian Surface Epithelial-Stromal TumorUnited States
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National Cancer Institute (NCI)CompletedRecurrent Extrahepatic Bile Duct Cancer | Unresectable Extrahepatic Bile Duct Cancer | Liver and Intrahepatic Biliary Tract CancerUnited States
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Jonsson Comprehensive Cancer CenterNational Cancer Institute (NCI)WithdrawnRecurrent Melanoma | Stage IV MelanomaUnited States
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Array Biopharma, now a wholly owned subsidiary...Completed
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National Cancer Institute (NCI)TerminatedRecurrent Melanoma | Stage IV Melanoma | Stage IIIA Melanoma | Stage IIIB Melanoma | Stage IIIC MelanomaUnited States
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PfizerTerminatedAnkylosing SpondylitisUnited States, Canada
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Array Biopharma, now a wholly owned subsidiary...Completed
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PfizerCompletedLMNA-Related Dilated CardiomyopathyUnited States
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PfizerCompletedLMNA-Related Dilated CardiomyopathyUnited States
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National Cancer Institute (NCI)CompletedAdvanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Adult Primary Hepatocellular CarcinomaUnited States
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Array Biopharma, now a wholly owned subsidiary...CompletedMyelodysplastic SyndromesUnited States
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Array Biopharma, now a wholly owned subsidiary...Completed
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Array Biopharma, now a wholly owned subsidiary...Completed
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Array Biopharma, now a wholly owned subsidiary...CompletedMyelodysplastic SyndromesUnited States
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National Cancer Institute (NCI)CompletedAdult Solid NeoplasmUnited States
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PfizerCompleted
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Array Biopharma, now a wholly owned subsidiary...Completed
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Array BioPharmaCompleted
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AstraZenecaCompleted
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Array Biopharma, now a wholly owned subsidiary...CompletedMetastatic CancerUnited States
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Seagen Inc.Array BioPharmaCompleted
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AstraZenecaCompletedMelanomaUnited States, Australia, Brazil, United Kingdom, Argentina, Austria, Canada, Denmark, France, Switzerland
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OHSU Knight Cancer InstituteAstraZeneca; Oregon Health and Science UniversityCompletedStage IV Non-Small Cell Lung Cancer AJCC v7 | Stage IIIB Non-Small Cell Lung Cancer AJCC v7United States
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AstraZenecaCompletedNon-small Cell Lung CancerUnited States, Bulgaria, Romania
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National Cancer Institute (NCI)Active, not recruitingMetastatic Melanoma | Stage IV Cutaneous Melanoma AJCC v6 and v7 | Refractory Malignant Solid Neoplasm | Unresectable Malignant Solid NeoplasmUnited States
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National Cancer Institute (NCI)CompletedAdenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic CancerUnited States
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AstraZenecaCompletedPancreatic CancerUnited States, Bulgaria, Hungary, Romania, Australia
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National Cancer Institute (NCI)National Comprehensive Cancer NetworkCompletedRecurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue SarcomaUnited States
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National Cancer Institute (NCI)Active, not recruitingStage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Recurrent Colorectal Carcinoma | Stage IIIA Colorectal Cancer AJCC v7 | Stage IIIB Colorectal Cancer AJCC v7 | Stage IIIC Colorectal Cancer AJCC v7 | Solid NeoplasmUnited States, Canada
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Atriva Therapeutics GmbHSGS Life Sciences, a division of SGS Belgium NVCompleted
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University of British ColumbiaMerck Sharp & Dohme LLCTerminatedIslet TransplantationCanada
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Academic and Community Cancer Research UnitedNational Cancer Institute (NCI)Active, not recruitingRecurrent Thyroid Gland Carcinoma | Poorly Differentiated Thyroid Gland Carcinoma | Stage IV Thyroid Gland Follicular Carcinoma AJCC v7 | Stage IV Thyroid Gland Papillary Carcinoma AJCC v7 | Stage IVA Thyroid Gland Follicular Carcinoma AJCC v7 | Stage IVA Thyroid Gland Papillary Carcinoma AJCC... and other conditionsUnited States
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H. Lee Moffitt Cancer Center and Research InstituteArray BioPharmaCompletedNon-Small Cell Lung Cancer | Lung CancerUnited States