Search clinical trials for: AZD 1222

Total 272470 results

Second Xiangya Hospital of Central South University

Completed

Effects of SHR-1222 on Vascular Inflammatory Factors in Patients With Low Bone Mass

Osteoporosis, Osteopenia

China
Jiangsu HengRui Medicine Co., Ltd.

Completed

The PK/PD Study of A Single Subcutaneous Injection of SHR-1222 in Healthy Subjects

Osteoporosis

China
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Multiple Dose Study to Evaluate the Effect of SHR-1222 Injection in Postmenopausal Osteoporosis Patients

Osteoporosis

China
Ascentage Pharma Group Inc.
Suzhou Yasheng Pharmaceutical Co., Ltd.

Terminated

APG-1252 in Patients With SCLC or Advanced Solid Tumors

Small Cell Lung Cancer and Other Solid Tumors

China
Ascentage Pharma Group Inc.

Completed

A Study of APG-1252 in Patients With SCLC or Other Solid Tumors

Small Cell Lung Cancer | Solid Tumor

United States
AbbVie

Completed

A Phase 2 Study of ABBV-3067 Alone and in Combination With ABBV-2222

Cystic Fibrosis

United States, Belgium, Canada, Czechia, France, Hungary, Netherlands, New Zealand, Poland, Slovakia, United Kingdom, Serbia
TG Therapeutics, Inc.
SCRI Development Innovations, LLC

Completed

Evaluate the Safety and Efficacy of TGR 1202 in Patients With Relapsed or Refractory Hematologic Malignancies

Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | Chronic Lymphocytic Leukemia | Peripheral T-Cell Lymphoma

United States
SolAeroMed Inc.

Recruiting

Safety, Tolerability and Efficacy of S-1226 in Cystic Fibrosis and Non CF Bronchiectasis

Bronchiectasis | Cystic Fibrosis

Canada
Affinium Pharmaceuticals, Ltd

Completed

A Study of Safety, Tolerability, and Efficacy of AFN-12520000 in the Treatment of Acute Bacterial Skin and Skin Structure Infections Due to Staphylococci

Cellulitis | Wound Infection | Skin and Subcutaneous Tissue Bacterial Infections | Cutaneous Abscess | Burn Infection

United States, Canada
Jiangsu Yahong Meditech Co., Ltd aka Asieris

Not yet recruiting

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of APL-1501 Extended Release (ER) Capsules Compared to APL-1202 Immediate Release (IR) Tablets in Healthy Volunteers

Bladder Cancer

Australia
H. Lee Moffitt Cancer Center and Research Institute
TG Therapeutics, Inc.

Terminated

TGR-1202 (Umbralisib) in Treatment Naïve Patients With Chronic Lymphocytic Leukemia (CLL)

Chronic Lymphocytic Leukemia

United States
Dong-A ST Co., Ltd.

Completed

PK//PD/Tolerability Study of DA-1229(Evogliptin) in Renal Impaired Patients

Renal Impairment

Korea, Republic of
Dong-A Pharmaceutical Co., Ltd.

Unknown

A Study to Characterize the Pharmacokinetics/Pharmacodynamics and Effect of Food of DA-1229 in Healthy Male Subjects

Diabetes Mellitis Type 2

Korea, Republic of
Merck Sharp & Dohme LLC

Recruiting

Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

Heart Failure | Left Ventricular Systolic Dysfunction

Korea, Republic of, United States, France, Finland, Portugal, Sweden, Denmark, Spain, Turkey, Hungary, Netherlands, Ireland, Malaysia, Colombia, Germany, Singapore, Thailand, Italy, New Zealand, Belgium, Brazil, Canada, United Kingdom, South Africa
SolAeroMed Inc.

Not yet recruiting

Safety, Tolerability and Efficacy of S-1226 in Post-COVID-19 Subjects With Persistent Respiratory Symptoms.

Post Acute COVID-19 Syndrome | Long COVID | COVID-19 Respiratory Infection
Technophage, SA
VectorB2B

Not yet recruiting

Phase 1/2a to Assess the Safety and Tolerability of TP-122A for the Treatment of Ventilator-Associated Pneumonia (RECOVER)

Pneumonia, Ventilator-Associated

France
DualityBio Inc.

Not yet recruiting

A Study of DB-1202 Monotherapy in Advanced Solid Tumors

Advanced Solid Tumor

China
Dong-A ST Co., Ltd.

Completed

Clinical Study to Evaluate Efficacy and Safety of DA-1229 in Patients With CAVD (DIP-CAVD)

Calcific Aortic Valve Disease

Korea, Republic of
DongGuk University

Unknown

Effect of Evogliptin on Bone Metabolism in Human

Diabetes Mellitus, Type 2 | Osteoporosis

Korea, Republic of
TG Therapeutics, Inc.

Terminated

Extension Trial of Ublituximab and TGR-1202 in Combination or as Single Agents in Subjects Currently Receiving Treatment on Ublituximab and/or TGR-1202 Trials

Chronic Lymphocytic Leukemia | Non Hodgkin Lymphoma

United States
Asieris Pharmaceutical Technologies Co., Ltd.

Completed

Study of APL-1202 in Non-Muscle Invasive Bladder Cancer Patients Who Are Resistant to One Induction Course of BCG Treatment (NMIBC)

Non-Muscle Invasive Bladder Cancer (NMIBC)

United States
Cerecin

Completed

Tricaprilin in Mild to Moderate Alzheimer's Disease

Alzheimer's Disease

United States
Cerecin

Completed

Tricaprilin In Age-Associated Memory Impairment

Age-Associated Memory Impairment

United States
Ascentage Pharma Group Inc.

Recruiting

A Study of Pelcitoclax (APG-1252) in Patients With Neuroendocrine Tumors

Neuroendocrine Tumors

China
TG Therapeutics, Inc.

Completed

Study to Assess the Efficacy and Safety of Umbralisib in Participants With Non-Follicular Indolent Non-Hodgkin's Lymphoma

Waldenstrom Macroglobulinemia | Marginal Zone Lymphoma | Non Follicular Indolent Non-Hodgkin Lymphoma

United States
Parasail, LLC

Available

Intravenous VAL-1221 Lafora Expanded Access Protocol (LEAP)

Lafora Disease
Dong-A ST Co., Ltd.

Unknown

Microtracer Study to Establish Absolute Bioavailability and the Absorption, Metabolism, Excretion of DA-1229

Healthy

United Kingdom
Celgene

Completed

A Study of CC-122 to Assess the Safety and Tolerability in Japanese Patients With Advanced Solid Tumors and Non-Hodgkin's Lymphoma (NHL)

Lymphoma, Non-Hodgkin

Japan
Celgene

Completed

Radiolabeled Study of CC-122 in Healthy Subjects

Healthy Volunteers

United States
Celgene

Completed

A Study to Assess the Pharmacokinetics of CC-122 in Subjects With Mild, Moderate, and Severe Renal Impairment

Renal Insufficiency

United States
Metastatix, Inc.

Suspended

MSX-122 Administered Orally in Patients With Refractory Metastatic or Locally Advanced Solid Tumors

Solid Tumors

United States
Merck Sharp & Dohme LLC

Not yet recruiting

Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-043)

Systolic Dysfunction
Merck Sharp & Dohme LLC
Bayer; Duke Clinical Research Institute; Canadian VIGOUR Centre

Completed

A Study of Vericiguat in Participants With Heart Failure With Reduced Ejection Fraction (HFrEF) (MK-1242-001) (VICTORIA)

Heart Failure | Chronic Heart Failure With Reduced Ejection Fraction
Merck Sharp & Dohme LLC

Completed

A Study to Determine the Optimal Dose of Tildrakizumab (SCH 900222/MK-3222) for the Treatment of Moderate-to-severe Chronic Plaque Psoriasis (P05495) (MK-3222-003)

Psoriasis
Syneos Health
Asieris Pharmaceuticals (AUS) Pty Ltd.

Not yet recruiting

A Study of APL-1501 Extended Release Capsules Compared to APL-1202 Immediate Release Tablets in Healthy Volunteers

Healthy Volunteers
Ascentage Pharma Group Inc.

Recruiting

APG-1252 Monotherapy or in Combination With Other Therapeutic Agent in Subjects With Relapsed or Refractory Non-Hodgkin Lymphoma

NHL, Adult

China
Ascentage Pharma Group Inc.

Withdrawn

A Study of APG-1252 in Patients With Myelofibrosis Who Progressed After Initial Therapy

Myelofibrosis

United States
Santen Inc.

Completed

A Phase I/II Safety, Tolerability, Immunogenicity, and Bioactivity Study of DE-122 Injectable Solution for Refractory Exudative Age-related Macular Degeneration (PAVE)

Age-Related Macular Degeneration

United States
TaiwanJ Pharmaceuticals Co., Ltd

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of JKB-122 in Patients With NASH and Fibrosis

Nonalcoholic Steatohepatitis (NASH) With Fibrosis
Dong-A Pharmaceutical Co., Ltd.

Completed

Pharmacokinetic/Pharmacodynamic Drug-drug Interaction of DA-1229 and Metformin After Oral Administration in Healthy Male Subjects

Type 2 Diabetes Mellitus

Korea, Republic of
Bausch Health Americas, Inc.

Completed

Safety and Efficacy of IDP-122 in the Treatment of Participants With Plaque Psoriasis

Plaque Psoriasis

United States
Cerecin
Celerion

Completed

Evaluation of PK of AC-1204 Mixed in Water, AC-1202 Mixed in Water, and AC-1202 Mixed in Ensure® on Ketone Body Production

Healthy

United States
Botswana Harvard AIDS Institute Partnership
AstraZeneca; Botswana Ministry of Health

Completed

Incidence of COVID-19 Following Vaccination in Botswana Against SARS CoV 2

COVID-19

Botswana
Bausch Health Americas, Inc.

Recruiting

A Safety and Pharmacokinetics Study of IDP-122 Lotion in Pediatric Participants With Plaque Psoriasis

Psoriasis

United States, Panama
Therapeutics, Inc.

Completed

A Study to Determine the Efficacy and Safety of 122-0551 in Subjects With Plaque Psoriasis

Psoriasis | Plaque Psoriasis

United States
AbbVie

Completed

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Multiple Subcutaneous Injections of ABT-122 in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

United States
Dong-A ST Co., Ltd.

Completed

Pharmacokinetics and Safety of Evogliptin in Subjects With Hepatic Dysfunction

Liver Dysfunction

Korea, Republic of
Columbia University
TG Therapeutics, Inc.

Terminated

TGR1202 in Relapsed and Refractory Follicular Lymphoma

Follicular Lymphoma

United States
Valerion Therapeutics, LLC

Terminated

VAL-1221 Delivered Intravenously in Ambulatory and Ventilator-free Participants With Late-Onset Pompe Disease

Pompe Disease

United States, United Kingdom
Mersana Therapeutics

Completed

Study of Antibody Drug Conjugate in Patients With Advanced Breast Cancer Expressing HER2

Advanced Breast Cancer | Advanced Gastric Cancer | Advanced Nonsmall Cell Lung Cancer

United States

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