Search clinical trials for: Abiraterone acetate plus degarelix

Total 324 results

Memorial Sloan Kettering Cancer Center
University of California, Los Angeles; Ferring Pharmaceuticals; Wayne State University and other collaborators

Completed

3-arm Study of Abiraterone Acetate Alone, Abiraterone Acetate Plus Degarelix, a GnRH Antagonist, and Degarelix Alone for Patients With Prostate Cancer With a Rising PSA or a Rising PSA and Nodal Disease Following Definitive Radical Prostatectomy

Prostate Cancer

United States
Ferring Pharmaceuticals

Completed

A Study of Degarelix in Taiwanese Patients With Prostate Cancer

Prostate Cancer

Taiwan
Ferring Pharmaceuticals

Completed

An Extension Study Evaluating the Long-Term Safety and Tolerability of Degarelix One-Month Depots in Prostate Cancer

Prostate Cancer

Belgium, Germany, Hungary, Netherlands, Romania, Russian Federation, South Africa
Ferring Pharmaceuticals

Completed

Extension Study Investigating the Long-Term Safety of Degarelix One-Month Depots in Patients With Prostate Cancer

Prostate Cancer

United States, Canada
Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator...

Active, not recruiting

Pharmacogenomics IND EXEMPT SNP Clinical Study - Abiraterone and Single Nucleotide Polymorphisms (Drugs-SNPs)

Prostate Cancer

United States
University of Colorado, Denver

Active, not recruiting

Ovarian Hormone Regulation of Central and Cerebrovascular Hemodynamics (NoMEN Study)

Menopause | Aging | Estrogen Deficiency | Women

United States
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Pharmacokinetics of Abiraterone in Healthy Chinese Male Participants

Healthy

China
Cougar Biotechnology, Inc.

Completed

A Study to Assess the Relative Bioavailability of Two Abiraterone Acetate Suspension Formulations Compared to the Abiraterone Acetate Tablet Formulation in Healthy Adult Volunteers

Healthy Volunteers
Cougar Biotechnology, Inc.

Completed

A Study to Determine the Effect of Food on the Pharmacokinetics of Abiraterone Acetate in Healthy Male Patients

Healthy Volunteers
Cougar Biotechnology, Inc.

Completed

A Pharmacokinetics Study to Assess Abiraterone Acetate Capsule and Tablet Formulations in Patients With Prostate Cancer

Prostate Neoplasms

United Kingdom, United States
Janssen Research & Development, LLC

Completed

A Comparative Study of Bioavailability of 3 New Abiraterone Acetate Tablets With Current Commercial Tablet

Healthy Participants

United States
M.D. Anderson Cancer Center
Blue Earth Therapeutics

Recruiting

NeoAdjuvant Theranostic Lutetium Study: The Nautilus Trial

Prostate Cancer

United States
Kenneth Pienta, MD
Prostate Cancer Foundation Norway

Withdrawn

A Phase II Neoadjuvant Study of Enzalutamide, Abiraterone Acetate, Dutasteride and Degarelix in Men With Localized Prostate Cancer Pre-prostatectomy

Prostate Cancer | Localized Prostate Cancer

United States
Bayer

Completed

A Randomized Phase IIa Efficacy and Safety Study of Radium-223 Dichloride With Abiraterone Acetate or Enzalutamide in Metastatic Castration-resistant Prostate Cancer (CRPC)

Prostatic Neoplasms

United States
Assistance Publique - Hôpitaux de Paris
Janssen, LP

Completed

Study of Dose Escalation of Abiraterone Actetate in Prostate Cancer (OPTIMABI)

Prostate Cancer

France
Janssen Research & Development, LLC

Completed

Bioequivalence Study of Abiraterone Acetate Coated and Uncoated Tablet Formulations in Healthy Male Participants

Healthy

United States
The Affiliated Hospital of Qingdao University

Completed

Bioequivalence of Abiraterone Acetate Tablets in Healthy Chinese Volunteers

Healthy Volunteers

China
Cougar Biotechnology, Inc.

Completed

A Pharmacokinetic Study of Abiraterone Acetate in Male Participants With Impaired Renal Function Compared to Individuals With Normal Renal Function

Renal Insufficiency

United States
Fundación Pública Andaluza para la gestión de la...

Completed

Pharmacokinetic Food-effect Study of Abiraterone Acetate (AA) in Castration Resistant Prostate Cancer (ABIFOOD01)

Prostate Cancer

Spain
West China Hospital

Not yet recruiting

TQB3616 Capsules Combined With Abiraterone Acetate Plus Prednisone in Metastatic Castration-Resistant Prostate Cancer

Prostatic Neoplasms, Castration-Resistant | Drug Therapy, Combination

China
Ferring Pharmaceuticals

Terminated

A Degarelix Trial in Patients With Prostate Cancer

Prostate Cancer

United States, Netherlands, United Kingdom, Hungary, Belgium, Czech Republic, Finland, Germany, Mexico, Poland, Romania, Ukraine, Canada
Royal Marsden NHS Foundation Trust
University College, London; The Leeds Teaching Hospitals NHS Trust; Belfast Health... and other collaborators

Unknown

Targeted Radiotherapy in Androgen-suppressed Prostate Cancer Patients. (TRAP)

Prostate Cancer | Metastasis | Toxicity Due to Radiotherapy | Circulating Tumour DNA

United Kingdom
Universität des Saarlandes

Completed

Trial of Abiraterone Acetate Plus LHRH-therapy Versus Abiraterone Acetate Sparing LHRH-therapy in Patients With Progressive Chemotherapy-naïve Castration-resistant Prostate Cancer (SPARE) (SPARE)

Prostate Cancer

Germany
Sun Pharmaceutical Industries Limited

Completed

A Study to Evaluate Serum Testosterone Levels in Patients With Metastatic Castration-Resistant Prostate Cancer (STAAR)

Prostate Cancer

United States
Ferring Pharmaceuticals

Completed

A Trial of Degarelix in Patients With Prostate Cancer

Prostate Cancer

United States, Canada, Netherlands, United Kingdom, Belgium, Germany, Hungary, Czech Republic, Finland, Mexico, Poland, Romania, Russian Federation, Ukraine
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase III Study of Fuzuloparib Combined With Abiraterone Acetate and Prednisone (AA-P) Versus Placebo Combined With AA-P as First-Line Treatment in Patients With Metastatic Castration-Resistant Prostate Cancer

Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Korea, Republic of, United States, Spain, France, Belgium, China, Taiwan, United Kingdom, Australia, Czechia, Hungary, Poland, Russian Federation
Fudan University

Recruiting

Enhanced Systemic Combined With Local Treatment for Primary and Metastatic Lesions in Oligo-metastatic Prostate Cancer

Prostate Cancer

China
Massachusetts General Hospital

Active, not recruiting

Abiraterone Acetate for Castrate Resistant Prostate Cancer

Prostate Cancer

United States
Cougar Biotechnology, Inc.

Completed

A Study to Assess the Effect of Abiraterone Acetate in Male Participants With Mild or Moderate Hepatic Impairment Compared to Matched Control Participants With Normal Hepatic Function

Prostate Cancer

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study Examining Doses of Abiraterone Acetate in Adult Women With 21-Hydroxylase Deficiency

21-hydroxylase Deficiency

United States
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

Dalpiciclib Isethionate Tablets Combined With Abiraterone Acetate Tablets (I) and Prednisone Tablets (AA-P) Versus Placebo Combined With AA-P in Treatment of High-volume, Metastatic, Hormone-sensitive Prostate Cancer (mHSPC)

High-volume, Metastatic, Hormone-sensitive Prostate Cancer (mHSPC)
Janssen Research & Development, LLC

Completed

A Study of Abiraterone Acetate Plus Low-Dose Prednisone Plus Androgen Deprivation Therapy (ADT) Versus ADT Alone in Newly Diagnosed Participants With High-Risk, Metastatic Hormone-Naive Prostate Cancer (mHNPC)

Prostate Neoplasms

Canada, France, Poland, Ukraine, United Kingdom, China, Belgium, Spain, Argentina, Colombia, Israel, Mexico, Portugal, Bulgaria, Germany, Malaysia, Romania, South Africa, Turkey, Korea, Republic of, Japan, Australia, Netherlands, Sweden, New Zealand and more
Cougar Biotechnology, Inc.

Completed

A Safety and Efficacy Study of Abiraterone Acetate in Participants With Prostate Cancer Who Have Failed Hormone Therapy

Prostatic Neoplasms

United Kingdom
Zhongnan Hospital

Active, not recruiting

Effects of Metabolic Enzymes and Transporter Gene Polymorphisms on the Pharmacokinetics and Metabolism of Oral Abiraterone Acetate in Healthy Chinese Adults

Pharmacokinetic | Abiraterone Acetate | Plasma Concentration | Gene Polymorphism | Metabolic Analysis

China
University of Chicago
National Cancer Institute (NCI)

Completed

Food Effect Study of Abiraterone Acetate for Treatment of Patients With Castration-Resistant Prostate Cancer

Castration-resistant Prostate Cancer | Stage IV Prostate Cancer

Singapore, United States
Guangzhou University of Traditional Chinese Medicine
Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Unknown

A Pilot Study of Hormonal Therapy Combined With Central Memory T Cells (Tcm) for Patients With Advanced Prostate Cancer

Prostatic Neoplasms

China
Karolinska Institutet
The Swedish Research Council; AstraZeneca; Janssen Pharmaceutica N.V., Belgium; Kom Op Tegen Kanker and other collaborators

Recruiting

ProBio: A Biomarker Driven Study in Patients With Metastatic Prostate Cancer (ProBio)

Metastatic Castration-resistant Prostate Cancer (mCRPC) | Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)

Sweden, Belgium, Switzerland, Norway
Exelixis

Terminated

Study of Cabozantinib in Combination With Abiraterone in Chemotherapy-Naïve Subjects With Bone-Metastatic Castration-Resistant Prostate Cancer

Prostatic Neoplasms | Prostate Cancer | Castration Resistant Prostate Cancer

United States
Urology of Virginia
Ferring Pharmaceuticals

Completed

Initiation of Androgen Deprivation Therapy for Prostate Cancer Using Degarelix Followed by Leuprolide

Prostate Cancer

United States
University Health Network, Toronto

Completed

Biomarkers of Androgen Response and Resistance In Evolution During a Rising PSA (BARRIER-P)

Castration-resistant Prostate Cancer

Canada
Jianbin Bi

Not yet recruiting

Rezvilutamide Plus Abiraterone for Metastatic Hormone-sensitive Prostate Cancer (RASTOM)

Metastatic Hormone-Sensitive Prostate Cancer
Pfizer
Astellas Pharma Inc

Active, not recruiting

A Study to Learn About the Study Medicines Called Enzalutamide and Abiraterone in People With Metastatic Castration-resistant Prostate Cancer

Prostatic Neoplasms, Castration-Resistant

United States
Aurelius Omlin
University Hospital, Basel, Switzerland; Cantonal Hospital of St. Gallen

Terminated

Abiraterone-Rechallenge Study for CRPC Patients (ABI-RE)

Prostate Cancer

Switzerland
Cancer Research UK

Completed

Abiraterone Acetate in Treating Postmenopausal Women With Advanced or Metastatic Breast Cancer

Breast Cancer

United Kingdom
Dana-Farber Cancer Institute
Janssen Research & Development, LLC

Active, not recruiting

Study of Abiraterone Acetate Without Exogenous Glucocorticoids in Men With Castration-resistant Prostate Cancer

Castration-resistant Prostate Cancer

United States
Pfizer

Completed

Enzalutamide vs. Abiraterone in Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer (mCRPC)

Prostatic Neoplasms, Castration-Resistant

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

Comparative Study of Abiraterone Acetate Tablets (I) or ZYTIGA® in Patients With Metastatic Castration-resistant Prostate Cancer

Metastatic Castration-resistant Prostate Cancer (mCRPC)

China
University of California, San Francisco
Johnson & Johnson; Cougar Biotechnology, Inc.

Completed

Abiraterone Post Ketoconazole for Prostate Cancer

Prostate Cancer

United States
Carolina Research Professionals, LLC
Bayer

Completed

Open Label Phase Two Trial of Radium Ra 223 Dichloride With Concurrent Administration of Abiraterone Acetate Plus Prednisone in Symptomatic Castration-Resistant (Hormone-Refractory) Prostate Cancer Subjects With Bone Metastasis (eRADicAte)

Prostate Cancer

United States
Duke University

Completed

Men With Metastatic Castrate-Resistant Prostate Cancer Treated With Either Sipuleucel-T (Provenge®), Abiraterone Acetate (Zytiga®) or Enzalutamide (Xtandi®) Undergoing Cardiopulmonary EXercise Testing (PEAX)

Prostate Cancer

United States

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