Search clinical trials for: Active Caspofungin

Total 99478 results

Pfizer

Terminated

An Evaluation Of The Effectiveness And Safety Of Anidulafungin Compared To Caspofungin For The Treatment Of Deep Tissue Infection Due To Candida

Candidiasis | Fungemia

Belgium, United States, Canada, Switzerland, Netherlands, Bulgaria, Portugal, Romania, Russian Federation
Pfizer

Terminated

An Evaluation Of The Effectiveness And Safety Of Anidulafungin Compared To Caspofungin For The Treatment Of Serious Fungal Infection Due To Candida In Patients With A Dysfunctional Immune System

Candidiasis | Fungemia | Neutropenia

Poland, Russian Federation, France, Bosnia and Herzegovina, Italy, Slovakia
Assistance Publique - Hôpitaux de Paris

Completed

Pharmacokinetics of Caspofungin in Burn Patients (Caspo-brûlés)

Thermal Injury

France
National Cancer Institute (NCI)

Completed

Caspofungin Acetate in Treating Children With Fever and Neutropenia

Sarcoma | Lymphoma | Kidney Cancer | Leukemia | Neutropenia | Neuroblastoma | Infection | Fever, Sweats, and Hot Flashes

United States
Merck Sharp & Dohme LLC
Mycoses Study Group

Terminated

Pilot Feasibility Study With Patients Who Are at High Risk For Developing Invasive Candidiasis in a Critical Care Setting (MK-0991-067)

Invasive Candidiasis
Merck Sharp & Dohme LLC

Completed

Open, Pharmacokinetic Study of Caspofungin in Neonates and Infants (0991-058)

Candidiasis
Cttq

Completed

Empiric Therapy of Patients With Persistent Fever and Agranulocytosis Using Caspofungin

Fungal Infection

China
Radboud University Medical Center

Completed

Pharmacokinetics of Caspofungin (Cancidas ®) Given Intravenously as Therapy to Patients With an Invasive Fungal Infection in the Intensive Care Unit - a Search for Co-variates (CASCADE)

Invasive Fungal Infection

Netherlands
University of Cologne

Completed

Caspofungin Maximum Tolerated Dose in Patients With Invasive Aspergillosis

Invasive Aspergillosis

Germany, Belgium
The First Affiliated Hospital of Guangzhou Medical...
Merck Sharp & Dohme LLC

Unknown

Efficacy and Safety of Caspofungin for Invasive Pulmonary Aspergillosis Underlying Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease | Invasive Pulmonary Aspergillosis

China
European Organisation for Research and Treatment...

Completed

Empirical Versus Preemptive Antifungal Therapy

Myelodysplastic Syndromes | Leukemia | Fungal Infection

Belgium, Netherlands, Germany, France, Czechia, Slovakia
Werner J. Heinz
Merck Sharp & Dohme LLC

Completed

Pharmacokinetic, Safety and Efficacy of Intermittent Application of Caspofungin for Antifungal Prophylaxis (CASPHYLAX)

Fungal Infection

Germany
European Organisation for Research and Treatment...

Completed

Caspofungin Acetate in Treating Aspergillosis in Patients With Hematologic Cancer or in Patients Who Have Undergone a Stem Cell Transplant

Cancer

France, Switzerland, Italy, Slovakia, Belgium, Germany, Turkey
Merck Sharp & Dohme LLC

Completed

A Clinical Study of MK0991 (Caspofungin) in Japanese Patients With Deep-seated Candida or Aspergillus Infections (0991-062)(COMPLETED)

Fungal Infection
Merck Sharp & Dohme LLC

Completed

A Study of Caspofungin Acetate (MK0991) for the Treatment of Esophageal Candidiasis or Invasive Candidiasis in Chinese Adults (MK-0991-066)

Fungal Infection
Merck Sharp & Dohme LLC

Completed

Open, Pharmacokinetic Study of Caspofungin Acetate in Immunocompromised Young Children With Febrile Neutropenia (0991-042)

Fungal Infection
Fujian Shengdi Pharmaceutical Co., Ltd.

Recruiting

A Trial of Intravenous HRS9432 in the Treatment of Subjects With Candidemia and/or Invasive Candidiasis

Patients With Candidemia and/or Invasive Candidiasis

China
Merck Sharp & Dohme LLC

Completed

A 28 - 90 Days Study to Evaluate the Safety, Tolerability, and Efficacy of Caspofungin Injection as Empirical Therapy in Indian Adults With Persistent Fever and Neutropenia (0991-053)(COMPLETED)

Fungal Infection
Merck Sharp & Dohme LLC

Completed

A Multicenter, Randomized, Double-Blind, Comparative Study to Evaluate the Safety, Tolerability, and Efficacy of 2 Dosing Regimens of an Antifungal Drug in the Treatment of Fungal Infections in Adults (0991-801)(COMPLETED)

Invasive Candidiasis
Erasme University Hospital

Completed

Pharmacokinetics of Caspofungin After One Dose in Patients With Liver Failure

Bacterial Infections and Mycoses | Liver Disease

Belgium
Merck Sharp & Dohme LLC

Completed

Documented Candida or Aspergillus Infections in Pediatric Patients (0991-043)

Candidiasis | Aspergillosis
Astellas Pharma Inc

Completed

Trial of Two Dosing Regimens of Micafungin Versus Caspofungin for the Treatment of Esophageal Candidiasis

Candidiasis, Oral

Argentina, South Africa, Brazil, Peru
Centre Hospitalier Universitaire de Nīmes

Completed

Pharmacokinetic Study on Echinocandins for Patients With Septic Shock Following Secondary Peritonitis

Septic Shock | Peritonitis

France, Australia
Merck Sharp & Dohme LLC

Completed

Caspofungin for the Treatment of Non-blood Candida Infections (0991-045)

Candidiasis
Shanghai Jiao Tong University School of Medicine

Unknown

Caspofungin Based Combined Anti-fungal Therapy for Proven or Probable Invasive Fungal Infection

Leukemia | Transplantation, Hematopoietic Stem Cell

China
Merck Sharp & Dohme LLC

Completed

Evaluate the Safety and Efficacy of Caspofungin Acetate as Empirical Therapy in Chinese Adults With Persistent Fever and Neutropenia (0991-055)

Fungal Infection
Shanghai General Hospital, Shanghai Jiao Tong University...

Not yet recruiting

To Evaluate the Efficacy and Safety of Micafungin in Preventing Invasive Mycosis After Liver Transplantation

Liver Transplantation
Gilead Sciences

Completed

COMBISTRAT: AmBisome® in Combination With Caspofungin for the Treatment of Invasive Aspergillosis

Invasive Aspergillosis

France
Merck Sharp & Dohme LLC

Completed

MK0991 Versus Amphotericin B for Empirical Therapy in Febrile, Neutropenic Pediatric Patients (0991-044)

Neutropenia | Fever
Centre Hospitalier Universitaire de Saint Etienne
Merck Sharp & Dohme LLC

Completed

Evaluation of the Pharmacokinetics of Caspofungin in ICU Patients (CaspoKin)

Shock

France
Texas Tech University Health Sciences Center
University of Texas Southwestern Medical Center; National Center for Research...

Completed

Effect of Weight and/or Obesity on Caspofungin Drug Concentrations

Obesity | Fungal Infection

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment

Cancer

United States
University Hospital Muenster
Merck Sharp & Dohme LLC; Gilead Sciences

Completed

A Study of Caspofungin, Liposomal Amphotericin B or the Combination of Both for Patients After Stem-Cell Transplantation

Hematopoietic Stem Cell Transplantation | Fungus Diseases

Germany
Children's Hospital of Fudan University

Not yet recruiting

PK/PD of Caspofungin in Children Severe Infection

Pharmacokinetics | Infection, Fungal

China
Medical University of Lublin

Unknown

Pharmacokinetics of Caspofungin

Critical Illness | Septic Shock | Fungal Infection
National Cancer Institute (NCI)

Completed

Caspofungin to Prevent Candidiasis in Adults in Hospital Intensive Care Units

Candidiasis

United States
Merck Sharp & Dohme LLC

Completed

A Study of the Side Effects of L-743,872 in Men With Candidal Esophagitis

HIV Infections | Candidiasis, Esophageal

United States
University Medical Center Groningen

Completed

Optimal Dosage of Caspofungin in Critically Ill Patients

Critically Ill | Suspected Invasive Candidiasis

Netherlands
Azienda Ospedaliera di Padova
Merck Sharp & Dohme LLC

Unknown

Caspofungin as Prophylaxis in High Risk Liver Transplantation Recipients (CPHRLTX)

Mycoses | Fungemia

Italy
Northern Italy Leukemia Group

Completed

Prophylaxis of Fungal Invasive Infections in Leukemia (PROFIL-C)

Invasive Pulmonary Aspergillosis

Italy
PETHEMA Foundation
GTEI; SEMICYUC

Completed

Acetato de Caspofungin (Cancidas®) in the Treatment of Fungal Infection

Candidiasis | Aspergillosis

Spain
Shandong University

Completed

Population Pharmacokinetics and Dose Optimization of Caspofungin in Adolescents

Invasive Fungal Infections

China
Merck Sharp & Dohme LLC

Completed

A Study of Caspofungin (MK-0991) in Japanese Children and Adolescents With Documented Candida or Aspergillus Infections (MK-0991-074)

Candidiasis, Invasive | Aspergillosis | Candidiasis, Esophageal
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Unknown

Pharmacokinetics and Pharmacodynamics of Caspofungin (Cancidas ®) and Drug Tolerance of Fungi to Patients With an Invasive Fungal Infection in the Intensive Care Unit

Invasive Fungal Infection
National Institute of Allergy and Infectious Diseases...

Terminated

Caspofungin Study for Fungal Infections in Adults in Critical Care Settings

Candidiasis

United States
Merck Sharp & Dohme LLC

Terminated

Safety and Effectiveness of Giving L-743,872 to Patients With Thrush That Has Not Been Cured With Fluconazole

HIV Infections | Candidiasis, Oral

United States
Careggi Hospital

Completed

Pharmacokinetics/Pharmacodynamics (PK/PD) of Caspofungin in Intensive Care Unit (ICU) Patients. An Open Observational Study for Antifungal Treatment's Optimization

Critical Illness | Infection
Mycoses Study Group
Merck Sharp & Dohme LLC

Completed

Randomized Study of Caspofungin Prophylaxis Followed by Pre-emptive Therapy for Invasive Candidiasis in the Intensive Care Unit (ICU) (MSG-01)

Invasive Candidiasis

United States
Merck Sharp & Dohme LLC

Completed

MK0991 in Combination With Standard Antifungal Agent(s) for the Treatment of Salvage Invasive Aspergillosis (0991-037)

Aspergillosis
Gary E. Stein, Pharm.D.
Astellas Pharma US, Inc.

Completed

Comparison of Candida Eradication and Serum Cidal Activity of Echinocandins

Candidemia

United States

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