Search clinical trials for: Active comparator: Niraparib

Total 100226 results

Fisher and Paykel Healthcare

Completed

Efficacy of NIV Masks in COPD

COPD

New Zealand
Mayo Clinic

Completed

Understanding the Pathophysiology and Effects of Diaphragmatic Breathing in Upright Gastroesophageal Reflux

GERD

United States
VertiFlex, Incorporated

Completed

The STEPS - Totalis™ Trial

Lumbar Spinal Stenosis

United States
Hoffmann-La Roche

Terminated

A Study Investigating the Safety and Efficacy of Lampalizumab Intravitreal Injections in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (SPECTRI)

Geographic Atrophy

United States, United Kingdom, Netherlands, Germany, Belgium, Poland, Spain, Argentina, Australia, Hungary, Italy, Portugal, France, Turkey, Austria, Russian Federation, Mexico, Peru, Denmark, Slovakia, Sweden, Switzerland
Hospital de Clinicas de Porto Alegre

Completed

Pharmaceutical Care in the Reduction of Readmission Rates in Diabetes Melitus

Diabetes Mellitus
Merck Sharp & Dohme LLC

Completed

Safety and Tolerability of Odanacatib (0822-059)

Osteoporosis
Autifony Therapeutics Limited

Completed

Efficacy and Safety of AUT00063 Versus Placebo in Age-Related Hearing Loss (CLARITY-1)

Age-Related Hearing Loss

United States
Eisai Inc.

Completed

A Efficacy and Safety Study of Adjunctive Perampanel in Primary Generalized Tonic Clonic Seizures

Seizure Disorder Generalized Tonic Clonic
Tufts University
Boston University

Completed

Effects of Almonds on Vascular Reactivity in Patients With Coronary Artery Disease

Cardiovascular Diseases | Hypertension | Heart Disease | Endothelial Dysfunction | Vascular Disease

United States
Ono Pharma USA Inc

Terminated

Study to Evaluate the Effects of ONO-2952 on Pain Perception Produced by Rectal Distention in Female Subjects With Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D) (RESTORE)

Irritable Bowel Syndrome (IBS)

United States
Merck Sharp & Dohme LLC

Completed

A Research Study of MK0633 in Patients With Chronic Obstructive Pulmonary Disease (COPD)(0633-009)(COMPLETED)

Chronic Obstructive Pulmonary Disease (COPD)
Merck Sharp & Dohme LLC

Completed

MK0557 for the Treatment of Cognitive Impairment in Patients With Schizophrenia (0557-027)

Schizophrenia | Paranoid Schizophrenia
Merck Sharp & Dohme LLC

Completed

MK0249 for the Treatment of Cognitive Impairment in Patients With Schizophrenia (0249-016)

Paranoid Schizophrenia
Merck Sharp & Dohme LLC

Completed

A Pharmacokinetic Study of MK-0941 After Multiple Daily Doses in Subjects With Type 2 Diabetes (MK-0941-012)(COMPLETED)

Diabetes Mellitus, Type 2
Abbott

Completed

A Study to Evaluate the Safety and Tolerability of ABT-614 and Its Effect on Kidney Function in Subjects With Type 2 Diabetes and Chronic Kidney Disease With Protein in Their Urine.

Type 2 Diabetics, Chronic Kidney Disease, Protein in Urine

United States
Merck Sharp & Dohme LLC

Completed

V260 Study: Concomitant Use of V260 and INFANRIX™ Hexa in Healthy Infants (V260-010)

Rotavirus Disease
Merck Sharp & Dohme LLC

Completed

A Study of ProQuad in Healthy 4 to 6 Year Old Children (V221-014)

Measles | Rubella | Mumps | Varicella
Ibrahim Halil Sahin
GlaxoSmithKline

Not yet recruiting

Niraparib and Dostarlimab for Patients With MMR-D/MSI-H Colorectal Cancers

MMR-D/MSI-H Colorectal Cancers

United States
H. Lee Moffitt Cancer Center and Research Institute
GlaxoSmithKline

Recruiting

Study of the Combination Dostarlimab With Niraparib In Patients With Penile Carcinoma

Penile Carcinoma

United States
Peking Union Medical College Hospital
Zai Lab (Shanghai) Co., Ltd.

Not yet recruiting

A Phase II Trial to Explore Niraparib and Anlotinib Maintenance Retreatment in Platinum-Sensitive Recurrent Ovarian Cancer Patients Previously Treated With PARPi (t)

Epithelial Ovarian Cancer
Merck Sharp & Dohme LLC

Terminated

A Phase I Study of MK-4827 for Treatment of Solid Tumors (MK-4827-005)

Neoplasms | Solid Tumors
Theravance Biopharma

Completed

Single Ascending Dose Study of TD-0714 in Healthy Subjects

Healthy

United States
Merck Sharp & Dohme LLC

Completed

A Study of Single Dose MK-3614 (MK-3614-001)(COMPLETED)

Hypertension
Fervent Pharmaceuticals
Iqvia Pty Ltd

Completed

FP-101 for the Treatment of Hot Flashes in Postmenopausal Women

Hot Flashes

United States
Sean Savitz

Withdrawn

Mesenchymal Stromal Cells for Ischemic Stroke (SAMCIS)

Ischemic Stroke
Abide Therapeutics

Completed

A Study to Evaluate the Effects of ABX-1431 on Patients With Tourette Syndrome

Tourette Syndrome | Chronic Motor Tic Disorder

Germany
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Multiple Doses Escalation Study of SHR0302 in Rheumatoid Arthritis (RA) Patients

Rheumatoid Arthritis

China
Autifony Therapeutics Limited
University of Nottingham

Completed

Evaluating Possible Improvement in Tinnitus Severity After 28 Days Dosing of the Study Drug AUT00063 Compared to Placebo (QUIET-1)

Tinnitus, Subjective

United Kingdom
Merck Sharp & Dohme LLC

Completed

Single Doses of MK-0941 in Type 2 Diabetics (MK-0941-027)

Type 2 Diabetes
Merck Sharp & Dohme LLC

Completed

Treatment of Patients With Anxiety Disorder (0777-022)

Generalized Anxiety Disorder
Merck Sharp & Dohme LLC

Completed

A Study to Assess the Effects of a Light Breakfast on the Safety, Tolerability, and Pharmacokinetics of Odanacatib (MK0822)

Osteoporosis
Johnson & Johnson Pharmaceutical Research & Development...

Terminated

Effectiveness and Safety Study for JNJ-18054478 in Asthma Patients.

Asthma

United States, Costa Rica, India
Universidade Federal de Goias

Completed

Back Squat Exercise Treatment for Low Back Pain: Clinical Trial

Low Back Pain | Postural Low Back Pain | Muscle Strength | Spine Degeneration | Visceral Obesity | Spine Disease | Spine Deformity

Brazil
Weill Medical College of Cornell University

Withdrawn

Efficacy Study on the Transfer of Adenovirus With the CD40 Ligand Gene (AdcuCD40L) to Patients With Esophageal Carcinoma (cd40)

Esophageal Neoplasms
Riphah International University

Recruiting

Effects of Manual IC With and Without SCS on SCM Tightness With FHP

Neck Pain

Pakistan
VA Office of Research and Development
United States Military Academy

Completed

Heated Vest for Persons With Spinal Cord Injury

Spinal Cord Injuries

United States
University of South Florida

Completed

Optimal Metabolic Health Through Continuous Glucose Monitoring (CGM)

Metabolic Syndrome

United States
Yuhan Corporation

Completed

BE Study of Two Formulations of Rivaroxaban 2.5 mg in Healthy Subjects

Healthy Volunteer

Korea, Republic of
Merck Sharp & Dohme LLC

Completed

An Investigational Drug Study in Patients With Type 2 Diabetes Mellitus (MK0431-023)

Diabetes Mellitus, Type 2
McNeil AB

Completed

Cumulative Skin Irritation Potential of a New 15 mg Nicotine Patch

Smoking Cessation

Germany
Prof. Patrick Petignat
Dschang District Hospital

Recruiting

Home-based Cervical Cancer Screening Project (CASAHO)

Cervical Cancer

Cameroon
University Hospital Marburg

Recruiting

IF-MCT 16:8: Investigating the Influence of Intermittent Fasting With and Without MCTs in Patients With Drug-resistant Epilepsy (IF-MCT16:8)

Epilepsy | Intermittent Fasting

Germany
Dr. Reddy's Laboratories Limited

Completed

Bioavailability of DFN-15 at 3 Different Doses vs. Comparator and to Determine Dose-proportionality of DFN-15 in Fasting Healthy Adults

Healthy

United States
Posit Science Corporation

Completed

Computerized Attention Training for Individuals With Acquired Brain Injury

Stroke | Acquired Brain Injury | Hemispatial Neglect

United States
University Hospital Plymouth NHS Trust

Completed

High Definition CT Coronary Angiography Accuracy Trial

Coronary Artery Disease

United Kingdom
Beijing Ditan Hospital

Completed

A Study to Assess the Efficacy of HH-120 Nasal Spray for Prevention of SARS-CoV-2 Infection in Adult Close Contacts of Individuals Infected With SARS-CoV-2

SARS-CoV-2 Infection

China
AGO Research GmbH
GlaxoSmithKline

Not yet recruiting

Study to Estimate Efficacy of Combining Dostarlimab and Niraparib in Relapsed EOC After Treatment With PARPi

Primary Peritoneal Cancer | Recurrent Ovarian Cancer | Recurrent Fallopian Tube Cancer
University of Oklahoma
Tesaro, Inc.

Recruiting

Niraparib in Combination With Dostarlimab in Patients With Recurrent or Progressive Cervix Cancer (STAR)

Recurrent Cervix Cancer | Progressive Cervix Cancer

United States
Massachusetts General Hospital
Tesaro, Inc.

Completed

Niraparib + Dostarlimab + RT in Pancreatic Cancer

Pancreatic Cancer | Metastatic Pancreatic Cancer

United States
Merck Sharp & Dohme LLC

Completed

A Study That Will Evaluate Ketogenesis and Glucose-Dependent Insulin Secretion Methodologies in Healthy Male Subjects (MK-0000-159)(COMPLETED)

Obesity

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