Search clinical trials for: Adjuvants, Immunologic

Total 39582 results

AstraZeneca

Active, not recruiting

Assessment of Efficacy and Safety of Durvalumab Plus BCG Compared to the Standard Therapy With BCG in Non-muscle Invasive Bladder Cancer (POTOMAC)

Non-muscle-invasive Bladder Cancer

France, Spain, Belgium, Canada, Poland, Germany, Japan, Russian Federation, United Kingdom, Austria, Australia, Netherlands
National Institute of Allergy and Infectious Diseases...

Withdrawn

Phase I Dose Escalation SARS-CoV Recombinant S Protein, With and Without Adjuvant, Vaccine Study

SARS

United States
University of Virginia
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Metastatic Melanoma

Melanoma (Skin)

United States
Oncothyreon Canada Inc.

Completed

Vaccine Therapy in Treating Women With Metastatic Breast Cancer

Breast Cancer

Canada
St George's, University of London
Novartis Vaccines; European Union; Richmond Pharmacology Limited

Terminated

Safety Study Of Nasal HIV Vaccine Adjuvanted With LTK63

HIV Infections

United Kingdom
The Cleveland Clinic

Completed

A Phase I - II Safety Study of Filgrastim (Neupogen) to Improve Left Ventricular Function After Severe Acute Myocardial Infarction

Acute Myocardial Infarction

United States
Immunobiology Research Institute

Completed

Double Blind Study of Thymopentin Effects on Patients With HIV-1 Infection

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Study of Stem Cells and Filgrastim

HIV Infections

United States
Azidus Brasil

Completed

Evaluation of Pharmacokinetic and Pharmacodynamic Parameters of Filgrastim (G-CSF)Produced by Blausiegel Indústria e Comércio Ltda. Compared to Granulokine Produced by Produtos Roche Químicos e Farmacêuticos S/A.

Healthy Subjects

Brazil
Azienda Ospedaliera San Giovanni Battista

Unknown

Efficacy of Biosimilar Filgrastim on the Mobilization of Hematopoietic Stem Cell CD34+ (Cluster of Differentiation 34) and on the Kinetic Engraftment

Blood Diseases

Italy
Herbert Irving Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

G-CSF in Stimulating Peripheral Stem Cells for Autologous Stem Cell Transplant in Treating Patients With Chronic Phase Chronic Myeloid Leukemia in Complete Remission

Leukemia

United States
Centre Francois Baclesse

Completed

G-CSF in Preventing Neutropenia in Women Receiving Chemotherapy for Breast Cancer

Breast Cancer | Neutropenia | Chemotherapeutic Agent Toxicity

France
Immunobiology Research Institute

Completed

A Study of Thymopentin Effects on HIV-1 Infectivity of Blood Mononuclear Cells and Semen in HIV Infected Patients

HIV Infections

United States
Craig L Slingluff, Jr
National Cancer Institute (NCI)

Completed

Vaccine Therapy With or Without Imiquimod in Treating Patients Who Have Undergone Surgery for Stage II, Stage III, or Stage IV Melanoma

Melanoma (Skin)

United States
Amgen

Completed

Open-Label Trial of Peripheral Blood Progenitor Cell (PBPC) Mobilization by Filgrastim in Normal Donors

Normal PBPC Donors
WiSP Wissenschaftlicher Service Pharma GmbH
Ludwig-Maximilians - University of Munich; Chugai Pharma GmbH

Completed

Predictive Value of the "Cytocapacity Test" Patients With Lymphoproliferative Diseases and High-dose Therapy (CU01)

Hodgkin's Disease | Non-Hodgkin Lymphomas | Multiple Myelomas
Centre National de Greffe de Moelle Osseuse

Unknown

Trial of Filgrastim Versus Placebo Following Allogeneic Bone Marrow Transplantation

Graft vs Host Disease

Tunisia
National Center for Research Resources (NCRR)
James Whitcomb Riley Hospital for Children

Completed

Phase II Pilot Study of Granulocyte Colony-Stimulating Factor for Inherited Bone Marrow Failure Syndromes

Thrombocytopenia | Dyskeratosis Congenita | Fanconi's Anemia | Shwachman Syndrome
Amgen

Completed

A Randomized, Controlled, Multicenter Trial of Filgrastim (Recombinant-Methionyl Human Granulocyte Colony Stimulating Factor; G-CSF) for the Prevention of Grade 4 Neutropenia in Patients With HIV Infection.

HIV Infections | Cytopenias

United States, Canada
U.S. Army Medical Research and Development Command

Completed

TDENV PIV and LAV Dengue Prime-boost Strategy

Dengue

United States
National Cancer Institute (NCI)

Terminated

p53 Vaccine for Ovarian Cancer

Ovarian Neoplasm

United States
NYU Langone Health
MOUNT SINAI HOSPITAL

Withdrawn

A Toll-like Receptor Agonist as an Adjuvant to Tumor Associated Antigens (TAA) Mixed With Montanide ISA-51 VG With Bevacizumab for Patients With Recurrent Glioblastoma

Glioma | Glioblastoma

United States
Providence Cancer Center, Earle A. Chiles Research...
National Cancer Institute (NCI)

Completed

Fludarabine Followed by Vaccine Therapy and White Blood Cell Infusions in Treating Patients With Unresectable or Metastatic Melanoma

Melanoma (Skin)

United States
Seqirus

Completed

Phase 3 Safety and Immunogenicity Study of aQIV in Elderly Adults

Influenza, Human

United States
National Institute of Allergy and Infectious Diseases...

Completed

Dose, Safety, Tolerability, and Immunogenicity of an HIV-1 Vaccine, VRC-HIVRGP096-00-VP, With Alum in Healthy Adults

Human Immunodeficiency Virus (HIV) | Human Immunodeficiency Virus Prevention

United States
Nina Bhardwaj
Cancer Research Institute, New York City

Completed

Randomized, Double Blind, Placebo-controlled Topical Resiquimod Adjuvant for NY-ESO-1 Protein Vaccination

Tumors

United States
CellProthera

Recruiting

Donation of Whole Blood by Healthy Volunteers After Mobilisation by Haematopoietic Growth Factor (Rhu-G-CSF = Granocyte) (CARDIOSTEM)

Healthy Volunteers

France
Sun Yat-sen University

Not yet recruiting

Long-term Prognosis of Patients With Sepsis After Immunotherapy

Long-term Effects of Thymosin Alpha 1 Treatment
RenJi Hospital

Unknown

Immunotherapy for Elderly Patients With Chronic Osteoporotic Pain

Osteoporotic Pain

China
Millennium Pharmaceuticals, Inc.

Terminated

Surveillance Study of Patients With Newly Diagnosed Osteosarcoma

Osteosarcoma

Austria
Anglo Celtic Cooperative Oncology Group
Scottish Cancer Therapy Network

Unknown

Filgrastim or Pegfilgrastim in Preventing Neutropenia in Women Receiving Chemotherapy Following Surgery for Breast Cancer

Breast Cancer | Neutropenia

United Kingdom
Amgen

Completed

Trial Comparing Pegfilgrastim With Filgrastim as an Adjunct to Chemotherapy for Acute Myeloid Leukaemia (AML)

Myeloid Leukemia
Fudan University

Recruiting

Thymosin-alpha 1 for Adjuvant Treatment After Radical Resection of High-risk Stage II and III Colorectal Cancer

Stage III Colorectal Cancer | Stage II Colorectal Cancer

China
University of Colorado, Denver
Karsh Family Research Fund

Active, not recruiting

Tissue and Hematopoietic/Mesenchymal Stem Cell for Humanized Xenograft Studies in Melanoma and Squamous Head and Neck Cancer

Head and Neck Cancer | Malignant Melanoma

United States
Clinique Ovo

Terminated

Gcsf Injection in Women With Repeated Implantaiton Failure

Repeated Embryo Implantation Failure

Canada
Almirall, S.A.

Completed

Study of Pidotimod in Children With Recurrent Respiratory Tract Infections (RRI) (P-CRESCENT)

Recurrent Respiratory Tract Infections

China
Teva Branded Pharmaceutical Products R&D, Inc.

Withdrawn

Pharmacodynamics, Pharmacokinetics, Efficacy and Safety of Balugrastim in Pediatric Patients With Solid Tumors

Solid Tumors
Amgen

Completed

A Study of Peripheral Blood Progenitor Cell (PBPC) Mobilisation by Chemotherapy With Pegfilgrastim or Filgrastim in Subjects With Non-Hodgkin's Lymphoma

Non-Hodgkin's Lymphoma
University Hospital Tuebingen

Available

Personalized Multi-peptide Vaccination in Combination With the TLR1/2 Ligand XS15 in Cancer Patients (InHeVac01)

Cancer
Harvard Medical School (HMS and HSDM)
Chang-Hua Hospital

Withdrawn

Prevention of Acute Respiratory Infection in Taiwanese Institutionalized Elderly

Acute Respiratory Infection
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

A Study to Evaluate 5 μg/kg Tbo-filgrastim in Infants, Children and Adolescents With Solid Tumors Without Bone Marrow Involvement

Neutropenia

United States, Bulgaria, Croatia, Hungary, Poland, Romania, Russian Federation, Ukraine
DERSHENG SUN

Unknown

Efficacy of Granulocyte-Colony Stimulating Factor (G-CSF)

Neutropenia

Korea, Republic of
Tianjin SinoBiotech Ltd.

Completed

Fusion Protein rHSA/GCSFclinical Study on Breast Cancer Patients

Cancer, Breast | Chemotherapy-induced Neutropenia

China
Rabin Medical Center

Terminated

SubCutaneous (SC) Versus Intravenous (IV) Granulocyte Colony Stimulating Factors (G-CSF) for the Treatment of Neutropenia in Hospitalized Haemato-oncological Patients (G-CSF)

Leukemia

Israel
Sandoz

Completed

Phase III Study Comparing the Efficacy and Safety of EP2006 and Filgrastim (PIONEER)

Breast Cancer | Chemotherapy Associated Neutropenia

Czech Republic, Hungary, Latvia, Russian Federation, Slovakia, Ukraine
Clinical Institute of the Brain, Russia
City Hospital No 40, Saint Petersburg, Russia; Institute of Medical Cells Technologies

Completed

Granulocyte-colony Stimulating Factor for Stem Cells Therapy for Acute Ischemic Stroke (STEMTHER)

Ischemic Stroke

Russian Federation
National Cancer Institute (NCI)

Completed

Phase I Study of Intrathecal Mafosfamide

Lymphoma | Leukemia | Meningeal Neoplasm

United States
Amgen

Completed

Pegfilgrastim as Support to Pediatric Sarcoma Patients Receiving Chemotherapy

Sarcoma | Neutropenia
Genocea Biosciences, Inc.

Completed

Safety, Tolerability, and Efficacy Study of Prophylactic S. Pneumoniae Vaccine Following Challenge With S. Pneumoniae

Pneumococcal Infections | Pneumonia, Pneumococcal

United Kingdom
Clover Biopharmaceuticals AUS Pty Ltd
International Vaccine Institute; Coalition for Epidemic Preparedness Innovations

Completed

A Controlled Phase 2/3 Study of Adjuvanted Recombinant SARS-CoV-2 Trimeric S-protein Vaccine (SCB-2019) for the Prevention of COVID-19 (SCB-2019)

COVID-19

Colombia, Belgium, Brazil, Philippines, South Africa

3

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