Search clinical trials for: Adrenergic alpha-Agonists

Total 19210 results

The First Hospital of Qinhuangdao

Recruiting

Effect of Different Doses of Dexmedetomidine on Cerebral Oxygen Saturation and Postoperative Anxiety in Elderly Patients

Anxiety

China
Chinese PLA General Hospital
Beijing Tiantan Hospital

Recruiting

Effect of Intraoperative Dexmedetomidine on Postoperative Delirium in Elderly Patients Undergoing Major Abdominal Surgery

Delirium in Old Age

China
Maimonides Medical Center

Recruiting

Using Dexmedetomidine Prior to Intubation in Neonates

Effect Neonatal

United States
Beijing Tiantan Hospital

Recruiting

Effect of Dexmedetomidine on Postoperative Delirium After Awake Craniotomies

Delirium | Dexmedetomidine | Awake Craniotomy

China
Hong Kong Children's Hospital

Recruiting

Determining the Pharmacogenetic Basis of Non-responsiveness to the Sedative Effects of Dexmedetomidine in Children

Dexmedetomidine | Procedural Anxiety | Pharmacogenetic Study

Hong Kong
National Taiwan University Hospital

Recruiting

The Effect of Intraoperative Dexmedetomidine on Postoperative Morphine Requirements After Breast Cancer Surgery

Morphine Consumption

Taiwan
Mayo Clinic
National Heart, Lung, and Blood Institute (NHLBI); University of Minnesota

Active, not recruiting

Self-management of Sedative Therapy by Ventilated Patients

Critical Illness | Respiratory Failure | Anxiety

United States
Sollis Therapeutics, Inc.

Terminated

Sciatica Epidural Radiculopathy Experimental New Interventional TherapY Clonidine Micropellet (SERENITY CM)

Lumbosacral Radiculopathy

United States
Mylan Pharmaceuticals Inc

Completed

Food Study of Midodrine HCl Tablets 5 mg and ProAmatine® Tablets 5 mg

Healthy

United States
Children's Hospital of Philadelphia

Terminated

Pharmacokinetic Study of Intranasal Dexmedetomidine in Pediatric Patients With Congenital Heart Disease

Congenital Heart Disease | Dexmedetomidine

United States
Memorial Sloan Kettering Cancer Center

Completed

Placebo Controlled Clinical Trial of the Postoperative Opioid Sparing Effects of Intraoperative Dexmedetomidine Infusion for Thoracic Surgery

Pain

United States
Sindh Institute of Urology and Transplantation

Completed

Dexmedetomidine Versus Ketofol for Moderate Sedation in Endoscopic Retrograde Cholangiopancreatography

Sedation

Pakistan
Pierre-Yves P Lequeux

Completed

Opioid-sparing Effect of Intranasal Dexmedetomidine

Tonsillar Hypertrophy

United Arab Emirates
Seoul National University Hospital

Completed

Comparison of Remimazolam and Dexmedetomidine for Intraoperative Sedation

Orthopedic Disorder

Korea, Republic of
Turku University Hospital

Completed

Bioavailability of Intranasal Dexmedetomidine (INDEX)

Pharmacokinetics | Anesthesia | Arthritis Knee | Arthritis of Hip

Finland
Beijing Tiantan Hospital

Completed

Dexmedetomidine Alleviates Postoperative Delirium After Brain Tumor Resections

Postoperative Delirium | Dexmedetomidine

China
First Affiliated Hospital of Zhejiang University

Completed

Safety Study of Dexmedetomidine in Septic Patients

Sepsis | Agitation

China
Mayo Clinic
USWM, LLC (dba US WorldMeds)

Completed

Lofexidine for Adults Undergoing Lumbar Spine Surgery

Opioid Withdrawal

United States
Yangzhou University

Completed

Effects of Dexmedetomidine on Cardiac Electrophysiology in Patients Under General Anesthesia During Perioperative Period

General Anesthesia | Dexmedetomidine | Cardiac Function | Cardiac Electrophysiology

China
The Cleveland Clinic
Hospira, now a wholly owned subsidiary of Pfizer

Completed

Ancillary Effects of Dexmedetomidine Sedation After Cardiac Surgery (Decade)

Heart Disease

United States
Hospital for Special Surgery, New York

Terminated

The Effects of Dexmedetomidine Dose on Motor Evoked Potentials

Spinal Fusion

United States
National Institute on Drug Abuse (NIDA)

Completed

Clonidine for Relapse Prevention in Buprenorphine-Maintenance Patients

Opioid-Related Disorders

United States
Nanjing First Hospital, Nanjing Medical University

Unknown

The Mechanism of Dexmedetomidine in Improving Delirium After Cardiac Surgery

Delirium | Cardiac Surgery | Dexmedetomidine

China
Second Affiliated Hospital of Wenzhou Medical University

Unknown

Acceptable Hemodynamic Changes in Dexmedetomidine for Single Intravenous Bolus Injection

Mental Disorders | Pathologic Processes | Postoperative Complications | Delirium | Neurocognitive Disorders | Dexmedetomidine | Molecular Mechanisms of Pharmacological Action | Physiological Effects of Drugs | Analgesics | Hypnotics and Sedatives

China
Moscow Regional Research and Clinical Institute...

Completed

Effect of Perioperative Dexmedetomidine Administration on Outcome in Cardiac Surgery Patients

Patient Outcome Assessment

Russian Federation
Kyungmi Kim

Unknown

The Effect of Dexmedetomidine on Postoperative Quality of Recovery

The Effect of Dexmedetomidine on Postoperative Quality of Recovery

Korea, Republic of
Yonsei University

Completed

Effect of Dexmedetomidine on Postoperative Cognitive Function in Patients Undergoing Shoulder Arthroscopy With Beach Chair Position Under Desflurane Anesthesia

Rotator Cuff Tear

Korea, Republic of
The First Affiliated Hospital of Anhui Medical...

Completed

Impact of Dexmedetomidine on the Post-Operative Cognition Dysfunction(POCD) in Geriatric Patients

Delirium | Postoperative Confusion

China
Zhongda Hospital

Unknown

Dexmedetomidine for Prevention of Chronic Postoperative Pain

Chronic Postoperative Pain

China
USWM, LLC (dba US WorldMeds)
National Institute on Drug Abuse (NIDA)

Completed

Single-dose Pharmacokinetics and Safety of Oral Lofexidine in Renally-Impaired Subjects

Renally Impaired Subjects

United States
Sisli Hamidiye Etfal Training and Research Hospital

Completed

Dexmedetomidine in Children for Magnetic Resonance Imaging (MRI) Sedation (DEX)

Anesthesia
Yangzhou University

Unknown

Effects of Different Doses of Dexmedetomidine on Fentanyl-induced Cough

Fentanyl-induced Cough

China
Hospira, now a wholly owned subsidiary of Pfizer

Withdrawn

A Research Study to Evaluate the Effectiveness of Dexmedetomidine in Preventing Delirium After Heart Surgery

Delirium

United States
Mansoura University

Unknown

Optimal Single Dose Intrathecal Dexmedetomidine for Postoperative Analgesia

Lower Limb Surgery

Egypt
South Egypt Cancer Institute

Unknown

Efficacy and Safety of Dexmedetomidine Added to Modified Pectoral's Block in Breast Cancer Patients

Breast Cancer Patients

Egypt
Arcion Therapeutics Inc

Completed

Efficacy and Safety Study of ARC-4558 for Management of Pain Associated With Painful Diabetic Neuropathy

Painful Diabetic Neuropathy

United States
Joseph D. Tobias

Completed

Bradycardia Following Intraoperative Administration of Dexmedetomidine

Adenotonsillectomy | Tonsillectomy

United States
Guangzhou Women and Children's Medical Center

Completed

The Effect of Age on the Median Effective Dose (ED50) of Intranasal Dexmedetomidine for Rescue Sedation Following Failed Sedation With Oral Chloral Hydrate During Magnetic Resonance Imaging

Aged | Drug | Dose-Response Relationship

China
Hospira, now a wholly owned subsidiary of Pfizer

Terminated

A Research Study to Evaluate the Effectiveness of Dexmedetomidine in Preventing Delirium After Hip Fracture Repair Surgery

Delirium

United States
Children's National Research Institute

Completed

The Pharmacology and Hemodynamics of Dexmedetomidine in Children With Congenital Heart Disease

Atrial Septal Defect | Cardiac Transplant | Patent Ductus Arterious | Bidirectional Cavopulmonary Anastomosis

United States
Yonsei University

Completed

Effects of a Dexmedetomidine on Quality of Recovery 40 and Postoperative Nausea and Vomiting in Breast Cancer Surgery

Breast Cancer

Korea, Republic of
Uppsala University Hospital

Completed

Effects of Dexmedetomidine During Radiofrequency Ablation of Abdominal Tumours

Cancer of Liver | Cancer of Kidney and Renal Pelvis

Sweden
University of California, San Francisco

Terminated

Use of Dexmedetomidine to Facilitate Extubation in Surgical ICU Patients Who Failed Previous Weaning Attempts

Respiration Disorders | Intubation; Difficult

United States
Concordia Pharmaceuticals Inc., Barbados

Completed

Efficacy & Safety of KAPVAY™ Extended-Release in Children & Adolescents With Attention Deficit Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder
TC Erciyes University

Completed

Efficacy of Peritonsillar Dexmedetomidine Infiltration for Postadenotonsillectomy Pain

Pain Postoperative, Intraoperative Hemorrhage
Huazhong University of Science and Technology

Unknown

Dexmedetomidine on Postoperative Delirium and Quality of Recovery in Geriatric Patients

Delirium, Postoperative

China
Allergan

Completed

Safety and Efficacy of Brimonidine Tartrate Posterior Segment Drug Delivery System in Improving Visual Function

Rhegmatogenous Macula-off Retinal Detachment

United Kingdom, Korea, Republic of, Israel, India, United States, Philippines
Athena Zuppa

Completed

Understanding Dexmedetomidine in Neonates After Open Heart Surgery (Dex)

Hypoplastic Left Heart | Tetrology of Fallot | Heart Ventricle

United States
Chiang Mai University

Completed

The Effect of Dexmedetomidine on Hemodynamic Response During Double Lumen Endotracheal Intubation

Hypertension | Tachycardia | Intubation Complication | Anesthesia Intubation Complication | Tracheal Intubation Morbidity | High Blood Pressure

Thailand
Stanford University

Not yet recruiting

Stanford and University of Illinois Chicago ACE-D Study (ACE-D)

Depression

United States

Search clinical trials for: Adrenergic alpha-Agonists

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Canada

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations