Search clinical trials for: Adrenergic beta-2 Receptor Agonists

Total 9981 results

Aaron Cypess
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Completed

Effects of b3-Adrenergic Receptor Agonists on Brown Adipose Tissue

Obesity

United States
Henning Bundgaard

Completed

Beta 3 Agonist Treatment in Heart Failure (Beat-HF)

Chronic Heart Failure With Reduced Ejection Fraction (HFrEF)

Australia, Denmark
AstraZeneca

Completed

Multiple Ascending Doses (MAD) of AZD3199 Given Once Daily as Inhaled Formulation Via Turbuhaler to Healthy Men (AZD3199MAD)

Healthy Volunteers

Sweden
AstraZeneca

Completed

Evaluation of the Pharmacokinetics and the Pharmacodynamics of Different Dry Powder Inhalation Formulations of AZD3199 in Patients With Asthma

Asthma

Sweden
Yonsei University

Active, not recruiting

Effect of Mirabegron on Bladder Compliance

Patients With Low Bladder Compliance of 20ml/H2O or Less Despite Taking Anticholinergics

Korea, Republic of
Velicept Therapeutics, Inc.

Completed

Evaluate the Safety, Tolerability and PK of Different Formulations of Orally Administered Solabegron in Healthy Male Subjects

Healthy Subjects, Overactive Bladder
Boryung Pharmaceutical Co., Ltd

Completed

A Study to Evaluate Drug-drug Interactions Between BR9006-1 and BR9006-2 in Healthy Male Volunteers.

Overactive Bladder | Benign Prostatic Hyperplasia (BPH)

Korea, Republic of
University Hospital, Basel, Switzerland

Completed

Beta 2 Adrenergic Stimulation vs Cold Exposure to Activate Human Brown Adipose Tissue (ASCENT)

Thermogenesis

Switzerland
AstraZeneca

Completed

Assess Safety, Tolerability and PK of AZD3199 in Japanese

Healthy

United Kingdom
Novartis

Completed

Omalizumab Use and Asthma-Related Quality of Life in Patients With Severe Persistent Allergic Asthma

Asthma

Brazil
Novartis

Completed

Study to Demonstrate Equivalence of Formoterol 12 and 24 µg Delivered Via Two Types of Single Dose Dry Powder Inhalers (Concept1 and Aerolizer)

Asthma

Germany
Forest Laboratories

Completed

Study of the Efficacy and Safety of the Combination of Two FDA Approved Oral Medications, Nebivolol and Valsartan for Treatment of Stage 1 or 2 Hypertension

Stage 2 Hypertension | Stage 1 Hypertension

United States
GlaxoSmithKline

Completed

A Two-Part Study to Determine: Best Medication Formulation and Food Effect

Overactive Bladder

United States
GlaxoSmithKline

Completed

Dose Ranging Study Of Solabegron Versus Placebo In Female Patients With Overactive Bladder Symptoms

Overactive Bladder

Germany, Taiwan, Netherlands, Spain, Australia, Korea, Republic of, Latvia, Argentina, Slovenia, Finland, France, South Africa, Poland, New Zealand
James Martins
National Center for Research Resources (NCRR)

Withdrawn

Clonidine to Prevent Implantable Cardiovertor Defibrillator Firing

Ventricular Tachycardia

United States
GlaxoSmithKline

Completed

A Study To Investigate GW427353 In Subjects With Irritable Bowel Syndrome (IBS)

Irritable Bowel Syndrome (IBS)

Germany, Australia, France
Clinical Hospital Center Zemun

Withdrawn

Echocardiographic Study of a Single Dose Bisoprolol Versus Nebivolol in Healthy Subjects (BINEB)

Bisoprolol Adverse Reaction | Nebivolol Adverse Reaction

Serbia
University of Minnesota
Forest Laboratories

Completed

A Study Examining the Effects of Nebivolol Compared to Atenolol on Endothelial Function (EVIDENCE)

Hypertension

United States
Mayo Clinic

Completed

Dose Response and Receptor Selectivity of Beta-blocker Effects on Bone Metabolism

Osteoporosis, Age-Related

United States
University of Chicago
Forest Laboratories

Completed

Safety Study to Lower the Risk of Heart Failure is Also Effective in Reducing Stiffness of the Arteries (EFFORT)

Hypertension | Diabetes

United States
Forest Laboratories

Unknown

Economic Impact of Switching From Metoprolol to Nebivolol for Hypertension Treatment

Hypertension

United States
Vanderbilt University

Completed

Comparative Effect of Nebivolol vs. Metoprolol on Insulin Sensitivity and Fibrinolytic Balance in Metabolic Syndrome

Metabolic Syndrome

United States
Creighton University

Withdrawn

Impact of Nebivolol on Central Aortic Pressure

Central Aortic Pressure

United States
Université de Sherbrooke
Laval University

Completed

Activation of Brown Adipose Tissue Metabolism Using Mirabegron (GB9)

Type 2 Diabetes

Canada
Forest Laboratories
Mylan Laboratories

Terminated

Study to Evaluate Symptoms in Patients Treated With Nebivolol or Metoprolol Extended-release (ER) for Hypertension

Hypertension

United States
Mylan Bertek Pharmaceuticals

Completed

Safety and Efficacy of Nebivolol in the Treatment of Hypertension in African Americans

Hypertension

United States
Parc de Salut Mar

Completed

Generation of Biological Samples Positive to Salmeterol for Anti-Doping Control (SALM)

Healthy Volunteers

Spain
University of Copenhagen

Completed

Pharmacological Properties of Salmeterol

Pharmacokinetics in Healthy Young Men

Denmark
Novartis Pharmaceuticals
Pacira Pharmaceuticals, Inc

Completed

Formoterol Certihaler, Tiotropium HandiHaler and Tiotropium HandiHaler in Combination With Formoterol Certihaler in Patients With Stable Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

Switzerland
Dey

Completed

Study in Patients With Asthma

Asthma

United States
Dey

Completed

Study in Patients With COPD

COPD

United States
Dey

Completed

Study in Patients With Asthma

Asthma

United States
Dey

Completed

Study in Patients With COPD

Chronic Obstructive Pulmonary Disease | COPD

United States
Novartis
Pacira Pharmaceuticals, Inc

Completed

A 3-week Study Investigating Patient Use and Functionality of Formoterol in a Novel Inhalation Device in Patients With Asthma

Asthma

United States
Dey

Completed

Study in Patients With Asthma

Asthma

United States
Johannes Gutenberg University Mainz
AstraZeneca

Completed

Change of Inspiratory Peak Flow in COPD

Chronic Obstructive Pulmonary Disease

Germany
Zhejiang Provincial People's Hospital

Recruiting

Effect of Mirabegron on Promoting Brown Adipose Tissue Activation

Tumour

China
Astellas Pharma Inc
Astellas Pharma Singapore Pte. Ltd.

Completed

A Phase 4 Study to Evaluate the Efficacy, Safety, and Tolerability of Mirabegron in Male Subjects With Overactive Bladder (OAB) Symptoms, While Taking the Alpha Blocker for Benign Prostatic Hypertrophy (BPH)

Overactive Bladder

Japan, Korea, Republic of
Peking Union Medical College Hospital

Not yet recruiting

Mirabegron Combined With Behavioral Intervention for Overactive Bladder：a Prospective Multicenter Randomized Controlled Clinical Study

Overactive Bladder
CHU de Quebec-Universite Laval

Completed

Add-on Mirabegron in Pediatric Patients With Refractory Overactive Bladder (Add-on-Mira)

Overactive Bladder | Urinary Incontinence
Southern Illinois University
Astellas Scientific & Medical Affairs, Inc.; Sisters of the Third Order of...

Completed

Myrbetriq™ (Mirabegron) to Improve Disordered Sleep in Subjects With Lower Urinary Tract Symptoms (LUTS)

Lower Urinary Tract Symptoms | Nocturia

United States
Hospital Kemaman

Completed

Acute Tocolysis With Terbutaline for Suspected Fetal Distress

Nonreassuring Fetal Status

Malaysia
Imperial College London
Foundation for Circulatory Health

Completed

The Effect of Nebivolol on Insulin Sensitivity

Hypertension

United Kingdom
University of Miami
Forest Laboratories

Completed

Nebivolol Versus Metoprolol: Sodium Sensitivity

Hypertension

United States
Emory University
Georgia Institute of Technology

Completed

Evaluation of The Effects of Nebivolol in Comparison to Atenolol on Wall Shear Stress and Rupture Prone Coronary Plaques

Atherosclerosis | Endothelial Function

United States
Astellas Pharma Inc

Completed

To Compare Blood and Urine Concentrations of Mirabegron (YM178) in Healthy Poor or Extensive Metabolizers for CYP2D6 and to Assess the Effect of Mirabegron on the Metabolism of Metoprolol

Healthy Subjects | Pharmacokinetics of Mirabegron

Netherlands
GlaxoSmithKline

Completed

Effects of Salmeterol on Autonomic Nervous System (ESAN)

Pulmonary Disease, Chronic Obstructive

Germany
Catholic University, Italy

Completed

Polymorphism of beta2-adrenoceptor and Regular Use of Formoterol in Asthma

Asthma

Italy
Dey

Completed

Study in Patients With COPD

COPD

United States
Dey

Completed

Study in Patients With Asthma

Asthma

United States

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