Search clinical trials for: Aerosolized All trans retinoic acid plus Vitamin D

Total 768 results

Kafrelsheikh University
Ministry of Health, Saudi Arabia; Foshan University Laboratory of Emerging... and other collaborators

Not yet recruiting

Investigating the Potential Role of Aerosolized Retinoic Acid, a Potent Vitamin A Metabolite for Treating COVID-19 Anosmia and Retinoic Acid Insufficiency .A Novel Approach for Regaining Sense of Smell.

Post COVID-19 Anosmia (Loss of Smell)

China, Egypt, Saudi Arabia
Kafrelsheikh University
Damietta University

Unknown

Aerosol Combination Therapy of All-trans Retinoic Acid and Isotretinoin as A Novel Treatment for Inducing Neutralizing Antibodies in COVID -19 Infected Patients Better Than Vaccine : An Innovative Treatment (Antibodies)

COVID-19
Shandong University

Withdrawn

All-Trans Retinoic Acid (ATRA) Combining Dexamethasone Versus High-dose Dexamethasone for Initial Treatment of Primary Immune Thrombocytopenia (ITP)

Purpura | Idiopathic Thrombocytopenic Purpura

China
Dwight Owen

Recruiting

All-Trans Retinoic Acid (ATRA) and Atezolizumab for the Treatment of Recurrent or Metastatic Non-Small Cell Lung Cancer

Metastatic Lung Non-Small Cell Carcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Recurrent Lung Non-Small Cell Carcinoma

United States
Kafrelsheikh University
1-Foshan University Laboratory of Emerging Infectious Disease Institute of... and other collaborators

Not yet recruiting

Assessment the Activity Value of Isotretinoin (13- Cis-Retinoic Acid ) in the Treatment of COVID-19 ( Isotretinoin in Treatment of COVID-19) (Randomized) (Isotretinoin)

COVID19

Egypt
Kafrelsheikh University
Ministry of Health, Saudi Arabia

Not yet recruiting

Utilizing the Crosstalk Among Chicoric Acid, 13-Cis Retinoic Acid(Aerosolized), Minocycline and Vitamin D as a Potent Quadrate Therapy for Treating Patients With Multidrug-resistant TB and Patient With Both Multidrug-resistant TB and COVID-19

Tuberculosis

Egypt, Saudi Arabia
Peking University People's Hospital
Beijing Friendship Hospital; Beijing Tongren Hospital; Beijing Hospital; Navy General...

Not yet recruiting

The Combination of ATRA and Eltrombopag as the Treatment of Steroid-resistant/Relapse ITP Based on MSC-C5b-9

Purpura, Thrombocytopenic, Idiopathic

China
Yale University
Mayo Clinic

Completed

Combination Therapy With Ursodeoxycholic Acid (UDCA) and All-Trans Retinoic Acid (ATRA) for Treatment of Primary Sclerosing Cholangitis

Cholangitis, Sclerosing

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Tretinoin and Arsenic Trioxide With or Without Gemtuzumab Ozogamicin in Treating Patients With Previously Untreated Acute Promyelocytic Leukemia

Acute Promyelocytic Leukemia With PML-RARA

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Feasibility of Retinoic Acid Treatment in Emphysema (FORTE)

Lung Diseases | Lung Diseases, Obstructive | Chronic Obstructive Pulmonary Disease | Emphysema
Yale University

Terminated

An Efficacy Trial of Low Dose All-trans Retinoic Acid in Patients With Primary Sclerosing Cholangitis

Cholangitis, Sclerosing

United States
Gruppo Italiano Malattie EMatologiche dell'Adulto

Unknown

AIDA 2000 Guidelines

Acute Promyelocytic Leukemia

Italy
Gruppo Italiano Malattie EMatologiche dell'Adulto

Unknown

"AIDA" Protocol (LAP 0493)

Leukemia

Italy, Belgium, Germany, Netherlands, Turkey
Kafrelsheikh University

Not yet recruiting

Combination of Recombinant Bacterial ACE2 Receptors -Like Enzyme of B38-CAP and Isotretinoin Could be Promising Treatment for COVID-19 Infection- and Its Inflammatory Complications

COVID
Amsterdam UMC, location VUmc
UMC Utrecht; Erasmus Medical Center; University of Turin, Italy; Vejle Hospital

Completed

Daratumumab in Combination With ATRA (DARA/ATRA)

Multiple Myeloma

Netherlands
Peking University People's Hospital
Qilu Hospital of Shandong University; Beijing Hospital; Navy General Hospital...

Unknown

A Study of ATRA in the Treatment of ITP

Immune Thrombocytopenia

China
Stephen Bagley, MD, MSCE
University of Pennsylvania; Incyte Corporation

Recruiting

All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma

Glioma | Astrocytoma | Oligodendroglioma | IDH Mutation

United States
First Affiliated Hospital of Suzhou Medical College

Completed

Efficacy of Immunomudulatory Therapy With All-trans Retinoid Acid for Adults With Chronic Immune Thrombocytopenia (ITP)

Immune Thrombocytopenic Purpura

China
Peking University People's Hospital
Ministry of Science and Technology of the People´s Republic of China

Not yet recruiting

Randomized,International Multi-center Clinical Trial of RIF Plus RA for Non-high-risk APL (RIF)

Acute Promyelocytic Leukaemia
Peking University People's Hospital
Qilu Hospital of Shandong University; Beijing Tongren Hospital; Beijing Municipal... and other collaborators

Completed

The Combination of ATRA and Danazol as Second-line Treatment in Adult Immune Thrombocytopenia

Autoimmune Thrombocytopenia

China
Shanghai Ninth People's Hospital Affiliated to...

Recruiting

All-trans Retinoic Acid (ATRA) in the Treatment of Recurrent/Metastatic Adenoid Cystic Carcinoma of the Head and Neck (Aplus)

Adenoid Cystic Carcinoma of the Head and Neck

China
Imago BioSciences, Inc., a subsidiary of Merck...

Completed

A Study of Bomedemstat (IMG-7289/MK-3543) With and Without ATRA, in Participants With Advanced Myeloid Malignancies (IMG-7289-CTP-101/MK-3543-001)

Acute Myeloid Leukemia | Myelodysplastic Syndrome

Australia
Kafrelsheikh University

Unknown

Efficacy and Safety of Drug Combination Therapy of Isotretinoin and Some Antifungal Drugs as A Potential Aerosol Therapy for COVID-19 : An Innovative Therapeutic Approach COVID-19 (Isotretinoin)

Covid19

Egypt
Kafrelsheikh University

Not yet recruiting

Investigating the Role of 13cis Retinoic Acid in the Treatment of COVID-19 and Enhancement of Its Spike Protein Based Vaccine Efficacy and Safety. (Isotretinoin)

Covid19 Vaccine
Kafrelsheikh University

Unknown

Combination of Chemopreventive Agents (All- Trans Retinoic Acid and Tamoxifen) as Potential Treatment for the Lung Complication of COVID-19

the Lung Complication of COVID-19
Hospital Universitario Dr. Jose E. Gonzalez

Recruiting

Effectiveness and Safety of Therapy Based on Attenuated ATO Plus Low-Dose ATRA in Patients With APL

Promyelocytic Leukemia

Mexico
H. Lee Moffitt Cancer Center and Research Institute
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Vaccine Therapy, Tretinoin, and Cyclophosphamide in Treating Patients With Metastatic Lung Cancer

Lung Cancer

United States
Kafrelsheikh University

Unknown

Clinical Role of Testosterone and Dihydrotestosterone and Which of Them Should be Inhibited in COVID-19 Patients - A Double-edged Sword?

Covid19
First Affiliated Hospital Xi'an Jiaotong University

Recruiting

Treatment of Acute Myeloid Leukemia With Arsenic and All-trans Retinoid Acid

Acute Myeloid Leukemia

China
Dana-Farber Cancer Institute
Brigham and Women's Hospital

Completed

A Study of All-Trans Retinoic Acid (ATRA) and Bryostatin in Patients With Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndrome | Acute Myelogenous Leukemia

United States
The First Affiliated Hospital of Xiamen University

Recruiting

All-trans Retinoic Acid in Combination With a KPD Regimen for the Treatment of Refractory/Relapsed Multiple Myeloma

Multiple Myeloma in Relapse | Multiple Myeloma, Refractory

China
Peking University People's Hospital
Beijing Tongren Hospital; Beijing Hospital; Navy General Hospital, Beijing

Unknown

The Combination of Low-dose Rituximab and ATRA as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia

Immune Thrombocytopenia

China
The First Affiliated Hospital of Soochow University

Recruiting

Aza With or Without ATRA in Newly Diagnosed Unfit AML or Intermediate,High or Very High Risk MDS

AML | MDS | Old Age; Debility | Hematologic Cancer

China
Memorial Sloan Kettering Cancer Center

Terminated

3F8/GM-CSF Immunotherapy Plus 13-Cis-Retinoic Acid for Consolidation of Second or Greater Remission of High-Risk Neuroblastoma

Neuroblastoma

United States
National Cancer Institute (NCI)

Completed

A Pilot Study of the Combination of Retinoic Acid and Interferon-Alpha2a for the Treatment of Lymphoproliferative Disorders in Children With Immunodeficiency Syndromes

HIV Infections | Immunologic Deficiency Syndromes | Lymphoproliferative Disorders

United States
Kafrelsheikh University

Unknown

Efficacy of Aerosol Combination Therapy of 13 Cis Retinoic Acid and Captopril for Treating Covid-19 Patients Via Indirect Inhibition of Transmembrane Protease, Serine 2 (TMPRSS2)

Covid19
University of Pittsburgh

Completed

Study of Dasatinib and All-Trans Retinoic Acid for Relapsed/Refractory and/or Elderly Patients With Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome

Myelodysplastic Syndrome | Acute Myelogenous Leukemia

United States
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Tretinoin and Arsenic Trioxide in Treating Patients With Untreated Acute Promyelocytic Leukemia

Acute Promyelocytic Leukemia With t(15;17)(q24.1;q21.2); PML-RARA

United States, Canada, Saudi Arabia, Puerto Rico, Australia, New Zealand
Eunice Kennedy Shriver National Institute of Child...
Centers for Disease Control and Prevention

Completed

Healthy Infant Development Project

Iron Deficiency Anemia | Iron Deficiency

China
University of Colorado, Denver
Merck Sharp & Dohme LLC

Active, not recruiting

Pembrolizumab and All-Trans Retinoic Acid Combination Treatment of Advanced Melanoma

Stage IV Melanoma | Advanced Melanoma | Stage III Melanoma

United States
Gruppo Italiano Malattie EMatologiche dell'Adulto
Study Alliance Leukemia (SAL) Group

Completed

Phase III Trial in Acute Promyelocytic Leukemia Patients (APL0406)

Leukemia

Germany, Italy, Austria
China Medical University Hospital

Recruiting

Nivolumab and All-trans Retinoic Acid for Pancreatic Cancer

Effect of Drug

Taiwan
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Promyelocytic Leukemia

Myeloid Neoplasm | Childhood Acute Promyelocytic Leukemia With PML-RARA

United States, Canada, Puerto Rico
Incyte Corporation

Terminated

An Open-Label, Dose-Escalation/Dose-Expansion Safety Study of INCB059872 in Subjects With Advanced Malignancies

Solid Tumors and Hematologic Malignancy

United States, Netherlands, Belgium
Huiqing Sun
Zhengzhou University

Completed

Effects of Early Vitamin A Supplementation on the Risk for Retinopathy of Prematurity in Extremely Preterm Infants

Retinopathy of Prematurity

China
H. Lee Moffitt Cancer Center and Research Institute

Completed

To Immunize Patients With Extensive Stage SCLC Combined With Chemo With or Without All Trans Retinoic Acid

Small Cell Lung Cancer

United States
Mirati Therapeutics Inc.

Completed

A Phase II Study of MGCD0103 (MG-0103) in Patients With Refractory Chronic Lymphocytic Leukemia

Lymphocytic Leukemia, Chronic

United States, Canada
Bambino Gesù Hospital and Research Institute

Completed

DHA and Vitamin D in Children With Biopsy-proven NAFLD (VitD_DHA)

NAFLD | Non Alcoholic Steatohepatitis (NASH)

Italy
Associazione Italiana Ematologia Oncologia Pediatrica

Recruiting

Treatment Study for Children and Adolescents With Acute Promyelocytic Leukemia

Acute Promyelocytic Leukemia

Belgium, Netherlands, Czechia, Denmark, France, Germany, Ireland, Israel, Italy, Portugal, Spain, Sweden
Shinshu University

Recruiting

Changes of Bone Turnover Markers and Bone Mineral Density After Osteoporosis Treatment

Osteoporosis

Japan

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