Search clinical trials for: Aflibercept 2mg

Total 9776 results

Kyowa Kirin, Inc.

Recruiting

Study to Assess the Efficacy & Safety of KHK4951 in Patients With Diabetic Macular Edema

Diabetic Macular Edema (DME)

Australia, United States, Japan, Korea, Republic of
Novartis Pharmaceuticals

Completed

A Non-interventional Study to Assess the Influence of Automated Optical Coherence Tomography Image Enrichment With Segmentation Information on Disease Activity Assessment in Patients Treated With Licensed Anti- VEGF Injections (RAZORBILL)

Neovascular Age-Related Macular Degeneration

Spain, Italy, Germany, Canada, Ireland
McMaster University

Active, not recruiting

Mean Visual Acuity Changes Following Five Injections of Aflibercept

Diabetic Macular Edema

Canada
Al Hadi Hospital

Completed

IVI Aflibercept Before and After Phaco in DME.

Diabetic Macular Edema

Kuwait
Siriraj Hospital

Completed

Aflibercept as Adjunctive Treatment for Filtration Surgery in Neovascular Glaucoma

Intraocular Pressure | Neovascular Glaucoma | Vascular Endothelial Growth Factor Overexpression | Glaucoma Secondary to Eye Inflammation

Thailand
Spanish Cooperative Group for the Treatment of...
Sanofi

Completed

Phase II Trial to Assess FOLFIRI+Aflibercept Efficacy in Patients With Oxaliplatin-pretreated Metastatic Colorectal Cancer With or Without ACE Polymorphisms (POLAF)

Metastatic Colorectal Cancer

Spain
Bayer
Regeneron Pharmaceuticals

Completed

Real Life of Aflibercept in France in Patients Refractory to Ranibizumab: Observational Study in Wet AMD (TITAN)

Wet Macular Degeneration

France
Pusan National University Hospital
Bayer

Completed

Effect of Intravitreal VEGF-Trap Eye on Polypoidal Choroidal Vasculopathy (VAULT)

Polypoidal Choroidal Vasculopathy | Exudative Age-related Macular Degeneration

Korea, Republic of
Regeneron Pharmaceuticals

Not yet recruiting

An Observational Study to Investigate the Use of Aflibercept 8 mg to Treat Adult Patients With Neovascular Age-Related Macular Degeneration (nAMD) and Diabetic Macular Edema (DME) in a Real-World Setting (SPECTRUM-US)

Visual Impairment | Diabetic Macular Edema (DME) | Neovascular Age-related Macular Degeneration (nAMD) | Wet Age-related Macular Degeneration (AMD)
Innostellar Biotherapeutics Co.,Ltd

Recruiting

Safety and Efficacy of LX102 Gene Therapy in Patients With Neovascular Age-related Macular Degeneration (nAMD) (VENUS)

Neovascular Age-Related Macular Degeneration

China
Institut für Klinische Krebsforschung IKF GmbH...
Sanofi; Trium Analysis Online GmbH; STABIL - Statistische und Biometrische Lösungen

Completed

Aflibercept and 5-FU vs. FOLFOX as 1st Line Treatment for Elderly or Frail Elderly Patients With Met. Colorectal Cancer (ELDERLY)

Colorectal Cancer

Germany
University of Oklahoma

Completed

Aflibercept Injection for Proliferative Diabetic Retinopathy

Vitreous Hemorrhage

United States
Bayer

Completed

Aflibercept Injection Into the Vitreous Body of the Eye: Study to Learn More About Patient Relevant Outcomes, Real World Treatment Patterns and How Well the Treatment Works for Patients Suffering From Abnormal Growth of New Blood Vessels Under the Retina. (ANDROMEDA)

Macular Degeneration

Germany
Regeneron Pharmaceuticals

Completed

Study to Evaluate an Aflibercept (EYLEA®) Prefilled Syringe

Chorioretinal Vascular Disease

United States
Sanofi
Regeneron Pharmaceuticals

Completed

Aflibercept and Standard Chemotherapy (R-CHOP) in First Line of Non Hodgkin B-cell Lymphoma

Lymphoma, Non-Hodgkin

France
Zydus Therapeutics Inc.

Completed

Saroglitazar Magnesium in the Treatment of Non-Alcoholic Steatohepatitis (EVIDENCES VI)

Non Alcoholic Steatohepatitis

United States
Gannex Pharma Co., Ltd.

Recruiting

Study to Evaluate the Safety, Tolerability, and Efficacy of ASC41 Tablets in Adult Patients With NASH

Non-alcoholic Fatty Liver Disease | Non-alcoholic Steatohepatitis

China
Odense University Hospital
Zealand University Hospital; Queen's University, Belfast; Synoptik-Fonden; AP Moeller... and other collaborators

Completed

Navigated Laser In Branch Retinal Vein Occlusion Study (NIRVANA)

Macular Edema | Branch Retinal Vein Occlusion

Denmark
Bayer

Completed

Prospective Observational Study to Assess Effectiveness of Intravitreal Aflibercept in Patients With Wet Macular Degeneration in Greece (PERSEUS-GR)

Macular Degeneration | Choroidal Neovascularization

Greece
Bayer

Completed

Efficacy and Safety of Three Different Aflibercept Regimens in Subjects With Diabetic Macular Edema (DME) (VIOLET)

Macular Edema

Spain, Canada, Switzerland, Portugal, Austria, Poland, Slovakia, United Kingdom, Germany, Hungary, Italy, France, Lithuania, Czechia
Bayer
Regeneron Pharmaceuticals

Completed

Special Drug Use Investigation of EYLEA for Myopic Choroidal Neovascularization

Choroidal Neovascularization

Japan
Unity Health Toronto

Completed

Predictors of Treatment Response to Aflibercept and Aqueous Cytokine Levels in Diabetic Macular Edema

Diabetic Macular Edema

Canada
Bayer
Regeneron Pharmaceuticals

Completed

To Describe the Use of Intravitreal Aflibercept and to Describe Follow-up as Well as Treatment Patterns in Patients With Wet Age-related Macular Degeneration (wAMD) or Diabetic Macular Edema (DME) in Routine Clinical Practice in Canada. (PEGASUS)

Wet Macular Degeneration

Canada
Bayer
Regeneron Pharmaceuticals

Completed

EYLEA [AMD-QOL(Age-Related Macular Degeneration-Quality of Life)] Post-marketing Surveillance in Japan

Macular Degeneration

Japan
Bayer
Regeneron Pharmaceuticals

Completed

Investigating the Effectiveness of Eylea in Patients With Wet Age-related Macular Degeneration (PERSEUS)

Wet Age-related Macular Degeneration

Germany
University of Exeter
Beachbody

Completed

Vegan or Animal Protein Ingestion on the Recovery of Muscle Function Following Exercise (VAMPIRE)

Muscle Recovery

United Kingdom
DSM Nutritional Products, Inc.
Abbott Nutrition

Completed

Effects of Lutein on Learning and Memory in Chronically Stressed Subjects and in an Acute Stressful Situation (TSST - Trier Social Stress Test): A Randomized, Double-blind, Placebo-controlled Trial) (MemLearn)

Healthy But Chronically Stressed

Germany
4D Molecular Therapeutics

Recruiting

4D-150 in Patients With Diabetic Macular Edema

Diabetic Retinopathy | Diabetic Macular Edema

United States, Puerto Rico
Seoul National University Hospital

Completed

Visual Function Change in Wet Age-related Macular Degeneration Patients With Better Baseline Visual Acuity

Age-Related Macular Degeneration

Korea, Republic of
Bayer
Regeneron Pharmaceuticals

Completed

Routine Clinical Practice for Use of Intravitreal Aflibercept Treatment in Patients With Diabetic Macular Edema (APOLLON)

Diabetic Retinopathy

France
Bayer

Completed

A Study Reviewing Medical Records to Learn More About Treat-and-extend With Eylea in Patients With Neovascular Age-related Macular Degeneration (nAMD). (BELUGA)

Neovascular Age-related Macular Degeneration

Belgium
Bayer

Completed

A Study in Patients With Wet Age-related Macular Degeneration or Diabetic Macular Edema to Assess the freQuency of Use of Intravitreal Aflibercept in Routine Clinical Practices in Latin America (AQUILA)

Macular Degeneration

Mexico, Argentina, Colombia, Costa Rica
Bayer

Completed

Efficacy and Safety of Two Different Aflibercept Regimens in Subjects With Neovascular Age-related Macular Degeneration (nAMD)

Macular Degeneration

Spain, Switzerland, Portugal, France, Canada, United Kingdom, Austria, Slovakia, Germany, Hungary, Italy, Lithuania, Czechia, Poland
Bayer

Completed

An Integrated Analysis of the Effectiveness of Intravitreal (IVT) Aflibercept (Eylea) in Routine Clinical Practice Based on Two Large Observational Studies (GALAXY)

Macular Degeneration

Germany
Bayer
Regeneron Pharmaceuticals

Completed

Study for Collection of Aflibercept Data in Routine Practice (CODEX)

Eye Diseases

France
Bayer
Regeneron Pharmaceuticals

Completed

Prospective, Non-interventional, Multi-center Post-authorization Safety Study of Eylea for Central Retinal Vein Occlusion (CRVO) (JPMS-CRVO)

Retinal Vein Occlusion

Japan
Bayer
Regeneron Pharmaceuticals

Completed

Japanese Phase 3 Study of Aflibercept in Neovascular Glaucoma Patients (VEGA)

Glaucoma, Neovascular

Japan
Bayer
Regeneron Pharmaceuticals

Completed

Evaluation of Physician Knowledge of Safety and Safe Use Information for Aflibercept in Canada

Diabetic Macular Edema (DME) | Age-related Macular Degeneration (AMD) | Central Retinal Vein Occlusion (CRVO)

Canada
Jeffrey S Heier
Regeneron Pharmaceuticals

Unknown

IAI Versus Sham as Prophylaxis Against Conversion to Neovascular AMD (PRO-CON)

Age-Related Macular Degeneration

United States
GlaxoSmithKline

Completed

A Study of GSK256073 in Subjects With Type 2 Diabetes Mellitus Who Are Being Treated With Metformin

Diabetes Mellitus, Type 2

Spain, United Kingdom, United States, France
Jaeb Center for Health Research
National Eye Institute (NEI); National Institutes of Health (NIH); Regeneron...

Completed

Anti-VEGF vs. Prompt Vitrectomy for VH From PDR (AB)

Proliferative Diabetic Retinopathy | Vitreous Hemorrhage

United States, Canada
Bayer
Regeneron Pharmaceuticals

Completed

Aflibercept for Retinopathy of Prematurity - Intravitreal Injection Versus Laser Therapy (FIREFLEYE)

Retinopathy of Prematurity (ROP)

Spain, Singapore, Hong Kong, Korea, Republic of, Malaysia, Japan, Taiwan, Sweden, Portugal, Belgium, Argentina, Bulgaria, Italy, Austria, Brazil, Czechia, Greece, Hungary, Israel, Netherlands, Poland, Romania, Russian Federation, Slov... and more
Regeneron Pharmaceuticals

Terminated

Study of Intravitreal REGN2176-3 in Participants With Neovascular ("Wet") Age-Related Macular Degeneration (AMD) (CAPELLA)

Neovascular Age-Related Macular Degeneration

United States, Japan
Association for Innovation and Biomedical Research...
European Vision Institute Clinical Research Network

Completed

Randomized, Double-masked, Sham-controlled Phase 4 Study, Efficacy, Safety, and Tolerability of Intravitreal Aflibercept Monotherapy Compared to Aflibercept With Adjunctive Photodynamic Therapy in Patients With Polypoidal Choroidal Vasculopathy (ATLANTIC)

Polypoidal Choroidal Vasculopathy

Portugal, Spain
Changhua Christian Hospital

Completed

Real World Outcomes of Intravitreal Anti-vascular Endothelial Growth Factors for Neovascular Age Related Macular Degeneration in Taiwan (OIVAEGFFAMDIT)

AMD

Taiwan
Pfizer

Completed

Multiple Oral Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PF-04878691

Hepatitis C Virus

United States
Sorlandet Hospital HF

Completed

Mechanisms of Retinal Revascularization and Clinical Indicators of Neovascular AMD Relapse

Wet Macular Degeneration

Norway
Bayer
Regeneron Pharmaceuticals

Completed

Japanese Treat and Extend Study of Aflibercept in Neovascular Age-related Macular Degeneration (ALTAIR)

Wet Macular Degeneration

Japan
Bayer
Regeneron Pharmaceuticals

Completed

Eylea Post Marketing Surveillance(PMS)

Macular Degeneration

Korea, Republic of
Bayer
Regeneron Pharmaceuticals

Completed

Aflibercept (Eylea) in roUtine Clinical Practice in patientS With Wet Age-related Macular Degeneration in Italy (PERSEUS-IT)

Wet Macular Degeneration

Italy

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