Search clinical trials for: Aliskiren/HCTZ

Total 386 results

Merck Sharp & Dohme LLC

Terminated

Dose-ranging Study to Evaluate the Effectiveness and Tolerability of MK0736 in Patients With Type 2 Diabetes Mellitus (T2DM) and Hypertension (0736-007)

Hypertension | Type 2 Diabetes Mellitus
Boehringer Ingelheim

Completed

Relative Bioavailability of Telmisartan and HCTZ in Two Experimental Formulations Compared to the Standard Formulation Telmisartan and HCTZ in Healthy Female and Male Subjects

Healthy
Menarini Group
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Completed

Olmesartan/HCTZ 40/12.5 mg Combination Therapy Versus Olmesartan Medoxomil 40 mg Monotherapy in Essential Hypertension

Hypertension

Poland, Germany, Israel, Romania, Italy, Denmark, Czechia, Croatia
Novartis Pharmaceuticals

Completed

Effects of Aliskiren, Ramipril, and the Combination on Levels of Angiotensin II in Patients With Decompensated Systolic Heart Failure (ESCAPE-SHF)

Heart Failure

Russian Federation, Germany, Poland
Merck Sharp & Dohme LLC

Completed

Multiple Dose Effects of Hydrochlorothiazide and Isosorbide Mononitrate on Glucose Homeostasis (MK-0000-117)(Completed)

Hypertension
University of Colorado, Denver
American Heart Association

Terminated

Clinical Pharmacology of Aliskiren in Combination With Cyclosporine in Cardiac Transplantation

Hypertension | Cardiac Transplantation

United States
Novartis
The TIMI Study Group

Completed

Efficacy and Safety of Aliskiren and Valsartan Versus Placebo in Patients Stabilized Following an Acute Coronary Syndrome

Myocardial Ischemia | Post Acute Coronary Syndrome

Germany, Spain, United States, Belgium, Canada, Czech Republic, Hungary, Netherlands, Poland, Russian Federation, Sweden
Merck Sharp & Dohme LLC

Completed

A Study of MK-7145 Compared to Placebo and Hydrochlorothiazide for Lowering Blood Pressure in Male Participants With Hypertension (MK-7145-009)

Hypertension
Sir Mortimer B. Davis - Jewish General Hospital
Novartis Pharmaceuticals

Withdrawn

Aliskiren vs Hydrochlorothiazide in Hypertensive Type II Diabetic Patients on Resistance Arteries

Hypertension | Diabetes

Canada
Merck Sharp & Dohme LLC

Completed

The Effect of Hypertension Medications on Renal Blood Flow Measurements in Healthy Males (MK-0000-127)

Hypertension
Novartis

Completed

8-week Study to Evaluate Safety and Efficacy of Various Combinations of Valsartan, HCTZ, and Amlodipine in Patients With Moderate to Severe Hypertension

Hypertension

United States
Novartis Pharmaceuticals

Completed

Comparison of Aliskiren and Amlodipine on Insulin Resistance and Endothelial Dysfunction in Patients With Hypertension and Metabolic Syndrome

Metabolic Syndrome | Insulin Resistance | Endothelial Dysfunction | High Blood Pressure

United States
University Hospital, Toulouse
Sanofi; EUCLID Clinical Trial Platform; Cure Parkinson; Réseau NS-Park

Completed

Study to Evaluate the Effect of Lixisenatide in Patient With Parkinson's Disease (LixiPark)

Parkinson Disease

France
Novartis Pharmaceuticals

Completed

ALiskiren or Losartan Effects on bioMARKers of Myocardial Remodeling (ALLMARK)

Hypertension | Left Ventricle Hypertrophy

Spain
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Valsartan/Hydrochlorothiazide Combination Compared to Valsartan Monotherapy or Hydrochlorothiazide Monotherapy in Elderly (>70) With Mild-moderate Hypertension.

Hypertension

United States
AstraZeneca

Completed

Antihypertensive Efficacy and Safety of Candesartan/HCT 32/25 mg in Comparison With Individual Components and Placebo

Hypertension

Russian Federation, Latvia, Romania, Slovakia, Belgium, Malta
Boehringer Ingelheim

Completed

Bioequivalence of Telmisartan/ HCTZ Fixed Dose Combination Compared With Its Monocomponents in Healthy Male Volunteers II

Healthy
Novartis Pharmaceuticals

Completed

Aliskiren in Combination With Losartan Compared to Losartan on the Regression of Left Ventricular Hypertrophy in Overweight Patients With Essential Hypertension (ALLAY)

Hypertension | Overweight | Left Ventricular Hypertrophy

United States, Finland, Sweden, Germany, Italy, Spain, Argentina, Colombia, Russian Federation
Centers for Disease Control and Prevention
University of Miami; Nova Southeastern University; DePaul University

Completed

Proyecto SOL: A Risk Reduction Intervention for Hispanic Men Who Have Sex With Men (MSM)

HIV Infections

United States
Novartis

Completed

Valsartan/Amlodipine As Compared to Losartan Treatment in Stage 2 Systolic Hypertension (EXALT)

Stage 2 Systolic Hypertension

United States
Novartis

Completed

Efficacy and Safety of Valsartan/Hydrochlorothiazide Combination Therapy in Patients With Hypertension

Hypertension

United States
Joanne Kurtzberg, MD
The Marcus Foundation

Completed

hCT-MSCs for Children With Autism Spectrum Disorder (ASD) (hCT-MSCs)

Autism Spectrum Disorder | Autism | ASD

United States
Novartis

Terminated

Effects of Aliskiren and Amlodipine on the Renin-Angiotensin System (RAS) and Lipid/Carbohydrate Metabolism in Obese Patients With Hypertension

Hypertension | Abdominal Obesity

Germany
University of Maryland, Baltimore
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Salt Loading and Thiazide Intervention Study (SALTI)

Hypertension

United States
John Mascarenhas
National Cancer Institute (NCI); Novartis; Incyte Corporation; Myeloproliferative...

Terminated

Ruxolitinib Prior to Transplant in Patients With Myelofibrosis

Primary Myelofibrosis | Post Essential Thrombocythemia Myelofibrosis | Post Polycythemia Vera Myelofibrosis

United States, Canada, United Kingdom
Duke University
The Marcus Foundation

Completed

Open Label Phase I hCT-MSC in Toddlers With Autism Spectrum Disorder (TACT)

Autism Spectrum Disorder

United States
Boehringer Ingelheim

Completed

Bioequivalence of Telmisartan / HCTZ Fixed Dose Combination Compared to Its Monocomponents in Healthy Male Volunteers

Healthy
Boehringer Ingelheim

Completed

Bioequivalence of Telmisartan / HCTZ of Fixed Dose Combination Compared to Its Monocomponents in Healthy Male Volunteers

Healthy
Shiga University

Completed

Shiga Microalbuminuria Reduction Trial-2

Hypertension | Type 2 Diabetes Mellitus

Japan
Novartis Pharmaceuticals

Terminated

Assessment of Aliskiren/Amlodipine and Amlodipine on Ankle Foot Volume (AFV) in Patients With Hypertension

Hypertension | Ankle Edema

Netherlands
Novartis

Completed

Pharmacokinetic Drug Interaction Study Following Co-administration of Valsartan, Hydrochlorothiazide and Amlodipine in Patients With Hypertension

Hypertension

India
Merck Sharp & Dohme LLC

Completed

A Study to Investigate the Magnitude and Duration of Response of MK0954 Compared to Placebo in Patients With Hypertension (0954-021)(COMPLETED)

Hypertension
Boehringer Ingelheim

Completed

Telmisartan/Hydrochlorothiazide (HCTZ) Fixed Dose Combination Compared to Its Monocomponents in Healthy Subjects

Healthy
Joanne Kurtzberg, MD
Duke Clinical and Translational Science Institute (CTSI), part of the NIH...

Completed

Study of hCT-MSC in Newborn Infants With Moderate or Severe HIE

Moderate to Severe Hypoxic-ischemic Encephalopathy

United States
Duke University

Completed

In Person and mHealth Coping Skills Training for Symptom Management and Steps in Stem Cell Transplant Patients (Symptoms-Steps)

Stem Cell Transplant

United States
Faculty Sao Leopoldo Mandic Campinas

Unknown

Endodontic Treatment Using CTZ Paste in Primary Teeth (SLM2204)

Pulpectomy Agents

Brazil
Novartis

Terminated

Antialbuminuric Effects of Valsartan and Lisinopril

Hypertension | Early Diabetic Nephropathy

Switzerland
Bristol-Myers Squibb
Sanofi

Completed

Irbesartan/Hydrochlorothiazide (HCTZ) Combination Therapy for Patients With Moderate Hypertension

Hypertension

United States, Canada, Germany, Russian Federation, France
University of Maryland, Baltimore
King Pharmaceuticals is now a wholly owned subsidiary of Pfizer

Terminated

Mechanisms of Ramipril Reduction in the Onset of Type 2 Diabetes

Metabolic Syndrome

United States
Daiichi Sankyo, Inc.
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Completed

Combination of Olmesartan and Hydrochlorothiazide in Essential Hypertension

Essential Hypertension

Belgium, Germany, Netherlands, Slovakia
National Taiwan University Hospital

Recruiting

The Analysis of Thyroidectomy and Parathyroidectomy

Parathyroid Diseases | Thyroid Diseases

Taiwan
Massachusetts General Hospital
Tesaro, Inc.

Completed

Niraparib + Dostarlimab + RT in Pancreatic Cancer

Pancreatic Cancer | Metastatic Pancreatic Cancer

United States
Organon and Co

Completed

Bioequivalence of Losartan and Hydrochlorothiazide (HCTZ) Combination Tablet and Coadministration of Its Components (0954A-306)

Hypertension
Novartis Pharmaceuticals

Completed

An Extension Study to Evaluate the Long Term Safety, Tolerability and Efficacy of Aliskiren Compared to Enalapril in Pediatric Hypertensive Patients 6-17 Years of Age

Hypertension

United States, Hungary, Turkey, Guatemala, Slovakia, Puerto Rico, Poland
Novartis

Completed

Safety and Efficacy of Aliskiren 300 mg, 150 mg and 75 mg in Patients With Essential Hypertension Compared to Ramipril 5 mg

Hypertension

China, India, Thailand
Boehringer Ingelheim

Completed

Telmisartan80/HCTZ25 Versus Telmisartan80/HCTZ12.5 in Hypertension Not Responding to Telmisartan80/HCTZ12.5

Hypertension

France, Switzerland, Italy, Germany, Hong Kong, Netherlands, South Africa, Spain, Taiwan, Denmark, Sweden, Finland, Ireland, Korea, Republic of, Malaysia, Norway
Masonic Cancer Center, University of Minnesota

Active, not recruiting

Reduced Intensity (RIC) Conditioning And Transplantation of HLA-Haplo-HCT

Hematologic Malignancies

United States
Brigham and Women's Hospital

Terminated

Assessment of Renin Inhibition on Insulin Sensitivity, Diastolic Function and Aortic Compliance

Insulin Sensitivity | Diastolic Function | Aortic Compliance

United States
Boehringer Ingelheim

Completed

Trial of Telmisartan 80 mg/HCTZ 12.5 mg and Telmisartan 40 mg/HCTZ 12.5 mg in Patients With Hypertension

Hypertension

Japan
Novartis Pharmaceuticals

Completed

Safety/Efficacy of Valsartan/Hydrochlorothiazide Combination Compared to Hydrochlorothiazide in Obese Hypertensive Adults

Hypertension

United States

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