Search clinical trials for: Alpha-glucosidase inhibitor

Total 68428 results

Peking University Third Hospital

Recruiting

Treatment of Oral Lichen Planus With Paeoniflorin and Photodynamic Therapy

Oral Lichen Planus

China
Genzyme, a Sanofi Company

Completed

Study to Compare the Efficacy and Safety of Enzyme Replacement Therapies Avalglucosidase Alfa and Alglucosidase Alfa Administered Every Other Week in Patients With Late-onset Pompe Disease Who Have Not Been Previously Treated for Pompe Disease (COMET)

Glycogen Storage Disease Type II;Pompe's Disease

Czechia, Taiwan, Belgium, Germany, Korea, Republic of, United States, Argentina, Australia, Austria, Brazil, Canada, Denmark, France, Hungary, Italy, Japan, Mexico, Netherlands, Poland, Portugal, Russian Federation, Spain, Switzerland, Turk... and more
Stanford University

Withdrawn

Pilot Study of alpha1-antitrypsin to Treat Neuromyelitis Optica Relapses (A1AT for NMO)

Neuromyelitis Optica

United States
Grifols Therapeutics LLC

Enrolling by invitation

Long Term Safety of Alpha1-Proteinase Inhibitor in Subjects With Alpha1 Antitrypsin Deficiency (SPARTA-OLE)

Pulmonary Emphysema in Alpha-1 Antitrypsin Deficiency

United States, New Zealand, Denmark, Australia, Finland, Estonia, Canada, Poland, Russian Federation, Sweden, France
GlaxoSmithKline

Completed

Establishing the Benefits of Adherence to Enlarged Prostate Treatment: A Validation Study Linking Adherence to Outcomes Using the Market Scan Database

Prostatic Hyperplasia
Grifols Therapeutics LLC
Grifols Japan K.K.

Completed

Safety and Pharmacokinetics of Alpha-1 MP (Alpha1-proteinase Inhibitor (Human), Modified Process) in Participants With Alpha1-Antitrypsin Deficiency

Alpha1-Antitrypsin Deficiency

Japan
Soroka University Medical Center

Unknown

Single Dose Administration of Alpha-1 Anti-Trypsin for the Amelioration of Organ Injury in Patients Undergoing Cardiac Surgery

Post Cardiac Surgery Systemic Inflammatory Response
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI); Peloton Therapeutics, Inc.

Completed

HIF-2 Alpha Inhibitor PT2385 in Treating Patients With Recurrent Glioblastoma (PT2385)

Recurrent Glioblastoma

United States
Grifols Therapeutics LLC
Grifols Japan K.K.

Completed

Long-term Safety of Alpha1-Proteinase Inhibitor (Human) in Japanese Subjects With Alpha1 Antitrypsin Deficiency (GTI1401-OLE)

Alpha1-Antitrypsin Deficiency

Japan
John Levine
National Cancer Institute (NCI)

Completed

A Proof of Concept Pilot Trial of Alpha-1-Antitrypsin for Pre-Emption Of Steroid-Refractory Acute GVHD

GVHD | Graft-versus-host-disease

United States
Yamo Pharmaceuticals LLC

Active, not recruiting

A 12-Week Crossover Study to Assess the Efficacy, Safety and Tolerability of L1-79 in Subjects Aged 12-21 Years With Autism Spectrum Disorder

Autism Spectrum Disorder | Autism

United States
Grifols Therapeutics LLC

Completed

A Study to Assess Safety and PK of Liquid Alpha₁-Proteinase Inhibitor (Human) in Treating Alpha₁-Antitrypsin Deficiency

Alpha₁-Antitrypsin Deficiency

United States
National Institute of Allergy and Infectious Diseases...
Juvenile Diabetes Research Foundation; Immune Tolerance Network (ITN)

Terminated

A Research Trial of Aralast in New Onset Diabetes (RETAIN) (RETAIN)

Diabetes Mellitus, Type 1

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Recruiting

Rintatolimod, Celecoxib and Interferon Alpha 2b With Pembrolizumab For the Treatment of Patients With Metastatic or Unresectable Triple Negative Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8 | Metastatic Triple-Negative Breast Carcinoma | Unresectable Triple-Negative Breast Carcinoma

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Recruiting

Polarized Dendritic Cell (aDC1) Based Treatment, Interferon Alpha-2, Rintatolimod, and Celecoxib for the Treatment of HLA-A2+ Refractory Melanoma

Refractory Melanoma | HLA-A2 Positive Cells Present

United States
University of California, Los Angeles

Completed

Effectiveness of CES on Emotional and Cellular Wellbeing

Depression | Anxiety

United States
Eli Lilly and Company

Completed

A Study of LY2608204 in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

Singapore, United States
Eli Lilly and Company

Terminated

A Study of LY2599506 (Oral Agent Medication: Glucokinase Activator 1) in Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

Russian Federation, Spain, Germany, Australia, Austria, Israel, Czech Republic
Boehringer Ingelheim

Completed

Study to Evaluate the Therapeutic Action of Tamsulosin and Finasteride in Symptomatic Benign Prostatic Hyperplasia (BPH) Patients

Prostatic Hyperplasia
Hoffmann-La Roche

Completed

Bevacizumab in Metastatic Renal Cancer

Renal Cell Cancer

Germany
Grifols Therapeutics LLC

Active, not recruiting

Efficacy and Safety of Alpha1-Proteinase Inhibitor (Human), Modified Process (Alpha-1 MP) in Subjects With Pulmonary Emphysema Due to Alpha1 Antitrypsin Deficiency (AATD) (SPARTA)

Pulmonary Emphysema in Alpha-1 PI Deficiency

United States, Australia, Denmark, New Zealand, Estonia, Poland, Russian Federation, Sweden, Brazil, Canada, France, Finland
Mount Vernon Cancer Centre at Mount Vernon Hospital

Unknown

MRI Scans of Blood Vessel Changes Caused by Bevacizumab Alone or Given Together With Interferon Alpha-2a in Treating Patients With Stage III or Stage IV Kidney Cancer

Kidney Cancer

United Kingdom
University of Birmingham
Novartis; National Cancer Institute, France; MPN Voice

Recruiting

MITHRIDATE: Ruxolitinib Versus Hydroxycarbamide or Interferon as First Line Therapy in High Risk Polycythemia Vera (MITHRIDATE)

Polycythemia Vera

United Kingdom
The Cleveland Clinic

Completed

Differentiating Unipolar and Bipolar Depression in Young Adults Using fMRI

Bipolar Disorder | Major Depression

United States
University of Vienna

Recruiting

Hop Compounds on the Immune System (VH)

Inflammatory Response

Austria
Virginia Commonwealth University

Completed

Alpha-1 Anti-Trypsin (AAT) Treatment in Acute Myocardial Infarction (VCU-Alpha1RT)

Acute Myocardial Infarction

United States
EMS

Not yet recruiting

Efficacy and Safety of the DTT106 in the Treatment of Erectile Dysfunction Associated With Benign Prostatic Hyperplasia (AUSTRÁLIA)

Erectile Dysfunction | Prostatic Hyperplasia, Benign

Brazil
Christina Murphey, RN, PhD

Suspended

New Mothers Alpha-Stim

Depression | Insomnia | Anxiety | Sleep Quality

United States
Children's Hospital Medical Center, Cincinnati
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Alpha Auditory Entrainment for Cognitive Enhancement and Sensory Hypersensitivity in Youth With Developmental Disorders (ENTRAIN)

Autism Spectrum Disorder | Autistic Disorder | Fragile X Syndrome | Asperger Syndrome

United States
Christina Murphey, RN, PhD

Terminated

Efficacy of CES in New Mothers During the Post Partum Period

Depression | Insomnia | Anxiety | Sleep Quality

United States
Merck Sharp & Dohme LLC

Completed

PegIntron Treatment of Chronic Hepatitis B e Antigen-Positive Patients (P05170/MK-4031-327)

Hepatitis B, Chronic
Electromedical Products International, Inc.
University of Nottingham

Recruiting

Alpha-Stim AID and Major Depressive Disorder

Depressive Disorder, Major

United Kingdom
Institute for Human Genetics and Biochemistry
Grifols Biologicals, LLC; AIDS Community Research Initiative of America

Terminated

Safety and Efficacy of (α1Proteinase Inhibitor, α1PI) in HIV Disease

HIV Disease

United States
GlaxoSmithKline

Completed

Comparative Efficacy of Dutasteride Plus Tamulosin With Lifestyle Advice Versus Watchful Waiting Plus Lifestyle Advice in the Management of Treatment naïve Men With Moderately Symptomatic Benign Prostatic Hyperplasia and Prostate Enlargement (CONDUCT)

Prostatic Hyperplasia

Italy, Spain, United Kingdom, Netherlands, Greece, Romania, France, Germany
GlaxoSmithKline

Completed

This Will be an Open-label, Three-period, Fixed-sequence Study to Evaluate the Drug-drug Interaction, Pharmacokinetics and Safety of Dutasteride and Tamsulosin When Administered Alone and In-combination in Chinese Healthy Male Volunteers. The Study Will Last Approximately Eleven Weeks. Blood Samples

Prostatic Hyperplasia

China
Institute of Liver and Biliary Sciences, India

Withdrawn

'Tenofovir Pulse and Peg Interferon Alpha 2b' Therapy in HBeAg-positive Patients With Normal ALT

HBV

India
Case Comprehensive Cancer Center
GlaxoSmithKline

Completed

Study of Tamsulosin and/or Dutasteride to Relieve Urinary Symptoms After Brachytherapy for Localized Prostate Cancer

Prostate Cancer

United States
Boehringer Ingelheim

Completed

Study to Investigate the Effect of Ketoconazole Mediated CYP3A4 Inhibition on Pharmacokinetics of Tamsulosin in Healthy Male Volunteers

Healthy
InVasc Therapeutics, Inc.

Completed

Effects of Quinapril 40 mg With Alpha Lipoic Acid or Placebo on Diabetes and Hypertension (QUALITY)

Hypertension | Diabetes

United States
Columbia University
Alpha-1 Foundation; Stony Wold-Herbert Fund, Inc.

Completed

Targeting Pulmonary Perfusion in Alpha-1 Antitrypsin Deficiency

Chronic Obstructive Pulmonary Disease | Emphysema | Alpha-1 Antitrypsin Deficiency

United States
GlaxoSmithKline

Terminated

Safety and Efficacy of 0.5mg Dutasteride and 0.4mg Tamsulosin Combination Once Daily for Six Months for Benign Prostatic Hyperplasia (FDC114785)

Prostatic Hyperplasia

Vietnam
GlaxoSmithKline

Completed

Prospective Sexual Function Study for BPH Subjects

Prostatic Hyperplasia

Germany, Australia, Netherlands, Spain, Hungary, France, Greece
Eli Lilly and Company

Completed

A Study Comparing Insulin Peglispro With Insulin Glargine as Basal Insulin Treatment

Type 2 Diabetes Mellitus

Japan, Taiwan, Korea, Republic of
ANRS, Emerging Infectious Diseases
Bristol-Myers Squibb

Completed

Therapy With Asunaprevir, Daclatasvir, Ribavirin and Pegylated Interferon Alpha-2a in HCV Genotype 4-infected Patients Who Have Failed to a Previous Therapy With Peg-Interferon/Ribavirin (ANRS HC32 QUATTRO)

Hepatitis C Virus Genotype 4 Infection

France
Xijing Hospital
Henan Provincial People's Hospital; The First Affiliated Hospital of Dalian...

Completed

Efficacy and Safety Study of Total Glucosides of Paeony Combined With Acitretin to Treat Psoriasis

Psoriasis

China
Pennington Biomedical Research Center
Quest Nutrition LLC

Withdrawn

The Effect of Oral Alpha-Cyclodextrin on Fecal Fat Excretion (FAT ABSORBER)

Obesity | Cardiovascular Disease

United States
Leiden University Medical Center
University Medical Center Groningen

Completed

Feasibility of the Combination of Chemotherapy (Carbo/Caelyx or Carbo/Doxorubicin) With Tocilizumab (mAb IL-6R) and Peg-Intron in Patients With Recurrent Ovarian Cancer (PITCH)

Recurrent Ovarian Cancer

Netherlands
Genzyme, a Sanofi Company

Active, not recruiting

A Study to Assess Safety and Efficacy of Avalglucosidase Alfa Administered Every Other Week in Pediatric Patients With Infantile-onset Pompe Disease Previously Treated With Alglucosidase Alfa (Mini-COMET)

Glycogen Storage Disease Type II-Pompe's Disease

United States, France, Japan, Taiwan, United Kingdom
Third Military Medical University

Completed

Liraglutide Improve Cognitive Function in Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

China
National Institute of Diabetes and Digestive and...
George Washington University

Completed

Medical Therapy of Prostatic Symptoms (MTOPS)

Prostatic Hyperplasia | Prostatic Hypertrophy, Benign

United States

Search clinical trials for: Alpha-glucosidase inhibitor

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