Search clinical trials for: Amiloride, hydrochlorothiazide

Total 453 results

University of North Carolina, Chapel Hill

Completed

Do Acid Sensing Ion Channels Contribute to Heartburn?

Gastroesophageal Reflux Disease | Heartburn

United States
Mylan Pharmaceuticals Inc

Completed

Fed Study of Benazepril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg to Lotensin HCT® Tablets 20 mg/25 mg

Healthy

United States
Organon and Co

Completed

Hydrochlorothiazide (+) Losartan Potassium vs. Amlodipine Comparative Study (0954A-314)

Essential Hypertension
EMS

Withdrawn

Efficacy and Safety of Candesartan Associated With Chlorthalidone Versus Losartan Associated With Hydrochlorothiazide (Hyzaar®) in Essential Hypertension Control

Essential Arterial Hypertension
Torrent Pharmaceuticals Limited

Completed

BE Study of Torrent's Olmesartan Medoxomil, Amlodipine and Hydrochlorothiazide Tab - Fed Conditions

Healthy Subjects
Novartis

Completed

Aliskiren and the Calcium Channel Blocker Amlodipine Combination as an Initial Treatment Strategy for Hypertension (ACCELERATE)

Hypertension

Switzerland, United Kingdom, Venezuela, France, South Africa, Greece, Canada, Costa Rica, Germany, Guatemala
Takeda

Completed

Efficacy and Safety of Candesartan Cilexetil Plus Hydrochlorothiazide in Subjects With Severe Hypertension

Hypertension

Ukraine, Germany
Daiichi Sankyo, Inc.

Completed

An Examination of the Blood Pressure Lowering Ability and Safety of Olmesartan Medoxomil in Elderly Patients With Hypertension

Hypertension

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Quinapril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg to Accuretic™ Tablets 20 mg/25 mg

Healthy

United States
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Benazepril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg to Lotensin HCT® Tablets 20 mg/25 mg

Healthy

United States
Novartis Pharmaceuticals

Completed

A Long-term (12 Months) Safety, Tolerability and Efficacy Study of LCZ696 in Patients With Essential Hypertension

Essential Hypertension

China, Taiwan, Japan, Thailand, Korea, Republic of
Centre Hospitalier Universitaire de Nice

Unknown

Acid-Sensing Ion Channel and Migraine Disease Proof of Concept Study on the Efficacy of Amiloride in the Prophylaxis of Migraine Aura (APAM)

Migraine With Aura

France
Cairo University

Unknown

Rectal Misoprostol and Blood Loss During Abdominal Hysterectomy

Blood Loss

Egypt
Chong-Jin Kim
Hanmi Pharmaceutical Company Limited

Completed

Comparison of Effects Between Amlodipine and Hydrochlorothiazide in Combination With Losartan on 24-hr Central Blood Pressure in Hypertensive Patients

Hypertension

Korea, Republic of
Organon and Co

Terminated

A Study of Losartan Compared to Losartan/HCTZ in Pediatric Patients With Hypertension (0954A-327)

Hypertension
Mylan Pharmaceuticals Inc

Completed

Food Study of Quinapril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg to Accuretic™ Tablets 20 mg/25 mg

Healthy

United States
Organon and Co

Completed

MK0954A-264 Filter Study (0954A-264)(COMPLETED)

Mild to Severe Hypertension
Merck KGaA, Darmstadt, Germany

Completed

An Observational Study to Evaluate the Efficacy of Lodoz in a Population of Hypertensive Patients (Lodoz OS)

Hypertension

Thailand
Jichi Medical University

Completed

The Japan-Combined Treatment With Olmesartan and a Calcium Channel Blocker Versus Olmesartan and Diuretics Randomized Efficacy Study (J-CORE)

Hypertension

Japan
Organon and Co

Completed

LAAS (Losartan Anti-Atherosclerosis Study)(0954-330)(COMPLETED)

Hypertension
University of Utah
Center for Addiction and Mental Health

Active, not recruiting

Pharmacokinetics of Amiloride Nasal Spray in Healthy Volunteers

Pharmacokinetics

United States
University of Oxford
Multiple Sclerosis Society of Great Britain and Northern Ireland

Completed

Amiloride Clinical Trial In Optic Neuritis (ACTION)

Multiple Sclerosis | Optic Neuritis

United Kingdom
Ib Abildgaard Jacobsen

Completed

Amiloride for Resistant Hypertension

Hypertension | Type 2 Diabetes Mellitus | Microalbuminuria

Denmark
Shire
Takeda Development Center Americas, Inc.

No longer available

Expanded Access for the Prevention of Acute Attacks of 1) Hereditary Angioedema (HAE) in Children and 2) Non-histaminergic Angioedema With Normal C1-Inhibitor (C1-INH) in Teenagers and Adults

Angioedema | Hereditary Angioedema (HAE)

United States, Canada, Germany, Hungary, Spain
Chinese Academy of Medical Sciences, Fuwai Hospital

Unknown

Effects of Angiotensin II Receptor Blocker Compared With Diuretics in High-risk Hypertensive Patients (CHIEF)

Essential Hypertension

China
Tokyo University

Completed

Evaluation of Effect of Combination With Telmisartan and Hydrochlorothiazide in Hypertensives Uncontrolled on Amlodipine (ONEAST)

Essential Hypertension

Japan
Assistance Publique - Hôpitaux de Paris

Completed

PHARES Study: Management of Resistant Hypertension

Hypertension

France
University of Kansas Medical Center

Recruiting

Mitigating the Pro-inflammatory Phenotype of Obesity (MAPLE)

Obesity | Diabetes | Insulin Resistance | Blood Pressure | Diuretics Drug Reactions | Sympathetic Nerve Activity

United States
Mylan Pharmaceuticals Inc

Completed

Fed Study of Olmesartan Medoxomil and Hydrochlorothiazide Tablets 40 mg/25 mg and Benicar HCT® Tablets 40 mg/25 mg

Healthy

United States
Laboratorios Silanes S.A. de C.V.

Completed

Efficacy and Safety of Losartan/Chlorthalidone vs Losartan/Hydrochlorothiazide in Essential Arterial Hypertension

Essential Arterial Hypertension

Mexico
EMS

Suspended

Comparison of Losartan Associated With Indapamide Versus Hyzaar® in the Hypertension Treatment

Hypertension

Brazil
Merck Sharp & Dohme LLC

Completed

Multiple Dose Effects of Hydrochlorothiazide and Isosorbide Mononitrate on Glucose Homeostasis (MK-0000-117)(Completed)

Hypertension
Forest Laboratories

Completed

Combination of Nebivolol and Valsartan Given as Free Tablets for Stage 1 or Stage 2 Hypertension

Hypertension

United States
UMC Utrecht
Novartis Pharmaceuticals

Completed

Treatment of Adiposity Related hypErTension (TARGET) (TARGET)

Hypertension | Metabolic Syndrome | Abdominal Obesity

Netherlands
Schering-Plough

Completed

Assessment of the Effectiveness of OLMETEC® and OLMETEC PLUS® for Treatment of Hypertension in Stage I and II Patients (Study P05254)(COMPLETED)

Hypertension
Parc de Salut Mar

Completed

Generation of Biological Samples Positive to Hydrochlorothiazide for Anti-doping Control (HCTZ)

Healthy Volunteers

Spain
Assistance Publique - Hôpitaux de Paris

Terminated

Dose-Dependent Effect of Thiazide in Dent's Disease Hypercalciuria (DESY)

Nephrolithiasis | Dent's Disease

France
EMS

Not yet recruiting

Efficacy and Safety of Olmesartan Associated With Chlorthalidone in Essential Arterial Hypertension Control

Essential Arterial Hypertension
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Olmesartan Medoxomil and Hydrochlorothiazide Tablets 40 mg/25 mg and Benicar HCT® Tablets 40 mg/25 mg

Healthy

United States
Pharmtechnology LLC
Ligand Research, LLC

Completed

Bioequivalence Study of Two Formulations of Tablets Ramipril/Hydrochlorothiazide 10 mg/25 mg in Healthy Volunteers Under Fasting Conditions

Bioequivalence

Russian Federation
Novartis

Completed

A Study to Evaluate the Combination of Valsartan and Amlodipine in Hypertensive Patients Not Controlled on Monotherapy

Hypertension

Switzerland
GlaxoSmithKline

Completed

Examining the Effect of Different Diuretics on Fluid Retention in Diabetics Treated With Rosiglitazone.

Diabetes Mellitus

France, Poland, Germany, Netherlands, Spain, Greece, Slovakia, Italy, United Kingdom, Denmark, Belgium, Norway, Canada, Israel
Novartis

Completed

Efficacy and Safety of Valsartan, Hydrochlorothiazide and Amlodipine Combination Therapy in Hypertension

Hypertension

Brazil
University of British Columbia
Canadian Institutes of Health Research (CIHR)

Completed

Behavioural Treatment of Hypertension

Hypertension

Canada
Brigham and Women's Hospital
Johns Hopkins University; National Institute on Aging (NIA); Rutgers University

Active, not recruiting

Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Amiloride vs Triamterene

Hypertension

United States
University of North Carolina, Chapel Hill
Wake Forest University Health Sciences; Cornell University

Completed

A Pilot Study of Plasma Renin Activity Guided vs Generic Combination Therapy for Hypertension

Hypertension | Plasma Renin Activity

United States
Georgetown University

Unknown

A Crossover Pilot Study of the Effect of Amiloride on Proteinuria

Proteinuria

United States
Oregon Health and Science University
Oregon Clinical and Translational Research Institute

Completed

A Translational Approach to Gitelman Syndrome

Gitelman Syndrome

United States
Novartis

Completed

Aliskiren Plus HCTZ Compared to Aliskiren in Metabolic Syndrome Patients With Stage 2 Systolic Hypertension (AIMS)

Hypertension

United States
Boryung Pharmaceutical Co., Ltd

Completed

A Study to Evaluate the Safety and Pharmacokinetics After Oral Concurrent Administration of Fimasartan and Hydrochlorothiazide in Healthy Male Volunteers

Essential Hypertension

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