Search clinical trials for: Antiprotozoal Agents

Total 188824 results

Virginia Commonwealth University
GlaxoSmithKline; Puma Biotechnology, Inc.

Recruiting

Niraparib and Neratinib in Advanced Solid Tumors With Expansion Cohort in Advanced Ovarian Cancer (iNNOVATE)

Ovarian Cancer | Advanced Solid Tumor

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Dabrafenib, Trametinib, and IMRT in Treating Patients With BRAF Mutated Anaplastic Thyroid Cancer

Thyroid Gland Anaplastic Carcinoma | BRAF V600K Mutation Present | BRAF NP_004324.2:p.V600E

United States
National Cancer Institute (NCI)

Active, not recruiting

Erlotinib Hydrochloride and Cabozantinib-s-Malate Alone or in Combination as Second or Third Line Therapy in Treating Patients With Stage IV Non-small Cell Lung Cancer

Recurrent Lung Non-Small Cell Carcinoma | Stage IV Lung Non-Small Cell Cancer AJCC v7

United States
Pfizer

Completed

Real-World Effectiveness of Palbociclib in Combination With an Aromatase Inhibitor

Metastatic Breast Cancer

United States
Merck Sharp & Dohme LLC
Pfizer

Active, not recruiting

Ertugliflozin Type 2 Diabetes Mellitus (T2DM) Pediatric Study (MK-8835/PF-04971729) (MK-8835-059)

Type 2 Diabetes Mellitus

United States, Belgium, Canada, Colombia, Costa Rica, Dominican Republic, France, Guatemala, Hungary, Israel, Italy, Malaysia, Mauritius, Mexico, Philippines, Poland, Russian Federation, Saudi Arabia, Turkey, Ukraine, United Arab... and more
Mylan Pharmaceuticals Inc

Completed

Fed Study of Finasteride Tablets 5 mg and Proscar® Tablets 5 mg

Healthy

United States
Hospital JP Garrahan
Hospital San Juan de Dios, Santiago

Active, not recruiting

Treatment Protocol for Non-Metastatic Unilateral Retinoblastoma (RbGALOP2)

Unilateral Retinoblastoma

Argentina
AbbVie

Completed

A Study to Compare Safety and Efficacy of Upadacitinib to Dupilumab in Adult Participants With Moderate to Severe Atopic Dermatitis (Heads Up)

Atopic Dermatitis

United States, Australia, Canada, Croatia, Czechia, Finland, France, Germany, Hungary, Ireland, Israel, Italy, Malaysia, Netherlands, New Zealand, Norway, Poland, Singapore, Spain, Sweden, Taiwan, Ukraine, United Kingdom
Carol Fabian, MD

Active, not recruiting

Pilot Study of Bazedoxifene Plus Conjugated Estrogen on Imaging and Blood Biomarkers

Increased Risk for Development of Breast Cancer

United States
Pfizer

Completed

A Study of Palbociclib (PD-0332991) + Letrozole vs. Letrozole For 1st Line Treatment Of Postmenopausal Women With ER+/HER2- Advanced Breast Cancer (PALOMA-2)

Breast Neoplasms

United States, Canada, Spain, United Kingdom, Australia, Belgium, Korea, Republic of, Japan, Czechia, France, Germany, Hungary, Ireland, Italy, Poland, Russian Federation, Taiwan, Ukraine
University of Redlands

Completed

Impact of Commercial "Sleep Lotion" on Salivary Melatonin Levels and Sleep Quality in Undergraduates

Sleep

United States
Massachusetts General Hospital

Active, not recruiting

Comparative Antiresorptive Efficacy Discontinuation of Denosumab

Osteoporosis | Osteoporosis, Postmenopausal

United States
University of Ottawa

Completed

What is the Nature of Pelvic Floor Muscle Involvement in Dyspareunia?

Dyspareunia

Canada
Sanofi

Completed

Comparison of Glucose Values and Variability Between TOUJEO and TRESIBA During Continuous Glucose Monitoring in Type 1 Diabetes Patients (inRange)

Type 1 Diabetes Mellitus

Turkey, Netherlands, Brazil, United States, Germany, Hungary, United Kingdom
3M

Completed

Closed Incision Negative Pressure Therapy Versus Standard of Care Surgical Dressing in Revision Total Knee Arthroplasty (PROMISES)

Pathologic Processes | Wounds and Injuries | Postoperative Complications | Surgical Wound | Infection | Musculoskeletal Disease | Prosthesis-Related Infections | Joint Disease | Revision Total Knee Arthroplasty

United States
Sanofi

Terminated

Efficacy and Safety of Sotagliflozin Versus Placebo in Chinese Patients With Type 2 Diabetes Mellitus Not Adequately Controlled by Diet and Exercise

Type 2 Diabetes Mellitus

China
Assistance Publique - Hôpitaux de Paris
Janssen, LP

Completed

Study of Dose Escalation of Abiraterone Actetate in Prostate Cancer (OPTIMABI)

Prostate Cancer

France
Lexicon Pharmaceuticals
Sanofi

Terminated

Efficacy and Bone Safety of Sotagliflozin 400 and 200 mg Versus Placebo in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control (SOTA-BONE)

Type 2 Diabetes Mellitus

United States, Australia, Canada, Korea, Republic of, Mexico, New Zealand, Russian Federation, Taiwan
Lexicon Pharmaceuticals
Sanofi

Completed

Efficacy and Safety of Sotagliflozin Versus Placebo and Empagliflozin in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control While Taking a DPP4 Inhibitor Alone or With Metformin (SOTA-EMPA)

Type 2 Diabetes Mellitus

United States, Bulgaria, Canada, Czechia, France, Italy, Latvia, Mexico, Russian Federation, Slovakia, Spain, United Kingdom
Incyte Corporation

Completed

A Study to Evaluate the Safety and Efficacy of Ruxolitinib Phosphate Cream Applied Topically to Adults With Atopic Dermatitis

Atopic Dermatitis

United States, Canada
Universidade Federal Fluminense

Completed

Transepidermal Application of Metilaminolevulinate in Daylight PDT in the Treatment of Photodamaged Skin

Skin Diseases

Brazil
Methodist Healthcare

Completed

Envarsus XL Immunosuppression Following Liver Transplantation

Recipients of Liver Transplant

United States
Canadian Network for Observational Drug Effect...
Canadian Institutes of Health Research (CIHR); Drug Safety and Effectiveness...

Completed

Direct Oral Anticoagulants in Patients With Atrial Fibrillation (DOACs vs DOACs)

Myocardial Infarction | Ischemic Stroke | Atrial Fibrillation | All-cause Mortality | Systemic Embolization | Major Bleed

Canada
Novartis Pharmaceuticals

Completed

Assess Bronchodilator Effect QVM149 Dosed Either in the Morning or Evening Compared to Placebo in Patients With Asthma (QVM149)

Asthma

Germany, Netherlands, United Kingdom
Bayer
Janssen Research & Development, LLC

Terminated

A Nationwide Observational Study Looking at Effectiveness and Bleeding Complications of NOACs vs. VKA in Non-valvular Atrial Fibrillation Patients. (PROTECT-AF)

Non-valvular Atrial Fibrillation

Norway
Bayer
Janssen Research & Development, LLC

Completed

Study to Compare the Effect of the Formulations (Orally Disintegrating Tablet and Film-coated Tablet) on Bioequivalence of Drug Rivaroxaban (Xarelto) at Dose of 10 mg in Japanese Healthy Male Adult Subjects

Clinical Pharmacology

Japan
Lexicon Pharmaceuticals
Sanofi

Completed

Efficacy, Safety, and Tolerability Study of Sotagliflozin as Adjunct Therapy in Adult Patients With Type 1 Diabetes Mellitus Who Have Inadequate Glycemic Control With Insulin Therapy (inTandem1)

Type 1 Diabetes Mellitus

United States, Canada
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Completed

DBPR108 Tablets in Type 2 Diabetes Mellitus Patients

Type 2 Diabetes Mellitus

China
Nobelpharma

Completed

Verification of the Efficacy of NPC-15 for Sleep Disorders of Children With Autism Spectrum Disorders (NPC-15-5)

Autism Spectrum Disorder | Sleep Disorders
Merck Sharp & Dohme LLC

Completed

A Phase II Trial of Ridaforolimus and Exemestane, Compared to Ridaforolimus, Dalotuzumab and Exemestane in Participants With Breast Cancer (MK-8669-064)

Breast Neoplasms
Elorac, Inc.

Completed

Finasteride Treatment of Severe Nodulocystic Acne

NODULOCYSTIC ACNE

United States
Sierra Oncology, Inc.

Terminated

Erlotinib and Momelotinib for the Treatment of Epidermal Growth Factor Receptor (EGFR) Mutated EGFR Tyrosine Kinase Inhibitor (TKI) Naive Metastatic Non-Small Cell Lung Cancer (NSCLC)

EGFR Mutated EGFR TKI Naive Metastatic NSCLC

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Terminated

Intensity-Modulated Radiation Therapy, Pemetrexed, and Erlotinib in Treating Patients With Recurrent or Second Primary Head and Neck Cancer

Head and Neck Cancer

United States
Karina Vejrum Sørensen

Unknown

Effect of Dietary Oils as G-protein-coupled Receptor Agonists on Glucose Tolerance

Obesity | Type 2 Diabetes Mellitus

Denmark
Cairo University

Unknown

Assessment of Immediate Implant Stability When Adding Mixture of Hyaluronic Acid and Melatonin

Immediate Dental Implant
Eli Lilly and Company

Completed

A Study of IMC-A12 in Combination With Sorafenib in Participants With Advanced Cancer of the Liver

Hepatocellular Carcinoma

United States
University of Nottingham

Completed

Characterizing the Incretin Effect of Amino Acids and Defining GLP-1 Role on Skeletal Muscle (Incretin)

Sarcopenia

United Kingdom
Boston Children's Hospital
International Rett Syndrome Foundation

Completed

Treatment of Rett Syndrome With Recombinant Human IGF-1

Rett Syndrome

United States
Seoul National University Hospital

Completed

Comparison Between 2L Coolprep® and Combination of 1L Coolprep® and Bisacodyl as Bowel Preparation

Bowel Preparation Before Colonoscopy | Healthy Person

Korea, Republic of
Medical University of Lodz

Completed

Biomarkers, Hemodynamic and Echocardiographic Predictors of Ischemic Strokes and Their Influence on the Course and Prognosis

Myocardial Infarction | Ischemic Stroke | Endocarditis | Patent Foramen Ovale | Embolic Stroke of Undetermined Source | Atrial Fibrillation and Flutter | Cardiac Tumor
Cornell University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Supplemental Selenium and Vitamin E and Pulmonary Function

Lung Diseases | Lung Diseases, Obstructive | Chronic Obstructive Pulmonary Disease
Bayer

Completed

Anticoagulation Preference by AF Patients Study (PRiSMA-AF)

Atrial Fibrillation

Switzerland
Charite University, Berlin, Germany
German Federal Ministry of Education and Research

Completed

Effects of Dietary Interventions on the Brain in Mild Cognitive Impairment (MCI)

Mild Cognitive Impairment

Germany
Tianjin Medical University Cancer Institute and...
Peking University First Hospital; The Affiliated Nanjing Drum Tower Hospital... and other collaborators

Unknown

Cryoablation Therapy or Radiotherapy Therapy for Stage III Prostate Cancer (CRYO-PCA-III)

Stage III Prostate Cancer

China
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Completed

Vaccine Therapy and Sargramostim in Treating Patients With Malignant Glioma

Glioblastoma | Gliosarcoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Giant Cell Glioblastoma | Recurrent Brain Neoplasm | Mixed Glioma

United States
Novo Nordisk A/S

Completed

Safety and Tolerability of NN9068 in Healthy Male Volunteers

Healthy | Diabetes

Germany
Janssen Research & Development, LLC
Bayer

Completed

A Study to Assess the Effects of 2 Different Prothrombin Complex Concentrates on the Pharmacodynamics of Rivaroxaban in Healthy Adult Volunteers

Healthy

Belgium
Novo Nordisk A/S

Completed

Observational Study on the Effect of NovoMix® 30, Levemir® or NovoRapid® (Alone or Combined) in Type 2 Diabetics Previously Treated With Anti-diabetic Medication (A1chieve®)

Diabetes Mellitus, Type 2 | Diabetes

Saudi Arabia, Algeria, Argentina, Bangladesh, China, Egypt, India, Indonesia, Iran, Islamic Republic of, Jordan, Korea, Republic of, Libyan Arab Jamahiriya, Malaysia, Mexico, Morocco, Pakistan, Philippines, Russian Federation and more
Sanofi

Completed

Pharmacodynamic Effects of Lixisenatide Compared to Liraglutide in Patients With Type 2 Diabetes Not Adequately Controlled With Insulin Glargine With or Without Metformin

Type 2 Diabetes Mellitus

Germany
Danderyd Hospital
Johnson & Johnson Consumer Products Company Division of Johnson & Johnson...

Active, not recruiting

Periprosthetic Bone Remodeling Around Uncemented Components in Total Hip Arthroplasty (PeriBRUSBRAC)

Osteoarthritis

Sweden

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