Search clinical trials for: Aprepitant Placebo

Total 54047 results

Yeditepe University Hospital

Completed

Prevention of Nausea and Vomiting in Patients After Surgery

Postoperative Nausea and Vomiting

Turkey
Fudan University

Completed

Adding Mirtazapine to Dexamethasone and Aprepitant for Delayed Emesis

Breast Cancer

China
John Paul II Hospital, Krakow
National Center for Research and Development, Poland; KCRI

Completed

Cardiovascular Clinical Project to Evaluate the Regenerative Capacity of CardioCell in Patients With Acute Myocardial Infarction (AMI)

Myocardial Infarction

Poland
Second Affiliated Hospital, School of Medicine,...

Not yet recruiting

Efficacy and Safety of Intravenous Versus Oral 5-HT3 Antagonists Combined With NK-1 Receptor Antagonists for the Prevention of CINV in Breast Cancer

Breast Cancer | Chemotherapy-induced Nausea and Vomiting

China
Xijing Hospital

Recruiting

Clinical on the Safety and Efficacy of Fosaprepitant Dimeglumine for Injection in the Prevention of CINV. (COSEFDIP)

Neoplasms

China
Shengjing Hospital

Completed

Efficacy of Chinese Herbal Medicine Xiaojidaozhi Decoction in the Treatment of Childhood Constipation

Constipation | Chinese Herbal Medicine

China
Odense University Hospital
Helsinn Healthcare SA

Completed

Efficacy of Two Antiemetic Regimens in Patients Receiving Radiotherapy and Concomitant Weekly Cisplatin (GAND-emesis)

Genital Neoplasms, Female | Nausea | Vomiting

Norway, Denmark, Germany, Australia
Instituto do Cancer do Estado de São Paulo

Completed

Neurokinin Receptor Antagonist Associated to Ondansetron in PONV (PONV)

Postoperative Nausea and Vomiting

Brazil
AstraZeneca

Completed

A Study of AZD8233 in Participants With Dyslipidemia. (HAYATE)

Dyslipidemia

Japan
PETHEMA Foundation
Merck Sharp & Dohme LLC

Completed

AMENO-2: Aprepitant Plus Palonosetron Versus Granisetron in the Prevention of Nausea and the Emesis Induced by Chemotherapy in Patients Treated With Haematopoietic Progenitors (AMENO-2)

Lymphoma | Leukemia

Spain
Albert Einstein College of Medicine

Completed

Sodium Bicarbonate Supplementation in Chronic Kidney Disease Evaluation of Dose Response, Safety and Beneficial Effects

Chronic Kidney Disease

United States
Heron Therapeutics

Completed

A Prospective, Multicenter, Study of APF530 (Granisetron) SC for Prevention of CINV in Patients Receiving HEC

Chemotherapy-induced Nausea and Vomiting

United States
Main Line Health
Merck Sharp & Dohme LLC; Drexel University College of Medicine

Unknown

Oral Aprepitant and Lower Dose Dexamethasone Versus Aprepitant Alone for Preventing Postoperative Nausea and Vomiting (PONV) After Elective Laparoscopic Surgeries

Nausea | Vomiting

United States
Sun Yat-sen University

Completed

Aprepitant Triple Therapy for the Prevention of CINV in Nondrinking and Young Women Who Received Moderately Emetogenic Chemotherapy (CINV)

Gastrointestinal Neoplasms | Chemotherapy-induced Nausea and Vomiting

China
Hospital Federal de Bonsucesso

Unknown

PALONOSETRON X FOSAPREPITANT IN PONV

Nausea and Vomiting, Postoperative

Brazil
Ashley Shoemaker

Enrolling by invitation

Theophylline for Treatment of Pseudohypoparathyroidism

Pseudohypoparathyroidism Type 1a | Albright Hereditary Osteodystrophy | Pseudohypoparathyroidism

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Greater Washington Community Foundation

Terminated

Muscadine Plus (MPX) In Men With Prostate Cancer

Adenocarcinoma of the Prostate

United States
Novartis Pharmaceuticals

Completed

A Study of Inclisiran in Participants With Homozygous Familial Hypercholesterolemia (HoFH) (ORION-5)

Homozygous Familial Hypercholesterolemia

Hong Kong, Israel, Russian Federation, Serbia, South Africa, Taiwan, Turkey, Ukraine
Ohio State University Comprehensive Cancer Center

Completed

Ondansetron Versus Palonosetron Antiemetic Regimen Prior to Highly Emetogenic Chemotherapy(HEC)

Malignant Neoplasm

United States
Vanderbilt University

Completed

Effect of Chronic ACE and DPP4 Inhibition on Blood Pressure

Hypertension | Type 2 Diabetes Mellitus

United States
Sun Yat-sen University
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Unknown

Olanzapine Plus Fosaprepitant Standard Antiemetic Therapy in the Prevention of Chemotherapy-induced Nausea and Vomiting in Patients Receiving High Emetic Risk Multi-day Chemotherapy: a Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 3 Study (OFFER)

Solid Tumor Patients Receiving High Emetic Risk Multi-day Chemotherapy

China
Montefiore Medical Center

Not yet recruiting

Antiemetic Fosaprepitant To Remedy Nausea and Vomiting (AFTR NV RCT)

Nausea | Vomiting | Nausea and Vomiting

United States
Samsung Medical Center
Dong-A ST Co., Ltd.

Unknown

Naftopidil 75mg for Improving Clearance of Urinary Stones

Kidney Calculi | Ureter Calculi

Korea, Republic of
Contera Pharma
Bukwang Pharmaceutical

Completed

A Study in Parkinson's Disease in Patients With Moderate to Severe Dyskinesia (ASTORIA)

Dyskinesias

France, Germany, Italy, Korea, Republic of, Spain
University of California, San Diego

Terminated

Phase 2 RCT of Alvimopan vs. Placebo After CRS/HIPEC (ILEUS)

Ileus

United States
Novartis

Completed

Efficacy and Safety of Diclofenac Sodium Topical Gel 1% Compared to Placebo in Subjects With Acute Blunt Trauma Injuries

Acute Blunt Soft Tissue Injuries/Contusions

United States
Fengmei Lian
Peking Union Medical College Hospital; Huashan Hospital; Chengdu University of... and other collaborators

Unknown

Post-marketing Evaluation of Mudan Granule Intervention on Type 2 Diabetic Peripheral Neuropathy

Diabetic Peripheral Neuropathy Type 2

China
William Beaumont Hospitals

Terminated

Effect of Probiotics in Non-alcoholic Fatty Liver Disease and Steatohepatitis (PRONE)

Fibrosis, Liver | Cirrhosis, Liver | Steatohepatitis, Nonalcoholic | Fatty Liver Disease

United States
Vanderbilt University
Merck Sharp & Dohme LLC

Withdrawn

Vorapaxar and Lower Extremity Bypass Grafts

Peripheral Artery Disease
Merck Sharp & Dohme LLC

Completed

A Korean Study of Efficacy and Safety of Aprepitant-based Triple Regimen for the Prevention of Chemotherapy-Induced Nausea and Vomiting in the First Cycle of Moderately Emetogenic Chemotherapy (Non-doxorubicin Hydrochloride [Adriamycin] and Cyclophosphamide Regimens) (MK-0869-225) (KMEC) (KMEC)

Nausea | Vomiting
Biogen

Recruiting

Pregnancy Exposure Registry for Vumerity (Diroximel Fumarate)

Multiple Sclerosis

Spain, Ireland, United States, Germany
Lawrence Einhorn
Merck Sharp & Dohme LLC; Hoosier Cancer Research Network

Completed

Fosaprepitant + 5HT3 Receptor Antagonists + Dexamethasone in Germ Cell Tumors

Chemotherapy-Induced Nausea and Vomiting

United States
University of Southern California
National Cancer Institute (NCI)

Terminated

Fosaprepitant Dimeglumine and Granisetron Transdermal System in Preventing Nausea and Vomiting in Patients With Breast Cancer Undergoing Chemotherapy

Breast Cancer | Nausea | Vomiting

United States
S. Maria Hospital, Terni

Terminated

Aprepitant in the Prevention of Delayed Emesis Induced by Cyclophosphamide Plus Anthracyclines in Breast Cancer Patients

Emesis

Italy
Smartfish AS

Completed

Pilot Study of Safety and Tolerability of Nutrifriend Cachexia in COPD Cachexia

Cachexia | COPD

Sweden
Smartfish AS

Completed

Pilot Study of Safety and Tolerability of Nutrifriend Cachexia in NSCLC Cachexia

NSCLC | Cachexia

Italy, Sweden, Croatia, Slovakia
Kuopio University Hospital

Withdrawn

Post-operative Corticosteroid Treatment After Mitral Valve Surgery (MitralPOCS)

Atrial Fibrillation

Finland
ISU Abxis Co., Ltd.

Unknown

Exploratory P2 Trial to Evaluate Efficacy and Safety of Clotinab® (Abciximab) in Acute MI Patients

Acute Myocardial Infarction

Korea, Republic of
Acacia Pharma Ltd

Completed

Dose-finding Study of APD403 to Prevent Nausea and Vomiting After Chemotherapy

CINV

Denmark
Ain Shams University

Completed

Effects of Aprepitant/Dexamethasone Versus Mertazepine /Dexamethasone on Postoperative Nausea and Vomiting

Nausea and Vomiting, Postoperative

Egypt
Merck Sharp & Dohme LLC

Completed

Efficacy and Safety of Fosaprepitant Dimeglumine in Preventing Chemotherapy-Induced Nausea and Vomiting (MK-0517-031)

Chemotherapy-Induced Nausea and Vomiting (CINV)
Qilu Hospital of Shandong University

Not yet recruiting

Antiemetic Prophylaxis With Fosaprepitant and Ondansetron in Patients Undergoing Thoracic Surgery

Thoracic Diseases | Postoperative Nausea and Vomiting | Anesthesia Complication
Merck Sharp & Dohme LLC

Completed

A Study of Aprepitant (MK-0869) in Pediatric Participants Undergoing Surgery (MK-0869-148)

Postoperative Nausea and Vomiting

United States, Brazil, Mexico, Spain, Turkey
Drexel University
Merck Sharp & Dohme LLC

Completed

Comparison of Aprepitant Versus Aprepitant and Transdermal Scopolamine for Preventing Postoperative Nausea and Vomiting

Nausea | Vomiting

United States
Gateway Institute for Brain Research

Recruiting

Intranasal Insulin and Glutathione as an Add-On Therapy in Parkinson's Disease (NOSE-PD)

Parkinson Disease

United States
Zhuhai Beihai Biotech Co., Ltd

Not yet recruiting

An Relative Bioavailability Study of BH006 for Injection in Healthy Subjects

Bioavailability
University of Aarhus

Completed

Effect of Obeticholic Acid on Transport of Bile Acids in PBC Examined by 11C-cholyl-sarcosine PET/CT

Primary Biliary Cirrhosis

Denmark
Chinese PLA General Hospital

Unknown

Cell Therapy in Patients With Chronic Ischemic Heart Disease Undergoing Cardiac Surgery

Left Ventricular Dysfunction | Chronic Myocardial Ischemia | Old Myocardial Infarction

China
Sinocelltech Ltd.

Unknown

SCT-I10A Plus Standard Chemotherapy in First-line Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma

China
NextCell Pharma Ab

Completed

Wharton´s Jelly Derived Mesenchymal Stromal Cell Treatment of Adult Patients Diagnosed With Type I Diabetes

Type1 Diabetes Mellitus

Sweden

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