Search clinical trials for: BKM120 temozolomide

Total 1033 results

Duke University
Genentech, Inc.; Schering-Plough

Completed

Avastin in Combination With Temozolomide for Unresectable or Multifocal GBMs and Gliosarcomas

Glioblastoma | Gliosarcoma

United States
Northwell Health
Feinstein Institute for Medical Research; Hofstra North Shore

Completed

Super-Selective Intraarterial Cerebral Infusion Of Temozolomide (Temodar) For Treatment Of Newly Diagnosed GBM And AA

Glioblastoma Multiforme | Anaplastic Astrocytoma

United States
Ipsen

Completed

Combination of Lanreotide Autogel 120mg and Temozolomide in Progressive GEP-NET (SONNET)

Gastroenteropancreatic Neuroendocrine Tumors

Germany, Austria
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Completed

Talabostat Combined With Temozolomide or Carboplatin in Treating Young Patients With Relapsed or Refractory Brain Tumors or Other Solid Tumors

Sarcoma | Kidney Cancer | Unspecified Childhood Solid Tumor, Protocol Specific | Ovarian Cancer | Brain and Central Nervous System Tumors | Neuroblastoma | Liver Cancer | Childhood Germ Cell Tumor

United States
Dana-Farber Cancer Institute
Merck Sharp & Dohme LLC; National Institutes of Health (NIH); Accelerate Brain... and other collaborators

Recruiting

Personalized NeoAntigen Cancer Vaccine w RT Plus Pembrolizumab for Patients With Newly Diagnosed GBM

Glioblastoma

United States
Cancer Institute and Hospital, Chinese Academy...

Not yet recruiting

An Open, Single-center Clinical Study of Surufatinib Combined With Temozolomide and S-1 in the First-line Treatment of Advanced Neuroendocrine Tumors

Neuroendocrine Tumors

China
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Gefitinib Plus Temozolomide in Treating Patients With Malignant Primary Glioma

Brain and Central Nervous System Tumors

United States
US Oncology Research
Novartis Pharmaceuticals

Completed

STAR Cape+BKM120 MBC With Brain Met

Breast Cancer | Metastatic Breast Cancer | Brain Metastases

United States
University of California, San Francisco
Novartis

Completed

BKM120 Combined With Vemurafenib (PLX4032) in BRAFV600E/K Mutant Advanced Melanoma

BRAF Mutant Metastatic Melanoma

United States
The Cleveland Clinic
National Cancer Institute (NCI)

Completed

Docetaxel and Temozolomide in Treating Patients With Metastatic Cancer

Unspecified Adult Solid Tumor, Protocol Specific

United States
Tel-Aviv Sourasky Medical Center
Radiation Therapy Oncology Group

Unknown

Comparison Study of WBRT and SRS Alone Versus With Temozolomide or Erlotinib in Patients With Brain Metastases of NSCLC

Carcinoma, Non-Small-Cell Lung | Neoplasm Metastasis

Israel
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

PI3K Inhibitor BKM120, Carboplatin, and Pemetrexed Disodium in Treating Patients With Stage IV Non-Small Cell Lung Cancer

Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer

United States
Yonggao Mou
The First Affiliated Hospital of Nanchang University

Recruiting

Anlotinib Combined With Dose-dense Temozolomide for the First Recurrent or Progressive Glioblastoma After STUPP Regimen

Glioblastoma

China
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Active, not recruiting

Temozolomide With or Without Capecitabine in Treating Patients With Advanced Pancreatic Neuroendocrine Tumors

Gastrinoma | Glucagonoma | Insulinoma | Pancreatic Polypeptide Tumor | Recurrent Islet Cell Carcinoma | Somatostatinoma | Islet Cell Carcinoma

United States
Canadian Cancer Trials Group
European Organisation for Research and Treatment of Cancer - EORTC; Trans Tasman...

Completed

Radiation Therapy With or Without Temozolomide in Treating Older Patients With Newly Diagnosed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

Canada, Germany, Japan, Netherlands
Asan Medical Center

Completed

TEMCAP in Grade 3 and Low Ki-67 Gastroenteropancreatic Neuroendocrine Tumors

Neuroendocrine Tumors | Neuroendocrine Carcinoma | Capecitabine | Temozolomide

Korea, Republic of
Ipsen

Completed

Efficacy and Safety of Lanreotide Autogel (ATG) in Combination With Temozolomide in Subjects With Thoracic Neuroendocrine Tumors. (ATLANT)

Neuroendocrine Tumours

Italy
Fuzhou General Hospital

Unknown

Temozolomide Plus Anti-angiogenesis Drugs and Radiotherapy as a Treatment for Glioblastoma

Glioblastoma

China
Patrick Y. Wen, MD
Memorial Sloan Kettering Cancer Center; Massachusetts General Hospital; Dana-Farber... and other collaborators

Completed

Zactima With Temodar During Radiation Treatment for Newly Diagnosed Stage IV Brain Tumors (Zactima)

Glioblastoma Multiforme | Gliosarcoma

United States
Vical

Completed

A Phase 3 Pivotal Trial Comparing Allovectin-7® Alone vs Chemotherapy Alone in Patients With Stage 3 or Stage 4 Melanoma

Metastatic Melanoma

United States, Belgium, Brazil, Canada, France, Germany, Israel, Italy, Netherlands, Poland, Russian Federation, Spain, Switzerland, Turkey
Jethro Hu

Active, not recruiting

Ketogenic Diet in Combination With Standard-of-care Radiation and Temozolomide for Patients With Glioblastoma

Glioblastoma | GBM

United States
National Cancer Institute (NCI)

Completed

O6-Benzylguanine and Temozolomide in Treating Young Patients With Recurrent or Progressive Gliomas or Brain Stem Tumors

Brain and Central Nervous System Tumors

United States
Northwestern University
GlaxoSmithKline; National Comprehensive Cancer Network; Robert H. Lurie Cancer...

Completed

Temozolomide and Pazopanib Hydrochloride in Treating Patients With Advanced Pancreatic Neuroendocrine Tumors That Cannot Be Removed By Surgery

Recurrent Islet Cell Carcinoma | Pancreatic Alpha Cell Carcinoma | Pancreatic Beta Islet Cell Carcinoma | Pancreatic Delta Cell Carcinoma | Pancreatic G-cell Carcinoma

United States
MetVital, Inc.

Unknown

Trial of AEO in New Glioblastoma (GBM) (AEO)

Glioblastoma Multiforme
Merck Sharp & Dohme LLC
AESCA Pharma GmbH

Terminated

Safety and Tolerability of Low-Dose Temozolomide During Whole Brain Radiation in Patients With Cerebral Metastases From Non-Small-Cell Lung Cancer (Study P04071)(TERMINATED)

Carcinoma, Non-Small-Cell Lung
National Cancer Institute (NCI)

Completed

Temozolomide and O6-benzylguanine in Treating Children With Solid Tumors

Sarcoma | Kidney Cancer | Unspecified Childhood Solid Tumor, Protocol Specific | Ovarian Cancer | Brain and Central Nervous System Tumors | Neuroblastoma | Liver Cancer | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

United States
Myrexis Inc.

Completed

Verubulin, Radiation Therapy, and Temozolomide to Treat Patients With Newly Diagnosed Glioblastoma Multiforme

Glioblastoma Multiforme

United States
Novartis Pharmaceuticals

Terminated

Study of Efficacy and Safety of Buparlisib (BKM120) Plus Paclitaxel Versus Placebo Plus Paclitaxel in Recurrent or Metastatic Head and Neck Cancer Previously Pre-treated With a Platinum Therapy

Head and Neck Squamous Cell Carcinoma

Germany, United Kingdom, United States, Spain, Italy, Canada, Poland, Russian Federation, Switzerland, Thailand, Korea, Republic of, Hungary, Ireland, Australia, Taiwan, France, India, Japan
The Affiliated Hospital of Qingdao University

Not yet recruiting

Iodine-125 Brachytherapy Together With Chemotherapy in Patients With Newly Diagnosed Glioblastoma (IBCNG)

Glioblastoma
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma

Brain and Central Nervous System Tumors | Neurotoxicity

United States
Yale University

Completed

TMZ + Olaparib for MGMT Hypermethylated Colorectal Cancer

Colorectal Cancer

United States
Peking University

Unknown

Study to Compare Capecitabine Combined With Dacarbazine(CAPDTIC) Versus Capecitabine Combined Temozolomide(CAPTEM) in Advanced and Metastatic Gastrointestinal Pancreatic and Esophageal Neuroendocrine Tumor

Neuroendocrine Tumors

China
Jiangsu Healthy Life Innovation Medical Technology...

Not yet recruiting

TTField in Combination With TMZ and Tislelizumab in The Treatment of Newly Diagnosed Glioblastoma.

Glioblastoma Multiforme
Oblato, Inc.

Active, not recruiting

Open-label Study Investigating of OKN-007 Combined With Temozolomide in Patients With Recurrent Glioblastoma

Recurrent Malignant Glioma | Brain Glioblastoma

United States
Memorial Sloan Kettering Cancer Center
Bristol-Myers Squibb

Active, not recruiting

Temozolomide, Cisplatin, and Nivolumab in People With Colorectal Cancer

Colorectal Adenocarcinoma

United States
Ohio State University Comprehensive Cancer Center

Completed

Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic Astrocytoma

Glioblastoma Multiforme/Anaplastic Astrocytoma

United States
Duke University
National Cancer Institute (NCI)

Completed

Temozolomide and O6-benzylguanine in Treating Patients With Newly Diagnosed, Recurrent, or Progressive Anaplastic Glioma

Brain and Central Nervous System Tumors

United States
Swiss Group for Clinical Cancer Research

Completed

Radiation Therapy Combined With Either Gefitinib or Temozolomide in Pats With NSCLC and Brain Metastases

Lung Cancer | Metastatic Cancer

Switzerland
INSYS Therapeutics Inc

Completed

IL13-PE38QQR Infusion After Tumor Resection, Followed by Radiation Therapy With or Without Temozolomide in Patients With Newly Diagnosed Malignant Glioma

Glioblastoma Multiforme | Oligoastrocytoma | Anaplastic Astrocytoma

United States
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Temozolomide in Association With Topotecan in Refractory or Relapsed Malignant Tumors in Children and Adolescents

Malignant Tumors | Refractory Tumors

France
Geisinger Clinic

Recruiting

Neoadjuvant Chemoradiation for Resectable Glioblastoma (NeoGlio)

Glioblastoma | High Grade Glioma | Surgery

United States
SCRI Development Innovations, LLC
Novartis

Completed

Trial of Erlotinib and BKM120 in Patients With Advanced Non Small Cell Lung Cancer Previously Sensitive to Erlotinib

Non Small Cell Lung Cancer

United States
Novartis Pharmaceuticals

Terminated

Safety and Efficacy of Buparlisib (BKM120) in Patients With Untreated Squamous Non-small Cell Lung Cancer (BASALT-2)

Non-Small Cell Lunch Cancer

Italy, United States, Germany, Spain, Canada
National Cancer Institute (NCI)

Terminated

O(6)-Benzylguanine and Temozolomide in Treating Patients With Glioblastoma Multiforme That Did Not Respond to Previous Temozolomide and Radiation Therapy

Brain and Central Nervous System Tumors

United States
Columbia University
Celgene Corporation; Schering-Plough

Unknown

Phase I Dose-Escalation Study Of Azacitidine In Combination With Temozolomide

Soft Tissue Sarcoma | Mesothelioma

United States
AHS Cancer Control Alberta

Not yet recruiting

Temozolomide Monotherapy or in Combination With Olaparib in Patients With Triple Negative Breast Cancer (TNBC)

Breast Cancer Triple Negative

Canada
Asan Medical Center

Completed

Preoperative CRT With Capecitabine ± Temozolomide in Patients With LARC

Advanced Rectal Cancer

Korea, Republic of
Haukeland University Hospital
Ullevaal University Hospital; Aarhus University Hospital; Rigshospitalet, Denmark and other collaborators

Completed

Everolimus and Temozolomide in Advanced Gastroenteropancreatic Neuroendocrine Carcinoma (G3)

Neuroendocrine Carcinoma

Norway
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Temozolomide Plus Irinotecan in Treating Patients With Recurrent Malignant Glioma

Brain and Central Nervous System Tumors

United States
Sun Yat-sen University
Fifth Affiliated Hospital, Sun Yat-Sen University

Unknown

A Clinical Trial on Whole-brain Radiotherapy With Temozolomide Concurrent Chemotherapy or Avoidance of Hippocampus for Patients of Brain Metastases

Brain Metastasis | Radiation Therapy Complication

China

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