Search clinical trials for: Bedaquiline (B)

Total 6968 results

Janssen Research & Development, LLC

Completed

A Study of Bedaquiline 100 Milligram (mg) Tablets Administered as Different Test Formulations Compared to the Commercial Tablet Formulation (F001) in Healthy Adult Participants

Healthy

Belgium
Otsuka Pharmaceutical Development & Commercialization...
Bill and Melinda Gates Foundation

Active, not recruiting

Safety and Efficacy Evaluation of 4-month Regimen of OPC-167832, Delamanid and Bedaquiline in Participants With Drug-Susceptible Pulmonary TB

Pulmonary TB

South Africa
International Maternal Pediatric Adolescent AIDS...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

TASK-002: Bioequivalence of Bedaquiline 400mg Administered in Crushed Form Compared to Tablet Form in Healthy Male and Female Adults Under Fed Conditions (BDQ Crush Study)

Tuberculosis

South Africa
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Efficacy and Safety of Bedaquiline (TMC207) in Participants With Multibacillary Leprosy

Leprosy, Multibacillary

Brazil
Janssen Research & Development, LLC

Recruiting

Pharmacokinetic Study to Evaluate Anti-mycobacterial Activity of TMC207 in Combination With Background Regimen (BR) of Multidrug Resistant Tuberculosis (MDR-TB) Medications for Treatment of Children/Adolescents Pulmonary MDR-TB

Multidrug-Resistant Tuberculosis

Mozambique, Philippines, Russian Federation, South Africa, Uganda, Ukraine
Institute of Tropical Medicine, Belgium
Damien Foundation

Completed

Bedaquiline Enhanced Post ExpOsure Prophylaxis for Leprosy (Phase 2) (BE-PEOPLE P2)

Leprosy

Comoros
Janssen Pharmaceutical K.K.

Completed

An Exploratory Study of TMC207 in Japanese Participants With Pulmonary Multi-Drug Resistant Tuberculosis (MDR-TB)

Tuberculosis, Multidrug-Resistant

Japan
University of Texas Southwestern Medical Center

Completed

Rilonacept in Diabetes Mellitus Type 1: Safety Study (RID-A)

Type 1 Diabetes Mellitus

United States
Global Alliance for TB Drug Development

Completed

A Phase 3 Study Assessing the Safety and Efficacy of Bedaquiline Plus PA-824 Plus Linezolid in Subjects With Drug Resistant Pulmonary Tuberculosis

Pulmonary Tuberculosis

South Africa
Shanghai Jiatan Pharmatech Co., Ltd

Enrolling by invitation

Sudapyridine (WX-081) in RR/MDR/XDR-tuberculosis Patients (WISH)

Rifampicin-resistant Tuberculosis

China
Janssen Infectious Diseases BVBA

Approved for marketing

Early Access of TMC207 in Patients With Extensively Drug Resistant or Pre-XDR Pulmonary Tuberculosis

Tuberculosis

Russian Federation, Lithuania
Tibotec BVBA

Completed

TMC207-C202: Study to Evaluate Bactericidal Activity of Multiple Oral Doses of TMC207 in Subjects With Sputum-Smear Positive Tuberculosis

Tuberculosis
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Active, not recruiting

Evaluating the Pharmacokinetics, Safety, and Tolerability of Bedaquiline in Infants, Children, and Adolescents With Multidrug-Resistant Tuberculosis, Living With or Without HIV

HIV | Tuberculosis

Haiti, India, South Africa
Tibotec BVBA

Completed

TMC207-TiDP13-C110: Interaction Study With Lopinavir/Ritonavir in Healthy Volunteer

HIV | Tuberculosis
National Institute of Allergy and Infectious Diseases...

Recruiting

Linezolid Dosing Strategies in Drug-Resistant TB

Tuberculosis | Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant

Brazil, India, Kenya, Philippines, South Africa, Zimbabwe, Thailand, Haiti, Peru, Botswana
Global Alliance for TB Drug Development

Completed

Various Doses and Durations of Linezolid Plus Bedaquiline & Pretomanid in Participants With Drug Resistant Tuberculosis (ZeNix)

Tuberculosis | Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Extensively Drug-Resistant Tuberculosis | Tuberculosis, MDR | XDR-TB | Pre-XDR-TB

South Africa, Russian Federation, Georgia, Moldova, Republic of
LigaChem Biosciences, Inc.
Radboud University Medical Center; University of California, San Francisco; Ludwig-Maximilians...

Completed

PanACEA DElpazolid Dose-finding and COmbination DEvelopment (DECODE) (DECODE)

Pulmonary Tuberculosis | Infections and Infestations

Tanzania, South Africa
Janssen Infectious Diseases BVBA

Withdrawn

A Study to Evaluate the Efficacy and Safety of TMC207 in Patients With Pulmonary Infection With Multi-drug Resistant Mycobacterium Tuberculosis

Multi-drug Resistant Tuberculosis

China, Ukraine, Taiwan, Korea, Republic of, Peru, Brazil, Estonia, Latvia, Philippines, Russian Federation, South Africa, Thailand, Turkey, Georgia, Mexico, Cambodia, Ethiopia
Global Alliance for TB Drug Development

Completed

Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis (TMC207-CL001)

Pulmonary Tuberculosis

South Africa
Janssen Infectious Diseases BVBA

Completed

To Evaluate the Safety, Tolerability, and Efficacy of TMC207 as Part of an Individualized Multi-drug Resistant Tuberculosis (MDR-TB) Treatment Regimen in Participants With Sputum Smear-positive Pulmonary MDR-TB.

Tuberculosis

China, Ukraine, Korea, Republic of, Peru, Estonia, Kenya, Latvia, Philippines, Russian Federation, South Africa, Thailand, Turkey
Bill & Melinda Gates Medical Research Institute
Global Alliance for TB Drug Development; Janssen Pharmaceutica; Otsuka Pharmaceutical...

Recruiting

Efficacy and Safety Evaluation of Two to Four Months of Treatment With the Combination Regimens of DBOS and PBOS in Adults With Pulmonary Tuberculosis

Pulmonary Tuberculosis

South Africa, Philippines
GlaxoSmithKline
Click-TB Consortium

Recruiting

Early Bactericidal Activity, Safety & Tolerability of Oral GSK3036656 in a Dual Combination With Novel and Established Antitubercular Agents, or Standard of Care in Adults With Rifampicin Susceptible Pulmonary Tuberculosis

Tuberculosis

South Africa
Shanghai Jiatan Pharmatech Co., Ltd

Completed

Evaluation of Early Bactericidal Activity and Safety in Pulmonary Tuberculosis With WX-081 (WX-081)

Pulmonary Tuberculosis

China
Tibotec BVBA

Completed

A Study of TMC207 in Patients With Moderately Impaired Hepatic Function

Moderate Hepatic Impairment
Médecins Sans Frontières, France
Harvard Medical School (HMS and HSDM); Institute of Tropical Medicine, Belgium and other collaborators

Active, not recruiting

Evaluating Newly Approved Drugs in Combination Regimens for Multidrug-Resistant TB With Fluoroquinolone Resistance (endTB-Q) (endTB-Q)

Bacterial Infections | Gram-Positive Bacterial Infections | Tuberculosis | Tuberculosis, Multidrug-Resistant | Pulmonary Tuberculoses | Mycobacterial Infections

Vietnam, Pakistan, India, Kazakhstan, Lesotho, Peru
Beijing Chest Hospital

Recruiting

Randomized Controlled Multi-center Short Course Treatment for Rifampicin Resistant Tuberculosis

Tuberculosis

China
Janssen Infectious Diseases BVBA

Completed

TMC207-TiDP13-C208: Anti-bacterial Activity, Safety, and Tolerability of TMC207 in Participants With Multi-drug Resistant Mycobacterium Tuberculosis (MDR-TB).

Tuberculosis

South Africa, Peru, Latvia, Philippines, Russian Federation, Thailand, Brazil, India
Global Alliance for TB Drug Development

Completed

PK Interaction Between Rifapentine or Rifampicin and a Single Dose of TMC207 in Healthy Subjects (TMC207-CL002)

Tuberculosis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Rilonacept to Improve Artery Function in Patients With Atherosclerosis

Coronary Artery Disease | Inflammation | Atherosclerosis | Endothelial Dysfunction

United States
BioNTech SE

Completed

Safety and Immunogenicity of RNA-based Vaccines Against SARS-CoV-2 Variants in Healthy Participants

COVID-19 | SARS-CoV2 Infection | SARS-CoV-2 Acute Respiratory Disease | SARS (Disease)

United States, Germany, Turkey, South Africa
National Institute of Allergy and Infectious Diseases...
Dynavax Technologies Corporation

Active, not recruiting

B-Enhancement of HBV Vaccination in Persons Living With HIV (BEe-HIVe): Evaluation of HEPLISAV-B (BEe-HIVe)

HIV Infection | Hepatitis B

United States, Haiti, Botswana, Philippines, Thailand, Brazil, Kenya, Malawi, South Africa, Uganda, Vietnam
Tuberculosis Research Centre, India
International Union Against Tuberculosis and Lung Diseases; Sarvodaya Charitable... and other collaborators

Active, not recruiting

Modified BPaL Regimen for Managing Pre-XDR TB and MDR (TI/NR) TB in India (mBPaL)

Pre-Extensively Drug-Resistant Pulmonary TB | Treatment Intolerant Multidrug-Resistant Pulmonary TB | Non-responsive Multidrug-Resistant Pulmonary TB

India
ChemoCentryx
Medpace, Inc.

Completed

A Study of CCX140-B in Subjects With FSGS

Focal Segmental Glomerulosclerosis | FSGS | Glomerulosclerosis

United States, France, Italy, Australia, United Kingdom, Canada, New Zealand, Poland
Pfizer

Completed

A Bioequivalence (BE) Study Comparing The Commericializable And Clinical Formulations Of PF-00299804

Healthy Volunteers

Belgium
Indiana University
Alcon Research

Completed

On-Eye Optical Quality of Lotrafilcon B Lenses Over 12 Hours

Myopia | Hyperopia

United States
Marya Strand, MD

Completed

Comparative Effectiveness Study of Bubble CPAP Devices in the NICU

Respiratory Distress Syndrome

United States
Soroka University Medical Center

Completed

Hepatitis B Vaccine in Patients With Inflammatory Bowel Disease (HBV VIP)

Inflammatory Bowel Disease

Israel
Institute of Tropical Medicine, Belgium

Recruiting

Bedaquiline Enhanced Post ExpOsure Prophylaxis for Leprosy (BE-PEOPLE P3)

Leprosy

Comoros
Epstein, Arthur B., OD, FAAO
Alcon Research

Completed

Study of the Presence and Extent of Corneal Disturbance Associated With B+L Biotrue MPS Used With B+L PureVision Lenses

Keratitis

United States
Wright State University

Recruiting

DNA Repair Activity in the Skin of Day and Night Shift Workers

Skin Cancer

United States
S.LAB (SOLOWAYS)
Center of New Medical Technologies

Recruiting

Evaluation of a Genetically Determined Personalized Approach in Prescribing Biologically Active Substances in Patients With Elevated Blood Homocysteine Levels. (PERBIO-HC)

Hyperhomocysteinemia

Russian Federation
Novo Nordisk A/S

Completed

A Research Study of How a New Medicine NNC0365-3769 (Mim8) Works in the Body of Healthy People

Healthy Volunteers - Haemophilia A

Germany
Eli Lilly and Company

Completed

A Study of LY3143753 and LY3185643 in Healthy Participants

Healthy

United Kingdom
Shaare Zedek Medical Center

Unknown

Comparison of Engerix B Vaccine Versus Sci-B-Vac Vaccine in Celiac Patients

Celiac Disease

Israel
Sonova AG

Completed

Quality Control of CE-Certified Phonak Hearing Aids - 2018_07

Hearing Loss, Sensorineural

Switzerland
PepsiCo Global R&D

Completed

Investigation of How Morning Nutrition Influences Cognitive Performance

Cognitive Performance

United States
Coopervision, Inc.

Active, not recruiting

Clinical Evaluation of Proclear Toric and Biofinity Toric

Astigmatism

Canada
Coopervision, Inc.
CORE

Active, not recruiting

Performance Evaluation of Reusable Contact Lenses When Worn For One Month By Habitual Soft Contact Lens Wearers

Myopia | Hyperopia

Canada
Tel-Aviv Sourasky Medical Center

Unknown

Efficacy and Safety of Hepatitis B Vaccine in Chronic Kidney Disease Patients

Hepatitis B | Chronic Kidney Disease

Israel
Lesaffre International
NIZO Food Research

Completed

BSCU1 and Immune Function

General Population

Netherlands

Search clinical trials for: Bedaquiline (B)

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