Search clinical trials for: Best suportive care (BSC)

Total 834 results

Ipsen

Not yet recruiting

Effects of Maintenance Cabozantinib+BSC Versus BSC in Children and AYA With Osteosarcoma (CabOSTar)

Osteosarcoma | Osteosarcoma in Children | Osteosarcoma in Adolescents and Young Adults
Janssen Research & Development, LLC

Terminated

A Study Comparing Siltuximab Plus Best Supportive Care to Placebo Plus Best Supportive Care in Anemic Patients With International Prognostic Scoring System Low- or Intermediate-1-Risk Myelodysplastic Syndrome

Myelodysplastic Syndrome

United States, Belgium, Spain, Australia, Sweden, Netherlands, Russian Federation
InflaRx GmbH

Completed

Randomized, Controlled Study of IFX-1 in Patients With Severe COVID-19 Pneumonia (PANAMO)

Severe COVID-19 Pneumonia

Belgium, Brazil, France, Germany, Mexico, Netherlands, Peru, Russian Federation, South Africa
Bayer

Completed

Patients With Metastatic Colorectal Cancer Treated With Regorafenib or Placebo After Failure of Standard Therapy

Metastatic Colorectal Cancer

Belgium, Italy, Spain, Canada, Japan, Czech Republic, United States, Australia, France, Hungary, China, Germany, Israel, Netherlands, Turkey, Portugal, Brazil, Switzerland, Argentina
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Efficacy and Safety of CNTO328 Plus Best Supportive Care in Multicentric Castleman's Disease

Multicentric Castleman's Disease

United States, Canada, France, United Kingdom, China, Germany, Taiwan, Spain, Belgium, Israel, India, Korea, Republic of, Netherlands, Singapore, Brazil, Russian Federation, New Zealand, Hungary, Norway, Australia, Egypt, Hong Kong, Malaysi...
Fuzhou General Hospital

Recruiting

Defining COVID-19 Infection Severity on Presentation to Hospital

Infections | COVID-19 | Morality | Death, Assisted

China
Celgene
Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway...

Completed

A Study to Determine the Efficacy and Safety of Luspatercept in Adults With Non Transfusion Dependent Beta (β)-Thalassemia (BEYOND)

Thalassemia

United States, Greece, Italy, Lebanon, Thailand, United Kingdom
Biocon Limited

Completed

Efficacy and Safety of Itolizumab in COVID-19 Complications

Covid19 | Acute Respiratory Distress Syndrome | Cytokine Release Syndrome

India
Amgen

Completed

Comparison of Survival Benefit of Panitumumab With Supportive Care to Best Supportive Care Alone in Patients With Metastatic Colorectal Cancer

Metastatic Colorectal Cancer

Romania, Canada, Korea, Republic of, Philippines, Lithuania, Serbia, Latvia, Estonia, Greece, India, China, Croatia, Mexico, Malaysia, Chile, Brazil
Baylx Inc.

Not yet recruiting

Use of hUC-MSC Product (BX-U001) for the Treatment of COVID-19 With ARDS

COVID-19 | Acute Respiratory Distress Syndrome | ARDS
Sun Yat-sen University
Affiliated Cancer Hospital of Shantou University Medical College; Affiliated...

Completed

Maintenance Capecitabine Plus Best Supportive Care Versus Best Supportive Care for Metastatic Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma

China
Poniard Pharmaceuticals

Unknown

Study of Picoplatin Efficacy After Relapse (SPEAR)

Small Cell Lung Cancer

India, Russian Federation, Argentina, Belarus, Bosnia and Herzegovina, Bulgaria, Chile, Croatia, Hungary, Latvia, Montenegro, Poland, Romania, Serbia, Ukraine
Duke University
University of Colorado, Denver; Northwestern University; University of California... and other collaborators

Completed

PCRC Best Supportive Care (PCRC BSC) (PCRC BSC)

Feasibility of Best Supportive Care Delivery
Novartis Pharmaceuticals

Completed

Everolimus Plus Best Supportive Care vs Placebo Plus Best Supportive Care in the Treatment of Patients With Advanced Neuroendocrine Tumors (GI or Lung Origin) (RADIANT-4)

Neuroendocrine Tumors | Advanced NET of GI Origin | Advanced NET of Lung Origin

United States, Colombia, Italy, Taiwan, United Kingdom, Belgium, Czechia, Germany, Japan, Saudi Arabia, Canada, Netherlands, Spain, Korea, Republic of, Lebanon, Austria, China, Greece, South Africa, Thailand, Hungary, Turkey, Poland, ... and more
Boehringer Ingelheim

Terminated

Phase I/II Trial to Investigate BI 836858 in Myelodysplastic Syndromes

Myelodysplastic Syndromes

United States, Germany
Novartis Pharmaceuticals

Completed

Safety and Efficacy of RAD001 (Everolimus) Monotherapy Plus Best Supportive Care in Patients With Advanced Gastric Cancer (AGC) (GRANITE-1)

Advanced Gastric Cancer

China, United States, Belgium, France, Taiwan, United Kingdom, Canada, Spain, Italy, Australia, Russian Federation, Thailand, Korea, Republic of, Israel, Germany, Peru, Argentina, Japan, Hong Kong, New Zealand, Mexico, Netherlands
Norwegian University of Science and Technology

Completed

Physical Activity and Functioning in Palliative Cancer Patients - a Clinical Randomised Trial

Cancer

Norway
Hackensack Meridian Health
United States Department of Defense

Terminated

Convalescent Plasma as Treatment for Subjects With Early COVID-19 Infection

COVID-19

United States
NCIC Clinical Trials Group
Sumitomo Pharma Oncology, Inc.

Completed

BBI608 and Best Supportive Care vs Placebo and Best Supportive Care in Pretreated Advanced Colorectal Carcinoma

Colorectal Carcinoma

Canada, Australia, Japan
Hospital Clinico Universitario de Santiago
Fundación Ramón Domínguez

Terminated

Phase II-b Randomized Clinical Trial of Cabazitaxel in Metastatic Colorectal Cancer Resistant to Standard Treatment (COMETA)

Colorectal Cancer

Spain
Ohio State University Comprehensive Cancer Center

Recruiting

Weighted Blanket Use to Reduce Anxiety in Oncology Patients

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm

United States
Genzyme, a Sanofi Company

Completed

Phase II Study of Best Support Care (BSC) Plus ZD6474(Vandetanib) in Patients With Inoperable Hepatocellular Carcinoma (HCC)

Carcinoma, Hepatocellular

Taiwan
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Active, not recruiting

Simplified Patient Care Strategy in Decreasing Early Death in Patients With Acute Promyelocytic Leukemia

Acute Promyelocytic Leukemia With PML-RARA | t(15;17)

United States, Puerto Rico
Morphotek

Terminated

Morphotek Investigation in Colorectal Cancer: Research of MORAb-004 (MICRO)

Metastatic Colorectal Cancer | Colorectal Cancer

United States
Cambridge University Hospitals NHS Foundation Trust
King's College London; University of Cambridge

Unknown

Trial of a Breathlessness Intervention Service for Intractable Breathlessness

Dyspnea

United Kingdom
Jasper Gerritsen
Massachusetts General Hospital; Universitaire Ziekenhuizen KU Leuven; University... and other collaborators

Recruiting

The PALSUR-study: Palliative Care Versus Surgery in High-grade Glioma Patients (ENCRAM 2203) (PALSUR)

Glioblastoma | Glioblastoma Multiforme | Glioblastoma, IDH-wildtype | Glioblastoma Multiforme, Adult

United States, Belgium, Switzerland, Germany, Netherlands
Stanford University

Active, not recruiting

Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer

Acute Myeloid Leukemia | Stage IIIA Non-Small Cell Lung Cancer | Stage IIIB Non-Small Cell Lung Cancer | Progressive Disease | Myelodysplastic Syndrome | Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer and other conditions

United States
Cambridge University Hospitals NHS Foundation Trust
King's College London

Completed

Pilot Randomized Controlled Trial of a Breathlessness Intervention Service for Chronic Obstructive Pulmonary Disease (BIS-PhIInm)

Dyspnea

United Kingdom
Dr Anjali Zarkar
Sanofi

Completed

Treatment of Locally Advanced or Metastatic Transitional Cell Carcinoma With Cabazitaxel (CabB1)

Transitional Cell Carcinoma

United Kingdom
Capital Medical University

Completed

Study of S-1 Plus DC-CIK for Patients With Unresectable Locally Advanced Pancreatic Cancer

Pancreatic Cancer

China
Bristol-Myers Squibb

Completed

An Efficacy Study in Gastric and Gastroesophageal Junction Cancer Comparing Ipilimumab Versus Standard of Care Immediately Following First Line Chemotherapy

Locally Advanced (Unresectable) or Metastatic Adenocarcinoma of the Gastric and Gastro-esophageal Junction

France, Poland, Russian Federation, Taiwan, United States, Hong Kong, Spain, Germany, Italy, Japan, Korea, Republic of, Singapore
Simon Toh
University of Portsmouth

Unknown

The Best Care for Abdominal Emergencies Study (BCAE)

Peritonitis | Acute Abdomen | Bowel Obstruction | Bowel; Ischemic, Acute | Bowel Perforated

United Kingdom
Odense University Hospital
Baxter Healthcare Corporation; Danish Cancer Society; Region of Southern Denmark and other collaborators

Terminated

Study of Parenteral Nutrition to Patients With Gastrointestinal Cancer

Quality of Life | Body Composition, Beneficial | Gastrointestinal Cancer | Dietary Modification | Cancer Cachexia

Denmark
Icahn School of Medicine at Mount Sinai
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Informatics Framework for Pulmonary Rehabilitation (CHIEF-PR)

COPD

United States
People's Hospital of Guangxi

Unknown

Maintenance Therapy With Autologous Cytokine-induced Killer Cells for Small Cell Lung Cancer

Small Cell Lung Cancer

China
Centre Leon Berard

Recruiting

Efficacy of Regorafenib Combined With Best Supportive Care as Maintenance Treatment in High Grade Bone Sarcomas Patients (REGOMAIN)

Osteosarcoma | Bone Sarcoma

France
AbbVie

Active, not recruiting

A Study Evaluating Safety and Efficacy of Venetoclax in Combination With Azacitidine Versus Standard of Care After Allogeneic Stem Cell Transplantation (SCT) in Participants With Acute Myeloid Leukemia (AML) (VIALE-T)

Cancer | Acute Myeloid Leukemia (AML)

United States, Australia, Brazil, Canada, China, Czechia, France, Germany, Greece, Hungary, Israel, Italy, Japan, Korea, Republic of, Spain, Switzerland, Taiwan, United Kingdom
Merck Sharp & Dohme LLC

Active, not recruiting

Study of Pembrolizumab (MK-3475) or Placebo Given With Best Supportive Care in Asian Participants With Previously Treated Advanced Hepatocellular Carcinoma (MK-3475-394/KEYNOTE-394)

Carcinoma, Hepatocellular

Korea, Republic of, China, Hong Kong, Malaysia, Taiwan
Eli Lilly and Company

Completed

Study of IMC-1121B (Ramucirumab) With Best Supportive Care in Participants With Gastric Cancer and Adenocarcinoma

Adenocarcinoma | Gastric Cancer

United States, Canada, Brazil, Czechia, Egypt, Korea, Republic of, Lebanon, Poland, Russian Federation, Spain, Romania, United Kingdom, Australia, Croatia, Italy, Philippines, Thailand, Argentina, Bosnia and Herzegovina, Chile, ... and more
Sanofi

Completed

Tax First-line Chemotherapy With Different Doses and Then Maintenance Therapy (TFINE)

Lung Neoplasms

China
Onconova Therapeutics, Inc.

Terminated

Controlled Study of Rigosertib Versus Physician's Choice of Treatment in MDS Patients After Failure of an HMA (INSPIRE)

Myelodysplastic Syndrome | MDS | Refractory Anemia With Excess Blasts | RAEB

United States, Spain, Canada, France, Australia, Switzerland, Israel, Japan, Belgium, India, Ireland, United Kingdom, Croatia, Czechia, Poland, Estonia, Germany, Italy, Austria, Hungary, Russian Federation, Sweden
AB Science

Recruiting

Masitinib for the Treatment of Severe Mast Cell Activation Syndrome

Mast Cell Activation Syndrome

France, United States
Rigshospitalet, Denmark

Recruiting

Prognostic Factors for Survival in Patients With Cholangiocarcinoma

Cholangiocarcinoma

Denmark
Chemo Mouthpiece

Completed

A Trial Assessing Chemo Mouthpiece Device With Best Supportive Care for Symptoms of Chemotherapy-Induced Oral Mucositis

Oral Mucositis

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Telemedicine for Improvement of Care for Older Adults With Cancer in the Underserved Community, The GAIN-S Trial

Malignant Solid Neoplasm | Hematopoietic and Lymphoid System Neoplasm

United States
NewLink Genetics Corporation

Completed

A Phase 2 Study of CRLX101(NLG207) in Patients With Advanced Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer

Russian Federation, Ukraine
Stephanie Combs

Unknown

Evaluation of Repeated Whole Brain Radiotherapy Versus Best Supportive Care for Multiple Brain Metastases. (ERASER)

Brain Metastasases

Germany
Pierre Fabre Medicament
Bristol-Myers Squibb

Completed

Phase III Trial of Vinflunine Plus Best Supportive Care vs. Best Supportive Care in Patients With Transitional Cell Carcinoma (TCC) of the Urothelial Tract

Bladder Cancer | Bladder Neoplasms | Transitional Cell Carcinoma of the Urothelial Tract

Canada
Celgene

Completed

The Efficacy and Safety of Oral Azacitidine Plus Best Supportive Care Versus Placebo and Best Supportive Care in Subjects With Red Blood Cell (RBC) Transfusion-Dependent Anemia and Thrombocytopenia Due to International Prognostic Scoring System (IPSS) Low Risk Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndrome

United States, Australia, Canada, Czechia, France, Germany, Italy, Korea, Republic of, Mexico, Poland, Sweden, United Kingdom, Belgium, Brazil, Denmark, Finland, Greece, Israel, Netherlands, Norway, Portugal, Spain, Turkey
National Cancer Institute, Lithuania

Recruiting

Transanal Irrigation - Best Treatment Possibility for Low Anterior Resection Syndrome? Multicenter, Randomized Clinical Trial

Low Anterior Resection Syndrome

Lithuania

Search clinical trials for: Best suportive care (BSC)

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