Search clinical trials for: Beta-lactamase inhibitor

Total 68897 results

Assistance Publique - Hôpitaux de Paris

Completed

Pharmacodynamic Drug Interaction Between Warfarin and Amoxicillin-clavulanic Acid (INWARA)

Atrial Fibrillation | Pulmonary Embolism | Deep Venous Thrombosis | Oral Anticoagulation

France
All India Institute of Medical Sciences, New Delhi

Terminated

Early Stoppage Versus Continuation of Antimicrobial Therapy in Low Risk Pediatric Cancer Patients With Febrile Neutropenia, Before Recovery of Counts: -DALFEN Study (DALFEN)

Pediatric Cancer | Neutropenia, Febrile

India
Eskisehir Osmangazi University
Hacettepe University; Yuzuncu Yıl University; Goztepe Training and Research Hospital and other collaborators

Completed

Effect of Lactobacillus Reuteri DSM 17938 to Prevent Antibiotic-associated Diarrhea in Children (PEARL)

Antibiotic Associated Diarrhea

Turkey
Cubist Pharmaceuticals LLC

Completed

Plasma Pharmacokinetics (PK) & Lung Penetration of Ceftolozane/Tazobactam in Participants With Pneumonia (MK-7625A-007)

Pneumonia | Critically Ill
University Hospital, Toulouse

Recruiting

Short Infusion Versus Prolonged Infusion of Ceftolozane-tazobactam Among Patients With Ventilator Associated-pneumonia (CEFTOREA)

Ventilator-associated Pneumonia

France
Universitat Internacional de Catalunya
Hospital de Granollers

Completed

Study the Efficacy of Topical Antibiotherapy in the Prophylaxis of Incisional Surgical Infection in Colorectal Surgery (PROTOP)

Surgical Wound Infection | Postoperative Wound Infection | Postoperative Wound Infection Superficial Incisional | Preventive Therapy

Spain
Merck Sharp & Dohme LLC

Completed

Ceftolozane/Tazobactam (MK-7625A) Plus Metronidazole Versus Meropenem for Participants With Complicated Intra-abdominal Infection (MK-7625A-015) (7625ACNPhase3)

Complicated Intra-abdominal Infections

China
Rexahn Pharmaceuticals, Inc.

Completed

Efficacy Study of RX-10100 to Treat Erectile Dysfunction (ED)

Erectile Dysfunction (ED)

United States
University Hospital, Ghent
Imec; Research Foundation Flanders

Not yet recruiting

Validation of Betalactam ML Prediction Models - TDMAide (TDMAide)

Infections

Belgium
Merck Sharp & Dohme LLC

Completed

Ertapenem Sodium (MK-0826) Versus Piperacillin/Tazobactam Sodium for the Treatment of Diabetic Foot Infections in Chinese Adults (MK-0826-061)

Infection; Diabetic Foot
Centre Hospitalier Universitaire, Amiens

Completed

Place of Antibiotics in the Postoperative Acute Lithiasic Cholecystitis (ABCAL)

Acute Lithiasic Cholecystitis Grade I or II | Symptoms Lasting for Less Than 5 Days | Required Cholecystectomy | Preoperative Amoxicillin Clavulanic Acid for at Most 5 Days

France
Teva Pharmaceuticals USA

Completed

600 mg Amoxicillin/42.9 mg Clavulanate Postassium /5 mL Suspension Under Fasting Conditions

Healthy

Canada
Fundació Institut de Recerca de l'Hospital de la...

Recruiting

Fast Track Therapeutic Model in Acute Complicated Appendicitis in Pediatrics (FTAA)

Complicated Appendicitis | Laparoscopic Appendectomy | Periappendicular Abscess

Spain
GlaxoSmithKline

Completed

Bioequivalence Study of an Amoxicillin-Clavulanic

Infections, Respiratory Tract
Janssen Research & Development, LLC

Terminated

A Safety and Tolerability Study of Doripenem Compared With Cefepime in Hospitalized Children With Bacterial Pneumonia

Pneumonia, Bacterial | Pneumonia, Ventilator-Associated | Nosocomial Infection | Community-Acquired Infections

Poland, Ukraine, United States, Argentina, Colombia, Brazil, Panama, Lithuania, Mexico, Latvia
Universita degli Studi di Catania

Completed

Antibiotic Therapy is Not Necessary to Implant Totally Implantable Venous Access Devices: Randomized Prospective Study (TIVAD)

Infections
Cairo University

Unknown

Effect of Irrigation With Antibiotic-containing Solutions on Postoperative Pain and Intra-canal Bacteria

Necrotic Pulp

Egypt
Uppsala University
Karolinska Institutet; Oslo University Hospital; Göteborg University; New York... and other collaborators

Terminated

Randomized Evaluation of Beta Blocker and ACEI/ARB Treatment in MINOCA Patients - MINOCA-BAT (MINOCA-BAT)

Myocardial Infarction With Non-obstructive Coronary Arteries

Norway, Sweden, Australia, New Zealand, Spain
University of Chicago
Loyola University

Active, not recruiting

Collaborative Urological Prosthetics Investigation Directive Research Group (CUPID)

Erectile Dysfunction | Penile Prosthesis Infection

United States
Quanta Medical
Laboratoires Iprad-Vegebom

Terminated

A Multicentre, Randomized as a Double Blind Study, Triple Placebo, Comparative of the Efficacy and Safety of an Association Secnidazol-Ciprofloxacin Compared With Amoxicillin-Clavulanic Acid for the Treatment of Uncomplicated Episode of Diverticular Sigmoïditis Among Adults (DIVA)

Diverticular Sigmoïditis
Johnson & Johnson Pharmaceutical Research & Development...
PriCara, Unit of Ortho-McNeil, Inc.

Completed

A Study of the Effectiveness and Safety of High Dose, Short-course Levofloxacin in the Treatment of Acute Bacterial Exacerbation (Worsening) of Chronic Bronchitis.

Bronchitis | Chronic Bronchitis
Universitaire Ziekenhuizen KU Leuven

Unknown

Target Attainment and Pharmacokinetics of Antimicrobials in Non-critically Ill Surgery Patients (TAPAS) (TAPAS)

Surgery

Belgium
Instituto Nacional de Cancerologia de Mexico

Recruiting

Ceftolozane/Tazobactam vs. Piperacillin/Tazobactam for the Treatment of Bacteremia in Hemato-oncological Patients

Hematologic Neoplasms | Neutropenia

Mexico
Merck Sharp & Dohme LLC

Completed

MK-7625A Plus Metronidazole Versus Meropenem in Pediatric Participants With Complicated Intra-Abdominal Infection (cIAI) (MK-7625A-035)

Complicated Intra-Abdominal Infection

Brazil, Hungary, United States, Lithuania, Malaysia, Mexico, Romania, Russian Federation, South Africa, Spain, Turkey, Ukraine
University of Michigan

Completed

Optimal Care of Complicated Appendicitis

Appendicitis | Complicated Appendicitis | Perforated Appendicitis | Ruptured Appendicitis

United States
Komagome Hospital
Japan Agency for Medical Research and Development; Prism Pharma Co., Ltd.

Completed

An Open Label, Single Arm, Dose Escalation Phase 1 Trial of PRI-724 in Patients With HCV-induced Cirrhosis

Hepatitis C Virus-infected Cirrhosis

Japan
Komagome Hospital
Japan Agency for Medical Research and Development; Prism Pharma Co., Ltd.

Completed

A Follow-up Evaluation Study of PRI-724-1101

Hepatitis C Virus-infected Cirrhosis

Japan
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Completed

A Phase II Study of Faropenem in the Treatment of Adult Community-acquired Bacterial Pneumonia

Community Acquired Pneumonia

China
Centre Hospitalier Universitaire Vaudois
Unisanté Centre universitaire de médecine générale et santé publique; FORCE...

Not yet recruiting

Adjustment of Antibiotic Dosage in Pediatric Oncology Patients With Febrile Neutropenia and Augmented Renal Clearance (DAR-ARC)

Febrile Neutropenia

Switzerland
Hospital de Granollers

Completed

Prophylaxis of Surgical Wound Infection in Incisional Hernia Repair With Topical Antibiotics (PROTOP-PAR) ((PROTOP-PAR))

Postoperative Hernia

Spain
Loma Linda University

Completed

Oral Steroids in Chronic Rhinosinusitis Without Nasal Polyps

Sinusitis

United States
Solvay Pharmaceuticals

Completed

Interaction Study SLV337/Simvastatin

Type 2 Diabetes Mellitus

United Kingdom
Shandong University
The Second Hospital of Shandong University

Recruiting

Population Pharmacokinetics and Dosage Individualization of Antibiotics in Elderly Patients

Elderly Infection

China
AstraZeneca

Completed

Relative Bioavailability Study to Assess Two Solid Formulations Compared to an Oral Solution of AZD3293 in Healthy Male and Non-Fertile Female Subjects (BA)

Healthy Volunteers | Pharmacologic Action

United States
Merck Sharp & Dohme LLC

Completed

Safety, Tolerability, and Efficacy of MK-7655 (Relebactam) + Imipenem/Cilastatin Versus Imipenem/Cilastatin Alone for Treating Complicated Urinary Tract Infection (cUTI) (MK-7655-003)

Urinary Tract Infections | Pyelonephritis
Zealand University Hospital

Recruiting

Per Oral Versus Intravenous Postoperative Antibiotics After Surgery for Complicated Appendicitis. (PIPA)

Complicated Appendicitis

Denmark
Hospital Universitari de Bellvitge
Baxter Healthcare Corporation

Completed

Antibiotic Plasma Concentrations During Continuous Renal Replacement Therapy With a High Adsorption Membrane (oXiris®)

Sepsis | Acute Kidney Injury | Hemodiafiltration

Spain
Clatterbridge Centre for Oncology

Unknown

Early Hospital Discharge or Standard Inpatient Care in Cancer Patients Receiving Antibiotics for Febrile Neutropenia

Lymphoma | Small Intestine Cancer | Neutropenia | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Psychosocial Effects of Cancer and Its Treatment

United Kingdom
Centre Hospitalier Universitaire de Besancon
GlaxoSmithKline; French Society for Intensive Care; SmithKline Beecham

Completed

Early-onset Ventilator-associated Pneumonia in Adults: Comparison of 8 Versus 15 Days of Antibiotic Treatment

Pneumonia Ventilator Associated
UConn Health

Recruiting

Early Antibiotics After Aspiration in ICU Patients

Aspiration Pneumonia | Aspiration

United States
Azienda Sanitaria-Universitaria Integrata di Udine

Recruiting

Optimized Antibiotic Therapy in Patients With Subarachnoid Haemorrhage (ES) and Cerebral Haemorrhage (EC) (TANDEM)

Subarachnoid Hemorrhage | Therapeutic Drug Monitoring | Intracerebral Hemorrhage

Italy
Western Sydney Local Health District
Centre Of Research Excellence in Tuberculosis Control

Recruiting

The BLAST- 1 Trial - Cephalexin+Amoxicillin-clavulanate for Tuberculosis (BLAST)

Tuberculosis, Pulmonary

Australia
Children's Mercy Hospital Kansas City

Completed

Intravenous Versus Intravenous/Oral Antibiotics for Perforated Appendicitis

Perforated Appendicitis

United States
Xijing Hospital

Unknown

The Effect of Nebulization of Alkaline Solution on Treating XDRAB Pneumonia With C/S Plus Minocycline (NAEDRAP)

Pneumonia

China
Georgetown University
University of Maryland, Baltimore; National Center for Complementary and Integrative... and other collaborators

Completed

Mechanisms of Probiotics and Antibiotic-Associated Diarrhea (OURBIOTIC)

Antibiotic-associated Diarrhea

United States
Imperial College London
National Institute for Health Research, United Kingdom

Completed

Preschool Wheeze: Inflammation/Infection Guided Management (PrIGMa)

Asthma

United Kingdom
Cliniques universitaires Saint-Luc- Université...

Unknown

Prospective Randomized Study: Assessment of PRF Efficacy in Prevention of Jaw Osteonecrosis After Tooth Extraction (PRF)

Bisphosphonate-Associated Osteonecrosis of the Jaw

Belgium
Bayer

Completed

BAY12-8039, iv/Oral Pulmonary Abscess/Aspiration Pneumonia

Pneumonia, Aspiration | Lung Abscess

Germany
Eurofarma Laboratorios S.A.

Completed

A Non-inferiority, Multicenter and Randomized, Single-Dose Study About a Treatment to Hypolactasia (LAILAI) (EF099)

Hypolactasia

Brazil
Ottawa Heart Institute Research Corporation

Completed

Milrinone Versus Dobutamine in Critically Ill Patients

Acute Coronary Syndrome | Pulmonary Edema | Cardiogenic Shock | Low Cardiac Output Syndrome

Canada

Search clinical trials for: Beta-lactamase inhibitor

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