Search clinical trials for: Blood Coagulation Factor Inhibitors

Total 15282 results

Institute of Cancer Research, United Kingdom

Active, not recruiting

Stereotactic Body Radiotherapy for the Treatment of OPD (HALT)

NSCLC

United Kingdom, France, Switzerland, Italy, Spain
Northwestern University
National Cancer Institute (NCI)

Completed

Radiation Therapy and Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With High-Grade Lymphoma or Acute Lymphoblastic Leukemia

Lymphoma | Leukemia

United States
Washington University School of Medicine

Completed

CC-4047 (Pomalidomide) for Graft vs. Host Disease

Graft vs Host Disease

United States
Roswell Park Cancer Institute

Completed

KX2-391 in Treating Patients With Advanced Solid Tumors or Lymphoma That Did Not Respond to Treatment

Lymphoma | Small Intestine Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Lymphoproliferative Disorder

United States
Institut Paoli-Calmettes

Completed

Pilot Study Immunomonitoring Natural Killers Cells in Patients With Myeloid Malignancies Treated With Lenalidomide

Acute Myeloid Leukemia or Myelodysplasic Syndrome

France
Institut d'Investigació Biomèdica de Girona Dr....

Completed

Golimumab Effect in the Modulation of Gut Microbiota in Ulcerative Colitis (GOLI2015)

Ulcerative Colitis

Spain
Kliniken im Naturpark Altmuehltal

Unknown

Physiological Intermolecular Modification Spectroscopy (PIMS) in Ulcerative Colitis With Golimumab

Ulcerative Colitis

Germany
CytoSorbents Europe GmbH

Terminated

Ticagrelor Removal Study Using CytoSorb® 300 mL Device During CPB in Patients Undergoing Emergent Cardiothoracic Surgery (CyTation)

Acute Coronary Syndrome

Germany, Luxembourg
Hunan Cancer Hospital

Completed

Anti-PD-1 Antibody Plus Regorafenib in Refractory Microsatellite Stable Metastatic Colorectal Cancer

Metastatic Colorectal Adenocarcinoma

China
Seoul National University Hospital

Completed

Effects of Vildagliptine and Glimepiride on Glucose Variability

Diabetes Mellitus, Non-Insulin-Dependent

Korea, Republic of
Takeda

Completed

Efficacy Study of Pioglitazone and Glimepiride on the Rate of Progression of Atherosclerotic Disease. (CHICAGO)

Diabetes Mellitus

United States
UCB BIOSCIENCES, Inc.
PPD; Parexel

Completed

A Multicener, Postmarketing Study Evaluating the Transfer of Cimzia From the Mother to the Infant Via the Placenta (CRIB)

Rheumatoid Arthritis | Crohn's Disease | Psoriatic Arthritis | Ankylosing Spondylitis | Axial Spondyloarthritis (AxSpA) | Non-radiographic Evidence-AxSpA

Netherlands, Switzerland, United States, France
Baxalta now part of Shire

Terminated

Safety Study of Anti-Macrophage Migration Inhibitory Factor (Anti-MIF) Antibody in Lupus Nephritis

Systemic Lupus Erythematosus

Australia, United States, New Zealand, Mexico, Canada
Northwestern University
National Cancer Institute (NCI)

Completed

Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Patients With Hodgkin's Disease

Lymphoma

United States
Washington University School of Medicine
NeoImmune Tech

Withdrawn

Evaluating the Effect of NT-I7, a Long Acting Interleukin-7, to Increase Lymphocyte Counts and Enhance Immune Clearance of SARS-CoV-2 (COVID-19)

COVID-19 | SARS-CoV-2
Johns Hopkins University

Recruiting

Human Penile Allotransplantation

Wounds and Injuries | Amputation | Amputation, Traumatic | Urologic Surgical Procedures, Male | Amputation, Traumatic/Surgery | Penis/Transplantation | Penis/Surgery | Penis/Injuries

United States
Nanjing First Hospital, Nanjing Medical University

Recruiting

Improving Blood Lipid Management in Symptomatic Intracranial Atherosclerotic Stenosis on Clinical Outcome (sICASBLM)

Intracranial Artery Stenosis

China
Hoffmann-La Roche

Completed

A Comparative Study to Observe the Effect of Concomitant Use of Corticosteroid Treatment in Rheumatoid Arthritis (RA) Participants Who Are Treated With a Tumor Necrosis Factor (TNF) Inhibitor or Tocilizumab (TCZ) as Their Second Biological Treatment.

Rheumatoid Arthritis

Sweden
State University of New York at Buffalo
Genentech, Inc.

Active, not recruiting

Effect of Ocrelizumab on Cortical Lesion Accumulation in Patients With PPMS (ORATORIO-Cortical) (ORATORIO-Cort)

Primary Progressive Multiple Sclerosis

United States
State University of New York at Buffalo
Genentech, Inc.

Active, not recruiting

Effect of Ocrelizumab on Choroid Plexus Changes in Patients With PPMS (ORATORIO-CP)

Primary Progressive Multiple Sclerosis

United States
Pfizer

Not yet recruiting

A Study to Understand How Effective is Tofacitinib When Compared to Other Advanced Treatments in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis
Novartis Pharmaceuticals

Terminated

Comparison of Vildagliptin vs. Glimepiride on Glucose Variability in Metformin Uncontrolled Type 2 Diabetic Patients (VARIABLE)

Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC
Johnson & Johnson

Completed

Effect of Golimumab in Participants With Active Axial Spondyloarthritis (P07642, MK-8259-006) (GO-AHEAD)

Spondylitis, Ankylosing
Istituto Clinico Humanitas

Unknown

Golimumab in Steroid-dependent Ulcerative Colitis: Induction and Maintenance of Clinical and Endoscopic Remission (UC-GOL)

Colitis, Ulcerative

Italy
Donald B. Kohn, M.D.
California Institute for Regenerative Medicine (CIRM)

Active, not recruiting

Stem Cell Gene Therapy for Sickle Cell Disease

Sickle Cell Disease

United States
University of L'Aquila
TRIB s.r.l.

Completed

Treatment of Inherited Factor VII Deficiency (STER)

Factor VII Deficiency

Italy
University Ghent
Merck Sharp & Dohme LLC; the Flanders Institute for Biotechnology

Completed

Efficacy of Golimumab in Early Axial Spondyloarthritis in Relation to Gut Inflammation (GO-GUT)

Axial Spondyloarthritis

Belgium
Janssen Research & Development, LLC

No longer available

Pre-Approval Access to Golimumab Subcutaneous for the Treatment of Stage 3 Type-1 Diabetes Mellitus in Children and Young Adults

Diabetes Mellitus, Type 1

United States
Guy's and St Thomas' NHS Foundation Trust
Merck Sharp & Dohme LLC

Completed

Study of the Golimumab Exposure-Response Relationship Using Serum Trough Levels (GO-LEVEL)

Ulcerative Colitis

United Kingdom
Merck Sharp & Dohme LLC

Completed

Correlation of Soluble Suppression of Tumorigenicity 2 (ST2) With Golimumab (MK-8259) Response in Participants With Ulcerative Colitis (UC) (MK-8529-022). (EVOLUTION)

Colitis, Ulcerative
Janssen Pharmaceutical K.K.

Completed

A Safety and Effectiveness Study of Golimumab in Japanese Patients With Moderately to Severely Active Ulcerative Colitis.

Colitis, Ulcerative

Japan
Janssen-Cilag, S.A.

Terminated

Registry for Analysis of Compliance in Colombian Participants With Rheumatoid Arthritis Exposed to Golimumab (Go-Compl-Ar)

Rheumatoid Arthritis

Colombia
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Accuracy of a Subset of the Length-109 Probe Set Panel (a Genetic Test) in Predicting Response to Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis

Colitis, Ulcerative

France, Ukraine, United States, Poland, Bulgaria, Canada, Netherlands, Belgium, Russian Federation, Germany, Hungary, Czech Republic
House Research Institute
Janssen Services, LLC

Terminated

Intratympanic Injection for Autoimmune Inner Ear Disease (AIED)

Autoimmune Inner Ear Disease
Islamic Azad University, Najafabad Branch

Completed

Probiotics in the Treatment of Irritable Bowel Syndrome

Irritable Bowel Syndrome

Iran, Islamic Republic of
Pfizer

Terminated

Study Evaluating The Safety Of Xyntha In Usual Care Settings

Hemophilia A

United States, New Zealand
Zealand University Hospital

Completed

Non-responders to Antiplatelet Treatment in Acute Ischaemic Stroke) (NATIS)

Acute Ischemic Stroke

Denmark
Abbott Medical Devices

Terminated

Safety Study on Stopping Anticoagulation Medication in Patients With a History of Atrial Fibrillation (TACTIC AF)

Atrial Fibrillation

United States
Indiana University

Completed

Sinusoidal Obstruction Syndrome for Stem Cell Transplant Patients Biomarker Study (SOSBiomarker)

Sinusoidal Obstruction Syndrome

United States
Baylor College of Medicine

Completed

Protracted Etoposide During Induction Therapy for High Risk Neuroblastoma (PEPI)

Neuroblastoma

United States
Groupe d'Etude Therapeutique des Affections Inflammatoires...

Completed

Intensive Treatment to Reach the Target With Golimumab in ulcErative coliTis - In-TARGET (In-TARGET)

ULCERATIVE COLITIS

France, Belgium
Janssen Research & Development, LLC

Completed

A Study to Assess the Safety and Pharmacokinetics of Subcutaneously Administered Golimumab, a Human Anti-TNFα Antibody, in Pediatric Patients With Moderate to Severe Active Ulcerative Colitis

Colitis, Ulcerative

United States, France, Belgium, Israel, Canada, Netherlands, Austria, Poland, Denmark, Germany
Peking Union Medical College Hospital

Unknown

Effectiveness and Adherence of Golimumab in Rheumatoid Arthritis

Arthritis, Rheumatoid

China
Brigham and Women's Hospital
Johns Hopkins University; National Institute on Aging (NIA); Rutgers University

Completed

Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - TNFi vs Abatacept (DREAM)

Rheumatoid Arthritis

United States
Assistance Publique - Hôpitaux de Paris
Action Research Group; Bristol-Meyers Squibb & Pfizer

Completed

Anti-Thrombotic Strategy After Trans-Aortic Valve Implantation for Aortic Stenosis (ATLANTIS)

Symptomatic Aortic Stenosis | Eligible for Transcatheter Aortic Valve Replacement

France, Germany, Italy, Spain
Calico Life Sciences LLC
AbbVie

Recruiting

A Phase 1 Study With ABBV-CLS-484 in Subjects With Locally Advanced or Metastatic Tumors

Advanced Solid Tumor Cancer

United States, Korea, Republic of, Israel, Spain, Japan, France
Radboud University Medical Center

Completed

The Pharmacokinetics and Pharmacodynamics of Eculizumab in Patients With Paroxysmal Nocturnal Hemoglobinuria (PREPARE)

Paroxysmal Nocturnal Hemoglobinuria | Eculizumab | PK-PD

Netherlands
Johnson & Johnson Private Limited

Completed

A Study of Golimumab in the Treatment of Indian Participants With Active Spondyloarthropathy of Ankylosing Spondylitis or Psoriatic Arthritis

Arthritis, Psoriatic | Spondylitis, Ankylosing

India
Janssen Research & Development, LLC

Completed

A Study of SIMPONI® to Arrest Beta-cell Loss in Type 1 Diabetes (T1GER)

Diabetes Mellitus, Type 1

United States
Medical University of Graz

Completed

Golimumab in Juvenile Idiopathic Arthritis-associated Uveitis Failing Adalimumab

JIA Associated Uveitis

Search clinical trials for: Blood Coagulation Factor Inhibitors

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