Search clinical trials for: Blood Coagulation Factor Inhibitors

Total 15305 results

Janssen Research & Development, LLC

Completed

A Study of SIMPONI® to Arrest Beta-cell Loss in Type 1 Diabetes (T1GER)

Diabetes Mellitus, Type 1

United States
Medical University of Graz

Completed

Golimumab in Juvenile Idiopathic Arthritis-associated Uveitis Failing Adalimumab

JIA Associated Uveitis
National Institute of Diabetes and Digestive and...
University of South Florida

Withdrawn

Anti-TNFα to Delay or Prevent Progression to Stage 3 T1D

Diabetes Mellitus, Type 1
Janssen Research & Development, LLC

Completed

A Study to Evaluate SIMPONI (Golimumab) Therapy in Children, Adolescents and Young Adults With Pre-Symptomatic Type 1 Diabetes

Pre-Symptomatic Type 1 Diabetes

United States, Finland, Sweden
University Hospital, Ghent
Janssen Biologics B.V.

Completed

Exploration of TNF-alpha Blockade With Golimumab in the Induction of Clinical Remission in Patients With Early Peripheral Spondyloarthritis (SpA) According to ASAS-criteria (CRESPA)

Peripheral Spondylarthritis

Belgium
Centocor, Inc.

Completed

A Study of the Pharmacokinetics of Golimumab in Chinese Male Subjects

Healthy Adult Chinese Males

China
Radboud University Medical Center

Completed

The Pharmacokinetics and Pharmacodynamics of Eculizumab in Patients With Paroxysmal Nocturnal Hemoglobinuria (PREPARE)

Paroxysmal Nocturnal Hemoglobinuria | Eculizumab | PK-PD

Netherlands
Wenjie Zheng

Terminated

Golimumab for the Treatment of Refractory Behcet's Uveitis

Behcet Syndrome | Uveitis

China
Centocor, Inc.

Completed

A Pharmacokinetic (PK) and Pharmacodynamic (PD) Study of Golimumab in Patients With Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

United States
University of Malaya
University of Edinburgh

Withdrawn

Coronary Sinus Blood Sevoflurane and Desflurane Concentration and Lactate Changes in Patients Undergoing Heart Surgery (SEVO-DES)

Heart Diseases | Postoperative Complications | Myocardial Reperfusion Injury
Sun Yat-sen University

Recruiting

Whole-target Consolidation Therapy Under Systemic Therapy for Oligometastatic Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma

China
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

High-Dose Chemotherapy and Radiation Therapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Acute Leukemia in Remission

Leukemia | Bone Marrow Ablation

United States
Institute of Hematology & Blood Diseases Hospital

Recruiting

Anti-CD38 Antibody Treating APS With Thrombocytopenia

Thrombocytopenia | Antiphospholipid Syndrome

China
David Drobne

Unknown

Comparison of Two Different Golimumab Dosing Regimens for Ulcerative Colitis

Ulcerative Colitis

Slovenia
Janssen Inc.

Terminated

Observational Study of Golimumab Intravenous Infusion (GO-IV)

Rheumatoid Arthritis

Canada
Janssen Pharmaceutical K.K.
Mitsubishi Tanabe Pharma Corporation

Completed

A Safety and Efficacy Study of Golimumab (CNTO148) in Patients With Active Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

Japan
University of Zurich
Merck Sharp & Dohme LLC

Completed

Effectiveness of Golimumab in Patients With Ulcerative Colitis: Results of a Real-life Study in Switzerland

Ulcerative Colitis | Flare Up, Symptom

Switzerland
University of Zurich

Unknown

Real-world Data Regarding Treatment of Ulcerative Colitis Patients With Golimumab

Ulcerative Colitis | Flare Up, Symptom

Switzerland
Bio-Thera Solutions

Completed

Comparative Study of BAT2506 With Simponi® in Participants With Active Psoriatic Arthritis

Psoriatic Arthritis

China
Imperial College Healthcare NHS Trust
Merck Sharp & Dohme LLC; Imperial College London

Terminated

Thermography in Assessing Treatment Response to Golimumab in Psoriatic Arthritis (Go-Thermal)

Psoriatic Arthritis

United Kingdom
Merck Sharp & Dohme LLC

Completed

The Incidence of Extra-Articular Manifestations in Participants With Ankylosing Spondylitis Treated With Golimumab (MK-8259-012) (GO-EASY)

Ankylosing Spondylitis
Centocor, Inc.
Centocor BV

Completed

A Study of Safety and Efficacy of CNTO 148 in Patients With Severe Persistent Asthma

Asthma

United Kingdom, United States, Germany, France, Poland, Bulgaria, Belgium, Czech Republic, Hungary, Netherlands, Sweden
H. Lee Moffitt Cancer Center and Research Institute
Bristol-Myers Squibb; Boehringer Ingelheim

Completed

Phase I Trial of Afatinib (BIBW 2992) and Dasatinib in Non-small Cell Lung Cancer (NSCLC)

Lung Cancer | Non-small Cell Lung Cancer (NSCLC)

United States
Seoul National University Hospital

Unknown

Clinical Study of Anti-tumor Necrosis Factor Therapy in Patients With Takayasu Arteritis

Takayasu's Arteritis

Korea, Republic of
Daiichi Sankyo, Inc.

Completed

A Study of DU-176b in Preventing Blood Clots After Hip Replacement Surgery

Thrombosis | Hip Replacement

Ukraine, United States, Canada, Russian Federation, Hungary, Latvia, Denmark
Centre Oscar Lambret

Completed

Imatinib Mesylate And Cyclophosphamide In Metronomic Administration: Dose Escalation Study Of Imatinib Mesylate (PALANGI3)

Cancer

France
Boehringer Ingelheim

Completed

Afatinib as Second-line Therapy for Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Mutation

Carcinoma, Non-Small-Cell Lung

Serbia, Thailand, Poland, Romania, Egypt, Philippines, Malaysia
Asan Medical Center
Hanyang University; Kangbuk Samsung Hospital; Eulji University Hospital

Unknown

Reversible Cerebral Vasoconstriction Syndrome and Varicella Zoster Virus (RCVS&VZV)

Reversible Cerebral Vasoconstriction Syndrome | Varicella-zoster Virus Infection

Korea, Republic of
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Withdrawn

BAY 56-3722 in Treating Patients With Recurrent, Unresectable, or Metastatic Kidney Cancer

Stage IV Renal Cell Cancer | Recurrent Renal Cell Cancer

United States
University Hospital, Montpellier

Recruiting

Efficacy of a Sequential Treatment Strategy in Rheumatoid Arthritis (SEQUENS-RA)

Rheumatoid Arthritis

France, Monaco
Centre Hospitalier Universitaire Dijon

Recruiting

Development of a Device for Evaluating Primary Hemostasis Under Whole Blood Flow Conditions (INDONESIA)

Von Willebrand Diseases | Major Constitutional Thrombopathy | Patient on Antiplatelet Drugs

France
National Cancer Institute (NCI)

Completed

Interleukin-12 in Treating Patients With Ovarian Epithelial Cancer or Primary Peritoneal Cancer

Primary Peritoneal Cavity Cancer | Recurrent Ovarian Epithelial Cancer

United States
GlaxoSmithKline

Completed

A Follow-up Extension Study to Evaluate the Persistence of Immune Response to GSK Biologicals' HPV Vaccine in Healthy Chinese Female Subjects Who Received Three Doses of the Vaccine in the HPV-058 Study

Cervical Intraepithelial Neoplasia

China
Chinese University of Hong Kong

Completed

Effect of Anti-TNF (Alpha) Treatment on Vascular Stiffness in Ankylosing Spondylitis (AS) (AS)

Ankylosing Spondylitis(AS)

China
Merck Sharp & Dohme LLC

Completed

Golimumab Utilization and Impact on Ulcerative Colitis (MK-8259-032) (GO-COLITIS)

Ulcerative Colitis

United Kingdom
University of Pennsylvania
Janssen Scientific Affairs, LLC

Recruiting

Guselkumab vs Golimumab in PsA TNF Inadequate Responder Patients (EVOLUTION)

Psoriatic Arthritis

United States
Janssen Research & Development, LLC

Recruiting

A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Crohn's Disease (DUET-CD)

Crohn's Disease

United States, Denmark, Belgium, Taiwan, Italy, Korea, Republic of, Germany, United Kingdom, Israel, Malaysia, Poland, Japan, New Zealand, Netherlands, China, Canada, France, Spain, Norway, Singapore, Croatia, Brazil, Switzerland, Aus... and more
Janssen Inc.

Completed

Golimumab for Adherence in Rheumatoid Arthritis (GO FAR)

Arthritis, Rheumatoid

Canada
UCB Biopharma SRL

Available

CUP Certolizumab Pegol (CDP-870) in Adults Suffering From Crohn's Disease (CD)

Crohn's Disease
UCB Biopharma SRL

Available

Named Patient Program With Certolizumab Pegol in Adults Suffering From Rheumatoid Aarthritis (RA)

Rheumatoid Arthritis
Janssen Pharmaceutica

Withdrawn

A Study to Assess the Safety and Effectiveness of Golimumab in Filipino Patients With Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

Rheumatoid Arthritis | Psoriatic Arthritis | Ankylosing Spondylitis
Beth Israel Deaconess Medical Center
National Cancer Institute (NCI); Massachusetts General Hospital; Dana-Farber... and other collaborators

Active, not recruiting

Vaccination of Patients With Ovarian Cancer With Dendritic Cell/Tumor Fusions With Granulocyte Macrophage Colony-stimulating Factor (GM-CSF) and Imiquimod

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cancer

United States
Weill Medical College of Cornell University
Celgene

Completed

Study of Decadron, Biaxin, and Pomalidomide in Relapsed/Refractory Myeloma

Multiple Myeloma

United States
National Institute of Diabetes and Digestive and...
Washington University School of Medicine; Merck Sharp & Dohme LLC; University... and other collaborators

Completed

HALT Progression of Polycystic Kidney Disease Study A (HALT PKD A)

Kidney, Polycystic

United States
Sohag University

Not yet recruiting

Evaluation of Risk Factors and Outcome of Thrombosis in Children

Thrombosis in Children

Egypt
Baxalta now part of Shire

Completed

Phase 1 Study of Anti-Macrophage Migration Inhibitory Factor (Anti-MIF) Antibody in Solid Tumors

Malignant Solid Tumors | Metastatic Adenocarcinoma of the Colon or Rectum

Germany, United States
Stanford University
National Institutes of Health (NIH)

Active, not recruiting

Serial Ultrasound in Metastatic Renal Cell Carcinoma (mRCC)

Kidney Cancer | Renal Cell Carcinoma | Metastatic Renal Cell Carcinoma

United States
Ottawa Regional Cancer Centre

Unknown

Combination Chemotherapy in Treating Patients With Intermediate-Grade or High-Grade Non-Hodgkin's Lymphoma Who Have Not Responded to Anthracycline-Containing Combination Chemotherapy

Lymphoma

Canada
NCIC Clinical Trials Group
Merck Frosst Canada Ltd.

Completed

MK-0646, Etoposide, and Cisplatin in Treating Patients With Extensive-Stage Small Cell Lung Cancer

Lung Cancer

Canada
Peking Union Medical College Hospital
Xuanwu Hospital, Beijing; Beijing Tongren Hospital

Unknown

Comparison of Stent and Prothesis Bypass in Superficial Femoral Artery (SPACIAL)

Vascular Diseases | Arterial Occlusive Diseases

China

Search clinical trials for: Blood Coagulation Factor Inhibitors

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