Search clinical trials for: Brolucizumab ophthalmic solution

Total 19485 results

Santen Inc.

Completed

DE-117 Spectrum 5 Study

Primary Open-angle Glaucoma and Ocular Hypertension

United States
Trefoil Therapeutics, Inc.

Completed

Dose Escalation TTHX1114 Ophthalmic Solution (EPI)

Corneal Epithelial Degeneration

United States
Mimetogen Pharmaceuticals USA, Inc.

Completed

Tavilermide Ophthalmic Solution for the Treatment of Dry Eye

Dry Eye | Keratoconjunctivitis Sicca

United States
Allysta Pharmaceutical

Completed

ALY688 Ophthalmic Solution in Subjects With Dry Eye Disease (OASIS-1)

Dry Eye

United States
Chakshu Research, Inc.

Completed

An Open-Label Study of an Ophthalmic Solution to Reduce Intraocular Pressure in Patients With Ocular Hypertension

Ocular Hypertension

United States
Chakshu Research, Inc.

Unknown

An Open-Label Study of the Effect of an Ophthalmic Solution on Asteroid Hyalosis

Asteroid Hyalosis

United States
Othera Pharmaceuticals

Terminated

Study of OT-551 Eye Drops to Prevent or Delay Progression of Nuclear Cataracts Following Vitreous Removal

Epiretinal Membrane | Macular Hole

United States
State University of New York College of Optometry
Novartis Pharmaceuticals

Completed

Lifitegrast 5% for the Treatment of Dry Eye In Habitual Soft Contact Lens Wearers

Dry Eye

United States
Santen Pharmaceutical Co., Ltd.

Completed

Safety and Efficacy Study of DE-104 Ophthalmic Solution to Treat Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

Japan
BRIM Biotechnology Inc.

Recruiting

Assessment of the Safety and Efficacy of BRM421 Ophthalmic Solutions in Dry Eye Subjects.

Dry Eye Disease

United States
University of California, Los Angeles

Recruiting

Corneal Nerves After Treatment With Cenegermin

Neurotrophic Keratitis

United States
Santen Pharmaceutical Co., Ltd.

Completed

Pharmacokinetic Study of STN1012600 Ophthalmic Solution in Healthy Adult Males Volunteers

Healthy Adult Males Volunteers

Japan
Massachusetts Eye and Ear Infirmary

Completed

Netarsudil Use After Descemetorhexis Without Endothelial Keratoplasty

Cataract | Fuchs' Endothelial Dystrophy

United States
Kissei Pharmaceutical Co., Ltd.

Completed

A Long-term Study of KCT-0809 in Dry Eye Patients With Sjögren's Syndrome

Dry Eye With Sjögren's Syndrome

Japan
Santen Pharmaceutical Co., Ltd.

Completed

DE-111 Ophthalmic Solution in Patients With Open Angle Glaucoma or Ocular Hypertension

Open Angle Glaucoma or Ocular Hypertension

Japan
Santen Pharmaceutical Co., Ltd.

Completed

A Long-term Study of DE-114 Ophthalmic Solution in Patients With Allergic Conjunctivitis

Allergic Conjunctivitis

Japan
Allergan

Completed

Safety and Efficacy of Relestat Ophthalmic Solution 0.05% for Allergic Conjunctivitis in Korea

Conjunctivitis, Allergic

Korea, Republic of
Alcon Research

Completed

A Study of AL-38583 Ophthalmic Solution 0.05%, 0.010% Versus AL-38583 Vehicle for Dry Eye

Dry Eye
Aerie Pharmaceuticals

Completed

A Long-Term Safety Study Evaluating the Safety and Systemic Exposure of AR-15512 (COMET-4)

Dry Eye Disease

United States
ONL Therapeutics

Completed

A Phase 2 Study to Assess the Safety and Efficacy of Intravitreal ONL1204 Ophthalmic Solution in Subjects With Mac-off Retinal Detachment

Rhegmatogenous Retinal Detachment - Macula Off

United States
Aerie Pharmaceuticals

Completed

Study Assessing Ocular and Systemic Safety of AR-13324 in Healthy Volunteers

Healthy

United States
HanAll BioPharma Co., Ltd.
Daewoong Pharmaceutical Co. LTD.

Completed

A Study to Assess Efficacy and Safety of HL036 in Subjects With Dry Eyes (VELOS-2)

Dry Eye

United States
Harbour BioMed (Guangzhou) Co. Ltd.

Completed

A Study Evaluating the Efficacy and Safety on Moderate to Severe Dry Eye

Dry Eye

China
Merck Sharp & Dohme LLC

Completed

A Study to Determine the Safety and Tolerability of Escalating Doses of INS365 Ophthalmic Solution

Dry Eye Disease
Merck Sharp & Dohme LLC

Completed

Study of INS115644 Ophthalmic Solution in Subjects With Ocular Hypertension or Glaucoma

Ocular Hypertension | Open Angle Glaucoma
ONL Therapeutics

Completed

ONL1204 Ophthalmic Solution in Patients With Geographic Atrophy Associated With Age-related Macular Degeneration

Geographic Atrophy

New Zealand, Australia
Aerie Pharmaceuticals

Completed

Study Evaluating the Safety and Efficacy of AR-15512 (COMET-3)

Dry Eye Disease

United States
Aerie Pharmaceuticals

Completed

Study Evaluating the Safety and Efficacy of AR-15512 (COMET-2)

Dry Eye Disease

United States
Kissei Pharmaceutical Co., Ltd.

Completed

A Phase III Study of KCT-0809 in Dry Eye Patients With Sjögren's Syndrome

Dry Eye With Sjögren's Syndrome

Japan
Merck Sharp & Dohme LLC

Completed

Study of INS365 Ophthalmic Solution in Subjects With Dry Eye Disease

Dry Eye Disease
Kissei Pharmaceutical Co., Ltd.

Completed

A Late Phase II Study of KCT-0809 in Patients With Dry Eye Syndromes

Dry Eye Syndromes

Japan
Allergan

Completed

A Safety, Efficacy and Pharmacokinetic Study of AGN-199201 and AGN-190584 in Patients With Presbyopia

Presbyopia

United States
Topivert Pharma Ltd

Completed

Study of TOP1630 for Dry Eye Syndrome (THEIA-1)

Dry Eye Syndrome

United States
Parion Sciences

Terminated

Study of the Pharmacodynamic Activity of P-321 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye Disease

Dry Eye Disease

United States
Amneal Pharmaceuticals, LLC
CBCC Global Inc.; Amneal EU, Limited

Not yet recruiting

A Randomized, Double-blind, Parallel-group, Two-arm, Multiple Dose, Multicenter, Bioequivalence Study With Clinical Endpoint in the Treatment of Subjects With Chronic Open-angle Glaucoma or Ocular Hypertension in Both Eyes

Ocular Hypertension | Open-angle Glaucoma

United States
Santen Inc.

Completed

Safety and Efficacy Study of DE-104 Ophthalmic Solution to Treat Open-angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

United States
Stealth BioTherapeutics Inc.

Completed

A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide Topical Ophthalmic Solution for Treatment of Leber's Hereditary Optic Neuropathy

Leber's Hereditary Optic Neuropathy

United States
Harbour BioMed (Guangzhou) Co. Ltd.

Recruiting

A Study Evaluating HBM9036 Efficacy and Safety on Moderate to Severe Dry Eye

Dry Eye

China
OcuTerra Therapeutics, Inc.

Completed

Safety and Exploratory Efficacy Study of SF0166 in the Treatment of Neovascular Age-Related Macular Degeneration (AMD)

Age-Related Macular Degeneration

United States
Aerie Pharmaceuticals

Completed

Study of Rhopressa® for the Reduction of Elevated Intraocular Pressure in Patients With Glaucoma or Ocular Hypertension in a Real-world Setting

Ocular Hypertension | Glaucoma, Open-Angle

United States
Alcon, a Novartis Company
Novartis Institutes for BioMedical Research

Completed

LME636 in the Relief of Persistent Ocular Discomfort in Subjects With Severe Dry Eye Disease

Dry Eye
Merck Sharp & Dohme LLC

Completed

Study of INS365 Ophthalmic Solution in Subjects With Dry Eye Disease

Dry Eye Disease
Merck Sharp & Dohme LLC

Completed

Study of Diquafosol Tetrasodium Ophthalmic Solution in Subjects With Dry Eye Disease

Dry Eye Disease
Merck Sharp & Dohme LLC

Completed

A Study of INS365 Ophthalmic Solution in Patients With Moderate to Severe Dry Eye Disease

Dry Eye Disease
Alcon Research

Completed

ESBA105 in Patients With Severe Dry Eye

Eyes Dry Chronic

United States
Chakshu Research, Inc.

Unknown

Safety and Efficacy Study of an Ophthalmic Solution in Patients With Age-Related Cataract

Cataract

United States
Vista Klinik
Novartis

Terminated

Intravitreal Brolucizumab in Neovascular Age-related Macular Degeneration With Limited Response to Aflibercept (ROBIN)

Neovascular Age-related Macular Degeneration

Switzerland
Aldeyra Therapeutics, Inc.

Completed

An Exploratory Clinical Trial to Assess Safety and Tolerability in Subjects With Dry Eye Disease

Dry Eye

Canada
Alcon Research

Completed

Travoprost 3-Month Safety and Efficacy Study

Ocular Hypertension | Open-Angle Glaucoma
Aldeyra Therapeutics, Inc.

Completed

SOLACE Trial - A Phase 3 Trial in Subjects With Non-infectious Anterior-uveitis.

Non-infectious Anterior Uveitis

United States

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