Search clinical trials for: Buprenorphine Naloxone

Total 700 results

MetroHealth Medical Center
National Institute on Drug Abuse (NIDA)

Completed

Effect of Heroin Use on Immune Activation and Cardiovascular Risk in HIV

Cardiovascular Diseases | HIV Infection | Opioid-use Disorder

United States
Teva Pharmaceuticals USA

Withdrawn

An Open-Label, Single-Center Study to Evaluate the Exposure-Response Relationship Between the Plasma Drug Concentrations and the Change From Baseline in QTc at Steady State Following Once-daily Administration of CASSIPA® in Opioid Dependent Subjects.

Evaluation of QTc Interval
Indivior Inc.

Completed

Multiple Dose Study of Blockade of Opioid Effects by Injections of Buprenorphine in Participants With Opioid Disorder

Opioid Use Disorder

United States
Virginia Commonwealth University
National Institute on Drug Abuse (NIDA)

Completed

Drug-drug Interaction Study of Lemborexant as an Adjunctive Treatment for Buprenorphine/Naloxone for Opioid Use Disorder

Opioid Use Disorder | Drug Interaction | Analgesics

United States
Friends Research Institute, Inc.
National Institute on Drug Abuse (NIDA)

Completed

Buprenorphine for Prisoners

Heroin Addiction

United States
Janssen-Cilag A.G., Switzerland

Completed

Comparison of Two Dosage Strengths of Transdermal Fentanyl Versus Transdermal Buprenorphine and Placebo in Acute Pain Models in Healthy Volunteers.

Pain
Indivior Inc.

Completed

Safety and Tolerability Study of Depot Buprenorphine in Treatment Seeking Subjects With Opioid Use Disorder

Opioid Use Disorder | Opioid-related Disorders

United States
Indivior Inc.

Completed

Single Ascending Dose Study of RBP-6000 (SAD)

Opioid Use Disorder

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Medications Development for Drug Abuse Disorders

Opioid Dependence | Opioid Related Disorders | Opioid Addiction

United States
Butler Hospital

Completed

Neuroimaging Predictors of Relapse During Treatment for Opiate Dependence

Opioid Addiction

United States
NYU Langone Health
NYC Health + Hospitals

Completed

XRB vs. SLB in Jail and at Re-entry: Pilot, Proof of Concept

Opioid Dependence

United States
New York State Psychiatric Institute
Schering-Plough

Completed

Abuse Liability of Suboxone Versus Subutex

Opioid-related Disorders

United States
Duke University
National Institute of Allergy and Infectious Diseases (NIAID); Center for AIDS...

Completed

Providing PrEP, Hepatitis C Treatment, and MOUD Through Telemedicine at Greensboro SSP (PARTNERUP)

Hepatitis C | Hiv | Opioid Use Disorder | Opioid Use | Risk Reduction

United States
Indivior Inc.

Completed

Treatment Seeking Participants With Opioid Use Disorders Assessing Tolerability of Depot Injections of Buprenorphine

Opioid Dependence | Opioid Related Disorders

United States
Yale University
National Institute on Drug Abuse (NIDA); University of Malaya

Active, not recruiting

Addiction, HIV and Tuberculosis in Malaysian Criminal Justice Settings (HARAPAN II)

Hepatitis | HIV/AIDS | Tuberculosis | Addiction | Opioid Dependence

Malaysia
University of Wisconsin, Madison
University of Wisconsin, Milwaukee

Completed

Treatment for Opioid Dependent Offenders

Opioid Dependence

United States
AstraZeneca
Parexel

Recruiting

Drug-Drug Interaction and Safety of AZD4041 Study (Part 1) and Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of AZD4041 Study in Opioid Use Disorder (Part 2).

Opioid Use Disorder

United States
The University of Texas Health Science Center,...

Recruiting

Young Houston Emergency Opioid Engagement System (YHEROES)

Substance Use Disorders | Opioid Dependence | Opioid Use | Opioid-use Disorder | Opioid Overdose

United States
Viramal Limited

Completed

Study to Determine Intraperitoneal,Tissue, Serum Concentrations of VML-0501 Following Five Days of Daily Vaginal Single Dose of VML-0501 (100 mg Danazol), in Comparison to Oral Danazol Capsules Daily 600 mg), in Women With Signs and Symptoms of Endometriosis Undergoing Laparoscopy

Endometriosis

Italy
IVI Madrid

Completed

Effects of Telomerase Reactivation With Danazol in Ovarian Function.

Ovarian Reserve

Spain
Samjin Pharmaceutical Co., Ltd.

Completed

A Phase 4 Clinical Study to Investigate the Efficacy and Safety of Naloxone HCI IV in Patients With Stroke

Stroke, Acute

Korea, Republic of
Laura Fanucchi
National Institute on Drug Abuse (NIDA)

Recruiting

Integrated Outpatient Treatment of Opioid Use Disorder and Severe Injection Related Infections (BOPAT)

Drug Use | Opioid-use Disorder

United States
Merck Sharp & Dohme LLC

Completed

A Randomized Acceptability and Safety Study of Suboxone Induction in Heroin Users (P05042)(COMPLETED)

Opiate Dependence | Substance Dependence | Drug Dependence
Virginia Polytechnic Institute and State University

Completed

Efficacy of Computer Delivered Community Reinforcement Approach (CRA) (Bup II) (CAT)

Opiate Addiction

United States
Korean Society of Hematology

Not yet recruiting

A Study of Treatment-free Remission in Chronic Phase Chronic Myeloid Leukemia (AsterA)

Chronic Myeloid Leukemia, Chronic Phase
Judith Feinberg

Unknown

Nasal Naloxone for Narcotic Overdose

Drug Overdose

United States
Yale University
United States Department of Defense

Completed

Buprenorphine Treatment for Opioid Dependence

Opioid Dependence

United States
mads u werner
University of Kentucky

Completed

Effect of High-dose Target-controlled Naloxone Infusion on Pain and Hyperalgesia During a Burn Injury (TCI-NX-BI)

Healthy Subjects

Denmark
S.L.A. Pharma AG

Completed

Naloxone SR Capsules in Patients With Opioid Induced Constipation

Chronic Pain | Opioid Induced Constipation

Germany, United Kingdom
mads u werner
University of Kentucky

Completed

Effect of High-dose Naloxone Following Third Molar Extraction (TME)

Pain, Acute | Healthy Subjects | Hyperalgesia | Sensitization, Central | Inflammations, Endodontic

Denmark
Gauda, Estelle B., M.D.
Johns Hopkins University; Johns Hopkins All Children's Hospital

Unknown

Sublingual Buprenorphine Treatment for Neonatal Abstinence Syndrome - Pilot Study

Withdrawal | Drug; Withdrawal Symptoms, Neonatal | Fetus and Newborn Affected by Other Maternal Medication

United States
Pocket Naloxone Corp

Completed

Pharmacokinetic Evaluation of a New Naloxone Nasal Swab, Naloxone Nasal Spray, and Intramuscular Naloxone Injection in Healthy Volunteers

Opioid Overdose

Canada
Indivior Inc.

Completed

Single Dose Pharmacokinetics of Suboxone Study in Hepatic Impaired Subjects

Hepatic Impairment | Hepatic Failure | Chronic Hepatitis C Infection With Hepatic Coma

United States
Norwegian University of Science and Technology
St. Olavs Hospital; Smerud Medical Research International AS; A/S Den norske...

Completed

Bioavailability of Nasal Naloxone and Injected Naloxone Compared (OPI-15-002)

Drug Overdose

Norway
INSYS Therapeutics Inc

Completed

A Study to Compare Bioavailability of Naloxone Nasal Spray, Naloxone Hydrochloride (HCl) Intravenous (IV) and Intramuscular Injection (IM) in Healthy Volunteers

Healthy Volunteer

United States
University of California, Los Angeles

Completed

Optimizing Outcomes Using Suboxone for Opiate Dependence (OpBup)

Opioid Dependency

United States
Duke University

Completed

Providing Suboxone and PrEP Using Telemedicine

Hiv | Opioid Use | Opioid-use Disorder | Risk Reduction

United States
INSYS Therapeutics Inc

Completed

A Study to Compare Bioavailability of Naloxone Nasal Spray and Naloxone Hydrochloride (HCl) Intramuscular Injection (IM) in Healthy Volunteers

Healthy Volunteer

United States
Norwegian University of Science and Technology
St. Olavs Hospital

Completed

Pharmacokinetics and Pharmacodynamics of a New Formulation of Nasal Naloxone for Prehospital Use (OPI-14-001)

Drug Overdose

Norway
Leiden University Medical Center
U.S. Food and Drug Administration (FDA)

Recruiting

Reversal of Opioid-induced Respiratory Depression With Opioid Antagonists (ROAR)

Chronic Opioid Use | Opioid Induced Respiratory Depression

Netherlands
University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Completed

Remote Observed Dosing of Suboxone to Improve Clinical Practice

Opioid Dependence | Opioid-use Disorder | Opiate Dependence

United States
Norwegian University of Science and Technology
St. Olavs Hospital; University of Iceland

Completed

A Pilot Study of the Bioavailability of Nasal Naloxone

Drug Overdose

Norway
University of Washington

Unknown

Subjective Analgesic Effects of Naloxone and Virtual Reality (Narcan)

Pain

United States
Parc de Salut Mar
Food and Drug Administration (FDA)

Recruiting

Pharmacokinetics of Intravenous and Intranasal Formulations of Naloxone in Healthy Volunteers.

Healthy

Spain
University of Minnesota

Completed

Naloxone, Hypoglycemia and Exercise

Diabetes Mellitus, Type 1

United States
Finnish Institute for Health and Welfare

Completed

Treatment of Gambling Disorder With Fast Acting Opiate Antagonist, Naloxone Nasal Spray (NALPILO)

Naloxone | Gambling | Spray | Opioid

Finland
Steve N. Caritis, MD
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Terminated

Pharmacologically-based Strategies for Opioid Substitution Therapy During Pregnancy

Pregnancy | Opiate Addiction

United States
University of New Mexico

Not yet recruiting

Nalmefene vs Naloxone for the Treatment of Recurrent Respiratory Depression After Opioid Overdose

Opioid Overdose | Opiate Overdose

United States
Emergent BioSolutions

Completed

Pharmacokinetics (PK) and Safety of Multiple Doses of Intranasal Naloxone in Healthy Adults

Opioid Overdose

United States
Kaiser Permanente
National Institute on Drug Abuse (NIDA); Denver Health and Hospital Authority

Completed

Impact of Direct Outreach to Expand Access to Naloxone in the Context of Standing Orders

Risk Behavior | Opioid Abuse | Overdose

United States

Search clinical trials for: Buprenorphine Naloxone

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