Search clinical trials for: CP-690,550

Total 745 results

University Health Network, Toronto

Terminated

Safety Study of Radiation and CP-675,206 Infusion for Breast Cancer Patients

Metastatic Breast Cancer

Canada
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Durvalumab and Tremelimumab in Treating Chemotherapy Naive Patients With Metastatic Castration-Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Prostate Adenocarcinoma | Stage IV Prostate Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Bone | Stage IVA Prostate Cancer AJCC v8 | Stage IVB Prostate Cancer AJCC v8

United States
VA Office of Research and Development
VA Maryland Health Care System

Recruiting

Assessment and Treatment for Chronic Pain in Veterans With Serious Mental Illness (CPSMI)

Psychotic Disorders | Schizophrenia | Chronic Pain | Bipolar Disorder | Affective Disorders, Psychotic

United States
VA Office of Research and Development

Completed

Mindful Action for Pain (MAP)

Chronic Pain

United States
Regen Lab SA

Unknown

Comparative Evaluation of A-CP HA Kit, Hyaluronic Acid and Placebo for the Treatment of Knee Osteoarthritis

Knee Osteoarthritis

United States
Arog Pharmaceuticals, Inc.

Completed

Study of Crenolanib in Recurrent/Refractory Glioblastoma With PDGFRA Gene Amplification

Recurrent/Refractory Glioblastoma

United States
Mary Feng, MD
AstraZeneca

Recruiting

Hypofractionated Radiotherapy Followed by Durvalumab With or Without Tremelimumab for Liver Cancer After Progression on PD-1 Inhibition

Advanced Hepatocellular Carcinoma | Stage III Hepatocellular Carcinoma AJCC v8 | Stage IIIA Hepatocellular Carcinoma AJCC v8 | Stage IV Hepatocellular Carcinoma AJCC v8 | Stage IVA Hepatocellular Carcinoma AJCC v8 | Stage IVB Hepatocellular Carcinoma AJCC v8 | Stage IIIB Hepatocellular Carcinoma...

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Durvalumab, Tremelimumab, and Selumetinib in Treating Participants With Recurrent or Stage IV Non-small Cell Lung Cancer

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Recurrent Lung Non-Small Cell Carcinoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Tremelimumab and Durvalumab in Treating Patients With Colorectal Cancer With Liver Metastases That Can Be Removed by Surgery

Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Metastatic Carcinoma in the Liver | Resectable Mass

United States
F. Stephen Hodi, MD
MedImmune LLC

Completed

Phase I Clinical Trial of Tremelimumab Plus MEDI3617 in Patients With Unresectable Stage III or Stage IV Melanoma

Metastatic Melanoma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Durvalumab and Tremelimumab in Treating Patients With Microsatellite Stable Metastatic Colorectal Cancer to the Liver

MLH1 Gene Mutation | Stage IV Colorectal Cancer | Stage IVA Colorectal Cancer | Stage IVB Colorectal Cancer | Metastatic Carcinoma in the Liver | MSH6 Gene Mutation | PMS2 Gene Mutation

United States
Medical University of Graz

Not yet recruiting

Impact of Hepatitis B Immunoglobulins in Patients With Chronic Hepatitis B on Hepatocellular Carcinoma - a Proof of Concept Study (HBIG)

Hepatocellular Carcinoma | HBV
Milton S. Hershey Medical Center
University of Kentucky; Hospice Foundation of America

Recruiting

Project Talk Trial: Engaging Underserved Communities in End-of-life Conversations

Communication | Terminal Illness | Chronic Illness | Advance Care Planning | Advance Directives

United States
Biotest

Active, not recruiting

Prevention of Maternal-fetal Cytomegalovirus Transmission After Primary Maternal Infection, GW ≤ 14 (PreCyssion) (PreCyssion)

Congenital Cytomegalovirus Infection

Germany
University of Wisconsin, Madison
Pfizer

Withdrawn

Study of CP-675,206 in Bacillus Calmette-Guerin (BCG)-Resistant Bladder Cancer

Bladder Cancer
AstraZeneca

Completed

A Rollover Study for Patients Who Received Tremelimumab in Other Protocols, to Allow the Patients Access to Tremelimumab Until This Agent Becomes Commercially Available or Development is Discontinued.

Melanoma | Neoplasms | Renal Cell Carcinoma | Prostatic Neoplasms | Colorectal Neoplasms | Patients Who Have/Have Had Melanoma and Other Tumors

United States, United Kingdom
Grupo Espanol de Tumores Neuroendocrinos

Completed

Durvalumab (MEDI4736) Plus Tremelimumab for Advanced Neuroendocrine Neoplasms of Gastroenteropancreatic or Lung Origin (DUNE)

Neuroendocrine Tumors | Neuroendocrine Neoplasm of Lung

Spain
China Medical University Hospital

Completed

The Effect of Probiotics on Type 1 Diabetes Mellitus in Children

Type 1 Diabetes Mellitus

Taiwan
Arog Pharmaceuticals, Inc.

Completed

Study of Crenolanib for the Treatment of Patients With Advanced GIST With the D842-related Mutations and Deletions in the PDGFRA Gene

D842-related Mutant GIST

United States
National Cancer Institute (NCI)

Active, not recruiting

Erlotinib Hydrochloride in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Completely Removed by Surgery (An ALCHEMIST Treatment Trial)

Lung Non-Squamous Non-Small Cell Carcinoma | Stage IB Lung Non-Small Cell Carcinoma AJCC v7 | Stage II Lung Non-Small Cell Cancer AJCC v7 | Stage IIA Lung Non-Small Cell Carcinoma AJCC v7 | Stage IIB Lung Non-Small Cell Carcinoma AJCC v7 | Stage IIIA Lung Non-Small Cell Cancer AJCC v7

United States, Puerto Rico
Arog Pharmaceuticals, Inc.

Withdrawn

A Phase 2 Study in Patients With Advanced Non-Small Cell Lung Cancer Using New Agents With and Without Docetaxel.

Carcinoma, Non-Small-Cell Lung
Charles University, Czech Republic

Recruiting

Hippotherapy in Children With Spinal Muscular Atrophy (HIPOSMA)

Spinal Muscular Atrophy

Czechia
Pfizer

Completed

Study To Examine Effect Of CP-866,087 On Consumption And Craving Of Alcohol In Alcohol Dependent Subjects.

Alcoholism

United States
AstraZeneca

Completed

Study of Ticilimumab in Patients With Metastatic Colorectal Cancer Whose Disease Had Progressed After Treatment

Colorectal Neoplasms

United States, Canada
Shandong University
The Affiliated Hospital of Qingdao University; Taian City Central Hospital; Weifang... and other collaborators

Completed

The Study About the Selection of Time for Retreatment of Helicobacter Pylori After Eradication Failure

Helicobacter Pylori Infection

China
Roswell Park Cancer Institute
AstraZeneca

Active, not recruiting

Olaparib, Durvalumab, and Tremelimumab in Treating Patients With Recurrent or Refractory Ovarian, Fallopian Tube or Primary Peritoneal Cancer With BRCA1 or BRCA2 Mutation

BRCA1 Gene Mutation | BRCA2 Gene Mutation | Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Ovarian Serous Adenocarcinoma

United States
Dana-Farber Cancer Institute
AstraZeneca

Suspended

A Phase 2 Study of Durvalumab in Combination With Tremelimumab in Malignant Pleural Mesothelioma

Mesothelioma

United States
Northwestern University
National Cancer Institute (NCI); AstraZeneca; MedImmune LLC

Completed

Tremelimumab and Durvalumab in Combination or Alone in Treating Patients With Recurrent Malignant Glioma

Malignant Glioma | Recurrent Glioblastoma

United States
GERCOR - Multidisciplinary Oncology Cooperative...
AstraZeneca

Active, not recruiting

Durvalumab + Tremelimumab ± Paclitaxel in Advanced BTC After Platinum Chemotherapy. (IMMUNO-BIL)

Advanced Biliary Tract Carcinoma

France
Columbia University

Withdrawn

Durvalumab and Tremelimumab for Adjuvant Therapy of Resected NSCLC

Non-small Cell Lung Cancer
Pfizer

Terminated

Long-Term Safety Study Of Inhaled Insulin (CP-464,005, Inhaler) In Japanese Patients With Type1 or Type2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1

Japan
Olix Pharmaceuticals, Inc.
Trial Runners, LLC

Recruiting

Evaluation of OLX10212 in Patients With Neovascular Age-related Macular Degeneration

Neovascular Age-related Macular Degeneration

United States
Prisma Health-Upstate
AstraZeneca; MedImmune LLC

Recruiting

Durvalumab in Combination With Tremelimumab in Subjects With Advanced Rare Solid Tumors

Cancer | Rare Disease

United States
Olix Pharmaceuticals, Inc.
Alira Health

Completed

Study to Evaluate Efficacy of OLX10010 in Reducing Recurrence of Hypertrophic Scarring After Scar Revision Surgery

Hypertrophic Scar

United States
Azienda Ospedaliera Città della Salute e della...

Completed

Standard or Convalescent Plasma in Patients With Recent Onset of COVID-19 Respiratory Failure (PLACO-COVID)

COVID-19

Italy
Emory University
AstraZeneca

Completed

Tremelimumab and Durvalumab With or Without Radiation Therapy in Patients With Relapsed Small Cell Lung Cancer

Recurrent Small Cell Lung Carcinoma

United States
Pfizer

Terminated

A Pharmacokinetic And QT Study Of CP-751,871 In Healthy Subjects

Healthy Volunteers

United States
Jonsson Comprehensive Cancer Center
AstraZeneca

Active, not recruiting

Radiation Therapy and Durvalumab With or Without Tremelimumab in Treating Participants With Unresectable, Locally Advanced, or Metastatic Bladder Cancer

Stage IV Bladder Cancer AJCC v8 | Stage IVA Bladder Cancer AJCC v8 | Stage IVB Bladder Cancer AJCC v8 | Bladder Urothelial Carcinoma

United States
Jonsson Comprehensive Cancer Center
AstraZeneca

Active, not recruiting

Brachytherapy With Durvalumab or Tremelimumab for the Treatment of Patients With Platinum-Resistant, Refractory, Recurrent, or Metastatic Gynecological Malignancies

Metastatic Malignant Female Reproductive System Neoplasm | Platinum-Resistant Malignant Female Reproductive System Neoplasm | Recurrent Malignant Female Reproductive System Neoplasm | Refractory Malignant Female Reproductive System Neoplasm

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Qualitative Study on the Perception of Changes in the Psychotherapy of Traumatized Young People (TRAUMADOPSY)

Post-traumatic Stress Disorder

France
Maastricht University Medical Center
Erasmus Medical Center; Jules Bordet Institute; Academisch Ziekenhuis Maastricht

Recruiting

Phase 1/2 Clinical Trial of CP-506 (HAP) in Monotherapy or With Carboplatin or ICI

Unspecified Adult Solid Tumor, Protocol Specific

Netherlands, Belgium
National Cancer Institute (NCI)

Active, not recruiting

Erlotinib Hydrochloride and Onalespib Lactate in Treating Patients With Recurrent or Metastatic EGFR-Mutant Non-small Cell Lung Cancer

Recurrent Lung Non-Small Cell Carcinoma | Stage IV Lung Non-Small Cell Cancer AJCC v7

United States
University Hospital, Bordeaux
Ministry for Health and Solidarity, France

Completed

Total Disc Replacement Versus Anterior Cervical Decompression and Fusion (CERVIDISC)

Cervical Degenerative Disc Disease

France
VA Office of Research and Development

Completed

Brief Cognitive Behavioral Therapy for Chronic Pain

Musculoskeletal Pain | Chronic Pain

United States
Assiut University

Not yet recruiting

Effect of Magnesium Sulphate Pretreatment in Pediatric Laparoscopy (MgSO4/MR)

Muscle Relaxation

Egypt
Virginia Commonwealth University

Recruiting

Decreasing Long-term Opioid Use in Cancer Survivors

Pain | Chronic Pain | Cancer Pain | Survivorship

United States
Pfizer

Completed

A Study Of 6-Month Duration To Evaluate The Weight Loss Effect Of Various Doses Of CP-945,598 In Obese Subjects

Obesity

United States
Northwestern University
University of Chicago; University of Illinois at Chicago; Shirley Ryan AbilityLab

Active, not recruiting

Bilateral Priming Plus Task Specific Training for Severe Upper Limb Hemiparesis

Stroke

United States
Pfizer

Withdrawn

Effects of Fenofibrate on the Safety, Toleration and Efficacy Biomarkers of CP-742,033

Obesity
University of Colorado, Denver

Recruiting

Acceptability and Efficacy of Pain Reprocessing Therapy in Racially/ Ethnically Diverse Adults With Chronic Back Pain

Back Pain | Pain, Chronic

United States

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