Search clinical trials for: calcineurin inhibitor

Total 64421 results

Hospital Universitari de Bellvitge

Completed

Conversion Pharmacodynamic Study in Stable Renal Transplant Patients Receiving Tacrolimus Two Times a Day to a New Formulation of Tacrolimus - LCP Tacro - 1 Time a Day. (TACPKPD)

Kidney Transplant; Complications

Spain
Santen SAS

Completed

NOVA22007 0.05% and 0.1% Cyclosporine Versus Vehicle for the Treatment of Dry Eye

Dry Eye

United States
Veloxis Pharmaceuticals
PPD

Completed

Safety and Efficacy of LCP-Tacro™ Once Daily in Stable Renal Transplant Patients Converted From Prograf® Twice Daily

Renal Failure

United States
Veloxis Pharmaceuticals
CTI Clinical Trial and Consulting Services; Aptuit

Completed

Pharmacokinetics of LCP-Tacro(TM) Once Daily And Prograf® Twice A Day in Adult De Novo Kidney Transplant Patients

Renal Failure | Kidney Failure

United States
Imam Khomeini Hospital

Completed

Comparisone of Iminoral Versus Neoral in Prevention of Acute Rejection in Renal Transplantation

End Stage Renal Disease | Renal Transplantation

Iran, Islamic Republic of
Ophthalmic Consultants of Long Island
Allergan

Completed

Efficacy of Topical Cyclosporin for Ocular Rosacea

Rosacea

United States
Samsung Medical Center

Completed

Randomized Trial of Cyclosporine and Tacrolimus Therapy With Steroid Withdrawal in Living-Donor Renal Transplantation

Kidney Transplantation | Living Donors

Korea, Republic of
Novartis

Completed

Conversion From Tacrolimus to Cyclosporine Microemulsion in Liver Transplant Patients With New Onset Diabetes After the 3rd Month Post-transplant

Maintenance Liver Transplant Patients With New Onset Diabetes
Santen SAS

Completed

Double-Masked Trial of NOVA22007 (Ciclosporin 0.1%) Versus Vehicle in Patients With Moderate to Severe Dry Eye Syndrome

Moderate to Severe Dry Eye Syndrome

France
Shahid Beheshti University of Medical Sciences

Completed

Efficacy of Topical Cyclosporine A for Treatment and Prevention of Graft Rejection in Corneal Grafts With Previous Rejection Episodes

Endothelial Graft Rejection

Iran, Islamic Republic of
University Hospital Birmingham
Novartis

Unknown

Calcineurin Inhibitor Minimisation in Renal Transplant Recipients With Stable Allograft Function (CNIM-SRT)

Chronic Allograft Nephropathy

United Kingdom
National Eye Institute (NEI)

Completed

Treatment of Dry Eye Syndrome With Cyclosporin A Eye Drops

Keratoconjunctivitis Sicca | Sjogren's Syndrome

United States
Bing Han

Not yet recruiting

Efficacy and Safety in Transfusion Independent Non-severe Aplastic Anemia

Aplastic Anemia

China
Chang Gung Memorial Hospital
Ministry of Science and Technology, Taiwan

Completed

Comparison of Lindioil (Indigo Naturalis Oil Extract) Ointment to Protopic® Ointment 0.1% in Treating Atopic Dermatitis

Atopic Dermatitis

Taiwan
Santen SAS

Completed

Double-Masked Trial of NOVA22007 (1mg/mL Ciclosporin/Cyclosporine) Versus Vehicle in Pediatric Patients With Active Severe Vernal Keratoconjunctivitis

Vernal Keratoconjunctivitis

United States, Croatia, France, Germany, Greece, Hungary, India, Israel, Italy, Portugal, Spain
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Horse ATG/CsA in Aplastic Anemia Patients Unresponsive to or With a Suboptimal Response to Rabbit ATG/CsA Treatment

Anemia, Aplastic | Anemia, Hypoplastic

United States
Astellas Pharma Europe Ltd.

Completed

Study to Ascertain if Prolonged Release Tacrolimus (FK506E - MR4) is Safe and Effective When Used in the Long Term and in Combination With Other Immunosuppressive Drugs in Patients Who Have Received a Transplant

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Spain, Australia, France, Germany, Canada, Italy, United Kingdom, Belgium, South Africa, Switzerland, Sweden, United States, Austria, Brazil, Czechia, Denmark, Finland, Hungary, Ireland, Mexico, Netherlands, New Zealand, Poland
DH Bio Co., Ltd.
BTO Pharm. Co., Ltd.

Completed

Efficacy and Safety Study of Haporine-S for Treatment of Moderate to Severe Dry Eye Syndromes

Dry Eye Syndromes

Korea, Republic of
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cyclosporine Inhalation Solution (CIS) in Lung Transplant and Hematopoietic Stem Cell Transplant Recipients for the Treatment of Bronchiolitis Obliterans Syndrome

Bronchiolitis Obliterans | Graft vs Host Disease | Constrictive Bronchiolitis | Bronchiolitis, Exudative | Bronchiolitis, Proliferative

United States
Huons Co., Ltd.

Completed

Efficacy and Safety of HU007 Eye Drops in Patients With Dry Eye Syndrome

Dry Eye Syndrome

Korea, Republic of
Astellas Pharma China, Inc.

Terminated

A Study to Evaluate the Efficacy and Safety in Kidney Transplant Recipients When Changed From Cyclosporine to Tacrolimus Prolonged-release Capsule or Tacrolimus Capsule

Kidney Transplant Recipients

China
University of Colorado, Denver
American Heart Association

Terminated

Clinical Pharmacology of Aliskiren in Combination With Cyclosporine in Cardiac Transplantation

Hypertension | Cardiac Transplantation

United States
Hospices Civils de Lyon

Completed

Does Cyclosporine ImpRove Clinical oUtcome in ST Elevation Myocardial Infarction Patients at 3 Years of Follow-up. CIRCUS II Study (CIRCUS II)

ST Elevation Acute Myocardial Infarction

France
Astellas Pharma Inc
Astellas Pharma Canada, Inc.

Completed

Tacrolimus as Secondary Intervention vs. Continuation of Cyclosporine in Renal Transplant Patients With Chronic Renal Allograft Failure (CRAF)

Renal Transplantation | Chronic Renal Allograft Failure

Canada
Hospices Civils de Lyon

Completed

Cyclosporine A in Cardiac Arrest (CYRUS)

Non Shockable Out of Hospital Cardiac Arrest

France
APT Pharmaceuticals, Inc.

No longer available

Cyclosporine Inhalation Solution (CIS) in Lung Transplant Recipients

Lung Transplant

United States
Rennes University Hospital
Novartis

Terminated

Switch From Tacrolimus to Cyclosporin in the Treatment of Recurrent Hepatitis C After Liver Transplantation

Chronic Hepatitis C | Evidence of Liver Transplantation

France
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Cyclosporine A Microemulsion in Maintenance Patients With Chronic Plaque Psoriasis

Chronic Plaque Psoriasis

Italy
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Medical Treatment for Diamond Blackfan Anemia

Hematologic Disease | Fanconi's Anemia

United States
National Institutes of Health Clinical Center (CC)

Completed

A Randomized Trial of Antithymocyte Globulin Versus Cyclosporine to Treat the Cytopenia of Myelodysplastic Syndrome

Myelodysplastic Syndromes | Hematologic Diseases

United States
University of Nebraska
Genzyme, a Sanofi Company

Unknown

A Study of Thymoglobulin and Tacrolimus in Liver Transplant (thymo)

Liver Transplantation | Liver Disease | Immunosuppression

United States
Sociedad Andaluza de Trasplantes de Organos y Tejidos

Unknown

Renal Function Optimization With Mycophenolate Mofetil (MMF) Immunosuppressor Regimes (ALHAMBRA)

Kidney Diseases | Graft Rejection

Spain
Zhejiang University

Recruiting

Ruxolitinib With Calcineurin and Methotrexate vs. Calcineurin Plus Methotrexate and Mycophenolate Mofetil as Graft Versus Host Disease Prophylaxis for HLA-haploidentical Hematopoietic Stem Cell Transplantation

Graft Versus Host Disease

China
Bryan Burt, MD
Brigham and Women's Hospital

Completed

Cyclosporine For The Treatment Of COVID-19(+)

SARS (Disease)

United States
Boston Sight

Withdrawn

Novel Use of Restasis and PROSE Devices

Ocular Surface Disease

United States
Sight Sciences, Inc.

Active, not recruiting

Prospective, Randomized, Masked, Controlled Trial To Evaluate The Safety And Effectiveness Of The TearCare® System In The Treatment Of The Signs And Symptoms Of Dry Eye Disease (SAHARA)

Dry Eye | Meibomian Gland Dysfunction

United States
Samsung Medical Center

Completed

The Effect of Cyclosporin Before Cataract Surgery

Dry Eye Syndromes

Korea, Republic of
Atea Pharmaceuticals, Inc.
Hoffmann-La Roche

Completed

Effect of Cyclosporine on the Pharmacokinetics (PK) of AT-527 (R07496998)

Healthy Volunteer Study

Canada
Instituto de Seguridad y Servicios Sociales de...

Unknown

Cyclosporine A Plus Low-steroid Treatment in COVID-19 Pneumonia

COVID 19 Pneumonia

Mexico
RenJi Hospital

Unknown

Basiliximab Treating Interstitial Pneumonia of CADM

Dermatomyositis | Lung; Disease, Interstitial, With Fibrosis

China
The Cleveland Clinic
Pfizer

Terminated

Renal Allograft Function and Histology Following Switching From A Tacrolimus to Sirolimus (SRL)-Based Immunosuppression-

Kidney Transplant

United States
Innovative Medical

Completed

Efficacy and Safety of a New Multi-dose Lubricant Eye Drop Concomitant With Restasis® (Cyclosporine A) for the Treatment of Dry Eye Symptoms

Dry Eye

United States
PETHEMA Foundation

Completed

Antithymocyte Globulin and Cyclosporine in Treating Low Risk Patients With Myelodysplastic Syndrome

Myelodysplastic Syndrome

Spain
Peking Union Medical College Hospital

Not yet recruiting

Luspatercept Plus CsA vs CsA for the Treatment of Newly Diagnosed Non-Transfusion-Dependent NSAA

Aplastic Anemia

China
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

Safety and Effectiveness of Trappa Ethanolamine Tablets Combined With Ciclosporin in the Treatment of Primary Treatment of Non-severe Aplastic Anemia

Non-severe Aplastic Anemia

China
HK inno.N Corporation

Not yet recruiting

A Study to Evaluate Effect of IN-A001 on Pharmacokinetics of Tacrolimus in Healthy Volunteers

Healthy

Korea, Republic of
Pavly Moawd

Completed

Comparing Effect of Topical Tacrolimus 0.03% Versus Cyclosporine 0.05% in Dry Eyes of Secondary Sjogren Syndrome

Dry Eye | Sjogren Syndrome

Egypt
Allergan

Completed

Physician's Evaluation of Cyclosporine Ophthalmic Emulsion 0.05%

Dry Eye Disease

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Completed

Cyclosporine Eye Drops in Preventing Graft-Versus-Host Disease of the Eye in Patients Who Have Undergone Donor Stem Cell Transplant for Hematologic Cancer or Bone Marrow Failure Disorder

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Graft Versus Host Disease | Myelodysplastic/Myeloproliferative Neoplasms

United States
Guangdong Provincial People's Hospital

Unknown

Tacrolimus Combined With Entecavir on HBV Associated Glomerulonephritis(HBV-GN) (TOHBVGN)

Hepatitis B Virus Associated Nephrotic Syndrome

China

3

Subscribe