Search clinical trials for: caspofungin acetate

Total 4005 results

National Cancer Institute (NCI)

Completed

Caspofungin Acetate in Treating Children With Fever and Neutropenia

Sarcoma | Lymphoma | Kidney Cancer | Leukemia | Neutropenia | Neuroblastoma | Infection | Fever, Sweats, and Hot Flashes

United States
Merck Sharp & Dohme LLC

Completed

Open, Pharmacokinetic Study of Caspofungin in Neonates and Infants (0991-058)

Candidiasis
European Organisation for Research and Treatment...

Completed

Empirical Versus Preemptive Antifungal Therapy

Myelodysplastic Syndromes | Leukemia | Fungal Infection

Belgium, Netherlands, Germany, France, Czechia, Slovakia
European Organisation for Research and Treatment...

Completed

Caspofungin Acetate in Treating Aspergillosis in Patients With Hematologic Cancer or in Patients Who Have Undergone a Stem Cell Transplant

Cancer

France, Switzerland, Italy, Slovakia, Belgium, Germany, Turkey
Merck Sharp & Dohme LLC
Mycoses Study Group

Terminated

Pilot Feasibility Study With Patients Who Are at High Risk For Developing Invasive Candidiasis in a Critical Care Setting (MK-0991-067)

Invasive Candidiasis
Merck Sharp & Dohme LLC

Completed

A Study of Caspofungin Acetate (MK0991) for the Treatment of Esophageal Candidiasis or Invasive Candidiasis in Chinese Adults (MK-0991-066)

Fungal Infection
Merck Sharp & Dohme LLC

Completed

Open, Pharmacokinetic Study of Caspofungin Acetate in Immunocompromised Young Children With Febrile Neutropenia (0991-042)

Fungal Infection
Merck Sharp & Dohme LLC

Completed

A Clinical Study of MK0991 (Caspofungin) in Japanese Patients With Deep-seated Candida or Aspergillus Infections (0991-062)(COMPLETED)

Fungal Infection
Fujian Shengdi Pharmaceutical Co., Ltd.

Recruiting

A Trial of Intravenous HRS9432 in the Treatment of Subjects With Candidemia and/or Invasive Candidiasis

Patients With Candidemia and/or Invasive Candidiasis

China
Merck Sharp & Dohme LLC

Completed

A 28 - 90 Days Study to Evaluate the Safety, Tolerability, and Efficacy of Caspofungin Injection as Empirical Therapy in Indian Adults With Persistent Fever and Neutropenia (0991-053)(COMPLETED)

Fungal Infection
Merck Sharp & Dohme LLC

Completed

A Multicenter, Randomized, Double-Blind, Comparative Study to Evaluate the Safety, Tolerability, and Efficacy of 2 Dosing Regimens of an Antifungal Drug in the Treatment of Fungal Infections in Adults (0991-801)(COMPLETED)

Invasive Candidiasis
Merck Sharp & Dohme LLC

Completed

Documented Candida or Aspergillus Infections in Pediatric Patients (0991-043)

Candidiasis | Aspergillosis
Merck Sharp & Dohme LLC

Completed

Caspofungin for the Treatment of Non-blood Candida Infections (0991-045)

Candidiasis
Merck Sharp & Dohme LLC

Completed

Evaluate the Safety and Efficacy of Caspofungin Acetate as Empirical Therapy in Chinese Adults With Persistent Fever and Neutropenia (0991-055)

Fungal Infection
Shanghai General Hospital, Shanghai Jiao Tong University...

Not yet recruiting

To Evaluate the Efficacy and Safety of Micafungin in Preventing Invasive Mycosis After Liver Transplantation

Liver Transplantation
Merck Sharp & Dohme LLC

Completed

MK0991 Versus Amphotericin B for Empirical Therapy in Febrile, Neutropenic Pediatric Patients (0991-044)

Neutropenia | Fever
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment

Cancer

United States
Karolinska Institutet

Completed

Hemodynamic Effects of Cold Versus Warm Fluid Bolus

Temperature Change, Body | Hypovolemia

Sweden
Assistance Publique - Hôpitaux de Paris

Completed

Pharmacokinetics of Caspofungin in Burn Patients (Caspo-brûlés)

Thermal Injury

France
Starx Research Center, LLC

Unknown

Ocular Allergy Treatment Practical Impact Trial ((OAT-PIT))

Allergic Conjunctivitis | Rhinoconjunctivitis

United States
Cttq

Completed

Empiric Therapy of Patients With Persistent Fever and Agranulocytosis Using Caspofungin

Fungal Infection

China
Radboud University Medical Center

Completed

Pharmacokinetics of Caspofungin (Cancidas ®) Given Intravenously as Therapy to Patients With an Invasive Fungal Infection in the Intensive Care Unit - a Search for Co-variates (CASCADE)

Invasive Fungal Infection

Netherlands
Pfizer

Terminated

An Evaluation Of The Effectiveness And Safety Of Anidulafungin Compared To Caspofungin For The Treatment Of Deep Tissue Infection Due To Candida

Candidiasis | Fungemia

Belgium, United States, Canada, Switzerland, Netherlands, Bulgaria, Portugal, Romania, Russian Federation
University of Cologne

Completed

Caspofungin Maximum Tolerated Dose in Patients With Invasive Aspergillosis

Invasive Aspergillosis

Germany, Belgium
The First Affiliated Hospital of Guangzhou Medical...
Merck Sharp & Dohme LLC

Unknown

Efficacy and Safety of Caspofungin for Invasive Pulmonary Aspergillosis Underlying Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease | Invasive Pulmonary Aspergillosis

China
Werner J. Heinz
Merck Sharp & Dohme LLC

Completed

Pharmacokinetic, Safety and Efficacy of Intermittent Application of Caspofungin for Antifungal Prophylaxis (CASPHYLAX)

Fungal Infection

Germany
Merck Sharp & Dohme LLC

Completed

MK0991 in Combination With Standard Antifungal Agent(s) for the Treatment of Salvage Invasive Aspergillosis (0991-037)

Aspergillosis
Pfizer

Terminated

An Evaluation Of The Effectiveness And Safety Of Anidulafungin Compared To Caspofungin For The Treatment Of Serious Fungal Infection Due To Candida In Patients With A Dysfunctional Immune System

Candidiasis | Fungemia | Neutropenia

Poland, Russian Federation, France, Bosnia and Herzegovina, Italy, Slovakia
Shanghai Jiao Tong University School of Medicine

Unknown

Caspofungin Based Combined Anti-fungal Therapy for Proven or Probable Invasive Fungal Infection

Leukemia | Transplantation, Hematopoietic Stem Cell

China
Erasme University Hospital

Completed

Pharmacokinetics of Caspofungin After One Dose in Patients With Liver Failure

Bacterial Infections and Mycoses | Liver Disease

Belgium
Astellas Pharma Inc

Completed

Trial of Two Dosing Regimens of Micafungin Versus Caspofungin for the Treatment of Esophageal Candidiasis

Candidiasis, Oral

Argentina, South Africa, Brazil, Peru
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Terminated

Voriconazole and Caspofungin Acetate in Treating Invasive Fungal Infections in Patients With Weakened Immune Systems

Unspecified Adult Solid Tumor, Protocol Specific | Infection

United States
Centre Hospitalier Universitaire de Nīmes

Completed

Pharmacokinetic Study on Echinocandins for Patients With Septic Shock Following Secondary Peritonitis

Septic Shock | Peritonitis

France, Australia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemotherapy for Acute Myeloid Leukemia

Acute Myeloid Leukemia | Recurrent Adult Acute Myeloid Leukemia | Fungal Infection | Neutropenia | Secondary Acute Myeloid Leukemia | Untreated Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia in Remission | Childhood Acute Myeloid Leukemia in Remission | Recurrent Childhood Acute Myeloid... and other conditions

United States, Canada, Puerto Rico
Universitair Ziekenhuis Brussel

Completed

Initiation of Ovarian Stimulation With Recombinant-human FSH (Bemfola®) in the Late Follicular Phase

Infertility, Female

Belgium
Joachim Zdolsek

Recruiting

Fluid Challenge and Plasma Volume, During Surgery (FC-VE)

Gynecologic Cancer | Colorectal Cancer | Colorectal Disorders | Urologic Cancer | Benign Neoplasm

Sweden
Gilead Sciences

Completed

COMBISTRAT: AmBisome® in Combination With Caspofungin for the Treatment of Invasive Aspergillosis

Invasive Aspergillosis

France
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Caspofungin Acetate, Fluconazole, or Voriconazole in Preventing Fungal Infections in Patients Following Donor Stem Cell Transplant

Hematopoietic and Lymphoid Cell Neoplasm | Fungal Infection

United States, Canada
University Hospital Muenster
Merck Sharp & Dohme LLC; Gilead Sciences

Completed

A Study of Caspofungin, Liposomal Amphotericin B or the Combination of Both for Patients After Stem-Cell Transplantation

Hematopoietic Stem Cell Transplantation | Fungus Diseases

Germany
Centre Hospitalier Universitaire de Saint Etienne
Merck Sharp & Dohme LLC

Completed

Evaluation of the Pharmacokinetics of Caspofungin in ICU Patients (CaspoKin)

Shock

France
Shandong University

Completed

Population Pharmacokinetics and Dose Optimization of Caspofungin in Adolescents

Invasive Fungal Infections

China
Texas Tech University Health Sciences Center
University of Texas Southwestern Medical Center; National Center for Research...

Completed

Effect of Weight and/or Obesity on Caspofungin Drug Concentrations

Obesity | Fungal Infection

United States
Wendell Yap, MD
University of Kansas Medical Center

No longer available

Clinical Management Decisions for Recurrent Prostate Cancer Patients Based on [11C]Acetate PET Scan

Prostate Cancer

United States
Children's Hospital of Fudan University

Not yet recruiting

PK/PD of Caspofungin in Children Severe Infection

Pharmacokinetics | Infection, Fungal

China
Medical University of Lublin

Unknown

Pharmacokinetics of Caspofungin

Critical Illness | Septic Shock | Fungal Infection
National Cancer Institute (NCI)

Completed

Caspofungin to Prevent Candidiasis in Adults in Hospital Intensive Care Units

Candidiasis

United States
University of Michigan
National Institutes of Health (NIH)

Completed

The Impact of Zinc Supplementation on Left Ventricular Function in Nonischemic Cardiomyopathy

Heart Failure | Cardiomyopathies

United States
Merck Sharp & Dohme LLC

Completed

A Study of the Side Effects of L-743,872 in Men With Candidal Esophagitis

HIV Infections | Candidiasis, Esophageal

United States
University Medical Center Groningen

Completed

Optimal Dosage of Caspofungin in Critically Ill Patients

Critically Ill | Suspected Invasive Candidiasis

Netherlands
Azienda Ospedaliera di Padova
Merck Sharp & Dohme LLC

Unknown

Caspofungin as Prophylaxis in High Risk Liver Transplantation Recipients (CPHRLTX)

Mycoses | Fungemia

Italy

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