Search clinical trials for: Chemoradiotherapy Temozolomide

Total 1164 results

Biotech Pharmaceutical Co., Ltd.

Completed

A Real-world Study of the Efficacy and Safety of Nimotuzumab in Combination With Chemoradiotherapy for LASCCHN (Redbull-1)

Locally Advanced Head and Neck Squamous Cell Carcinoma

China
Yonsei University

Completed

Durvalumab (MEDI4736) and Tremelimumab in Hormone Receptor-positive, Hypermutated Metastatic Breast Cancer Identified by Whole Exome Sequencing

Metastatic Breast Cancer

Korea, Republic of
Second Affiliated Hospital, School of Medicine,...

Unknown

A Multicenter, Prospective, Phase III Randomized Controlled Clinical Study for the Treatment of N2-3 Nasopharyngeal Carcinoma Patients

Nasopharyngeal Carcinoma | Neoadjuvant Chemotherapy

China
Sun Yat-sen University
Guangdong Provincial People's Hospital; Affiliated Cancer Hospital of Shantou... and other collaborators

Unknown

A Multicenter Trial Comparing Multi-course Chemotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma

China
University Hospital, Antwerp

Recruiting

Adjuvant Dendritic Cell-immunotherapy Plus Temozolomide in Glioblastoma Patients (ADDIT-GLIO)

Glioblastoma Multiforme of Brain

Belgium
Monteris Medical

Terminated

Feasibility Study on LITT for Newly Diagnosed Glioblastoma (FLAG)

Glioblastoma

United States
Grupo Español de Investigación en Neurooncología

Completed

Glasdegib (PF-04449913) With Temozolomide Newly Diagnosed Glioblastoma (GEINOGLAS)

Glioblastoma

Spain
Orphelia Pharma
ClinSearch

Active, not recruiting

TEMOkids Study : A Phase I Pediatric Study for KIMOZO, Oral Suspension of Temozolomide

Pediatric Cancer

United Kingdom, France, Spain, Germany, Netherlands
Xue Xiaoying

Completed

Treatment of High-grade Gliomas Using Hypofractionated Radiation Therapy -a Phase I Clinical Trial

Glioma | Radiotherapy, Intensity-Modulated | Maximum Tolerated Dose
Exelixis

Completed

Safety Study of XL184 (Cabozantinib) in Combination With Temozolomide and Radiation Therapy in the Initial Treatment of Adults With Glioblastoma

Glioblastoma | Gliosarcoma | Giant Cell Glioblastoma

United States
Yong Chen

Not yet recruiting

The Efficacy and Safety of Neoadjuvant Toripalimab Combined With Temozolomide in Resectable Stage III Melanoma

Melanoma Stage III

China
John Flickinger

Active, not recruiting

Short Course Chemo-Radiation Therapy for Patients With Newly Diagnosed Glioblastoma

Glioblastoma

United States
Orphelia Pharma

Completed

Bioequivalence Study Between Temozolomide Oral Suspension (Ped-TMZ) and Temodal® Capsules

Therapeutic Equivalency

France
Sidney Kimmel Comprehensive Cancer Center at Johns...

Completed

5 Fraction Stereotactic Radiosurgery With Temozolomide for Glioblastoma Multiforme

Glioblastoma Multiforme

United States
University of Florida
NovoCure Ltd.

Terminated

FORWARD Optune and Adjuvant TMZ in Grade II/III Astrocytoma (FORWARD)

Astrocytoma, Grade III | Astrocytoma, Grade II

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Temozolomide Plus Radiation Therapy in Treating Patients With Newly Diagnosed Anaplastic Oligodendrogliomas or Mixed Anaplastic Oligoastrocytomas

Brain and Central Nervous System Tumors

Canada, United States
NYU Langone Health
National Cancer Institute (NCI)

Withdrawn

Carboplatin, Temozolomide, and Filgrastim in Treating Patients With Newly Diagnosed or Recurrent High-Grade Glioma

Brain and Central Nervous System Tumors

United States
Prof. Dr. Wolfgang Wick
Essex Pharma GmbH

Completed

Comparison of Two Dosing Regimens of Temozolomide in Patients With Progressive or Recurrent Glioblastoma (DIRECTOR)

Glioblastoma

Germany, Austria, Switzerland
Barretos Cancer Hospital

Completed

Induction Chemotherapy for Advanced Head and Neck Cancer

Head and Neck Cancer

Brazil
National Cancer Institute (NCI)

Completed

Tremelimumab With Chemoembolization or Ablation for Liver Cancer

Hepatocellular Carcinoma | Biliary Tract Neoplasms | Liver Cancer | Biliary Cancer | Heptocellular Cancer

United States
Wuhan Union Hospital, China

Not yet recruiting

Neoadjuvant PD-1 Inhibitor Combined With Cetuximab in Operable Locally Advanced HNSCC (PC-1)

Head and Neck Squamous Cell Carcinoma | Neoadjuvant Therapy

China
Catharina Ziekenhuis Eindhoven

Recruiting

Induction Chemotherapy for Locally Recurrent Rectal Cancer (PelvEx II)

Recurrent Rectal Cancer

Netherlands, Sweden, Belgium, Norway, Portugal
BeiGene

Completed

Study of Ociperlimab Plus Tislelizumab Plus Chemoradiotherapy in Participants With Untreated Limited-Stage Small Cell Lung Cancer

Limited Stage Small Cell Lung Cancer

China, Korea, Republic of, United States
Dushu Lake Hospital Affiliated to Soochow University

Recruiting

Natural Killer (NK) Cells (XS005) Injection Combined With Stupp Regimen for Adjuvant Chemotherapy in Subjects With Primary Glioblastoma(GBM)

Glioblastoma | GBM

China
Grupo Español de Investigación en Neurooncología
Tilray; Medical Cannabis Bike Tour; Voices Against Brain Cancer

Recruiting

TN-TC11G (THC+CBD) Combination With Temozolomide and Radiotherapy in Patients With Newly-diagnosed Glioblastoma (GEINOCANN)

Glioblastoma

Spain
M.D. Anderson Cancer Center

Completed

Temozolomide and SCH66336 for Recurrent Glioblastoma Multiforme

Glioblastoma Multiforme

United States
Methodist Healthcare

Terminated

Radiation Boost for Newly Diagnosed Glioblastoma Multiforme

Glioblastoma Multiforme

United States
Yunnan Cancer Hospital
Beijing Bethune Charitable Foundation

Recruiting

Single-arm, Single-center, Exploratory Phase II Clinical Study of Envafolimab Combined With Chemoradiotherapy in the Treatment of Locally Advanced pMMR/MSS Rectal Cancer (ESTIMATE)

Envafolimab Combined With Chemoradiotherapy in the Treatment of Locally Advanced pMMR/MSS Rectal Cancer

China
Cairo University
National Cancer Institute, Egypt

Unknown

Prevention of Oral Mucositis After Using Chamomile Oral Cryotherapy Versus Oral Cryotherapy in Pediatric Cancer Patients Receiving Chemotherapy.

Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy

Egypt
AHS Cancer Control Alberta

Recruiting

Chemoradiotherapy Versus Biomarker-Guided Therapy for Elderly and Frail GBM Patients

Glioblastoma Multiforme

Canada
SCRI Development Innovations, LLC
Genentech, Inc.

Terminated

Study of High-Dose Rituximab With Temozolomide as Treatment for Primary Central Nervous System (CNS) Lymphoma

Primary Central Nervous System Lymphoma

United States
Peking Union Medical College Hospital

Not yet recruiting

The Effect of Chemoradiotherapy in Patients With Refractory Pituitary Adenomas

Pituitary Adenomas
Case Comprehensive Cancer Center

Active, not recruiting

Ibrutinib With Radiation and Temozolomide in Patients With Newly Diagnosed Glioblastoma

Glioblastoma

United States
Ohio State University Comprehensive Cancer Center

Completed

Carboplatin and Temozolomide (Temodar) for Recurrent and Symptomatic Residual Brain Metastases

Brain Tumor | Brain Metastases

United States
Mayo Clinic
National Cancer Institute (NCI)

Withdrawn

Vandetanib and Temozolomide in Treating Patients With Advanced Solid Tumors That Cannot Be Removed By Surgery

Unspecified Adult Solid Tumor, Protocol Specific
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Bortezomib and Temozolomide in Treating Patients With Brain Tumors or Other Solid Tumors That Have Not Responded to Treatment

Lymphoma | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer

United States
University of Michigan Rogel Cancer Center

Recruiting

Multiparametric MR-Guided High Dose Adaptive Radiotherapy With Concurrent Temozolomide in Patients With Newly Diagnosed Glioblastoma

Glioblastoma

United States
National Cancer Institute (NCI)

Completed

Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma

Glioblastoma | Astrocytoma | Brain Tumor | Gliosarcoma | Astroglioma

United States
Huashan Hospital
Shandong Provincial Hospital

Unknown

Gut Microbiota and Glioblastoma Multiforme Prognosis

Gut Microbiota, Glioblastoma Multiforme, Microglia, Tumor Related Macrophagocyte, Prognosis
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Terminated

Temozolomide During and After Radiation Therapy in Treating Patients Who Have Undergone Previous Surgery and Placement of Gliadel Wafers for Newly Diagnosed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Merck Sharp & Dohme LLC

Completed

Study of Temozolomide in Previously Untreated Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Participants With Low O6-Methylguanine Methyltransferase (MGMT) Expression (P05052) (TALL)

Myelodysplastic Syndrome | Leukemia, Acute Myeloid
European Organisation for Research and Treatment...

Unknown

Lonafarnib and Temozolomide in Treating Patients With Recurrent Primary Supratentorial Gliomas

Brain and Central Nervous System Tumors

Switzerland, France
Centre Leon Berard

Completed

Standard Radiation Therapy, Higher-Dose Radiation Therapy, or Chemotherapy in Treating Older Patients With Glioblastoma Multiforme

Brain and Central Nervous System Tumors

France
Merck Sharp & Dohme LLC

Completed

Temozolomide All-Case-Registered Surveillance (Designated Drug Use Investigation)(Study P05062)

Glioma | Astrocytoma
Assistance Publique - Hôpitaux de Paris

Recruiting

Innovative SonoCloud-9 Device for Blood Brain Barrier Opening in First Line Temozolomide Glioblastoma Patients. (SonoFIRST)

Initial Radiological Diagnosis Eligible for Tumor Resection | Initial Radiological Diagnosis Compatible With Newly Diagnosed Glioblastoma (IDH Wild-type) | Eligible for the Standard of Care Including Concurrent Temoradiation and Adjuvant Temozolomide

Belgium, France, Switzerland
Center Trials & Treatment Europe

Completed

Evaluate the Safety and Effectiveness of Intranasal Administration of Temozolomide in Patients With Glioblastoma

Gliosarcoma | Glioma, Malignant | Astrocytoma of Brain

Georgia, Bosnia and Herzegovina, Bulgaria
Massachusetts General Hospital
National Cancer Institute (NCI)

Terminated

MRI Scans in Evaluating the Effects of Radiation Therapy and Chemotherapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic Glioma

Brain and Central Nervous System Tumors

United States
WuHui

Unknown

Clinical Study of Apatinib Combined With Temozolomide in the Treatment of Uncontrolled or Repeated High-grade Gliomas

High-grade Gliomas

China
Oslo University Hospital

Recruiting

Dendritic Cell Immunotherapy Against Cancer Stem Cells in Glioblastoma Patients Receiving Standard Therapy (DEN-STEM)

Glioblastoma

Norway
Jonsson Comprehensive Cancer Center
Millennium Pharmaceuticals, Inc.

Completed

Bortezomib, Temozolomide, and Regional Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Gliosarcoma

Brain and Central Nervous System Tumors

United States

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