Search clinical trials for: Chloroquine Primaquine

Total 270 results

University of Oxford
Mahidol University; Indonesia-MoH

Completed

Study of ACTs Plus Primaquine for Uncomplicated Plasmodium Vivax Malaria (ACTPQ)

Vivax Malaria

Indonesia
University of Oxford

Completed

Pharmacokinetic Study of Primaquine and Pyronaridine-Artesunate in Healthy Subjects

Healthy

Thailand
Fundação de Medicina Tropical Dr. Heitor Vieira...

Completed

Chloroquine Diphosphate in the Prevention of SARS in Covid-19 Infection (CloroCOVID19II)

COVID-19 | SARS-CoV Infection | Clinical Trial | Severe Acute Respiratory Syndrome (SARS) Pneumonia

Brazil
London School of Hygiene and Tropical Medicine
Radboud University Medical Center; Centre national de recherche et de formation...

Completed

Low Dose Primaquine for Clearance of Gametocytes (LOPRIM)

Malaria | Plasmodium Falciparum | Asymptomatic Malaria

Burkina Faso
University of Oxford

Completed

Pharmacokinetic and in Vitro Transmission Blocking Activities Study of Primaquine Compare to Methylene Blue in Healthy Volunteer Both G6PD Normal and G6PD Deficiency

Healthy | G6PD Normal | G6PD Deficient

Thailand
Muhimbili University of Health and Allied Sciences
Karolinska Institutet; Uppsala University; The University of Western Australia

Completed

"Prolonging the Therapeutic Life Span of Artemisinin-based Combination Therapies (ACT) in Bagamoyo District, Tanzania" (ALU-PQ)

Malaria,Falciparum

Tanzania
HaEmek Medical Center, Israel
T MAY BIOPHARMA LTD.

Terminated

Chloroquine for Mild Symptomatic and Asymptomatic COVID-19

COVID-19

Israel
London School of Hygiene and Tropical Medicine
University Medical Center Nijmegen; Centre national de recherche et de formation...

Completed

Safety of Primaquine + Artemether-lumefantrine in G6PD Deficient Males With an Asymptomatic Malaria Infection (SAFEPRIM)

Malaria

Burkina Faso
Bandim Health Project

Completed

Pharmacokinetic Study of Multi-dose Chloroquine

Malaria

Guinea-Bissau
Tanta University

Completed

Zinc With Chloroquine/Hydroxychloroquine in Treatment of COVID-19

COVID

Egypt
Maastricht Radiation Oncology
National Cancer Institute (NCI); Maastricht University Medical Center

Terminated

Chloroquine as an Anti-Autophagy Drug in Stage IV Small Cell Lung Cancer (SCLC) Patients (Chloroquine IV)

Small Cell Lung Cancer

Netherlands
Indonesia University
Walter and Eliza Hall Institute of Medical Research

Completed

Surveillance and Treatment With Dihydroartemisinin-piperaquine Plus Primaquine

Malaria

Indonesia
Bandim Health Project

Completed

Chloroquine and Amodiaquine for Treatment of Malaria in Children

Malaria, Falciparum

Guinea-Bissau
Kilimanjaro Clinical Research Institute
London School of Hygiene and Tropical Medicine; Ifakara Health Institute

Unknown

The Optimal Timing Of Primaquine To Prevent Malaria Transmission After Artemisinin-Combination Therapy

Malaria Transmission

Tanzania
Indonesia University

Completed

Impact of Dihydroartemisinin-piperaquine Plus Primaquine on Malaria Transmission in Lampung Province, Sumatra

Malaria

Indonesia
Indonesia University

Completed

Dihydroartemisinin-piperaquine and Primaquine for Uncomplicated Plasmodium Falciparum Cases (DHP+PQ)

Malaria

Indonesia
Sanaria Inc.
Indonesia University; Congressionally Directed Medical Research Programs; Eijkman...

Recruiting

Safety, Tolerability, Immunogenicity and Protective Efficacy of PfSPZ Vaccine and PfSPZ-CVac in Indonesian Adults Against Naturally-Transmitted Malaria

Malaria

Indonesia
Tanta University

Completed

Efficacay of Chloroquine or Hydroxychloroquine in COVID-19 Treatment

COVID-19 | Coronavirus Infection

Egypt
Pfizer

Completed

A Phase 1 Study To Estimate The Relative Bioavailability Of Fixed Combination Tablets Of Azithromycin And Chloroquine Compared To Co-Administered Individual Tablets Of Azithromycin And Chloroquine (AZCQ)

Malaria

United States
Tulane University Health Sciences Center
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Studies of AQ-13, a Candidate Aminoquinoline Antimalarial, in Comparison With Chloroquine

Malaria

United States
Pyae Linn Aung
University of South Florida; Mahidol University

Active, not recruiting

Efficacy of Focal Primaquine Mass Administration for Eliminating Plasmodium Vivax Malaria in Northern Myanmar

Malaria | Plasmodium Vivax | Myanmar | Mass Drug Administration | Primaquine

Myanmar
Tropical Pesticides Research Institute, Tanzania
European and Developing Countries Clinical Trials Partnership (EDCTP)

Completed

Single Low-dose Primaquine Efficacy and Safety. (ESSLDPQP4502D6)

Malaria

Tanzania
University of California, San Francisco
Radboud University Medical Center; Bill and Melinda Gates Foundation; Malaria... and other collaborators

Completed

Determining a Tolerable Dose of Primaquine in G6PD-deficient Persons Without Malaria in Mali (PQSAFETY)

Malaria

Mali
Walter Reed Army Institute of Research (WRAIR)

Completed

A Test to Predict the Hemolytic Potential of Drugs in G6PD Deficiency

Glucosephosphate Dehydrogenase Deficiency | Favism

United States
Fundação de Medicina Tropical Dr. Heitor Vieira...
Marcus Vinícius Guimarães de Lacerda; Mayla Gabriela Silva Borba; Wuelton Marcelo... and other collaborators

Completed

Chloroquine Diphosphate for the Treatment of Severe Acute Respiratory Syndrome Secondary to SARS-CoV2 (CloroCOVID19)

SARS-CoV Infection | Severe Acute Respiratory Syndrome (SARS) Pneumonia

Brazil
Centro de Investigação em Saúde de Manhiça

Completed

Evaluating the Role of Chloroquine for Malaria Elimination (Cloroquina)

Malaria

Mozambique
National University Hospital, Singapore

Unknown

The Chloroquine for Influenza Prevention Trial (CHIP)

Influenza

Singapore
Washington University School of Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Chloroquine to Treat People With Metabolic Syndrome Aim2 (ARCH-MS) (ARCH-MS)

Hypertension | Overweight | Dyslipidemias | Prediabetic State | Metabolic Syndrome X

United States
Inova Health Care Services
United States Department of Defense; U.S. Army Medical Research and Development... and other collaborators

Completed

Study of the Efficacy of Chloroquine in the Treatment of Ductal Carcinoma in Situ (The PINC Trial)

Carcinoma, Intraductal, Noninfiltrating | DCIS | Ductal Carcinoma In Situ

United States
Pfizer

Completed

A Phase 1 Study To Estimate The Relative Bioavailability Of Co-Administered Formulations Of Azithromycin Microsphere And Chloroquine Test Formulation Compared With Co-Administered Immediate Release Individual Azithromycin And Chloroquine Tablets In Healthy Adult Subjects (AZCQ)

Malaria Prophylaxis

United States
Pfizer

Completed

A Three Day Trial of Azithromycin Plus Chloroquine for the Treatment of Uncomplicated Plasmodium Falciparum Malaria

Falciparum Malaria

Colombia, India
University of Oxford

Completed

Pharmacokinetic Study of Primaquine in Healthy Obese Thai Adult Subjects (PQ in Obese)

Obese

Thailand
GlaxoSmithKline
Medicines for Malaria Venture

Completed

Tafenoquine/Chloroquine DDI Study

Malaria

United States
University of South Florida

Recruiting

Chloroquine for Patients With Symptomatic Persistent Atrial Fibrillation: A Prospective Pilot Study

Atrial Fibrillation

United States
Oxford University Clinical Research Unit, Vietnam
National Hospital for Tropical Diseases, Hanoi, Vietnam; Ministry of Health... and other collaborators

Completed

The Vietnam Chloroquine Treatment on COVID-19 (VICO)

COVID-19 | SARS-CoV-2 Infection

Vietnam
Pfizer

Terminated

Evaluate Parasitological Clearance Rates And Pharmacokinetics Of The Combination Of Azithromycin And Chloroquine In Asymptomatic Pregnant Women With Falciparum Parasitemia In Africa

Asymptomatic Parasitemia In Pregnancy

Malawi, Benin, Kenya, Tanzania, Uganda
Pfizer

Completed

Azithromycin Plus Chloroquine Versus Mefloquine for the Treatment of Uncomplicated Malaria in Africa

Malaria, Falciparum

Mali, Zambia, Ghana, Uganda
University of Oxford
Mahidol Oxford Tropical Medicine Research Unit

Not yet recruiting

Postpartum Primaquine in Breast Milk (PBC)

Postpartum Women

Thailand
Walter Reed Army Institute of Research (WRAIR)

Completed

Genetic Variability in CYP2D6 in U.S Active Duty Population

Pharmacologic Action

United States
Wroclaw Medical University

Completed

Chloroquine as Antiviral Treatment in Coronavirus Infection 2020

COVID-19

Poland
CMN "20 de Noviembre"

Unknown

Chloroquine Phosphate Prophylactic Use in Health Personnel Exposed to COVID-19 Patients

COVID-19

Mexico
University of Minnesota
Minnesota Medical Foundation

Terminated

Investigating the Anti-Human Immunodeficiency Virus (HIV) & Anti-inflammatory Effect of Chloroquine

HIV Infections

United States
Beijing Chao Yang Hospital

Unknown

Clinical Trial of Favipiravir Tablets Combine With Chloroquine Phosphate in the Treatment of Novel Coronavirus Pneumonia

Novel Coronavirus Pnuemonia

China
Pfizer

Terminated

Azithromycin in Combination With Chloroquine Versus Chloroquine in the Eradication of Asymptomatic Plasmodium Falciparum

Malaria, Falciparum
University of Sao Paulo General Hospital

Completed

CHLOROQUINE FOR MAINTENANCE REMISSION OF AUTOIMMUNE HEPATITIS

Hepatitis, Autoimmune

Brazil
Asan Medical Center

Completed

Clinical Trial for Evaluation of Ethnic Differences in Pharmacokinetics of Chloroquine, an Anti-malarial Drug

Healthy Volunteers

Korea, Republic of
University of Alberta

Completed

IMPACT: IMPact of Antimalarials on Covid-19 Infections in RAPPORT (IMPACT)

Rheumatoid Arthritis | Psoriatic Arthritis | Covid-19 Infection | Hydroxychloroquine

Canada
Pfizer

Completed

Azithromycin Plus Chloroquine Versus Mefloquine In the Treatment of Uncomplicated P. Falciparum Malaria.

Malaria

Burkina Faso, Ghana, Kenya, Mali, Senegal, Zambia
Idorsia Pharmaceuticals Ltd.

Completed

Effect of ACT-451840 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy Subjects

Healthy Subjects

Australia
Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories...
AHEPA University Hospital; Sismanoglio General Hospital; Athens General Hospital... and other collaborators

Terminated

Chloroquine Phosphate Against Infection by the Novel Coronavirus SARS-CoV-2 (COVID-19): The HOPE Open-Label, Non Randomized Clinical Trial (HOPE)

Pneumonia, Viral | Covid-19

Greece

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