Search clinical trials for: Clemizole HCl

Total 2802 results

Epygenix

Completed

Study of Safety and Pharmacokinetics of Oral Doses of EPX-100 in Healthy Subjects.

Dravet Syndrome

United States
Epygenix
Forest Hills Lab; Liberyx Therapeutics

Recruiting

EPX-100 (Clemizole Hydrochloride) as Add-on Therapy to Control Convulsive Seizures in Patients With Dravet Syndrome (ARGUS)

Dravet Syndrome

United States, Canada, Spain, Georgia, Hungary
Eiger Group International, Inc.

Unknown

Clemizole HCl for Subjects With Hepatocellular Carcinoma

Hepatocellular Carcinoma

Turkey
Epygenix

Not yet recruiting

EPX-100 (Clemizole Hydrochloride) as Adjunctive Therapy in Children With Lennox Gastaut Syndrome (LGS)

Lennox Gastaut Syndrome
Eiger BioPharmaceuticals

Completed

Safety and Tolerability Study of Clemizole Hydrochloride to Treat Hepatitis C in Subjects Who Are Treatment-Naive (CLEAN-1)

Hepatitis C
University of Virginia
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Diabetes Closed-Loop Project 6 (DCLP6): Fully Automated Closed-Loop Control in Type 1 Diabetes Using Meal Anticipation

Type 1 Diabetes

United States
Rabin Medical Center
Medtronic; GIF

Completed

An Open-label, Two-center, Randomized, Cross-over Study to Evaluate the Safety and Efficacy of Glycemic Control Using Hybrid-closed Loop vs. Advanced Hybrid Closed-loop in Young Subjects With Type 1 Diabetes

Diabetes Mellitus, Type 1

Germany, Israel
Rabin Medical Center

Completed

Comparison of Two Closed-Loop Strategies for Glucose Control in Type 1 Diabetes The DREMED Trail- 2

Type 1 Diabetes

Israel
Universidad Complutense de Madrid

Completed

One- Versus Two-Stage Aesthetic Crown Lengthening

Patients in Need of Surgical CL in the Anterior Maxillary Sextant for Restorative Purposes
University of Kansas Medical Center
National Cancer Institute (NCI)

Completed

Acolbifene in Preventing Cancer in Premenopausal Women at High Risk of Breast Cancer

Breast Cancer

United States
Acologix, Inc.

Unknown

A Randomized-Withdrawal Phase 3 Study Evaluating the Safety and Efficacy of Oral Nalfurafine HCl (AC-820)in Subjects on Hemodialysis With Uremic Pruritus (Renal Itch) (AC120-8231)

Uremic Pruritus
Daiichi Sankyo, Inc.

Terminated

Randomized, Double-blind, Active-controlled, Study of Rivoglitazone in Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
BioCryst Pharmaceuticals

Completed

Phase II Study of Forodesine in Subjects With Chronic Lymphocytic Leukemia (CLL)

Chronic Lymphocytic Leukemia (CLL)

United States, Australia
Daiichi Sankyo Co., Ltd.

Completed

Placebo Controlled Dose-Response Study of Rivoglitazone in Type 2 Diabetes

Type 2 Diabetes

Japan
Daiichi Sankyo Co., Ltd.

Completed

Placebo and Active Comparator Controlled Dose Response Study of Rivoglitazone in Type 2 Diabetes (RAISE)

Type 2 Diabetes

China
Eli Lilly and Company

Completed

Enzastaurin as Second and Third-Line Treatment for Non-Small Cell Lung Cancer.

Non-Small-Cell Lung Carcinoma

United States
Helsinn Therapeutics (U.S.), Inc

Completed

Safety and Efficacy of Anamorelin HCl in Patients With Non-Small Cell Lung Cancer-Cachexia (ROMANA 2)

Non-Small Cell Lung Cancer | Cachexia

Poland, United States, Israel, Russian Federation, Hungary, Australia, United Kingdom
Helsinn Therapeutics (U.S.), Inc

Completed

Anamorelin HCl in the Treatment of Non-Small Cell Lung Cancer-Cachexia (NSCLC-C): An Extension Study (ROMANA 3)

Non-Small Cell Lung Cancer | Cachexia

Poland, Ukraine, United States, Belgium, Spain, Belarus, Slovenia, Serbia, Canada, Russian Federation, Australia, Hungary, Germany, Czechia, France, Israel, Italy
VA Office of Research and Development
Helsinn Therapeutics (U.S.), Inc

Terminated

The Role of Ghrelin in Cancer Cachexia

Cancer Cachexia

United States
Helsinn Therapeutics (U.S.), Inc

Completed

Safety and Efficacy of Anamorelin HCl in Patients With Non-Small Cell Lung Cancer-Cachexia (ROMANA 1)

Non-Small Cell Lung Cancer | Cachexia

United States, Poland, Ukraine, Belgium, Germany, Spain, Belarus, Slovenia, Serbia, Netherlands, Canada, Russian Federation, Hungary, Czechia, France, Italy
Eli Lilly and Company

Completed

Enzastaurin for Patients With Metastatic Colorectal Cancer

Colonic Neoplasms

Sweden, Denmark
Artax Biopharma Inc
Simbec Research

Completed

Potential Food Effect And Repeated Dosing of AX-024.HCl In Healthy Subjects

Healthy

United Kingdom
Helsinn Therapeutics (U.S.), Inc

Completed

Safety and Efficacy of RC-1291 HCl in Patients With Cancer Related Anorexia and Weight Loss

Cancer Cachexia

United States
Universal Enterprises

Unknown

Bioequivalence of Phenazopyridine HCl in Healthy Volunteers

Human Volunteers

Pakistan
Abide Therapeutics

Completed

Central Pain Study for ABX-1431

Multiple Sclerosis | Neuromyelitis Optica Spectrum Disorder | Transverse Myelitis | Longitudinally Extensive Transverse Myelitis

United Kingdom
Loyola University

Completed

CATHETER ANALGESIA TRIAL Phenazopyrdine vs. Placebo: a Randomized Controlled Trial (CATH)

Catheter-related Bladder Discomfort

United States
H. Lee Moffitt Cancer Center and Research Institute

Terminated

Phase II Study of Irinotecan HCI for Recurrent Anaplastic Astrocytomas, Mixed Malignant Gliomas, and Oligodendrogliomas

Glioma | Astrocytoma | Oligodendroglioma

United States
Centre Hospitalier Sud Francilien

Completed

Real-world Use of Hybrid Closed Loop in Adolescents and Young Adults 15-25 Years of Age With Type 1 Diabetes (BFHado)

Type1 Diabetes | Adolescents | Young Adults

France
Cortexyme Inc.

Completed

A Multiple Ascending Dose Study of COR388

Alzheimer Disease

United States
Dendreon

Completed

Dose Escalation Study of EC D-3263 HCl in Advanced Solid Tumors

Solid Tumors

United States
Stealth BioTherapeutics Inc.

Recruiting

ReNEW:Phase 3 Study of Efficacy, Safety & Pharmacokinetics of Subcutaneous Injections of Elamipretide in Subjects With Dry Age-Related Macular Degeneration (Dry AMD) (ReNEW)

Age-Related Macular Degeneration

United States
Amicus Therapeutics

Approved for marketing

Physician Initiated Expanded Access Request for Migalastat in Individual Patients With Fabry Disease

Fabry Disease

United States, Australia
Artax Biopharma Inc
Simbec Research; ORION Clinical Services; Packaging Coordinators Inc; Centro de...

Completed

Safety Study of Immune System Modulator for Autoimmune Diseases

Healthy Volunteers

United Kingdom
Helsinn Therapeutics (U.S.), Inc

Completed

Placebo Controlled, Randomized Safety and Efficacy Study of RC-1291 in Cancer Anorexia/Cachexia.

Cancer Cachexia

United States
University of Virginia
Juvenile Diabetes Research Foundation

Completed

Hybrid Closed-Loop Control With Smart Prandial Insulin Dosing in Type 1 Diabetes

Type 1 Diabetes

United States
Atacama Therapeutics

Completed

Exploratory Study to Assess the Efficacy and Safety of TC-5214 in the Treatment of Subjects With Palmar Hyperhidrosis

Palmar Hyperhidrosis

United States
Millendo Therapeutics US, Inc.

Terminated

A Study of ATR-101 for the Treatment of Endogenous Cushing's Syndrome

Cushing Syndrome

United States, United Kingdom
Telik

Completed

Study of TLK199 HCl Liposomes for Injection in Myelodysplastic Syndrome

Myelodysplastic Syndromes

United States
Helsinn Healthcare SA

Completed

A Study to Evaluate the Efficacy and Safety of Anamorelin HCl for the Treatment of Malignancy Associated Weight Loss and Anorexia in Adult Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)

Non Small Cell Lung Cancer | Cachexia; Cancer

United States, Croatia, Australia, Belgium, Russian Federation, Poland, Romania, Ukraine
Atacama Therapeutics

Active, not recruiting

Clinical Study to Assess the Efficacy and Safety of AT-5214 in the Treatment of Subjects With Palmar Hyperhidrosis

Hyperhidrosis | Palmar Hyperhidrosis

United States
Helsinn Therapeutics (U.S.), Inc

Completed

Dose Range Study of Anamorelin in Patients With Non-small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

United States, India
Amicus Therapeutics

Active, not recruiting

Safety, Pharmacodynamics, and Efficacy of Migalastat in Pediatric Subjects (Aged >12 Years) With Fabry Disease

Fabry Disease

United States, United Kingdom
Amicus Therapeutics

Completed

Safety and Pharmacokinetics of AT1001 (Migalastat HCl) in Healthy Subjects and Subjects With Impaired Renal Function

Fabry Disease

United States
Charleston Laboratories, Inc

Completed

A Study to Assess the Efficacy and Safety of Oral CL-H1T in the Treatment of Acute Migraine Pain

Pain | Nausea | Vomiting | Migraine | Aura

United States
iN Therapeutics Co., Ltd.

Recruiting

A MAD Study to Evaluate the Safety, Tolerability and PK/PD of iN1011-N17 in Healthy Volunteers and PHN Patients.

Pain | Osteoarthritis | Chronic Pain | Neuropathic Pain | Post Herpetic Neuralgia

Australia
Amicus Therapeutics

Recruiting

A Study to Evaluate Migalastat in Fabry Subjects With Amenable GLA Variant and Renal Disease

Fabry Disease

Spain, United States, Japan, Australia, France, Portugal
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Recruiting

Study of ZG0895.HCl in Patients With Advanced Solid Tumors

Advanced Solid Tumor

China
Amicus Therapeutics

Completed

Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of Migalastat in Pediatric Subjects (Aged 12 to <18 Years)

Fabry Disease

United Kingdom, United States
Edward Messing
Imagin Medical

Completed

Near Infrared Fluorescence Imaging for Bladder Cancer Detection

Bladder Cancer

United States
Telik

Completed

Study of Canfosfamide in Refractory or Relapsed Mantle Cell, Diffuse Large B Cell Lymphoma and Multiple Myeloma

Multiple Myeloma | B Cell Lymphoma | Mantle Cell Lymphoma

United States

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