Search clinical trials for: CliniMACS TCR α/β Reagent Kit and CliniMACS CD19

Total 29 results

Alice Bertaina

Recruiting

Stem Cell Transplant From Donors After Alpha Beta Cell Depletion in Children and Young Adults

Hematologic Diseases

United States
Neena Kapoor, M.D.

Not yet recruiting

TCRαβ/CD19 Depletion of Stem Cell Grafts for Transplant

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Hematologic Malignancy | Graft Vs Host Disease | Graft-versus-host-disease | Non-hematologic Malignancy
Miltenyi Biomedicine GmbH
City of Hope Comprehensive Cancer Center

Not yet recruiting

M-2018-334 in Hematological Malignancies (HAPLO2022)

Hematological Malignancies
Alice Bertaina
California Institute for Regenerative Medicine (CIRM)

Recruiting

Early Trial of Allogeneic Hematopoietic Stem Cell Transplantation for Patients Who Will Receive a Kidney Transplant From the Same Donor

CKD Stage 4 | Cystinosis | FSGS | SLE Nephritis | SIOD

United States
Victor Aquino

Temporarily not available

Treatment Use of the CliniMACS® CD34 TCR Alpha/Beta for Allogenic Transplant (Expanded Access Use)

Transplant-Related Disorder | GVH - Graft Versus Host Reaction

United States
Children's Hospital of Philadelphia

Available

Expanded Access Protocol Using Alpha/Beta T and CD19+ Depleted PBSC

Leukemia | Immunodeficiencies | Bone Marrow Failure Syndrome

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Recruiting

Ex Vivo T-Cell Depletion of Mobilized Peripheral Blood Stem Cells Via CD34-Selection (EXCESS)

Stem Cell Transplant | Allogeneic

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome

Myelodysplastic Syndrome (MDS) | Severe Aplastic Anemia | Hypo-Plastic MDS

United States
Children's Hospital of Philadelphia
University of California, San Francisco

Recruiting

Alpha/Beta T and CD19+ Depleted Peripheral Stem Cells for Patients With Primary Immunodeficiencies

Immunodeficiencies | Immune Dysregulation Syndromes

United States
Masonic Cancer Center, University of Minnesota
Miltenyi Biomedicine GmbH

Withdrawn

CD3/CD19 Depleted or CD3 Depleted/CD56 Selected Haploid Donor Natural Killer Cell Treatment in Older AML in First Complete Remission

Acute Myelogenous Leukemia

United States
University of Wisconsin, Madison
University of Wisconsin Carbone Cancer Center (UWCCC)

Not yet recruiting

Alpha/Beta T-cell Depleted Blood-forming Stem Cell Transplant From Related or Unrelated Donors for Blood Diseases in Children and Young Adults

Blood Disease
St. Jude Children's Research Hospital

Active, not recruiting

TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies

Hodgkin Lymphoma | Myelodysplastic Syndromes (MDS) | Acute Myeloid Leukemia (AML) | Acute Lymphoblastic Leukemia (ALL) | Chronic Myeloid Leukemia (CML) | NK-Cell Leukemia | Non Hodgkin Lymphoma (NHL) | Juvenile Myelomonocytic Leukemia (JMML)

United States
Washington University School of Medicine

Recruiting

Haploidentical Hematopoietic Stem Cell Transplantation With Ex Vivo TCR Alpha/Beta and CD19 Depletion in Pediatric Hematologic Malignancies

Pediatric Hematologic Malignancies

United States
University of Regensburg

Recruiting

A Trial to Assess Haploidentical T-depleted Stem Cell Transplantation in Patients With SCD

Sickle Cell Disease | Sickle Cell Anemia | Sickle Cell Disorders | HbS Disease | Hemoglobin S Disease | Sickling Disorder Due to Hemoglobin S

Germany, Austria
Michael Pulsipher, MD
Children's Hospital of Philadelphia; Medical College of Wisconsin; University... and other collaborators

Enrolling by invitation

KIR Favorable Mismatched Haplo Transplant and KIR Polymorphism in ALL/AML/MDS Allo-HCT Children

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Acute Lymphoblastic Leukemia

United States
Michael Pulsipher, MD

Recruiting

Conditioning SCID Infants Diagnosed Early (CSIDE)

SCID

United States, Canada
University Hospital Tuebingen

Completed

Haploidentical Transplantation With CD3/CD19 Depleted Grafts in Patients With Hematologic Malignancies

Hematologic Malignancies

Germany
Memorial Sloan Kettering Cancer Center

Terminated

TCR Alpha Beta T-cell and CD19 B-cell Depleted Peripheral Blood Stem Cell Transplantation Using the CliniMACS System for Patients With Non-Malignant Hematologic Disorders From Matched or Mismatched, Related or Unrelated Donors

Non-Malignant Hematologic Disorders

United States
Weill Medical College of Cornell University

Terminated

Randomized HaploCord Blood Transplantation vs. Double Umbilical Cord Blood Transplantation for Hematologic Malignancies

Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | Myelodysplastic Syndrome | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia

United States
University of California, San Francisco

Recruiting

Autologous Gene Therapy for Artemis-Deficient SCID

Severe Combined Immunodeficiency

United States
St. Jude Children's Research Hospital

Recruiting

Study of CD19-directed Allogeneic Memory T-cell Therapy for Relapsed/Refractory CD19+ Leukemia

Pediatric ALL | Acute Lymphoblastic Leukemia, in Relapse | Acute Lymphoblastic Leukemia, Refractory

United States
St. Jude Children's Research Hospital

Active, not recruiting

Evaluation of CD19-Specific CAR Engineered Autologous T-Cells for Treatment of Relapsed/Refractory CD19+ Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia, in Relapse | Acute Lymphoblastic Leukemia, Refractory

United States
Washington University School of Medicine
The Leukemia and Lymphoma Society; Rising Tide Foundation; St. Louis Children...

Recruiting

Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AML (ABCD-NK)

Acute Myeloid Leukemia | Aml | AML, Childhood | Acute Myeloid Leukemia, Pediatric

United States
Masonic Cancer Center, University of Minnesota

Completed

NK Cell Based Non-Myeloablative Transplantation in Acute Myeloid Diseases

Acute Myeloid Leukemia | Myelodysplastic Syndrome

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Methods to Enhance the Safety and Effectiveness of Stem Cell Transplants

Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia

United States
Everett Meyer
Doris Duke Charitable Foundation

Terminated

Haploidentical Allogeneic Transplant With Post-transplant Infusion of Regulatory T-cells

Chronic Lymphocytic Leukemia (CLL) | Acute Lymphoblastic Leukemia (ALL) | Myelodysplastic Syndrome (MDS) | Acute Myelogenous Leukemia (AML) | Leukemia, Acute | Chronic Myelogenous Leukemia (CML) | Non-Hodgkin Lymphoma (NHL)

United States
Diane George

Recruiting

CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant

Acute Lymphoblastic Leukemia (ALL) | Myelodysplastic Syndrome (MDS) | Acute Myelogenous Leukemia (AML) | Chronic Myeloid Leukemia (CML) | Juvenile Myelomonocytic Leukemia (JMML) | Lymphoma (Hodgkin's and Non-Hodgkin's)

United States
Stanford University
Orca Biosystems, Inc.

Recruiting

Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft

Myelodysplastic Syndromes | Myeloproliferative Disorders | Acute Leukemia | Chronic Myelogenous Leukemia | Allogeneic Hematopoietic Cell Transplantation (HCT) | Advanced Hematologic Malignancies

United States
Weill Medical College of Cornell University

Active, not recruiting

Targeting the IPA and Matching for the Non-Inherited Maternal Antigen for Haplo-Cord Transplantation

Hematologic Malignancies

United States

Search clinical trials for: CliniMACS TCR α/β Reagent Kit and CliniMACS CD19

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