Search clinical trials for: Comparator: metformin

Total 4146 results

University of Manitoba

Completed

Ketamine Infusion for Pediatric Patients With Obstructive Sleep Apnea Syndrome (OSAS) After Tonsillectomy (KOSATA)

Obstructive Sleep Apnea Syndrome

Canada
Merck Sharp & Dohme LLC

Completed

Phase I Imaging Study Evaluating Gem/Cis or Gem/Carbo for Participants With Non-Small Cell Lung Cancer (MK-0000-083 AM3)

Carcinoma | Non-small Cell Lung Cancer
ViiV Healthcare

Terminated

A Dose Ranging Study Of GW640385 Boosted With Ritonavir (Rtv) In Comparison To A RTV-Boosted Protease Inhibitor (PI) In HIV-1 Infected PI-Experienced Adults

HIV-1 Infection | Infection, Human Immunodeficiency Virus I

United States, France, Germany, Canada, Italy, Australia, Belgium, Portugal, Puerto Rico, Romania, United Kingdom
Merck Sharp & Dohme LLC

Completed

Sitagliptin Added-on to Insulin Study (0431-051)

Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC

Completed

Treatment With MK0966 for the Prevention of Prostate Cancer (0966-201)

Prostate Cancer
Newcastle University
University College, London; University of Leeds; British Broadcasting Corporation and other collaborators

Completed

Turmeric Anti-Inflammatory and Cell-Damage Trial (TACT)

Healthy Adults

United Kingdom
University of Colorado, Denver
National Alliance for Research on Schizophrenia and Depression

Terminated

The Effects of Cannabis Use in People With Schizophrenia on Clinical, Neuropsychological and Physiological Phenotypes

Schizophrenia

United States
Cerimon Pharmaceuticals
PPD

Terminated

Diclofenac Patch for Treatment of Mild to Moderate Ankle Sprain

Ankle Sprain

United States
Henan Cancer Hospital

Not yet recruiting

Combination Followed by Maintenance Chemotherapy Versus CDK4/6 Inhibitor Combined With Endocrine Therapy for HR Low/HER2-negative Advanced Breast Cancer: a Prospective, Randomized, Open-label Phase Ⅱ Clinical Trial

Advanced Breast Cancer | Treatment | HR Low/HER2 Negative
Organon and Co

Completed

A Study of an Intravenous Drug in Pediatric Patients With Acute Asthma (0476-301)

Asthma
Corestemchemon, Inc.

Active, not recruiting

Evaluation the Efficacy and Safety of Mutiple Lenzumestrocel (Neuronata-R® Inj.) Treatment in Patients With ALS (ALSummit)

Amyotrophic Lateral Sclerosis

Korea, Republic of
Organon and Co

Completed

A Study of an Investigational Study Drug for Benign Prostatic Hyperplasia (0906-140)

Benign Prostatic Hyperplasia
Organon and Co

Completed

A Study of MK0663 and an Approved Drug in the Treatment of Osteoarthritis (0663-077)(COMPLETED)

Osteoarthritis
NYU Langone Health

Completed

Study on the Use of Low Dose Ketamine After Gastric Bypass and Gastrectomy

Pain | Postoperative Depression

United States
Juul Labs, Inc.

Completed

Characterize the Nicotine Uptake and Subjective Effects With Use of JUUL Electronic Nicotine Delivery Systems

Tobacco Smoking | Electronic Cigarette Use

United States
Bayer

Completed

Curing Atopic Dermatits in Children With a Commerical Medical Device and Maintaining Healthy Skin by Using a New Cosmetic Product

Dermatitis, Atopic

Germany
University of Dundee

Completed

Response To Oral Agents in Diabetes (ROAD)- Pilot Study (ROAD)

Diabetes Mellitus, Type 2

United Kingdom
National Institute of Nursing Research (NINR)

Completed

Genetic Basis For Variation In NSAID Analgesia In A Clinical Model Of Acute Pain

Pain

United States
Merck Sharp & Dohme LLC

Completed

An Observational Study of Type II Diabetics Treated With Dual Therapy With or Without Sitagliptin (Januvia®/Xelevia®, MK-0431-201)

Type 2 Diabetes Mellitus
AstraZeneca
Bristol-Myers Squibb

Completed

Evaluation of the Effect of Dapagliflozin in Combination With Metformin on Body Weight in Subjects With Type 2 Diabetes

Type 2 Diabetes Mellitus

Sweden, Bulgaria, Czech Republic, Hungary, Poland
Incannex Healthcare Ltd

Recruiting

RePOSA-Revealing the Efficacy of IHL-42X Use in Patients With OSA (REPOSA)

Obstructive Sleep Apnea

United States
Novartis Pharmaceuticals

Completed

A 26-week Treatment Randomized, Double-blind, Double Dummy Study to Assess the Efficacy and Safety of QVA149

Chronic Obstructive Pulmonary Disease

China, Argentina, Taiwan, Chile
Eurofarma Laboratorios S.A.

Withdrawn

Fixed-dose Combination of Etoricoxib + Cyclobenzaprine for Pain Relief After Third Molar Extraction in Brazil (BENCOX)

Third Molar Extraction

Brazil
Incyte Corporation

Recruiting

A Study to Assess the Effect of Povorcitinib on Digoxin, Rosuvastatin, and Metformin Pharmacokinetics When Administered Orally to Healthy Adult Participants

Healthy Participants

United States
AbbVie

Active, not recruiting

A Study Evaluating the Safety, Pharmacokinetics (PK), and Preliminary Efficacy of ABBV-399 in Participants With Advanced Solid Tumors

Advanced Solid Tumors Cancer

United States, Belgium, France, Italy, Japan, Korea, Republic of, Netherlands, Taiwan, Finland
Sidney Kimmel Cancer Center at Thomas Jefferson...

Completed

Durvalumab With or Without Metformin in Treating Participants With Head and Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma | Oropharyngeal Squamous Cell Carcinoma | Oral Cavity Squamous Cell Carcinoma

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Treatment Of Fever In The Emergency Department

Fever

Italy
Novartis Pharmaceuticals

Completed

Vildagliptin Compared to Glimepiride in Combination With Metformin in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

United States, Germany
Celgene
Impact Biomedicines, Inc., a wholly owned subsidiary of Celgene Corporation

Completed

Influence of Fedratinib on the Pharmacokinetics of the Transporter Probe Substrates Digoxin, Rosuvastatin, and Metformin

Healthy Volunteers

United States
Merck Sharp & Dohme LLC
Pfizer

Completed

A Study to Evaluate the Efficacy and Safety of Ertugliflozin in Asian Participants With Type 2 Diabetes and Inadequate Glycemic Control on Metformin Monotherapy (MK-8835-012)

Type 2 Diabetes Mellitus
Clinique Ovo

Withdrawn

Clomifene Citrate Versus Metformin in First-line Treatment of Infertility in Patients With Polycystic Ovary Syndrome and a Resistance to Insulin

Polycystic Ovary Syndrome | Insulin Resistance

Canada
Instituto Nacional de Ciencias Medicas y Nutricion...

Completed

Effects of Siliphos-Selenium-Methionine-Alpha Lipoic Acid in Patients With Fatty Liver and Non-alcoholic Steatohepatitis

Liver Disease

Mexico
Zekai Tahir Burak Women's Health Research and Education...

Completed

Oral Paracetamol Versus Oral Ibuprofen in Management of Patent Ductus Arteriosus in Preterm Infants: A Randomised Controlled Trial

Patent Ductus Arteriosus

Turkey
Sanofi

Completed

Insulin Glargine Combination Therapies in Type II Diabetics (LAPTOP)

Diabetes Mellitus, Type 2

France, Germany, Netherlands, Spain, Sweden, Switzerland, United Kingdom, Finland, Italy, Austria
Institute of Liver and Biliary Sciences, India

Not yet recruiting

To Compare the Safety and Efficacy of Dapagliflozin Plus Metformin Versus Sitagliptin Plus Metformin for Treatment of Diabetes in Patients With Compensated and Stable Decompensated Cirrhosis

Decompensated Cirrhosis | Compensated Cirrhosis

India
St. Joseph's Hospital and Medical Center, Phoenix

Terminated

Safety and Efficacy of Pre-incisional Intravenous Ibuprofen to Reduce Postoperative Pain and Opioid Dependence After Posterior Cervical or Lumbar Instrumented Spine Surgery

Cervical Spondylosis | Lumbar Spondylosis

United States
Yuzuncu Yıl University

Active, not recruiting

Evaluation the Effect of Using Preoperative Ibuprofen Versus Low Level Laser Therapy on Inferior Alveolar Nerve Block

Postoperative Pain

Turkey
Sanofi

Completed

Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination Versus Insulin Glargine in Patients With Type 2 Diabetes (LixiLan-India)

Type 2 Diabetes Mellitus

India
Takeda

Terminated

Comparison of Fasiglifam (TAK-875) With Sitagliptin When Used in Combination With Metformin in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

United States, Ukraine, Poland, Malaysia, Canada, Peru, Philippines, Hungary, Russian Federation, South Africa, Argentina, Croatia, Thailand
Biogen

Completed

Sorafenib With BIIB022 in Hepatocellular Carcinoma (HCC)

Hepatocellular Carcinoma

United States, Singapore, Taiwan, United Kingdom
Sanofi

Completed

Evaluation of Insulin Glargine in Combination With Sitagliptin in Type 2 Diabetes Patients: EASIE Extension Trial

Diabetes Mellitus, Type 2

United States, Brazil, Netherlands, Portugal, Spain, India, Austria, Egypt, Greece, Israel, Mexico, United Kingdom, Korea, Republic of, Hong Kong, Colombia, Lebanon
Sanofi

Completed

Evaluation of Insulin Glargine Versus Sitagliptin in Insulin-naive Patients (EASIE)

Diabetes Mellitus, Type 2

United States, Brazil, Netherlands, Portugal, Spain, Turkey, India, Austria, Egypt, Greece, Israel, Mexico, United Kingdom, Korea, Republic of, Hong Kong, Colombia, Lebanon
University Magna Graecia

Completed

Treatment of Anovulatory Infertility in PCOS Patients

Polycystic Ovary Syndrome | Infertility | Anovulation

Italy
59th Medical Wing

Completed

The Effect of Metformin Added to Clomiphene Citrate on Pregnancy Rates in Hyperandrogenic, Chronic Oligoovulatory or Anovulatory Women

Polycystic Ovary Syndrome | Hyperandrogenism | Infertility | Anovulation | Oligoovulation

United States
Merck Sharp & Dohme LLC
Pfizer

Completed

Ertugliflozin and Sitagliptin Co-administration Factorial Study (VERTIS FACTORAL, MK-8835-005)

Type 2 Diabetes Mellitus
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

DIrect Oral Anticoagulation and mechaNical Aortic Valve (DIAMOND)

Aortic Valve Disease

France
Daiichi Sankyo, Inc.

Completed

Edoxaban for Prevention of Blood Vessels Being Blocked by Clots (Thrombotic Events) in Children at Risk Because of Cardiac Disease

Cardiac Disease

United States, Spain, Canada, Lebanon, Turkey, Austria, Croatia, Egypt, France, Hungary, India, Israel, Ukraine, United Kingdom
Organon and Co

Completed

A Study of MK0663 and an Approved Drug in the Treatment of Osteoarthritis (0663-076)(COMPLETED)

Osteoarthritis
Aswan University Hospital

Completed

Bolus Administration of Intravenous Lidocaine at the Time of Abdominal Hysterectomy

Abdominal Hysterectomy

Egypt
University of British Columbia

Completed

Prophylactic Ondansetron in Post-op Cardiac Surgery Patients to Prevent Post-operative Nausea and Vomiting

Postoperative Nausea and Vomiting

Canada

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