Search clinical trials for: Cytochrome P-450 CYP1A2 Inhibitors

Total 7146 results

Alexion
Achillion, a wholly owned subsidiary of Alexion

Completed

Elvucitabine/Efavirenz/Tenofovir Versus Lamivudine/Efavirenz/Tenofovir in Human Immunodeficiency Virus (HIV)-1 Infected, Treatment-naive Participants

HIV Infections

United States, Puerto Rico
Peking Union Medical College Hospital
Gilead Sciences

Active, not recruiting

Biktarvy in Treatment-Naïve Late Presenters With HIV-1 Infection

HIV-1-infection

China
National Institute of Allergy and Infectious Diseases...

Withdrawn

Treatment of Hepatitis B Virus (HBV) Before Beginning Anti-HIV Drugs in Patients With Both HBV and HIV

HIV Infections | Hepatitis B
Hospital Universitari Vall d'Hebron Research Institute
Gilead Sciences

Completed

Evolution of Plasma Lipid Profile in Patients With HIV1 Who Change Atripla to Eviplera Compared to Continue With Atripla

HIV-1

Spain
Gilead Sciences

Completed

ROCKET I - Randomized Open Label Switch for Cholesterol Elevation on Kivexa Evaluation Trial (ROCKET I)

HIV Infections

United Kingdom
Gilead Sciences
Bristol-Myers Squibb

Completed

Single Tablet Regimen (STR) Simplification Study for HIV-1 Infected Patients

HIV Infections

United States, Puerto Rico
International Antiviral Therapy Evaluation Center
Boehringer Ingelheim

Completed

2NN & CHARM Long-Term Follow-up Study

HIV Infections

Australia
Radboud University Medical Center

Recruiting

Pragmatic Optimized Rifampicin Trial (PORT)

Tuberculosis, Pulmonary

Netherlands
Children's Hospital of Philadelphia
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Rifampin in CYP24A1-related Hypercalcemia and Hypercalciuria (RICHH)

Genetic Disease | Hypercalciuria | Idiopathic Infantile Hypercalcemia - Mild Form | Idiopathic Infantile Hypercalcaemia - Severe Form | Hypercalcemia, Idiopathic, of Infancy | Hypercalciuric Hypercalcemia

United States
Makerere University

Completed

Safety and Efficacy of High Dose Rifampicin in Tuberculosis (TB)-HIV Co-infected Patients on Efavirenz- or Dolutegravir-based Antiretroviral Therapy (SAEFRIF)

Tuberculosis

Uganda
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Investigate the Effect of Rifampicin on the Uptake and Breakdown of ACT-246475 in Healthy Subjects

Healthy Subject

Netherlands
Yale University
Gilead Sciences

Withdrawn

A Study of the Pharmacokinetic and Pharmacodynamic Interactions Between Bictegravir, Tenofovir Alafenamide and Rifapentine in Healthy Adult Subjects

Tuberculosis | Hiv

United States
R-Pharm

Completed

Effect of Rifampin on the Pharmacokinetics of Ixabepilone in Patients With Advanced Cancer

Neoplasms | Advanced Solid Tumors

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Drug-drug Interaction Trial to Evaluate the Pharmacokinetics Effect of Rifampicin on Famitinib

Healthy Adult Subjects

China
Global Alliance for TB Drug Development

Completed

PK Interaction Between Rifapentine or Rifampicin and a Single Dose of TMC207 in Healthy Subjects (TMC207-CL002)

Tuberculosis

United States
Pfizer

Completed

A Study To Evaluate The Effect Of Rifampin On Pharmacokinetics Of PF-06463922 In Healthy Volunteers

Healthy

United States
Eisai Limited

Completed

To Assess the Effect of Rifampicin on the Pharmacokinetics of Eribulin Mesylate in Participants With Advanced Solid Tumors

Tumor

Netherlands
Radboud University Medical Center
Sanofi; European and Developing Countries Clinical Trials Partnership (EDCTP); National Institute for Public Health and the Environment (RIVM) and other collaborators

Completed

Pharmacokinetics and Pharmacodynamics of High Versus Standard Dose Rifampicin in Patients With Pulmonary Tuberculosis (High RIF)

Tuberculosis

Tanzania
University of Campania "Luigi Vanvitelli"
Federico II University

Completed

Colistin and Rifampicin for MDR-Acinetobacter (CoRAb)

Pneumonia, Ventilator-Associated | Hospital Acquired Pneumonia | Infection Due to Resistant Bacteria | Infection of Bloodstream | Infectious Disease of Abdomen
Ranbaxy Laboratories Limited

Completed

Bioequivalence Study of Clarithromycin 250mg Tablets Under Fasting Conditions

Healthy

India
Oregon Health and Science University
University Health Network, Toronto; New York University; NTM Info & Research,...

Recruiting

Hypertonic Saline for MAC

Nontuberculous Mycobacterial Lung Disease | Nontuberculous Mycobacterium Infection

United States, Canada
University of Colorado, Denver
Merck Sharp & Dohme LLC

Completed

Rifampin and the Contraceptive Implant

Tuberculosis | Contraception

United States
Bristol-Myers Squibb

Withdrawn

Study to Evaluate the Effect of Rifampin on the Drug Levels in Blood and Safety of BMS-986235 in Healthy Participants

Healthy Participants

United States
Radboud University Medical Center
European and Developing Countries Clinical Trials Partnership (EDCTP); Department... and other collaborators

Completed

Safety, Tolerability, Extended Early Bactericidal Activity and PK of Higher Doses Rifampicin in Adults With Pulmonary TB (HR1)

Pulmonary Tuberculosis (TB)

South Africa
University of Utah
Cubist Pharmaceuticals LLC

Completed

Influence of Rifampin Co-Administration on the Pharmacokinetic Profile of Daptomycin

Pharmacokinetics | Drug Interactions

United States
AbbVie
Genentech, Inc.

Withdrawn

A Study to Assess the Effect of Rifampin on the Metabolism of ABT-199

Non-Hodgkin's Lymphoma

United States
Seoul National University Hospital

Completed

A Pilot Study for Pharmacokinetic Parameter of Colchicine in Patient Taking Rifampin

Tuberculosis | Chronic Kidney Disease
Boehringer Ingelheim

Terminated

Pharmacokinetic Interaction Between Nevirapine and Saquinavir-sgc in HIV-1 Infected Patients

HIV Infections
The Hospital for Sick Children
Children's Hospital of Philadelphia; Canadian Institutes of Health Research... and other collaborators

Recruiting

The Antibiotic Rifampin to Reduce High Levels of Blood and Urine Calcium in IIH

Idiopathic Infantile Hypercalcemia - Mild Form

Canada
Ann & Robert H Lurie Children's Hospital of Chicago

Recruiting

A Novel Probiotic-antibiotic Combination to Prevent Recurrent Urinary Tract Infections

Recurrent Uti

United States
Radboud University Medical Center
University College, London; Academisch Medisch Centrum - Universiteit van Amsterdam... and other collaborators

Terminated

S. Aureus Decolonization in HPN Patients. (CARRIER)

Staphylococcus Aureus | Motility Disorder

Denmark, Netherlands
National Institute of Allergy and Infectious Diseases...

Completed

A Study of Abacavir Plus Indinavir Sulfate Plus Efavirenz in HIV-Infected Patients

HIV Infections

United States, Puerto Rico
Merck Sharp & Dohme LLC

Completed

Indinavir Plus Efavirenz Plus Adefovir Dipivoxil in HIV-Infected Patients Who Have Not Had Success With Nelfinavir

HIV Infections

United States
Boehringer Ingelheim

Completed

Drug Interaction Study With Rifampicin and Afatinib

Healthy

Germany
Pfizer

Completed

Estimate The Effect Of Repeat-Dose Rifampin On The Pharmacokinetics Of CP-690,550 In Healthy Volunteers

Healthy

United States
Beta Pharma, Inc.

Completed

A Phase I Study to Assess the Effect of Itraconazole and Rifampicin on Pharmacokinetics Profile of BPI-7711

NSCLC

China
F2G Biotech GmbH
Hammersmith Medicines Research

Completed

Drug-drug Interaction (DDI) Study to Assess Effect of Itraconazole and Rifampicin Upon Olorofim

Healthy

United Kingdom
Millennium Pharmaceuticals, Inc.

Completed

Safety, Tolerability and Pharmacokinetic (PK) of Concomitant Esomeprazole and Rifampin, and QT Study on Single and Multiple-doses of Alisertib

Lymphoma | Solid Tumors

United States
Region Skane

Completed

MESS-study MRSA Eradication Study Skåne (MESS)

Throatcarriers of MRSA

Sweden
Hoffmann-La Roche

Completed

A Pharmacokinetics (PK) Study to Investigate the Effect of Rifampin on PK of Vemurafenib (Zelboraf)

Malignant Melanoma, Neoplasms

United States, South Africa, Croatia, Brazil, Egypt
Tibotec Pharmaceuticals, Ireland

Completed

TMC435350-TiDP16-C105: Phase I, 3-way Crossover, Drug-drug Interaction Between TMC435350 and Rifampin After Multiple Dosing.

Hepatitis C | Tuberculosis | Pharmacokinetics | HCV | Rifampin
Pfizer

Completed

Estimation Of Effect Of Rifampin On Pharmacokinetics Of Crizotinib In Healthy Volunteers

Healthy

United States
GlaxoSmithKline

Completed

A Cross-over Study to Evaluate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics (PK) of GSK525762 in Healthy Female Subjects of Non Child Bearing Potential

Neoplasms | Drug Interactions

United States
National Center for Research Resources (NCRR)
Centers for Disease Control and Prevention

Unknown

Intensive Pharmacokinetics of the Nelfinavir-Rifabutin Interaction in Patients With HIV-Related Tuberculosis Treated With a Rifabutin-Based Regimen

HIV Infections | Tuberculosis

United States
Emergency NGO Onlus

Withdrawn

Clinical Study to Assess Efficacy and Safety of Amiodarone in Treating Patients With Ebola. Virus Disease (EVD) in Sierra Leone. EASE (EMERGENCY Amiodarone Study Against Ebola) (EASE)

Ebola Virus Disease
Kuopio University Hospital
Tampere University Hospital; Vaasa Central Hospital, Vaasa, Finland

Completed

Intravenous Metoprolol Versus Intravenous Amiodarone in the Prevention of Atrial Fibrillation After Cardiac Surgery

Atrial Fibrillation | Cardiac Surgery

Finland
ProRhythm, Inc.

Suspended

High Intensity Focused Ultrasound (HIFU) Ablation System Study

Atrial Fibrillation

United States, Czech Republic
The University of Hong Kong

Suspended

Immunomodulatory Effect of Macrolides in Naturally Occurring Influenza Virus Infections in the Community

Influenza, Human

Hong Kong
University of Virginia
Rutgers University; Haydom Lutheran Hospital

Not yet recruiting

Precision Rifampin Trial for Personalized Dosing (P-RIF)

Tuberculosis
Hospital Universitari Vall d'Hebron Research Institute
Radboud University Medical Center; University Medical Center Groningen; Centro... and other collaborators

Not yet recruiting

Rifampicin at High Dose for Difficult-to-Treat Tuberculosis (RIAlta)

Tuberculosis

Spain, Netherlands, Paraguay, Portugal

Search clinical trials for: Cytochrome P-450 CYP1A2 Inhibitors

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