Search clinical trials for: Cytochrome P-450 CYP3A Inducers

Total 5584 results

Reata, a wholly owned subsidiary of Biogen
Celerion; Q2 Solutions; Altasciences Company Inc.

Completed

An Open-label DDI Study of Omaveloxolone in Healthy Subjects

Healthy Adult Subjects

United States
Case Western Reserve University
Massachusetts General Hospital; University Hospitals Cleveland Medical Center

Completed

Efavirenz for Patients With Alzheimer's Disease (EPAD)

Alzheimer Disease, Early Onset

United States
Daiichi Sankyo Co., Ltd.

Completed

A Study of the Effect of a Moderate CYP3A Inducer Efavirenz on Quizartinib Pharmacokinetics in Healthy Participants

Healthy Subjects | Pharmacokinetics | Drug-drug Interaction | Quizartinib

United States
Institut Bergonié

Completed

Efavirenz in Treating Patients With Metastatic Prostate Cancer (FAVE)

Prostate Cancer

France
Johns Hopkins University
American College of Obstetricians and Gynecologists; The Campbell Foundation

Terminated

Pharmacokinetics and Pharmacodynamics of the Etonogestrel Contraceptive Implant When Co-administered With Efavirenz

Drug Interaction

United States
Oswaldo Cruz Foundation
Ministry of Health, Brazil

Terminated

Randomized Clinical Trial to Assess the Efficacy and Safety of Concomitant Use of Rifampicin and Efavirenz 600 X 800mg (IPEC-EFV)

HIV Infections | Tuberculosis

Brazil
Mahidol University

Unknown

Influence of Cytochrome P2B6 on Efavirenz Dose in HIV-infected Thai Patients

HIV | Cytochrome P-450 CYP2B6 | Efavirenz

Thailand
University Hospital, Geneva
University Hospital, Basel, Switzerland; University of Lausanne Hospitals; University... and other collaborators

Completed

Patient Preference, Sleep Quality, and Anxiety/Depression: A Randomized Comparison of Etravirine and Efavirenz (SWITCH-EE)

Sleep Disorders

Switzerland
McGill University Health Centre/Research Institute...
Canadian Institutes of Health Research (CIHR)

Active, not recruiting

2R2: Higher Dose Rifampin for 2 Months vs Standard Dose Rifampin for Latent TB. (2R2)

Latent Tuberculosis

Canada, Indonesia, Vietnam
Sunshine Lake Pharma Co., Ltd.

Completed

Effects of Rifampicin and Probenecid On The Pharmacokinetic Profile Of Rongliflozin In Healthy Subjects

Type 2 Diabetes Mellitus

China
Tuberculosis Research Centre, India

Completed

Comparing Daily vs Intermittent Regimen of ATT in HIV With Pulmonary Tuberculosis

HIV Infection | Pulmonary TB

India
Harvard University Faculty of Medicine
National Institute of Allergy and Infectious Diseases (NIAID); Sanofi; University... and other collaborators

Completed

Trial of High-Dose Rifampin in Patients With TB (HIRIF)

Tuberculosis

United States, Peru, United Kingdom
Boehringer Ingelheim

Completed

Drug Interaction Study With Rifampicin and Afatinib

Healthy

Germany
University of California, San Francisco

Completed

Drug Interaction Study of Rifampin and Warfarin in Healthy Volunteers.

Healthy

United States
Pfizer

Completed

Estimate The Effect Of Repeat-Dose Rifampin On The Pharmacokinetics Of CP-690,550 In Healthy Volunteers

Healthy

United States
Shanghai Public Health Clinical Center

Not yet recruiting

Efficacy of 400 mg Efavirenz Versus Standard 600 mg Dose in HIV/TB Co-infected Patients

HIV Infections | Tuberculosis
University of Nebraska

Completed

EFV Pharmacokinetics & Pharmacogenomics in Older HIV-infected Patients (EFV)

HIV Infection

United States
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

A Trial of DDI Between SHR1459 and Efavirenz With Healthy Subjects

B-cell Tumors

China
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Drug-drug Interaction Study of SHR6390 on Healthy Chinese Volunteers

Advanced Solid Tumor

China
National Institute of Allergy and Infectious Diseases...

Completed

Safety, Tolerability, and Effect of TMC207 and Efavirenz in Healthy Volunteers

HIV | Tuberculosis

United States
The HIV Netherlands Australia Thailand Research...
Ministry of Education, Thailand

Completed

A Pharmacokinetic Study of Once Daily Efavirenz 400 mg Versus 600 mg in Thai HIV-1 Infected Subjects

HIV Infections

Thailand
Indiana University

Completed

Effects of CYP2B6 Genetic Polymorphisms on Efavirenz Pharmacokinetics

HIV

United States
Yuria-Pharm

Terminated

Efficacy and Safety of Intravenous Treatment of Tuberculosis

Tuberculosis, Pulmonary

Ukraine
Actelion

Completed

A Clinical Study to Investigate the Effect of Gemfibrozil or Rifampicin on Blood Concentrations of Selexipag in Healthy Subjects

Healthy Subjects

Germany
Shouyao Holdings (Beijing) Co. LTD

Not yet recruiting

A Study to Evaluate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics of SY-5007 in Healthy Subjects

Healthy Subjects

China
Basilea Pharmaceutica

Completed

A Drug-Drug Interaction Study of CYP3A4 Inhibition and Pan-CYP Induction on APX001

Fungal Infection

Netherlands
Celgene

Terminated

A Safety and Efficacy Study of CC-90011 in Participants With Relapsed and/or Refractory Solid Tumors and Non-Hodgkin's Lymphomas

Neoplasms | Lymphoma, Non-Hodgkin

France, Italy, Japan, Spain, United Kingdom
Dong-A ST Co., Ltd.

Completed

Evaluate the Effect of Clarithromycin/Rifampicin on the Pharmacokinetics of DA-8010 in Healthy Adults

Healthy

Korea, Republic of
Epizyme, Inc.

Completed

Study to Describe the Interaction Between Tazemetostat and Itraconazole and Between Tazemetostat and Rifampin in Participants With Advanced Cancer

Solid Tumor | Mesothelioma | Rhabdoid Tumor | Hematologic Malignancy | Advanced Malignancies | Synovial Sarcoma | Renal Medullary Carcinoma | Diffuse Large B-Cell Lymphoma (DLBCL) | Follicular Lymphoma (FL) | Non-Hodgkin Lymphoma (NHL) | All Malignancies | Epithelioid Sarcoma (ES)

Spain, United States
Beijing InnoCare Pharma Tech Co., Ltd.

Completed

DDI Study of Orelabrutinib

Healthy Person

China
AnHeart Therapeutics Inc.

Completed

A Study of AB-106 in Chinese Healthy Adult Men Evaluated the Effects of Itraconazole and Rifampicin on AB-106 PK

Solid Tumor

China
Eli Lilly and Company
Loxo Oncology, Inc.

Completed

A Study of Effects of Itraconazole and Rifampin on Selpercatinib (LY3527723) in Healthy Participants

Healthy

United States
Bayer
Orion Corporation, Orion Pharma

Completed

Drug-drug Interaction (DDI) Study to Assess ODM-201 as a Victim of CYP3A4 Inhibition or Induction

Biological Availability

Germany
Vanda Pharmaceuticals

Completed

Pharmacokinetics of Tasimelteon Alone and in Combination With a CYP3A4 Inhibitor, Ketoconazole, or a CYP3A4 Inducer, Rifampin.

Healthy

United States
Boryung Pharmaceutical Co., Ltd

Completed

A Study to Evaluate the Effect of Ketoconazole and Rifampicin on the Pharmacokinetics of Fimasartan in Healthy Male Volunteers

Essential Hypertension
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

Drug-drug Interaction Study of HRS-1780 Tablets in Healthy Subjects

Chronic Kidney Disease(CKD)

China
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

A Study to Evaluate Drug-Drug Interaction of TQB3909 Tablets

Advanced Malignant Neoplasm

China
Shanghai Henlius Biotech

Completed

Study on Food Influence and Drug-drug Interaction of HLX208 Tablets in Chinese Healthy Subjects

NSCLC

China
Sunshine Lake Pharma Co., Ltd.

Active, not recruiting

A Study to Evaluate Drug-Drug Interaction of Larotinib With Itraconazole and Rifampin in Healthy Adult Participants (Z650)

Healthy Volunteers

China
Hutchison Medipharma Limited
Covance

Completed

Fruquintinib CYP3A Inhibitor and Inducer Study

Drug Drug Interaction

United States
Millennium Pharmaceuticals, Inc.

Completed

A Study to Evaluate Drug-Drug Interaction of TAK-788 With Itraconazole and Rifampin in Healthy Adult Participants

Healthy Volunteers

United States
Agios Pharmaceuticals, Inc.

Completed

Study to Evaluate the Effect of Multiple Doses of Itraconazole and Rifampin on the Single-Dose Pharmacokinetics of Mitapivat Sulfate (AG-348) in Healthy Adult Participants

Healthy Volunteers

United States
Universitaire Ziekenhuizen KU Leuven

Completed

Phenotypic Drug Probes as Predictors of Drug-drug Interactions With Tacrolimus

Kidney Transplantation | Drug Interactions

Belgium
Bristol-Myers Squibb

Completed

A Study to Evaluate the Effect of 2 Drugs on the Pharmacokinetics of BMS-986205 in Healthy Subjects

Malignancies Multiple

United States
Boehringer Ingelheim

Completed

Drug-drug Interaction (DDI) With a P-gp Inhibitor, Organic Anion Transporting Polypeptide OATP-inhibitor, Food Effect

Healthy

Germany
Genentech, Inc.

Completed

A Drug Interaction Study of GDC-0032 Co-administered With Rifampin or Itraconazole in Healthy Volunteers

Healthy Volunteer

United States
University of Cape Town

Completed

The Bioavailability of Rifampicin in (FDCs) Widely Used in South Africa to Treat Drug-susceptible (TB) (BIO3FDC)

Tuberculosis

South Africa
Assiut University

Not yet recruiting

Efficacy Of Doxycycline & Versus Rifampin In Treatment Of Rhinoscleroma

Rhinoscleroma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

A Study to Evaluate Drug-Drug Interaction of TQ05105 Tablets

Myelofibrosis

China
Boehringer Ingelheim

Recruiting

A Study in People With Advanced Cancer to Test Whether the Amount of BI 907828 in the Blood is Influenced by Taking an OATP Inhibitor or a CYP3 Inhibitor

Solid Tumors

Spain, Belgium

Search clinical trials for: Cytochrome P-450 CYP3A Inducers

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