Search clinical trials for: Cytochrome P-450 Enzyme Inhibitors

Total 47789 results

Washington University School of Medicine

Completed

Efavirenz and Ritonavir on Human Brain P-Glycoprotein

Drug Effects

United States
University of California, San Francisco
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Protease Inhibitors to Reduce Malaria Morbidity in HIV-Infected Pregnant Women (PROMOTE-PIs)

HIV Infections | Malaria

Uganda
Columbia University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Treatment Options for Protease Inhibitor-exposed Children (NEVEREST-III)

HIV Infections | HIV/AIDS

South Africa
The HIV Netherlands Australia Thailand Research...
Chulalongkorn University; Khon Kaen University

Completed

PK TDF in Thai HIV-infected Children

HIV

Thailand
French National Agency for Research on AIDS and...
Gilead Sciences; Abbott

Completed

Evaluation of a Lopinavir/Ritonavir Monotherapy vs a Triple Therapy as Maintenance Regimens in HIV-1 Infected Patients (ANRS 140 DREAM)

HIV Infections

France
Bristol-Myers Squibb

Completed

Dose Finding Confirmation of Atazanavir With Ritonavir and Efavirenz (ATV/RTV + EFV) in Healthy Subjects

HIV Infections | Protease Inhibitor

United States
National Institute of Diabetes and Digestive and...

Unknown

HIV Antiretroviral Drugs and Metabolism

HIV Infections

United States
Takeda

Completed

A Study of Soticlestat and Rifampin in Healthy Adults

Healthy Volunteers

United Kingdom
SecuraBio

Completed

Phase 1 Study in Healthy Subjects to Evaluate the Effect of Rifampin on the Pharmacokinetics of IPI-145 (DDI)

Healthy

United States
Johns Hopkins University

Withdrawn

Epidemiology and Treatment of Small-colony Variant Staphylococcus Aureus in Cystic Fibrosis

Cystic Fibrosis | MRSA

United States
Hoffmann-La Roche

Completed

A Study to Investigate the Effect of Rifampicin on the PK of Multiple Doses of Balovaptin In Healthy Volunteers

Healthy Volunteers

Netherlands
Eli Lilly and Company

Completed

A Study of LY2835219 in Healthy Participants

Healthy Volunteers

United States
Bristol-Myers Squibb

Completed

An Investigational Study to Evaluate the Effect of Rifampin on the Singe Dose of Experimental Medication BMS-986224 in Healthy Participants

Healthy Participants

United States
University of Oulu
Oulu University Hospital

Completed

The Effects of PXR Activation on Hepatic Fat Content

Non-alcoholic Fatty Liver Disease

Finland
National Institute of Allergy and Infectious Diseases...

Completed

TMC207 +/- Rifabutin/Rifampin

Tuberculosis

United States
Hoffmann-La Roche

Completed

A Study of the Effect of Multiple Doses of Rifampin on the Single Dose Pharmacokinetics of RO5424802

Healthy Volunteer

United States
Nivalis Therapeutics, Inc.
Davita Clinical Research

Completed

A Drug-Drug Interaction Study of N91115 +/- Rifampin in Healthy Adult Subjects

Drug Interaction Potentiation

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Effect of Rifampin on the Pharmacokinetics of PCI-32765 in Healthy Participants

Healthy Participants

United States
University of North Carolina, Chapel Hill
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Terminated

Safety and Pharmacokinetics of Single and Multiple Dose Rifampin in Infants

Infection

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study to Determine the Impact of Multiple Doses of Rifampin on Single-dose Pharmacokinetics of HCV-796

Healthy
ANRS, Emerging Infectious Diseases
Merck Sharp & Dohme LLC; Ministry of Health, Brazil

Completed

Raltegravir Versus Efavirenz in Naive HIV-1-infected Patients Receiving Rifampin for Active Tuberculosis (REFLATE TB2)

Tuberculosis | HIV-1 Infection

France, Vietnam, Brazil, Côte D'Ivoire, Mozambique
Bristol-Myers Squibb

Completed

Study to Determine the Effect of Efavirenz on the ECG QTcF Interval in Healthy Subjects

HIV/AIDS

United States
St Stephens Aids Trust

Completed

PK Switch Efavirenz to Maraviroc in Patients Initially Suppressed on an Efavirenz-containing Regimen (SSAT033)

HIV Infection

United Kingdom
University of California, San Francisco

Withdrawn

Interplay Between Organic Anion Transporting Polypeptide (OATP) Transporters Transporters and CYP2C9 in Glyburide Pharmacokinetics (PK)

Healthy
Beijing Anzhen Hospital

Recruiting

Nifekalant Versus Amiodarone in New-Onset Atrial Fibrillation After Cardiac Surgery

New Onset Atrial Fibrillation | Complications; Cardiac, Postoperative

China
University of Calgary

Recruiting

Oral Amiodarone for Acute Cardioversion of Atrial Fibrillation Study (AAA)

Atrial Fibrillation

Canada
Ottawa Hospital Research Institute

Recruiting

Prophylaxis for Patients at Risk to Eliminate Post-operative Atrial Fibrillation (PREP-AF)

Atrial Fibrillation

Canada
InCor Heart Institute
Ministry of Health, Brazil; Abbott Medical Devices

Recruiting

Amiodarone Against ICD Therapy in Chagas Cardiomyopathy for Primary Prevention of Death (CHAGASICS)

Chagas Cardiomyopathy | Non-sustained Ventricular Tachycardia | At Least 10 Points in Rassi Risk Score for Death

Brazil
University of Sao Paulo General Hospital

Unknown

Control Versus Liberal Cardiac Frequency in Patients in Sepse With Atrial Fibrillation of High Ventricular Response (FAARV)

Sepsis | Septic Shock | Atrial Fibrillation | Ventricular Fibrillation | Atrial Fibrillation Rapid

Brazil
Beth Israel Deaconess Medical Center

Terminated

Study of Amiodarone Given Before Lung Surgery to Prevent Atrial Fibrillation After Lung Resection

Atrial Fibrillation | Lung Cancer

United States
Sanofi

Completed

Efficacy & Safety of Dronedarone Versus Amiodarone for the Maintenance of Sinus Rhythm in Patients With Atrial Fibrillation (DIONYSOS)

Atrial Fibrillation

United States, France, Canada, Poland, Russian Federation, Germany, Netherlands, Sweden, Turkey, Estonia, Belgium, Czech Republic, Mexico, Tunisia, Argentina, Austria, Finland, Italy, Korea, Republic of, Chile, Morocco, China, Austr...
Brigham and Women's Hospital
University of Cape Town; APIN Public Health Initiatives

Recruiting

Dolutegravir Pharmacokinetics Among HIV/TB Coinfected Children Receiving Standard and High-dose Rifampicin

Tuberculosis Infection | Pediatric HIV Infection

Nigeria
Jiangsu HengRui Medicine Co., Ltd.

Completed

Effect of Rifampicin on the Pharmacokinetics of HRS-1167 in Healthy Subjects

Advanced Solid Tumor

China
Institute of Tropical Medicine, Belgium
Leiden University Medical Center; Damien Foundation; Instituto Fernandes Figueira and other collaborators

Completed

Post ExpOsure Prophylaxis for LEprosy in the Comoros and Madagascar (PEOPLE)

Leprosy

Comoros, Madagascar
Amgen

Completed

A Study to Evaluate the Drug-drug Interaction Effect of Rifampin on the Pharmacokinetics of AMG 510 in Healthy Participants

Healthy Participants

United States
Phathom Pharmaceuticals, Inc.

Withdrawn

Evaluation of Effect of Rifampin on the Pharmacokinetics of Vonoprazan in Healthy Participants

Healthy Participants

United States
Shanghai Public Health Clinical Center

Completed

The Drug Interaction Between Albuvirtide (ABT) and Rifampin（RIF） in Healthy Adult Subjects

Drug Interaction

China
Millennium Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Effect of Single-Dose Intravenous Rifampin as a Prototypic Inhibitor of Organic Anion Transporting Polypeptide (OATP) 1B1 and OATP1B3 on the Single-Dose Pharmacokinetics (PK) of Oral TAK-906 in Healthy Adult Participants

Healthy Volunteers

United States
Eli Lilly and Company

Completed

A Study of Baricitinib and Rifampicin in Healthy Participants

Healthy Volunteers

United Kingdom
National University Hospital, Singapore

Suspended

Whole Blood Bactericidal Activity (WBA) Against Mycobacterium Tuberculosis of Rifampicin in Healthy Volunteers

Tuberculosis

Singapore
Hoffmann-La Roche

Completed

A Study to Investigate the Effects of Rifampicin on the Pharmacokinetics of Aleglitazar in Healthy Volunteers

Healthy Volunteer

United Kingdom
Janssen Research & Development, LLC

Completed

A Drug Interaction Study in Healthy Participants to Assess the Effect of Rifampin on the Pharmacokinetics of JNJ-42847922

Healthy

United States
Bristol-Myers Squibb

Withdrawn

A Study of the Interaction of Rifampin and Vinflunine in Subjects With Advanced Cancer

Cancer

United States
University Medicine Greifswald

Completed

Impact of Two Genetic Variants of OATP1B3 or MRP2 or Rifampin on Systemic Disposition and Biological Efficacy of CCK-8

Gastrointestinal Hormones

Germany
Pfizer

Completed

Understanding The Effect Of A Strong CYP3A4 Inducer On Glasdegib Pharmacokinetics

Healthy Volunteers

United States
AstraZeneca

Completed

To Assess the Effect of Rifampicin on the Pharmacokinetics of Selumetinib in Healthy Male Volunteers

Solid Tumours

United States
Michael Hoelscher
Quintiles, Inc.; German Federal Ministry of Education and Research; Parexel; European... and other collaborators

Completed

Early Bactericidal Activity (EBA) of SQ109 in Adult Subjects With Pulmonary TB (SQ109EBA)

Tuberculosis, Pulmonary

South Africa
AstraZeneca

Completed

Effects of Administration of Fostamatinib on Blood Concentrations of Rifampicin in Healthy Subjects.

Rheumatoid Arthritis | Healthy Volunteers

United States
Bristol-Myers Squibb
PRA Health Sciences

Completed

Drug-Drug Interaction Study With Rifampin

Alzheimer Disease

India
Boehringer Ingelheim

Completed

Drug-drug Interaction Trial Between Rifampicin and BI 409306 in Healthy Volunteers

Healthy

Germany

Search clinical trials for: Cytochrome P-450 Enzyme Inhibitors

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