Search clinical trials for: DE-089 ophthalmic solution

Total 2061 results

Stefania La Grutta, MD

Completed

Effects of Hypertonic Saline Solution (NACL 3%+NAHCO3) on Nasal Inflammation in Children With AR. RinASol- Pilot Study (RinASol)

Allergic Rhinitis

Italy
Merck Sharp & Dohme LLC

Completed

A Safety and Tolerability Study of Denufosol in 2-4 Year Olds (REACH-1)

Cystic Fibrosis
Nicholas M Mohr

Completed

Saline vs. Lactated Ringers for Emergency Department IV Fluid Resuscitation

Emergencies | Fluid Loss | Symptom Complex, Triple

United States
University of Miami

Completed

The Effect of Lumify™ Eyedrops on Eyelid Position

Eyelid Droop

United States
Bausch & Lomb Incorporated

Completed

Indomethacin Eyedrops Compared With Ketorolac Eyedrops for Ocular Inflammation Following Cataract Surgery

Inflammation | Cataract

Germany
Allergan

Completed

Efficacy and Safety of COMBIGAN® in Korean Patients With Primary Open Angle Glaucoma (POAG) and Normal Tension Glaucoma (NTG)

Glaucoma, Open-Angle | Normal Tension Glaucoma

Korea, Republic of
Ophthalmic Consultants of Boston
Bausch & Lomb Incorporated

Unknown

Safety Study of Bromfenac Ophthalmic Solution in Subjects With Diffuse Diabetic Macular Edema (DME) Refractory to Laser

Diabetic Macular Edema

United States
Assistance Publique - Hôpitaux de Paris

Completed

Efficacy of 3% Hypertonic Saline in Acute Viral Bronchiolitis (GUERANDE)

Acute Viral Bronchiolitis

France
University of Alberta

Withdrawn

A Study to Systematically Assess the Efficacy and Safety of Intravenous Albumin Infusions in Severe POTS

Postural Orthostatic Tachycardia Syndrome
Spektrum Center of Clinical Ophthalmology
Wrocław University of Science and Technology

Active, not recruiting

Eye Surface Properties After Using Dexamethasone Drops With and Without Preservatives in Patients After Cataract Surgery (EyeSurface)

Healing Wound | Cataract | Surgical Injury

Poland
Alcon, a Novartis Company

Completed

LHA510 Proof-of-Concept Study as a Maintenance Therapy for Patients With Wet Age-Related Macular Degeneration

Exudative Age-Related Macular Degeneration

United States
Prof. Dr. Jörg Leuppi

Terminated

Inhaled Aviptadil for the Treatment of COVID-19 in Patients at High Risk for ARDS

Covid19 | Corona Virus Infection | ARDS | Aviptadil

Switzerland
Bioverativ, a Sanofi company
Assign Data Management and Biostatistics GmbH; Quest Diagnostics-Nichols Insitute and other collaborators

Completed

Safety, Tolerability and Activity of BIVV009 in Healthy Volunteers and Patients With Complement Mediated Disorders (BIVV009-01)

End-stage Renal Disease (ESRD) | Cold Agglutinin Disease (CAD) | Bullous Pemphigoid (BP) | Warm Autoimmune Hemolytic Anemia (WAIHA)

Austria
Novo Nordisk A/S

Completed

Investigation of Pain During Subcutaneous Injections With Different Injection Speed and Volume Combinations

Diabetes Mellitus, Type 2 | Diabetes | Diabetes Mellitus, Type 1 | Delivery Systems

Germany
Maastricht University Medical Center

Completed

Local Pilocarpine for Relieving Dry Mouth

Patients of Advanced Age (≥ 70 Years) With a Clinical Diagnosis of Chronic Dry Mouth

Netherlands
University of Monastir
Loussaief Chawki; Nissaf Ben Alaya; Cyrine Ben Nasrallah; Manel Ben Belgacem; Hela... and other collaborators

Completed

The Effect of Vitamin D Supplementation on COVID-19 Recovery (COVID-VITD)

Covid19

Tunisia
Alcon Research

Completed

Nevanac 3-Month Safety Study With QID Dosing

Cataract

United States
Eyenovia Inc.

Completed

Eyenovia MiDD Usability Study

Intraocular Pressure

Panama
Lifelong Vision Foundation

Completed

Effect of Lifitegrast on Dry Eye Disease Signs and Symptoms (Lifitegrast)

Dry Eye

United States
Second Affiliated Hospital, School of Medicine,...

Recruiting

A Prospective Randomized Controlled Study of Immune Checkpoint Maintenance Therapy After Radiotherapy and Chemotherapy for Locally Advanced Head and Neck Tumors Based on Peripheral Blood CD8Tex Detection in Peripheral Blood

Locally Advanced Head and Neck Squamous Cell Carcinoma

China
Medical University of Vienna

Completed

Brain Natriuretic Peptide Effects on Appetite Regulating Hormones and Endothelial Derived Peptides (BNP/Appetite)

Healthy

Austria
Alfact Innovation

Unknown

Efficacy & Safety of ALF-5755 in Patients With Nonacetaminophen Severe Acute Hepatitis & Early Stage Acute Liver Failure

Liver Failure, Acute

France
Bristol-Myers Squibb

Terminated

Safety Study of BMS-844421 for Treatment of Hypercholesterolemia

Atherosclerosis | Hypercholesterolemia

Germany
Richard W Yee, MD

Not yet recruiting

The Effects and Safety of Topical Spironolactone Ophthalmic Solution, 0.005 mg/cc in Subjects With Dry Eye Disease

Dry Eye Disease

United States
Bausch & Lomb Incorporated

Completed

Safety and Efficacy of an Ophthalmic Solution in Dry Eye Disease

Dry Eye Disease

United States
Elman Retina Group

Completed

Squalamine for the Treatment in Proliferative Diabetic Retinopathy

Retinal Neovascularization

United States
Bausch & Lomb Incorporated

Completed

Efficacy Study of Bromfenac Ophthalmic Solution in Patients Undergoing Cataract Surgery

Pain | Inflammation

United States
Betaliq, Inc.
Trial Runners, LLC; Summit Analytical, LLC

Completed

Nebivolol 0.5, 1.0, or Timolol 0.5 Suspension Compared to Timolol 0.5 Solution to Treat Glaucoma/Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

United States
Prof Gérard WAEBER
Centre Hospitalier Universitaire Vaudois; University of Lausanne; Center for...

Terminated

A Double Blind Randomised Placebo-controlled Trial to Assess the Role of Iron Repletion in Glucose Homeostasis. (DIAFER)

Iron-deficiency | Safety Issues | Metabolic Disorder, Glucose | Iron Toxicity | Glucose Metabolism Disorders (Including Diabetes Mellitus) | Metabolic Side Effects of Drugs

Switzerland
Assistance Publique - Hôpitaux de Paris
Hoffmann-La Roche

Completed

Effect of the Interleukin-6 Receptor Antagonist Tocilizumab in Patients With Hand Osteoarthritis (TIDOA)

Hand Osteoarthritis

France
Institute of Liver and Biliary Sciences, India

Completed

Comparison And Outcomes Of Fluid Resucitation With 0.9% Normal Saline And 5% Albumin In Cirrhosis Patients With Sepsis Induced Hypotension

Cirrhosis With Septic Shock

India
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Hypertonic Saline Solution in Heart Failure

Heart Failure | Renal Failure | Hyponatremia

Brazil
Bausch & Lomb Incorporated

Completed

Efficacy and Safety of Bromfenac Ophthalmic Solution in Cataract Surgery

Cataract

United States
Alcon Research

Completed

A Phase III Study of Brimonidine Tartrate Ophthalmic Solution, 0.15% in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

United States
Alcon Research

Completed

Brinzolamide/Brimonidine Twice a Day (BID) Fixed Combination (FC) vs Brinzolamide BID and Brimonidine BID in Patients With Open Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma
Alcon Research

Completed

Three Month Efficacy/Safety Study With a 3-Month Safety Extension of Brinzolamide 1%/Brimonidine 0.2% vs. Brinzolamide 1% or Brimonidine 0.2%

Ocular Hypertension | Open-Angle Glaucoma
Serafino A. Marsico
Federico II University

Unknown

Inhaled Glutathione (GSH) Versus Placebo in Cystic Fibrosis

Cystic Fibrosis

Italy
Alcon Research

Completed

Fixed Combination Brinzolamide 1%/Timolol 0.5% Versus Brinzolamide 1% + Timolol 0.5% in Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma
Zurita Laboratorio Farmaceutico Ltda.

Unknown

A Study of Luffa Operculate Nasal Solution 5mg/mL Compared With Saline (NaCl 09%) for the Relief of Nasal Obstruction

Sinusitis | Rhinitis

Brazil
Polyheal Ltd.

Unknown

Study to Evaluate Polyheal-1 in Treatment of Recalcitrant Wounds

Wounds and Injuries

Israel
Santen Pharmaceutical (Taiwan) Co., LTD

Completed

Prospective, Single Center Switching Study of 0.0015% Tafluprost Ophthalmic Solution in Primary Open-angle Glaucoma and Ocular Hypertension Patients With Corneal Disorders (Switching From 0.005% Latanoprost Ophthalmic Solution)

Glaucoma, Primary Open Angle

Taiwan
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Phase 1, Open-Label Study of Latanoprost Acid Plasma Concentrations in Pediatric and Adult Glaucoma Patients Treated With Latanoprost.

Ocular Hypertension | Glaucoma

United States, Spain, Italy, Denmark, Portugal, South Africa
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Study to Assess the Efficacy of 3 Months of Latanoprost Treatment in Reducing the Intraocular Pressure in Patients With Ocular Hypertension or Open-angle Glaucoma

Ocular Hypertension | Glaucoma, Open-Angle

France
Novartis Pharmaceuticals

Completed

Efficacy, Tolerability and Safety of RKI983 (0.05% & 0.10%) vs Xalatan in Patients With POAG or Ocular Hypertension

Ocular Hypertension | Glaucoma

United States
MDbackline, LLC

Completed

The Effect Of Lifitegrast On Refractive Accuracy And Symptoms In Dry Eye Patients Undergoing Cataract Surgery

Dry Eye

United States
University of Alabama at Birmingham
Shire

Withdrawn

Effects of Xiidra on Closed Eye Tear Film Leukocytes in Dry Eye Disease

Ocular Inflammation | Dry Eye | Keratoconjunctivitis Sicca | Contact Lens Complication | Ocular Discomfort
Sohag University

Unknown

Microneedling and Latanoprost in Acrofacial Vitiligo

Vitiligo
Shire

Completed

A Study to Evaluate Efficacy and Safety of Lifitegrast in Subjects With Dry Eye (OPUS-3) (OPUS-3)

Dry Eye Disease

United States
Aurolab

Unknown

Clinical Evaluation of Efficacy of SLT to Topical Medication in Lowering IOP

Glaucoma

India
Tulane University

Not yet recruiting

The Effect of Lumify™ on Ocular Redness, Intraocular Pressure, and Eyelid Position in Glaucoma Patients

Glaucoma | Glaucoma, Open-Angle | Ptosis | Glaucoma, Primary Open Angle | Glaucoma; Drugs | Droopy Eyelid

United States

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