Search clinical trials for: DKN-01 300 mg

Total 2275 results

Rigel Pharmaceuticals

No longer available

Expanded Access of Fostamatinib in Patients With Persistent or Chronic Relapsing/Refractory ITP

Immune Thrombocytopenic Purpura
RespireRx

Completed

CX717 in the Treatment of Adult ADHD

Attention Deficit Hyperactivity Disorder
Amneal Pharmaceuticals, LLC
Symbio, LLC

Completed

Safety and Efficacy of Phenazopyridine Hydrochloride Tablets, USP 200 mg as an Analgesic for Short-Term Treatment in Female Subjects Suffering From Moderate-to-Severe Pain and Burning Upon Urination Associated With Uncomplicated Urinary Tract Infections (uUTI)

Uncomplicated Urinary Tract Infections

United States
Eisai Limited

Terminated

A Study to Evaluate the Safety and Tolerability and Explore the Efficacy of Zonisamide as add-on Therapy in Elderly Patients With Refractory Partial Seizures

Epilepsy

United Kingdom, Germany, Hungary, Switzerland, Italy, Netherlands, Poland
Obafemi Awolowo University
London School of Hygiene and Tropical Medicine; University of California, San... and other collaborators

Completed

Viral and Antiretroviral Dynamics in HIV-1 Mother-to-Child Transmission Fluids (VADICT)

Human Immunodeficiency Virus Infection

Nigeria
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Secukinumab in Subjects With Moderate to Severe Chronic Plaque-type Psoriasis

Plaque Psoriasis

China, Thailand, Philippines, Turkey, Hungary, Malaysia
Novartis

Completed

Efficacy and Safety of the Combination Aliskiren (300 mg) and Hydrochlorothiazide (25mg) to Aliskiren (300mg) Monotherapy in Patients With Staged II Hypertension (ACQUIRE)

Hypertension

Switzerland, Italy, Argentina, Germany, Turkey, United States, Ecuador, Guatemala
Fondazione Policlinico Universitario Agostino Gemelli...

Not yet recruiting

Mepolizumab in the Treatment of Patients With Severe Uncontrolled CRSwNP: a Multicentric Real Life Observational Study (MEPOREAL)

Chronic Rhinosinusitis With Nasal Polyps

Italy
Pfizer

Completed

A Study to Evaluate the Effect of Hepatic Impairment on the Pharmacokinetics of Glasdegib

Hepatic Impairment

United States
Aquinox Pharmaceuticals (Canada) Inc.

Terminated

Efficacy and Safety of AQX-1125 in Subjects With Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)

Chronic Prostatitis | Chronic Pelvic Pain Syndrome

Canada, United States
MedImmune LLC

Completed

Study to Evaluate the Safety and Efficacy of CAT-354

Asthma

Bulgaria, United Kingdom, Germany, Poland, Romania
CrystalGenomics, Inc.

Completed

Multiple Ascending Doses Study of CG400549

Healthy

Netherlands
University of California, San Francisco
San Francisco AIDS Foundation; California HIV/AIDS Research Program

Completed

Study of Truvada for HIV Pre Exposure Prophylaxis Using Daily Directly Observed Therapy to Look at Potential Interactions Between Truvada and Hormone Therapy (I-BrEATHe)

HIV Prevention | Transgender Health

United States
Medicines for Malaria Venture
Richmond Pharmacology Limited

Completed

Determine the Tolerability and Safety of Atovaquone-proguanil (ATV-PG) Co-administered With Amodiaquine (AQ)

Malaria

United Kingdom
Teva Pharmaceuticals USA

Completed

Clindamycin 300 mg Capsules in Healthy Subjects Under Fed Conditions

Healthy

Canada
Centre Hospitalier Universitaire de Saint Etienne

Recruiting

A Dose-response Study of Tranexamic Acid in Total Hip Arthroplasty (PRADO)

Arthropathy of Hip

France
Merck Sharp & Dohme LLC

Recruiting

Placebo-controlled, Study of Concurrent Chemoradiation Therapy With Pembrolizumab Followed by Pembrolizumab and Olaparib in Newly Diagnosed Treatment-Naïve Limited-Stage Small Cell Lung Cancer (LS-SCLC) (MK 7339-013/KEYLYNK-013)

Small Cell Lung Cancer

United States, Australia, Belgium, Bulgaria, Canada, China, France, Greece, Hungary, Israel, Italy, Japan, Korea, Republic of, Lithuania, Mexico, Portugal, Romania, Russian Federation, Serbia, South Africa, Spain, Turkey, Ukraine, United... and more
Mansoura Integrated Fertility Center

Completed

Is Adding E2 to P4 Luteal Support In High Responder Long Gn-RH Agonist ICSI Cycles Detrimental to Outcome? RCT

Infertility | IVF

Egypt
Nearmedic Plus LLC
OCT LLC

Completed

Phase 1 Study of PBTZ169

Tuberculosis
Ardea Biosciences, Inc.

Completed

Lesinurad Tablet Relative Bioavailability

Healthy

United States
Clinica Universidad de Navarra, Universidad de...
University of Navarrra Hospital (Clinica Universitaria)

Unknown

Concentration of Antimicrobials in Catheter-lock Solutions (CONAN)

Catheter-Related Infections | Bacteremia.

Spain
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Cardiac Safety of a Single Dose of AL-335 Administered on a Background of Simeprevir and Odalasvir and of Repeated Doses of Odalasvir Administered Alone in Healthy Participants

Healthy

United States
Yale University
National Institute on Drug Abuse (NIDA)

Completed

The Role of Neuroactive Steroids in Stress, Drug Craving and Drug Use in Cocaine Use Disorders

Cocaine-Related Disorders

United States
Novartis

Completed

Efficacy and Safety of Combination Therapy of Aliskiren/Amlodipine or Aliskiren/Amlodipine/Hydrochlorothiazide in Patients With Stage II Hypertension (ACADEMY)

Stage II Hypertension

Thailand
Shanghai Public Health Clinical Center

Not yet recruiting

Efficacy and Tolerability of DTG Plus 3TC in HIV Infected Adults With Virologically Suppression and TDF Toxicity

Acquired Immunodeficiency Syndrome
Centers for Disease Control and Prevention
Botswana Ministry of Health

Completed

Open Label Extension (OLE) of the TDF2 Study, Botswana (TDF2-OLE)

HIV Infections
Shaheed Zulfiqar Ali Bhutto Medical University

Completed

Tocilizumab and Cytokine Release Syndrome (CRS) In Covid-19 Pneumonia

Cytokine Release Syndrome | Covid-19 Pneumonia

Pakistan
Kadmon Corporation, LLC
Quotient Sciences

Completed

A Phase I Study to Evaluate the Taste of Belumosudil Oral Suspensions & Assess Relative Bioavailability

Healthy Volunteers

United Kingdom
Evandro Chagas Institute of Clinical Research

Not yet recruiting

Short Benznidazole Regimen for Chronic Phase Chagas Disease Patients (Benlatino)

Chronic Chagas Disease

Brazil
CymaBay Therapeutics, Inc.

Terminated

Study to Evaluate the Effects of Two Doses of MBX-8025 in Subjects With Primary Biliary Cirrhosis (PBC)

Primary Biliary Cirrhosis (PBC)

Germany, United States, Canada, United Kingdom, Poland
Intercept Pharmaceuticals

Active, not recruiting

Study of OCA in Combination With BZF Evaluating Efficacy, Safety and Tolerability in Participants With PBC

Primary Biliary Cholangitis

United States
Queen Mary University of London
University of Oxford; Aga Khan University; University of Bristol; Dow University...

Enrolling by invitation

Therapy for Hepatitis C Virus (HCV) in Primary Treatment Failure in Pakistan

Hepatitis C

Pakistan
Eli Lilly and Company
CoLucid Pharmaceuticals

Completed

Lasmiditan Compared to Placebo in the Acute Treatment of Migraine: (SAMURAI)

Acute Migraine

United States
Centocor, Inc.

Completed

A Study of the Pharmacokinetics of Golimumab in Japanese and Caucasian Male Subjects

Healthy Volunteers

United States
Cristina Mussini

Unknown

Evaluating Inflammatory and Immunological Changes of HIV-positive Patients Switching to DTG Dual Regimen Compared to Those Switching to a Triple Drugs Regimen (B/F/TAF)

HIV Infections
Daiichi Sankyo, Inc.

Completed

Effect of Low-Fat Food on Pexidartinib Pharmacokinetics in Healthy Volunteers

Healthy Volunteers

United States
Warner Chilcott

Completed

Delayed Release (DR) Risedronate Compared to Immediate Release (IR) in Postmenopausal Women

Postmenopausal Osteoporosis

United States
Gilead Sciences

Completed

ONCE - Only Nocturnal Combination Evaluation of Antiretroviral-Experienced HIV 1 Infected Subjects Switching to Atripla (ONCE)

HIV Infections

United Kingdom
Chicago Headache Center & Research Institute
AbbVie

Recruiting

Ubrogepant treatmeNt in mIgraine Patients Utilizing mOnoclonal aNtibodies (UNION)

Headache, Migraine

United States
Alkermes, Inc.

Completed

ALK21-003: Study of Medisorb® Naltrexone (VIVITROL®) in Alcohol-Dependent Adults

Alcoholism
Novartis Pharmaceuticals

Completed

Study to Evaluate the Safety and Efficacy of Secukinumab 300 mg and 150 mg in Adult Patients With Active Psoriatic Arthritis (PsA) After 16 Weeks of Treatment Compared to Placebo

Psoriatic Arthritis

United States, Puerto Rico
Desitin Arzneimittel GmbH
BioPharma Services, Inc

Completed

Bioavailability of Orfiril Long 500 mg Prolonged-Release Minitablets and Ergenyl Chrono 500 mg Prolonged-Release Tablets

Multiple Drug Use

Canada
Frank Lippert
The Borrow Foundation

Completed

An in Situ Study on the Impact of Fluoride Dose and Concentration in Milk on Its Anti-caries Efficacy

Caries

United States
Università degli Studi di Ferrara
GlaxoSmithKline

Recruiting

Severe Asthma Exacerbations and Mepolizumab Treatment (ESAM-BIO)

Severe Asthma

Italy
Mylan Pharmaceuticals Inc

Completed

Food Study of Glipizide and Metformin HCl Tablets 5 mg/500 mg to Metaglip® Tablets 5 mg/500 mg

Healthy

United States
Madrigal Pharmaceuticals, Inc.

Enrolling by invitation

A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Multiple Oral Doses (6 Days) of 100 mg Resmetirom in Subjects With Severe Renal Impairment and in Matched Healthy Control Subjects With Normal Renal Function

Renal Impairment

United States
Asmacure Ltée

Completed

Safety, Tolerability and Clinical Activity of ASM-024 in Stable Moderate Asthma

Asthma

Canada
International Partnership for Microbicides, Inc.
National Institutes of Health (NIH)

Completed

PK and Safety Study of Vaginal Rings Containing Dapivirine and Levonorgestrel (DAP/LNG)

HIV Prevention

United States
MedImmune LLC

Completed

A Study of the Efficacy and Safety of MEDI-546 in Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United States, Brazil, Bulgaria, Czech Republic, Korea, Republic of, Mexico, Peru, Hungary, Poland, Romania, Ukraine, Taiwan, India, Colombia
Kissei Pharmaceutical Co., Ltd.

Completed

Extension to Study on Efficacy and Safety of Linzagolix for the Treatment of Endometriosis-associated Pain (EDELWEISS 6)

Endometriosis

United States, Austria, Bulgaria, Czechia, France, Poland, Romania, Spain, Ukraine

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