Search clinical trials for: Daptomycin

Total 187 results

Hospices Civils de Lyon

Unknown

Description of Eosinophilic Pneumonia in BJI/PJI Treated by Daptomycin

Bone and Joint Infection | Dactinomycin Adverse Reaction

France
Cubist Pharmaceuticals LLC

Terminated

Cubicin(R) for Complicated Post-surgical Wound Infections (PSW)

Wound Infections
Cubist Pharmaceuticals LLC

Terminated

Daptomycin for the Treatment of Infections Due to Gram-Positive Bacteria

Gram-Positive Bacterial Infections
Cubist Pharmaceuticals LLC

Completed

Study of Single Dose Daptomycin in Pediatric Patients With Gram-positive Infection for Which They Are Receiving Standard Antibiotics

Gram-positive Bacterial Infections

United States
Cubist Pharmaceuticals LLC

Completed

Comparative Study of Cidecin™ (Daptomycin) to Rocephin® (Ceftriaxone) in the Treatment of Moderate to Severe Community-Acquired Acute Bacterial Pneumonia

Pneumonia, Bacterial
Cubist Pharmaceuticals LLC

Completed

Safety Study to Evaluate Daptomycin in Non-infected Adults Who Are Either on Hemodialysis or Continuous Ambulatory Peritoneal Dialysis (MK-3009-021)

End-Stage Renal Disease
Cubist Pharmaceuticals LLC

Terminated

Phase 4 Efficacy and Safety Study of Cubicin® With and Without Combination Therapy in S. Aureus Infective Endocarditis (SAIE)

Infective Endocarditis

United States
Cubist Pharmaceuticals LLC

Completed

Study to Evaluate Daptomycin Given During Dialysis and After Dialysis

End-stage Renal Disease | Renal Failure Chronic Requiring Hemodialysis

United States
Cubist Pharmaceuticals LLC

Completed

PK and Safety Evaluation of Daptomycin in Children Ages 2-6 With Proven or Suspected Gram-positive Infections

Gram Positive Infection | Concurrent Antibiotic Treatment

United States
Cubist Pharmaceuticals LLC

Completed

Daptomycin in the Treatment of Subjects With Infective Endocarditis or Bacteremia Due to S. Aureus

Bacteremia | Bacterial Endocarditis
Cubist Pharmaceuticals LLC

Completed

Study of Cidecin™ (Daptomycin) to Rocephin® (Ceftriaxone) in the Treatment of Moderate to Severe Community-Acquired Acute Bacterial Pneumonia Due to S. Pneumoniae

Pneumonia, Bacterial
University Hospital, Caen

Completed

Pharmacokinetics Study of Intraperitoneal Administration of Daptomycin in Peritoneal Infection (DAPTODP)

Peritoneal Infection

France
Merck Sharp & Dohme LLC

Completed

A Study of MK-3009 in Japanese Patients With Skin or Blood Stream Infections Caused by Methicillin-resistant Staphylococcus Aureus (MK-3009-002)

Staphylococcal Infection
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Withdrawn

Daptomycin or Vancomycin in Treating Bacteria in the Blood in Patients With Neutropenia Caused By Chemotherapy

Unspecified Childhood Solid Tumor, Protocol Specific | Neutropenia | Unspecified Adult Solid Tumor, Protocol Specific | Infection

United States
Cubist Pharmaceuticals LLC

Terminated

Daptomycin in the Treatment of Patients With Renal Insufficiency and Complicated Skin and Skin Structure Infections

Soft Tissue Infections

United States
Cubist Pharmaceuticals LLC

Terminated

Phase 2 Study of Safety, Efficacy, and Pharmacokinetics of Higher Doses of Daptomycin and Vancomycin in MRSA Bacteremia (HDSAB)

Infective Endocarditis | Endocarditis, Bacterial

United States
Merck Sharp & Dohme LLC

Completed

Safety, Efficacy, and Pharmacokinetics (PK) of Daptomycin (MK-3009) in Japanese Pediatric Subjects With Complicated Skin and Soft Tissue Infections (cSSTI) and Bacteremia (MK-3009-029)

Skin Diseases, Infectious | Bacteremia | Soft Tissue Infections

Japan
University of Maryland, Baltimore
Cubist Pharmaceuticals LLC

Completed

Daptomycin for the Treatment of Severe Necrotizing Soft-Tissue Infections

Fasciitis, Necrotizing | Fournier's Gangrene | Severe Necrotizing Skin and Soft Tissue Infections

United States
Lundquist Institute for Biomedical Innovation at...
Western University of Health Sciences; Hartford Hospital; Cubist Pharmaceuticals...

Completed

Pharmacokinetics of Daptomycin During Cardiopulmonary Bypass Surgery

Staphylococcus Aureus | Surgical Site Infection | Late Effects of Surgery

United States
Duke University
Cubist Pharmaceuticals LLC

Terminated

A Pilot Study of Daptomycin for Antimicrobial Prophylaxis

Antimicrobial Prophylaxis

United States
Assistance Publique - Hôpitaux de Paris
Novartis

Terminated

Daptomycin Versus Vancomycin in the Treatment of Nosocomial or Healthcare-associated MRSA Bacteremia (DAVASAB)

Nosocomial Infection | Healthcare-associated Infection

France
University of Padova

Terminated

Daptomycin + Meropenem Versus Ceftazidime in the Treatment of Nosocomial Spontaneous Bacterial Peritonitis

Cirrhosis | Ascites | Nosocomial Spontaneous Bacterial Peritonitis

Italy
Hospices Civils de Lyon

Recruiting

Pharmacokinetics and Toxicodynamics of Daptomycin in Bone and Joint Infections (PKTOXDAP)

Bone and Joint Infection | Dactinomycin Adverse Reaction

France
Miquel Pujol
Hospital Universitari de Bellvitge

Completed

Efficacy of Daptomycin Plus Fosfomycin Versus Daptomycin for Treatment of MRSA Bacteremia

Staph Aureus Methicillin Resistant Bacteremia

Spain
Chang Gung Memorial Hospital

Not yet recruiting

Preoperative Daptomycin Prophylaxis in Two-Stage Exchange Arthroplasty: A Prospective, Randomized, Double-Blinded Trial

Periprosthetic Joint Infection

Taiwan
Methodist Health System

Enrolling by invitation

Utility Assessment of a Pharmacy-to-Dose Daptomycin

Antibiotics Causing Adverse Effects in Therapeutic Use

United States
Aziende Chimiche Riunite Angelini Francesco S.p.A
Hippocrates Research

Completed

Retrospective Effectiveness Study of Dalbavancin and Other Standard of Care of the Same Class in Patients With ABSSSI (REDS)

Acute Bacterial Skin and Skin Structure Infection

Greece, Italy
University Hospital, Montpellier

Completed

Retrospective Analysis of Nephrotoxicity During Daptomycin Versus Vancomycin Treatments in High Risk Patients (DVN)

Surgical Site Infection | Infective Endocarditis | Mediastinitis | Infection Related to Ventricular Assist Device | Infection Related to Vascular Prothesis

France
Jiangsu Hengrui Pharmaceutical Co., Ltd.

Unknown

The Efficacy and Safety of Daptomycin in the Treatment of Gram-positive Bacterial Infection.

Antibiotic

China
Novartis

Terminated

Safety and Efficacy of Daptomycin for the Treatment of Complicated Skin and Skin-structure Infections

Staphylococcal Skin Infections

Italy
University of Zurich

Unknown

Daptomycin Pharmacokinetics in Critically Ill Patients Undergoing Continuous Veno-venous Hemodiafiltration, a Dose Finding Study

Gram-Positive Bacterial Infections

Switzerland
Zhongnan Hospital

Unknown

A Pharmacokinetics Study of Daptomycin in Critically Ill Patients and Effects of Daptomycin on Kidney

Infection | Outcome, Fatal

China
University of Zurich

Withdrawn

Evaluation of Single-dose Pharmacokinetics of Intravenous Daptomycin in Patients With Thermal Injury

Burn Injury

Switzerland
University of Zurich

Unknown

Daptomycin Pharmacokinetics in Continuous Veno-venous Hemodiafiltration

Bacteremia

Switzerland
Vancouver Island Health Authority

Recruiting

Ceftriaxone as Home IV for Staph Infections

Abscess | Staphylococcal Infections | Diabetic Foot Infection | Osteomyelitis | Vertebral Osteomyelitis | CNS Infection | Septic Arthritis | Coagulase Negative Staphylococcal Infection

Canada
University Hospital, Caen

Completed

Subcutaneous Daptomycin in Healthy Volunteers (DAPTOSC) (DAPTOSC)

Antibiotics | Subcutaneous Injection | Daptomycin

France
University Hospital Tuebingen

Completed

Daptomycin Concentration in Drainage Fluid and Blood Samples of ICU Patients

Heart Assist Device

Germany
Weill Medical College of Cornell University

Terminated

Daptomycin as an Adjuvant Agent in the Treatment of Enterococcal Native Valve Endocarditis.

Endocarditis, Bacterial

United States
AstraZeneca

Completed

Pharmacokinetic Study of Daptomycin in Healthy Chinese Subjects Living in China

Healthy

China
University of Pittsburgh
Cubist Pharmaceuticals LLC

Terminated

Cerebrospinal Fluid Pharmacokinetics of Daptomycin

Meningitis

United States
Centre Hospitalier Universitaire Dijon

Recruiting

Adjunction of Daptomycin for the Treatment of Pneumococcal Meningitis (AddaMAP)

Pneumococcal Meningitis

France
M.D. Anderson Cancer Center
Cubist Pharmaceuticals LLC

Completed

Catheter Related - Gram Positive Bloodstream Infections

Bloodstream Infection

United States
Cubist Pharmaceuticals LLC

Completed

Pharmacokinetics (PK) and Safety Evaluation of Daptomycin in Children Ages 3-24 Months With Proven or Suspected Gram-positive Infections or Peri-Operative Subjects Receiving Prophylactic Antibiotics

Gram Positive Bacterial Infection

United States
University of Oklahoma
Cubist Pharmaceuticals LLC

Completed

Study of the Pharmacokinetics of Daptomycin in Children With Renal Disease

Chronic Kidney Disease | Bacterial Infection

United States
University of Michigan
Cubist Pharmaceuticals LLC

Completed

Pharmacokinetics of Daptomycin in Critically Ill Patients Receiving Continuous Venovenous Hemodialysis (CVVHD)

Hemodialysis | Critically Ill

United States
Andrej Trampuz
University of Lausanne Hospitals; Schulthess Klinik; Kantonsspital Liestal

Unknown

Daptomycin With Rifampin for Treatment of Staphylococcal Prosthetic Joint Infection (Dapto-Studie)

Staphylococcal Infections

Switzerland
Cubist Pharmaceuticals LLC

Completed

Study Comparing CUBICIN® (Daptomycin for Injection) With Vancomycin in Cellulitis or Erysipelas

Cellulitis

United States
OHSU Knight Cancer Institute

Completed

Daptomycin in Treating Neutropenia and Fever in Patients With Cancer

Hot Flashes | Neutropenia | Fever | Unspecified Adult Solid Tumor, Protocol Specific | Infection | Sweating

United States
University Hospital Inselspital, Berne

Terminated

Daptomycin in Pediatric Patients With Bacterial Meningitis

Meningitis

Switzerland
Poitiers University Hospital

Completed

Population Pharmacokinetic (PK) Study of Multiple Doses of Cubicin® (Daptomycin) 10 mg/kg in Critical Care Patients Having Bacteremia, Endocarditis or Skin Soft Tissue Infections Due to Gram Positive Bacteria With Various Degrees of Renal Failure (DAPTOREA)

Renal Failure | Critical Care | Gram Positive Bacteria

France

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